Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 1 March 2002:
Vol. 295. no. 5560, pp. 1695 - 1698
DOI: 10.1126/science.1067595
Prev | Table of Contents | Next

Reports

Micro/Nano Encapsulation via Electrified Coaxial Liquid Jets

I. G. Loscertales,1* A. Barrero,2* I. Guerrero,2 R. Cortijo,1 M. Marquez,34 A. M. Gañán-Calvo2

We report a method to generate steady coaxial jets of immiscible liquids with diameters in the range of micrometer/nanometer size. This compound jet is generated by the action of electro-hydrodynamic (EHD) forces with a diameter that ranges from tens of nanometers to tens of micrometers. The eventual jet breakup results in an aerosol of monodisperse compound droplets with the outer liquid surrounding or encapsulating the inner one. Following this approach, we have produced monodisperse capsules with diameters varying between 10 and 0.15 micrometers, depending on the running parameters.

1 Escuela Técnica Superior de Ingenieros Industriales, Universidad de Málaga, Plaza El Ejido, S/N Malaga 29013, Spain.
2 Escuela Superior de Ingenieros, Universidad de Sevilla, Camino de los Descubrimientos S/N, 41092 Seville, Spain.
3 Kraft Foods R&D, The Nanotechnology Lab, 801 Waukegan Road, Glenview, IL 60025, USA.
4 Los Alamos National Laboratory, Chemical Sciences and Technology Division, Los Alamos, NM 87545, USA.
*   To whom correspondence should be addressed. E-mail: loscertales{at}uma.es; barrero{at}eurus2.us.es

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Droplet microfluidic technology for single-cell high-throughput screening.
E. Brouzes, M. Medkova, N. Savenelli, D. Marran, M. Twardowski, J. B. Hutchison, J. M. Rothberg, D. R. Link, N. Perrimon, and M. L. Samuels (2009)
PNAS 106, 14195-14200
   Abstract »    Full Text »    PDF »
Preparation of suspensions of phospholipid-coated microbubbles by coaxial electrohydrodynamic atomization.
U Farook, E Stride, and M.J Edirisinghe (2009)
J R Soc Interface 6, 271-277
   Abstract »    Full Text »    PDF »
Generation of multilayered structures for biomedical applications using a novel tri-needle coaxial device and electrohydrodynamic flow.
Z Ahmad, H.B Zhang, U Farook, M Edirisinghe, E Stride, and P Colombo (2008)
J R Soc Interface 5, 1255-1261
   Abstract »    Full Text »    PDF »
Preparation and Characterization of Core--Shell Structured Nanofibers by Coaxial Electrospinning.
Xiao Jian Han, Zhengming Huang, Chuanglong He, and Ling Liu (2007)
High Performance Polymers 19, 147-159
   Abstract »    PDF »
A novel method for the preparation of biodegradable microspheres for protein drug delivery.
R Pareta and M.J Edirisinghe (2006)
J R Soc Interface 3, 573-582
   Abstract »    Full Text »    PDF »
Monodisperse Double Emulsions Generated from a Microcapillary Device.
A. S. Utada, E. Lorenceau, D. R. Link, P. D. Kaplan, H. A. Stone, and D. A. Weitz (2005)
Science 308, 537-541
   Abstract »    Full Text »    PDF »
Colloidosomes: Selectively Permeable Capsules Composed of Colloidal Particles.
A. D. Dinsmore, M. F. Hsu, M. G. Nikolaides, M. Marquez, A. R. Bausch, and D. A. Weitz (2002)
Science 298, 1006-1009
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)