Related Content
Search Google Scholar for:
More Information
Related Jobs from ScienceCareers
|
|
Science 25 October 1996:
Vol. 274. no. 5287, pp. 597 - 601
DOI: 10.1126/science.274.5287.597
|
|
Reports
Identification of an Asymmetrically Localized Sensor Histidine
Kinase Responsible for Temporally and Spatially Regulated Transcription
James A. Wingrove
and
James W. Gober
*
Caulobacter crescentus undergoes asymmetric cell
division, resulting in a stalked cell and a motile swarmer cell. The
genes encoding external components of the flagellum are expressed in
the swarmer compartment of the predivisional cell through the localized
activation of the transcription factor FlbD. The mechanisms responsible
for the temporal and spatial activation of FlbD were determined through
identification of FlbE, a histidine kinase required for FlbD activity.
FlbE is asymmetrically distributed in the predivisional cell. It is
located at the pole of the stalked compartment and at the site of cell
division in the swarmer compartment. These findings suggest that FlbE
and FlbD are activated in response to a morphological change in the
cell resulting from cell division events.
Department of Chemistry and Biochemistry and the Molecular Biology
Institute, University of California, Los Angeles, CA 90095-1569, USA.
*
To whom correspondence should be addressed.
Read the Full Text
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
- Polar accumulation of the metabolic sensory histidine kinases DcuS and CitA in Escherichia coli.
- P. Scheu, S. Sdorra, Y.-F. Liao, M. Wegner, T. Basche, G. Unden, and W. Erker (2008)
Microbiology
154, 2463-2472
| Abstract »
| Full Text »
| PDF »
- fleQ, the Gene Encoding the Major Flagellar Regulator of Pseudomonas aeruginosa, Is {sigma}70 Dependent and Is Downregulated by Vfr, a Homolog of Escherichia coli Cyclic AMP Receptor Protein.
- N. Dasgupta, E. P. Ferrell, K. J. Kanack, S. E. H. West, and R. Ramphal (2002)
J. Bacteriol.
184, 5240-5250
| Abstract »
| Full Text »
| PDF »
- Polar Flagellar Motility of the Vibrionaceae.
- L. L. McCarter (2001)
Microbiol. Mol. Biol. Rev.
65, 445-462
| Abstract »
| Full Text »
| PDF »
- Polarity in Action: Asymmetric Protein Localization in Bacteria.
- S. R. Lybarger and J. R. Maddock (2001)
J. Bacteriol.
183, 3261-3267
| Full Text »
- New members of the ctrA regulon: the major chemotaxis operon in Caulobacter is CtrA dependent.
- S. E. Jones, N. L. Ferguson, and M. R. K. Alley (2001)
Microbiology
147, 949-958
| Abstract »
| Full Text »
- Molecular Characterization of Two-Component Systems of Helicobacter pylori.
- D. Beier and R. Frank (2000)
J. Bacteriol.
182, 2068-2076
| Abstract »
| Full Text »
- FlbT Couples Flagellum Assembly to Gene Expression in Caulobacter crescentus.
- E. K. Mangan, J. Malakooti, A. Caballero, P. Anderson, B. Ely, and J. W. Gober (1999)
J. Bacteriol.
181, 6160-6170
| Abstract »
| Full Text »
- Regulated Expression of a Highly Conserved Regulatory Gene Cluster Is Necessary for Controlling Photosynthesis Gene Expression in Response to Anaerobiosis in Rhodobacter capsulatus.
- S. Du, J.-L. K. Kouadio, and C. E. Bauer (1999)
J. Bacteriol.
181, 4334-4341
| Abstract »
| Full Text »
- Aberrant Cell Division and Random FtsZ Ring Positioning in Escherichia coli cpxA* Mutants.
- J. Pogliano, J. M. Dong, P. De Wulf, D. Furlong, D. Boyd, R. Losick, K. Pogliano, and E. C. C. Lin (1998)
J. Bacteriol.
180, 3486-3490
| Abstract »
| Full Text »
- A Membrane-Associated Protein, FliX, Is Required for an Early Step in Caulobacter Flagellar Assembly.
- C. D. Mohr, J. K. MacKichan, and L. Shapiro (1998)
J. Bacteriol.
180, 2175-2185
| Abstract »
| Full Text »
- Computational learning reveals coiled coil-like motifs in histidine kinase linker domains.
- M. Singh, B. Berger, P. S. Kim, J. M. Berger, and A. G. Cochran (1998)
PNAS
95, 2738-2743
| Abstract »
| Full Text »
| PDF »
- Cell cycle-dependent transcriptional and proteolytic regulation of FtsZ in Caulobacter.
- A. J. Kelly, M. J. Sackett, N. Din, E. Quardokus, and Y. V. Brun (1998)
Genes & Dev.
12, 880-893
| Abstract »
| Full Text »
- Protein Localization and Cell Fate in Bacteria.
- L. Shapiro and R. Losick (1997)
Science
276, 712-718
| Abstract »
| Full Text »
|
|
