Science 8 September 1995: Vol. 269. no. 5229, pp. 1429 - 1431 DOI: 10.1126/science.7660126

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Articles

Interaction of APC/C-E3 Ligase with Swi6/HP1 and Clr4/Suv39 in Heterochromatin Assembly in Fission Yeast.

R. N. Dubey, N. Nakwal, K. K. Bisht, A. Saini, S. Haldar, and J. Singh (2009)
J. Biol. Chem. 284, 7165-7176
 |  Abstract »  |  Full Text »  |  PDF »

Balance between Distinct HP1 Family Proteins Controls Heterochromatin Assembly in Fission Yeast.

M. Sadaie, R. Kawaguchi, Y. Ohtani, F. Arisaka, K. Tanaka, K. Shirahige, and J.-i. Nakayama (2008)
Mol. Cell. Biol. 28, 6973-6988
 |  Abstract »  |  Full Text »  |  PDF »

Fission yeast chromatin assembly factor 1 assists in the replication-coupled maintenance of heterochromatin.

K. Dohke, S. Miyazaki, K. Tanaka, T. Urano, S. I. S. Grewal, and Y. Murakami (2008)
Genes Cells 13, 1027-1043
 |  Abstract »  |  Full Text »  |  PDF »

Msc1 Acts Through Histone H2A.Z to Promote Chromosome Stability in Schizosaccharomyces pombe.

S. Ahmed, B. Dul, X. Qiu, and N. C. Walworth (2007)
Genetics 177, 1487-1497
 |  Abstract »  |  Full Text »  |  PDF »

The Clr4 methyltransferase determines the subnuclear localization of the mating-type region in fission yeast.

J. Alfredsson-Timmins, F. Henningson, and P. Bjerling (2007)
J. Cell Sci. 120, 1935-1943
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of Epe1 With the Heterochromatin Assembly Pathway in Schizosaccharomyces pombe.

S. Isaac, J. Walfridsson, T. Zohar, D. Lazar, T. Kahan, K. Ekwall, and A. Cohen (2007)
Genetics 175, 1549-1560
 |  Abstract »  |  Full Text »  |  PDF »

Epigenetic regulation of facultative heterochromatinisation in Planococcus citri via the Me(3)K9H3-HP1-Me(3)K20H4 pathway.

S. Bongiorni, B. Pasqualini, M. Taranta, P. B. Singh, and G. Prantera (2007)
J. Cell Sci. 120, 1072-1080
 |  Abstract »  |  Full Text »  |  PDF »

The fission yeast DASH complex is essential for satisfying the spindle assembly checkpoint induced by defects in the inner-kinetochore proteins.

Y. Kobayashi, S. Saitoh, Y. Ogiyama, S. Soejima, and K. Takahashi (2007)
Genes Cells 12, 311-328
 |  Abstract »  |  Full Text »  |  PDF »

HP1 Binding to Chromatin Methylated at H3K9 Is Enhanced by Auxiliary Factors.

R. Eskeland, A. Eberharter, and A. Imhof (2007)
Mol. Cell. Biol. 27, 453-465
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: UV irradiation induces a postreplication DNA damage checkpoint.

A. J. Callegari and T. J. Kelly (2006)
PNAS 103, 15877-15882
 |  Abstract »  |  Full Text »  |  PDF »

A Requirement for Dimerization of HP1Hs{alpha} in Suppression of Breast Cancer Invasion.

L. E. Norwood, T. J. Moss, N. V. Margaryan, S. L. Cook, L. Wright, E. A. Seftor, M. J. C. Hendrix, D. A. Kirschmann, and L. L. Wallrath (2006)
J. Biol. Chem. 281, 18668-18676
 |  Abstract »  |  Full Text »  |  PDF »

Differential Effects of Heterochromatin Protein 1 Isoforms on Mitotic Chromosome Distribution and Growth in Dictyostelium discoideum.

M. Kaller, U. Euteneuer, and W. Nellen (2006)
Eukaryot. Cell 5, 530-543
 |  Abstract »  |  Full Text »  |  PDF »

The Clr7 and Clr8 Directionality Factors and the Pcu4 Cullin Mediate Heterochromatin Formation in the Fission Yeast Schizosaccharomyces pombe.

