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Science 29 March 1996:
Vol. 271. no. 5257, pp. 1848 - 1851
DOI: 10.1126/science.271.5257.1848
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Reports

Enhancement of Solution NMR and MRI with Laser-Polarized Xenon

G. Navon, * Y.-Q. Song, T. Rõõm, S. Appelt, R. E. Taylor, A. Pines dagger

Optical pumping with laser light can be used to polarize the nuclear spins of gaseous xenon-129. When hyperpolarized xenon-129 is dissolved in liquids, a time-dependent departure of the proton spin polarization from its thermal equilibrium is observed. The variation of the magnetization is an unexpected manifestation of the nuclear Overhauser effect, a consequence of cross-relaxation between the spins of solution protons and dissolved xenon-129. Time-resolved magnetic resonance images of both nuclei in solution show that the proton magnetization is selectively perturbed in regions containing spin-polarized xenon-129. This effect could find use in nuclear magnetic resonance spectroscopy of surfaces and proteins and in magnetic resonance imaging.

Materials Sciences Division, Lawrence Berkeley National Laboratory, and Department of Chemistry, University of California, Berkeley, CA 94720, USA.
* Permanent address: School of Chemistry, Tel Aviv University, Tel Aviv 69978, Israel.
dagger To whom correspondence should be addressed at the Department of Chemistry, University of California, Berkeley, CA 94720, USA.


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