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Science 29 March 1996:
Vol. 271. no. 5257, pp. 1848 - 1851
DOI: 10.1126/science.271.5257.1848
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Reports
Enhancement of Solution NMR and MRI with Laser-Polarized Xenon
G. Navon,
*
Y.-Q. Song,
T. Rõõm,
S. Appelt,
R. E. Taylor,
A. Pines
Optical pumping with laser light can be used to polarize the
nuclear spins of gaseous xenon-129. When hyperpolarized xenon-129 is
dissolved in liquids, a time-dependent departure of the proton spin
polarization from its thermal equilibrium is observed. The variation of
the magnetization is an unexpected manifestation of the nuclear
Overhauser effect, a consequence of cross-relaxation between the spins
of solution protons and dissolved xenon-129. Time-resolved magnetic
resonance images of both nuclei in solution show that the proton
magnetization is selectively perturbed in regions containing
spin-polarized xenon-129. This effect could find use in nuclear
magnetic resonance spectroscopy of surfaces and proteins and in
magnetic resonance imaging.
Materials Sciences Division, Lawrence Berkeley National
Laboratory, and Department of Chemistry, University of California,
Berkeley, CA 94720, USA.
*
Permanent address: School of Chemistry, Tel Aviv University, Tel
Aviv 69978, Israel.
To whom correspondence should be addressed at the Department
of Chemistry, University of California, Berkeley, CA 94720, USA.
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