G. Thon, K. R. Hansen, S. P. Altes, D. Sidhu, G. Singh, J. Verhein-Hansen, M. J. Bonaduce, and A. J. S. Klar (2005)
Genetics 171, 1583-1595
 |  Abstract »  |  Full Text »  |  PDF »

Schizosaccharomyces pombe mst2+ Encodes a MYST Family Histone Acetyltransferase That Negatively Regulates Telomere Silencing.

E. B. Gomez, J. M. Espinosa, and S. L. Forsburg (2005)
Mol. Cell. Biol. 25, 8887-8903
 |  Abstract »  |  Full Text »  |  PDF »

RNA meets chromatin.

E. Bernstein and C. D. Allis (2005)
Genes & Dev. 19, 1635-1655
 |  Abstract »  |  Full Text »  |  PDF »

The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres.

J. Walfridsson, P. Bjerling, M. Thalen, E.-J. Yoo, S. D. Park, and K. Ekwall (2005)
Nucleic Acids Res. 33, 2868-2879
 |  Abstract »  |  Full Text »  |  PDF »

HP1 modulates the transcription of cell-cycle regulators in Drosophila melanogaster.

F. De Lucia, J.-Q. Ni, C. Vaillant, and F.-L. Sun (2005)
Nucleic Acids Res. 33, 2852-2858
 |  Abstract »  |  Full Text »  |  PDF »

The role of heterochromatin in centromere function.

A. L Pidoux and R. C Allshire (2005)
Phil Trans R Soc B 360, 569-579
 |  Abstract »  |  Full Text »  |  PDF »

RNA Interference (RNAi)-Dependent and RNAi-Independent Association of the Chp1 Chromodomain Protein with Distinct Heterochromatic Loci in Fission Yeast.

V. J. Petrie, J. D. Wuitschick, C. D. Givens, A. M. Kosinski, and J. F. Partridge (2005)
Mol. Cell. Biol. 25, 2331-2346
 |  Abstract »  |  Full Text »  |  PDF »

Conserved Locus-Specific Silencing Functions of Schizosaccharomyces pombe sir2+.

L. L. Freeman-Cook, E. B. Gomez, E. J. Spedale, J. Marlett, S. L. Forsburg, L. Pillus, and P. Laurenson (2005)
Genetics 169, 1243-1260
 |  Abstract »  |  Full Text »  |  PDF »

The Fission Yeast Kinetochore Component Spc7 Associates with the EB1 Family Member Mal3 and Is Required for Kinetochore-Spindle Association.

A. Kerres, C. Vietmeier-Decker, J. Ortiz, I. Karig, C. Beuter, J. Hegemann, J. Lechner, and U. Fleig (2004)
Mol. Biol. Cell 15, 5255-5267
 |  Abstract »  |  Full Text »  |  PDF »

A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe.

P. Bjerling, K. Ekwall, R. Egel, and G. Thon (2004)
Nucleic Acids Res. 32, 4421-4428
 |  Abstract »  |  Full Text »  |  PDF »

Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect.

S. R. Oikemus, N. McGinnis, J. Queiroz-Machado, H. Tukachinsky, S. Takada, C. E. Sunkel, and M. H. Brodsky (2004)
Genes & Dev. 18, 1850-1861
 |  Abstract »  |  Full Text »  |  PDF »

High- and Low-mobility Populations of HP1 in Heterochromatin of Mammalian Cells.

L. Schmiedeberg, K. Weisshart, S. Diekmann, G. Meyer zu Hoerste, and P. Hemmerich (2004)
Mol. Biol. Cell 15, 2819-2833
 |  Abstract »  |  Full Text »  |  PDF »

The Schizosaccharomyces pombe HIRA-Like Protein Hip1 Is Required for the Periodic Expression of Histone Genes and Contributes to the Function of Complex Centromeres.

C. Blackwell, K. A. Martin, A. Greenall, A. Pidoux, R. C. Allshire, and S. K. Whitehall (2004)
Mol. Cell. Biol. 24, 4309-4320
 |  Abstract »  |  Full Text »  |  PDF »

Histone H3 lysine 9 methylation is required for DNA elimination in developing macronuclei in Tetrahymena.

Y. Liu, K. Mochizuki, and M. A. Gorovsky (2004)
PNAS 101, 1679-1684
 |  Abstract »  |  Full Text »  |  PDF »

Fission yeast Arp6 is required for telomere silencing, but functions independently of Swi6.

