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Science 15 December 2000:
Vol. 290. no. 5499, pp. 2114 - 2117
DOI: 10.1126/science.290.5499.2114
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Research Articles

The Origins of Genomic Duplications in Arabidopsis

Todd J. Vision,1* Daniel G. Brown,2 Steven D. Tanksley3

Large segmental duplications cover much of the Arabidopsis thaliana genome. Little is known about their origins. We show that they are primarily due to at least four different large-scale duplication events that occurred 100 to 200 million years ago, a formative period in the diversification of the angiosperms. A better understanding of the complex structural history of angiosperm genomes is necessary to make full use of Arabidopsis as a genetic model for other plant species.

1 USDA-ARS Center for Agricultural Bioinformatics, 604 Rhodes Hall, Cornell University, Ithaca, NY 14853, USA.
2 Whitehead Institute/MIT Center for Genome Research, 320 Charles Street, Cambridge, MA 02141, USA.
3 Departments of Plant Breeding and Plant Biology, 252 Emerson Hall, Cornell University, Ithaca, NY 14853, USA.
*   To whom correspondence should be addressed. E-mail: tv23{at}cornell.edu

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