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Science 24 March 2000: Vol. 287. no. 5461, pp. 2222 - 2224 DOI: 10.1126/science.287.5461.2222
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Viewpoint
A Drosophila Complementary DNA Resource
Gerald M. Rubin,
123
Ling Hong,
13
Peter Brokstein,
13
Martha Evans-Holm,
13
Erwin Frise,
13
Mark Stapleton,
4
Damon A. Harvey
123
Collections of nonredundant, full-length
complementary DNA (cDNA) clones for each of the model organisms and
humans will be important resources for studies of gene structure and
function. We describe a general strategy for producing such collections and its implementation, which so far has generated a set of cDNAs corresponding to over 40% of the genes in the fruit fly
Drosophila melanogaster.
1 Berkeley Drosophila Genome
Project,
2 Howard Hughes Medical Institute, and
3 Department of Molecular and Cell Biology,
University of California, Berkeley, CA 94720-3200, USA.
4 Berkeley Drosophila Genome Project,
Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Read the Full Text
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- Mitochondrial and Cytoplasmic Thioredoxin Reductase Variants Encoded by a Single Drosophila Gene Are Both Essential for Viability.
- F. Missirlis, J. K. Ulschmid, M. Hirosawa-Takamori, S. Gronke, U. Schafer, K. Becker, J. P. Phillips, and H. Jackle (2002)
J. Biol. Chem.
277, 11521-11526
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- A question of size: the eukaryotic proteome and the problems in defining it.
- P. M. Harrison, A. Kumar, N. Lang, M. Snyder, and M. Gerstein (2002)
Nucleic Acids Res.
30, 1083-1090
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- Timing and Targeting of P-Element Local Transposition in the Male Germline Cells of Drosophila melanogaster.
- B. Timakov, X. Liu, I. Turgut, and P. Zhang (2002)
Genetics
160, 1011-1022
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- SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila.
- J. A. Zallen, Y. Cohen, A. M. Hudson, L. Cooley, E. Wieschaus, and E. D. Schejter (2002)
J. Cell Biol.
156, 689-701
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- Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper.
- B. Stronach and N. Perrimon (2002)
Genes & Dev.
16, 377-387
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- Composition of Drosophila melanogaster Proteome Involved in Fucosylated Glycan Metabolism.
- C. Roos, M. Kolmer, P. Mattila, and R. Renkonen (2002)
J. Biol. Chem.
277, 3168-3175
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- Functional antagonism between E2F family members.
- M. V. Frolov, D. S. Huen, O. Stevaux, D. Dimova, K. Balczarek-Strang, M. Elsdon, and N. J. Dyson (2001)
Genes & Dev.
15, 2146-2160
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- Map Position and Expression of the Genes in the 38 Region of Drosophila.
- H. Butler, S. Levine, X. Wang, S. Bonyadi, G. Fu, P. Lasko, B. Suter, and R. Doerig (2001)
Genetics
158, 1597-1614
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- The cyclope Gene of Drosophila Encodes a Cytochrome c Oxidase Subunit VIc Homolog.
- S. Szuplewski and R. Terracol (2001)
Genetics
158, 1629-1643
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- Redundant function of Runt Domain binding partners, Big brother and Brother, during Drosophila development.
- J. S. Kaminker, R. Singh, T. Lebestky, H. Yan, and U. Banerjee (2001)
Development
128, 2639-2648
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- aubergine encodes a Drosophila polar granule component required for pole cell formation and related to eIF2C.
- A. N. Harris and P. M. Macdonald (2001)
Development
128, 2823-2832
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- Spatial and temporal control of RNA stability.
- A. Bashirullah, R. L. Cooperstock, and H. D. Lipshitz (2001)
PNAS
98, 7025-7028
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- Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila.
- W. J. Swanson, A. G. Clark, H. M. Waldrip-Dail, M. F. Wolfner, and C. F. Aquadro (2001)
PNAS
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- From First Base: The Sequence of the Tip of the X Chromosome of Drosophila melanogaster, a Comparison of Two Sequencing Strategies.
- P. V. Benos, M. K. Gatt, L. Murphy, D. Harris, B. Barrell, C. Ferraz, S. Vidal, C. Brun, J. Demaille, E. Cadieu, et al. (2001)
Genome Res.
11, 710-730
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- Distinctive Features of Drosophila Alternative Splicing Factor RS Domain: Implication for Specific Phosphorylation, Shuttling, and Splicing Activation.
- E. Allemand, R. Gattoni, H.-M. Bourbon, J. Stevenin, J. F. Cáceres, J. Soret, and J. Tazi (2001)
Mol. Cell. Biol.
21, 1345-1359
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