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Science 19 October 2001:
Vol. 294. no. 5542, pp. 595 - 598
DOI: 10.1126/science.1062028

Reports

Integration Between the Epibranchial Placodes and the Hindbrain

Jo Begbie, Anthony Graham*

Developmental integration results from coordination among components of different embryonic fields to realize the later anatomical and functional relationships. We demonstrate that in the chick head, integration between the epibranchial placodes and the hindbrain is achieved as the neuroglial hindbrain crest cells guide the epibranchial neuronal cells inward to establish their central connections. This work defines a role for the neuroglial hindbrain crest in organizing the afferent innervation of the hindbrain.

Medical Research Council (MRC) Centre for Developmental Neurobiology, Fourth Floor, New Hunts House, Guys Campus, Kings College London, London SE1 9RT, UK.
*   To whom correspondence should be addressed. E-mail: anthony.graham{at}kcl.ac.uk


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