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Science 24 March 2000:
Vol. 287. no. 5461, pp. 2222 - 2224
DOI: 10.1126/science.287.5461.2222

Viewpoint

A Drosophila Complementary DNA Resource

Gerald M. Rubin, 123 Ling Hong, 13 Peter Brokstein, 13 Martha Evans-Holm, 13 Erwin Frise, 13 Mark Stapleton, 4 Damon A. Harvey 123

Collections of nonredundant, full-length complementary DNA (cDNA) clones for each of the model organisms and humans will be important resources for studies of gene structure and function. We describe a general strategy for producing such collections and its implementation, which so far has generated a set of cDNAs corresponding to over 40% of the genes in the fruit fly Drosophila melanogaster.

1 Berkeley Drosophila Genome Project,
2 Howard Hughes Medical Institute, and
3 Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3200, USA.
4 Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.


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Genetics 158, 1597-1614
   Abstract »    Full Text »    PDF »
The cyclope Gene of Drosophila Encodes a Cytochrome c Oxidase Subunit VIc Homolog.
S. Szuplewski and R. Terracol (2001)
Genetics 158, 1629-1643
   Abstract »    Full Text »    PDF »
Redundant function of Runt Domain binding partners, Big brother and Brother, during Drosophila development.
J. S. Kaminker, R. Singh, T. Lebestky, H. Yan, and U. Banerjee (2001)
Development 128, 2639-2648
   Abstract »    Full Text »    PDF »
aubergine encodes a Drosophila polar granule component required for pole cell formation and related to eIF2C.
A. N. Harris and P. M. Macdonald (2001)
Development 128, 2823-2832
   Abstract »    Full Text »    PDF »
Spatial and temporal control of RNA stability.
A. Bashirullah, R. L. Cooperstock, and H. D. Lipshitz (2001)
PNAS 98, 7025-7028
   Abstract »    Full Text »    PDF »
Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila.
W. J. Swanson, A. G. Clark, H. M. Waldrip-Dail, M. F. Wolfner, and C. F. Aquadro (2001)
PNAS
   Abstract »    Full Text »    PDF »
From First Base: The Sequence of the Tip of the X Chromosome of Drosophila melanogaster, a Comparison of Two Sequencing Strategies.
P. V. Benos, M. K. Gatt, L. Murphy, D. Harris, B. Barrell, C. Ferraz, S. Vidal, C. Brun, J. Demaille, E. Cadieu, et al. (2001)
Genome Res. 11, 710-730
   Abstract »    Full Text »
Distinctive Features of Drosophila Alternative Splicing Factor RS Domain: Implication for Specific Phosphorylation, Shuttling, and Splicing Activation.
E. Allemand, R. Gattoni, H.-M. Bourbon, J. Stevenin, J. F. Cáceres, J. Soret, and J. Tazi (2001)
Mol. Cell. Biol. 21, 1345-1359
   Abstract »    Full Text »



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