Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 30 October 1998:
Vol. 282. no. 5390, pp. 952 - 954
DOI: 10.1126/science.282.5390.952
Prev | Table of Contents

Reports

Haldane's Rule in Taxa Lacking a Hemizygous X

Daven C. Presgraves, H. Allen Orr

Haldane's rule states that species hybrids of the XY sex are preferentially sterile or inviable. In all taxa known to obey this rule, the Y is inert and X-linked genes show full expression in XY individuals. Until recently, all theories of Haldane's rule depended on this hemizygosity. A test of Haldane's rule in animals lacking a hemizygous sex--mosquitoes having two functional sex chromosomes in both sexes--reveals that these species show Haldane's rule for sterility but not inviability. A related group having a "normal" hemizygous X obeys Haldane's rule for both sterility and inviability. These results support the faster male and dominance theories of Haldane's rule.

Department of Biology, University of Rochester, Rochester, NY 14627, USA.

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
A Complex Genetic Basis to X-Linked Hybrid Male Sterility Between Two Species of House Mice.
J. M. Good, M. D. Dean, and M. W. Nachman (2008)
Genetics 179, 2213-2228
   Abstract »    Full Text »    PDF »
Comparative Genetics of Hybrid Incompatibility: Sterility in Two Solanum Species Crosses.
L. C. Moyle and T. Nakazato (2008)
Genetics 179, 1437-1453
   Abstract »    Full Text »    PDF »
Accelerated Mitochondrial Evolution and "Darwin's Corollary": Asymmetric Viability of Reciprocal F1 Hybrids in Centrarchid Fishes.
D. I. Bolnick, M. Turelli, H. Lopez-Fernandez, P. C. Wainwright, and T. J. Near (2008)
Genetics 178, 1037-1048
   Abstract »    Full Text »    PDF »
Genome-wide patterns of gene flow across a house mouse hybrid zone.
K. C. Teeter, B. A. Payseur, L. W. Harris, M. A. Bakewell, L. M. Thibodeau, J. E. O'Brien, J. G. Krenz, M. A. Sans-Fuentes, M. W. Nachman, and P. K. Tucker (2008)
Genome Res. 18, 67-76
   Abstract »    Full Text »    PDF »
Asymmetric Postmating Isolation: Darwin's Corollary to Haldane's Rule.
M. Turelli and L. C. Moyle (2007)
Genetics 176, 1059-1088
   Abstract »    Full Text »    PDF »
A Simple Genetic Incompatibility Causes Hybrid Male Sterility in Mimulus.
A. L. Sweigart, L. Fishman, and J. H. Willis (2006)
Genetics 172, 2465-2479
   Abstract »    Full Text »    PDF »
Patterns of male sterility in a grasshopper hybrid zone imply accumulation of hybrid incompatibilities without selection.
D. M Shuker, K. Underwood, T. M King, and R. K Butlin (2005)
Proc R Soc B 272, 2491-2497
   Abstract »    Full Text »    PDF »
Evolution of RAG-1 in Polyploid Clawed Frogs.
B. J. Evans, D. B. Kelley, D. J. Melnick, and D. C. Cannatella (2005)
Mol. Biol. Evol. 22, 1193-1207
   Abstract »    Full Text »    PDF »
Genetics of Hybrid Incompatibility Between Lycopersicon esculentum and L. hirsutum.
L. C. Moyle and E. B. Graham (2005)
Genetics 169, 355-373
   Abstract »    Full Text »    PDF »
Molecular Evolution of Sex-Biased Genes in Drosophila.
Z. Zhang, T. M. Hambuch, and J. Parsch (2004)
Mol. Biol. Evol. 21, 2130-2139
   Abstract »    Full Text »    PDF »
Population Genetics of Polymorphism and Divergence for Diploid Selection Models With Arbitrary Dominance.
S. Williamson, A. Fledel-Alon, and C. D. Bustamante (2004)
Genetics 168, 463-475
   Abstract »    Full Text »    PDF »
The Normal Function of a Speciation Gene, Odysseus, and Its Hybrid Sterility Effect.
S. Sun, C.-T. Ting, and C.-I Wu (2004)
Science 305, 81-83
   Abstract »    Full Text »    PDF »
Genome-Wide Patterns of Expression in Drosophila Pure Species and Hybrid Males.
P. Michalak and M. A. F. Noor (2003)
Mol. Biol. Evol. 20, 1070-1076
   Abstract »    Full Text »    PDF »
A Fine-Scale Genetic Analysis of Hybrid Incompatibilities in Drosophila.
D. C. Presgraves (2003)
Genetics 163, 955-972
   Abstract »    Full Text »    PDF »
Hybrid Sterility, Haldane's Rule and Speciation in Heliconius cydno and H. melpomene.
R. E. Naisbit, C. D. Jiggins, M. Linares, C. Salazar, and J. Mallet (2002)
Genetics 161, 1517-1526
   Abstract »    Full Text »    PDF »
Dominance, Epistasis and the Genetics of Postzygotic Isolation.
M. Turelli and H. A. Orr (2000)
Genetics 154, 1663-1679
   Abstract »    Full Text »
The Drosophila melanogaster Hybrid male rescue Gene Causes Inviability in Male and Female Species Hybrids.
D. A. Barbash, J. Roote, and M. Ashburner (2000)
Genetics 154, 1747-1771
   Abstract »    Full Text »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)