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Science 14 December 2001: Vol. 294. no. 5550, pp. 2310 - 2314 DOI: 10.1126/science.1065889
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Review
Bayesian Inference of Phylogeny and Its Impact on Evolutionary Biology
John P. Huelsenbeck,1*
Fredrik Ronquist,2
Rasmus Nielsen,3
Jonathan P. Bollback1
As a discipline, phylogenetics is becoming transformed by a
flood of molecular data. These data allow broad questions to be asked
about the history of life, but also present difficult statistical and
computational problems. Bayesian inference of phylogeny brings a new
perspective to a number of outstanding issues in evolutionary biology,
including the analysis of large phylogenetic trees and complex
evolutionary models and the detection of the footprint of natural
selection in DNA sequences.
1 Department of Biology, University of
Rochester, Rochester, NY 14627, USA.
2 Department of
Systematic Zoology, Evolutionary Biology Centre, Uppsala University,
Norbyv. 18D, SE-752 36 Uppsala, Sweden.
3 Department
of Biometrics, Cornell University, Ithaca, NY 14853-1643, USA.
*
To whom correspondence should be addressed. E-mail:
johnh{at}brahms.biology.rochester.edu
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