M. Ueno, T. Murase, T. Kibe, N. Ohashi, K. Tomita, Y. Murakami, M. Uritani, T. Ushimaru, and M. Harata (2004)
Nucleic Acids Res. 32, 736-741
 |  Abstract »  |  Full Text »  |  PDF »

RNA Interference, Heterochromatin, and Centromere Function.

R.C. ALLSHIRE (2004)
Cold Spring Harb Symp Quant Biol 69, 389-396
 |  Abstract »  |  PDF »

Distinct centromere domain structures with separate functions demonstrated in live fission yeast cells.

H. Appelgren, B. Kniola, and K. Ekwall (2003)
J. Cell Sci. 116, 4035-4042
 |  Abstract »  |  Full Text »  |  PDF »

Stable inheritance of telomere chromatin structure and function in the absence of telomeric repeats.

M. Sadaie, T. Naito, and F. Ishikawa (2003)
Genes & Dev. 17, 2271-2282
 |  Abstract »  |  Full Text »  |  PDF »

Sim4: a novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation.

A. L. Pidoux, W. Richardson, and R. C. Allshire (2003)
J. Cell Biol. 161, 295-307
 |  Abstract »  |  Full Text »  |  PDF »

Early-replicating heterochromatin.

S.-M. Kim, D. D. Dubey, and J. A. Huberman (2003)
Genes & Dev. 17, 330-335
 |  Abstract »  |  Full Text »  |  PDF »

Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway.

G. Goshima, T. Kiyomitsu, K. Yoda, and M. Yanagida (2003)
J. Cell Biol. 160, 25-39
 |  Abstract »  |  Full Text »  |  PDF »

Dicer is required for chromosome segregation and gene silencing in fission yeast cells.

P. Provost, R. A. Silverstein, D. Dishart, J. Walfridsson, I. Djupedal, B. Kniola, A. Wright, B. Samuelsson, O. Radmark, and K. Ekwall (2002)
PNAS 99, 16648-16653
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of a Schizosaccharomyces pombe Strain Deleted for a Sequence Homologue of the Human Damaged DNA Binding 1 (DDB1) Gene.

F. Zolezzi, J. Fuss, S. Uzawa, and S. Linn (2002)
J. Biol. Chem. 277, 41183-41191
 |  Abstract »  |  Full Text »  |  PDF »

The Mal2p Protein Is an Essential Component of the Fission Yeast Centromere.

Q.-W. Jin, A. L. Pidoux, C. Decker, R. C. Allshire, and U. Fleig (2002)
Mol. Cell. Biol. 22, 7168-7183
 |  Abstract »  |  Full Text »  |  PDF »

Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications.

H. Nakagawa, J.-K. Lee, J. Hurwitz, R. C. Allshire, J.-i. Nakayama, S. I.S. Grewal, K. Tanaka, and Y. Murakami (2002)
Genes & Dev. 16, 1766-1778
 |  Abstract »  |  Full Text »  |  PDF »

Expression-State Boundaries in the Mating-Type Region of Fission Yeast.

G. Thon, P. Bjerling, C. M. Bunner, and J. Verhein-Hansen (2002)
Genetics 161, 611-622
 |  Abstract »  |  Full Text »  |  PDF »

Fission Yeast Mad3p Is Required for Mad2p To Inhibit the Anaphase-Promoting Complex and Localizes to Kinetochores in a Bub1p-, Bub3p-, and Mph1p-Dependent Manner.

D. N. Millband and K. G. Hardwick (2002)
Mol. Cell. Biol. 22, 2728-2742
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional silencing in Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Y. Huang (2002)
Nucleic Acids Res. 30, 1465-1482
 |  Abstract »  |  Full Text »  |  PDF »

Conserved Wat1/Pop3 WD-repeat protein of fission yeast secures genome stability through microtubule integrity and may be involved in mRNA maturation.

I. L. Ochotorena, D. Hirata, K.-i. Kominami, J. Potashkin, F. Sahin, K. Wentz-Hunter, K. L. Gould, K. Sato, Y. Yoshida, L. Vardy, et al. (2002)
J. Cell Sci. 114, 2911-2920
 |  Abstract »  |  Full Text »  |  PDF »

Fission Yeast Mutants Affecting Telomere Clustering and Meiosis-Specific Spindle Pole Body Integrity.

Y. Jin, S. Uzawa, and W. Z. Cande (2002)
Genetics 160, 861-876
 |  Abstract »  |  Full Text »  |  PDF »

Modifiers of Terminal Deficiency-Associated Position Effect Variegation in Drosophila.

