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Science 24 December 1999:
Vol. 286. no. 5449, pp. 2524 - 2525
DOI: 10.1126/science.286.5449.2524
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Reports

Linkage Disequilibrium and Recombination in Hominid Mitochondrial DNA

Philip Awadalla, 1 Adam Eyre-Walker, 2* John Maynard Smith 2

The assumption that human mitochondrial DNA is inherited from one parent only and therefore does not recombine is questionable. Linkage disequilibrium in human and chimpanzee mitochondrial DNA declines as a function of the distance between sites. This pattern can be attributed to one mechanism only: recombination.

1 Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 1JT, UK.
2 Centre for the Study of Evolution and School of Biological Sciences, University of Sussex, Brighton BN1 9QG, UK.
*   To whom correspondence should be addressed. E-mail: a.c.eyre-walker{at}sussex.ac.uk

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