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Science 6 June 1997:
Vol. 276. no. 5318, pp. 1560 - 1563
DOI: 10.1126/science.276.5318.1560
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Reports

Substantial Genetic Influence on Cognitive Abilities in Twins 80 or More Years Old

Gerald E. McClearn, Boo Johansson, Stig Berg, Nancy L. Pedersen, Frank Ahern, Stephen A. Petrill, Robert Plomin *

General and specific cognitive abilities were studied in intact Swedish same-sex twin pairs 80 or more years old for whom neither twin had major cognitive, sensory, or motor impairment. Resemblance for 110 identical twin pairs significantly exceeded resemblance for 130 fraternal same-sex twin pairs for all abilities. Maximum-likelihood model-fitting estimates of heritability were 62 percent for general cognitive ability, 55 percent for verbal ability, 32 percent for spatial ability, 62 percent for speed of processing, and 52 percent for memory. There was also evidence for the significant influence of idiosyncratic experience as the environmental component that most determines individual differences in cognitive abilities late in life.

G. E. McClearn and F. Ahern, Center for Developmental and Health Genetics, The Pennsylvania State University, University Park, PA 16802, USA.
B. Johansson and S. Berg, Institute for Gerontology, University College of Health Sciences, Jönköping, S-551 11, Sweden.
N. L. Pedersen, Institute for Environmental Medicine, Karolinska Institute, Stockholm, S-17177, Sweden.
S. A. Petrill and R. Plomin, Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK.
*   To whom correspondence should be addressed. E-mail: r.plomin{at}iop.bpmf.ac.uk

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