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Science 22 September 1995:
Vol. 269. no. 5231, pp. 1709 - 1711
DOI: 10.1126/science.7569897
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Articles

Science, Vol 269, Issue 5231, 1709-1711
Copyright © 1995 by American Association for the Advancement of Science

articles

Mating patterns in malaria parasite populations of Papua New Guinea

RE Paul, MJ Packer, M Walmsley, M Lagog, LC Ranford-Cartwright, R Paru, and KP Day

Department of Zoology, University of Oxford, UK.

Description of the genetic structure of malaria parasite populations is central to an understanding of the spread of multiple-locus drug and vaccine resistance. The Plasmodium falciparum mating patterns from madang, Papua New Guinea, where intense transmission of malaria occurs, are described here. A high degree of inbreeding occurs in the absence of detectable linkage disequilibrium. This contrasts with other studies, indicating that the genetic structure of malaria parasite populations is neither clonal nor panmictic but will vary according to the transmission characteristics of the region.


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