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Science 26 February 1999:
Vol. 283. no. 5406, pp. 1279 - 1282
DOI: 10.1126/science.283.5406.1279
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Review

The Looming Threat of Bioterrorism

Donald A. Henderson

Biological weapons have recently attracted the attention and the resources of the nation. Discerning the nature of the threat of bioweapons as well as appropriate responses to them requires greater attention to the biological characteristics of these instruments of war and terror. The dominant paradigm of a weapon as a nuclear device that explodes or a chemical cloud that is set adrift leaves us ill-equipped conceptually and practically to assess and thus to prevent the potentially devastating effects of bioterrorism. Strengthening the public health and infectious disease infrastructure is an effective step toward averting the suffering that could be wrought by a terrorist's use of a biological agent.

The author is at the Johns Hopkins Center for Civilian Biodefense Studies, Johns Hopkins School of Public Health, Suite 850, Candler Building, 111 Market Place, Baltimore, MD 21202, USA.

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N. Engl. J. Med. 346, 1265-1274
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Diagnosis and Management of Smallpox.
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N. Engl. J. Med. 346, 1300-1308
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Science. ISSN 0036-8075 (print), 1095-9203 (online)