Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 3 May 2002:
Vol. 296. no. 5569, pp. 864 - 868
DOI: 10.1126/science.1069863

Review

Planetary Biology--Paleontological, Geological, and Molecular Histories of Life

Steven A. Benner,1234* M. Daniel Caraco,145 J. Michael Thomson,2 Eric A. Gaucher3

The history of life on Earth is chronicled in the geological strata, the fossil record, and the genomes of contemporary organisms. When examined together, these records help identify metabolic and regulatory pathways, annotate protein sequences, and identify animal models to develop new drugs, among other features of scientific and biomedical interest. Together, planetary analysis of genome and proteome databases is providing an enhanced understanding of how life interacts with the biosphere and adapts to global change.

1 Department of Chemistry,
2 Department of Anatomy and Cell Biology, and
3 NASA Astrobiology Institute, Department of Chemistry, University of Florida, Gainesville FL, 32611-7200, USA.
4 Foundation for Applied Molecular Evolution, Post Office Box 13174, Gainesville FL, 32604, USA.
5 Department of Chemistry, ETH Hönggerberg, CH-8093 Zürich, Switzerland.
*   To whom correspondence should be addressed. E-mail: benner{at}chem.ufl.edu


Read the Full Text



THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Prevolutionary dynamics and the origin of evolution.
M. A. Nowak and H. Ohtsuki (2008)
PNAS 105, 14924-14927
   Abstract »    Full Text »    PDF »
Relaxation of yeast mitochondrial functions after whole-genome duplication.
H. Jiang, W. Guan, D. Pinney, W. Wang, and Z. Gu (2008)
Genome Res. 18, 1466-1471
   Abstract »    Full Text »    PDF »
The timing of eukaryotic evolution: Does a relaxed molecular clock reconcile proteins and fossils?.
E. J. P. Douzery, E. A. Snell, E. Bapteste, F. Delsuc, and H. Philippe (2004)
PNAS 101, 15386-15391
   Abstract »    Full Text »    PDF »
Evolutionary, Structural and Biochemical Evidence for a New Interaction Site of the Leptin Obesity Protein.
E. A. Gaucher, M. M. Miyamoto, and S. A. Benner (2003)
Genetics 163, 1549-1553
   Abstract »    Full Text »    PDF »



To Advertise     Find Products


Science. ISSN 0036-8075 (print), 1095-9203 (online)