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Science 24 October 1997:
Vol. 278. no. 5338, pp. 602 - 605
DOI: 10.1126/science.278.5338.602
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Predictive Genetic Testing: From Basic Research to Clinical Practice

Neil A. Holtzman, * Patricia D. Murphy, dagger Michael S. Watson, Patricia A. Barr ddagger

As increasing numbers of genes are identified and associated with human diseases, researchers are considering how to bring their discoveries from the research bench to the clinic. Holtzman, Murphy, Watson, and Barr, who were part of a Task Force on Genetic Testing sponsored by the National Institutes of Health and U.S. Department of Energy, discuss policies for regulating the development of genetic tests so that the full potential of gene discovery to help the general population can be realized.

N. A. Holtzman is with the Genetics and Public Policy Studies, Johns Hopkins Medical Institutions, 550 North Broadway, Suite 511, Baltimore, MD 21205, USA. P. D. Murphy is in the Department of Obstetrics and Gynecology, Albany Medical Center, Albany, NY 12208, USA. M. S. Watson is in the Departments of Pediatrics and Genetics, Washington University School of Medicine, St. Louis Children's Hospital, One Children's Place, St. Louis, MO 63110, USA. P. A. Barr is with Barr, Sternberg, and Moss, PC, 507 Main Street, Bennington, VT 05201, USA. N. A. Holtzman was the chair, M. S. Watson was the co-chair, and P. A. Barr and P. D. Murphy were members of the Task Force on Genetic Testing.
*   To whom correspondence should be addressed.

dagger    Consultant to Oncormed, a company that provides genetic tests.

ddagger    Member of the board of the National Breast Cancer Coalition.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)