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Science 9 February 2001:
Vol. 291. no. 5506, pp. 1023 - 1026
DOI: 10.1126/science.291.5506.1023

Reports

Surface-Directed Liquid Flow Inside Microchannels

Bin Zhao,1 Jeffrey S. Moore,1* David J. Beebe2

Self-assembled monolayer chemistry was used in combination with either multistream laminar flow or photolithography to pattern surface free energies inside microchannel networks. Aqueous liquids introduced into these patterned channels are confined to the hydrophilic pathways, provided the pressure is maintained below a critical value. The maximum pressure is determined by the surface free energy of the liquid, the advancing contact angle of the liquid on the hydrophobic regions, and the channel depth. Surface-directed liquid flow was used to create pressure-sensitive switches inside channel networks. The ability to confine liquid flow inside microchannels with only two physical walls is expected to be useful in applications where a large gas-liquid interface is critical, as demonstrated here by a gas-liquid reaction.

1 The Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
2 Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
*   To whom correspondence should be addressed. E-mail: moore{at}scs.uiuc.edu


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