K. M. Donaldson, A. Lui, and G. H. Karpen (2002)
Genetics 160, 995-1009
 |  Abstract »  |  Full Text »  |  PDF »

Schizosaccharomyces pombe Bir1p, a Nuclear Protein That Localizes to Kinetochores and the Spindle Midzone, Is Essential for Chromosome Condensation and Spindle Elongation During Mitosis.

S. Rajagopalan and M. K. Balasubramanian (2002)
Genetics 160, 445-456
 |  Abstract »  |  Full Text »  |  PDF »

Fission Yeast F-box Protein Pof3 Is Required for Genome Integrity and Telomere Function.

S. Katayama, K. Kitamura, A. Lehmann, O. Nikaido, and T. Toda (2002)
Mol. Biol. Cell 13, 211-224
 |  Abstract »  |  Full Text »  |  PDF »

The Domain Structure of Centromeres Is Conserved from Fission Yeast to Humans.

B. Kniola, E. O'Toole, J. R. McIntosh, B. Mellone, R. Allshire, S. Mengarelli, K. Hultenby, and K. Ekwall (2001)
Mol. Biol. Cell 12, 2767-2775
 |  Abstract »  |  Full Text »  |  PDF »

Functional Redundancies, Distinct Localizations and Interactions Among Three Fission Yeast Homologs of Centromere Protein-B.

J. T. Irelan, G. I. Gutkin, and L. Clarke (2001)
Genetics 157, 1191-1203
 |  Abstract »  |  Full Text »

The Polar Arrangement of Telomeres in Interphase and Meiosis. Rabl Organization and the Bouquet.

C. R. Cowan, P. M. Carlton, and W. Z. Cande (2001)
Plant Physiology 125, 532-538
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The Ndc80p Complex from Saccharomyces cerevisiae Contains Conserved Centromere Components and Has a Function in Chromosome Segregation.

P. A. Wigge and J. V. Kilmartin (2001)
J. Cell Biol. 152, 349-360
 |  Abstract »  |  Full Text »  |  PDF »

Conservation of Heterochromatin Protein 1 Function.

G. Wang, A. Ma, C.-m. Chow, D. Horsley, N. R. Brown, I. G. Cowell, and P. B. Singh (2000)
Mol. Cell. Biol. 20, 6970-6983
 |  Abstract »  |  Full Text »  |  PDF »

Four Chromo-domain Proteins of Schizosaccharomyces pombe Differentially Repress Transcription at Various Chromosomal Locations.

G. Thon and J. Verhein-Hansen (2000)
Genetics 155, 551-568
 |  Abstract »  |  Full Text »

Fission yeast Hrp1, a chromodomain ATPase, is required for proper chromosome segregation and its overexpression interferes with chromatin condensation.

E. J. Yoo, Y. H. Jin, Y. K. Jang, P. Bjerling, M. Tabish, S. H. Hong, K. Ekwall, and S. D. Park (2000)
Nucleic Acids Res. 28, 2004-2011
 |  Abstract »  |  Full Text »  |  PDF »

Distinct protein interaction domains and protein spreading in a complex centromere.

J. F. Partridge, B. Borgstrøm, and R. C. Allshire (2000)
Genes & Dev. 14, 783-791
 |  Abstract »  |  Full Text »

Cell cycle-dependent phosphorylation of the ATRX protein correlates with changes in nuclear matrix and chromatin association.

N. G. Berube, C. A. Smeenk, and D. J. Picketts (2000)
Hum. Mol. Genet. 9, 539-547
 |  Abstract »  |  Full Text »  |  PDF »

Live analysis of lagging chromosomes during anaphase and their effect on spindle elongation rate in fission yeast.

A. Pidoux, S Uzawa, P. Perry, W. Cande, and R. Allshire (2000)
J. Cell Sci. 113, 4177-4191
 |  Abstract »  |  PDF »

Fission Yeast Mutants That Alleviate Transcriptional Silencing in Centromeric Flanking Repeats and Disrupt Chromosome Segregation.

K. Ekwall, G. Cranston, and R. C. Allshire (1999)
Genetics 153, 1153-1169
 |  Abstract »  |  Full Text »

The Schizosaccharomyces pombe hst4+ Gene Is a SIR2 Homologue with Silencing and Centromeric Functions.

L. L. Freeman-Cook, J. M. Sherman, C. B. Brachmann, R. C. Allshire, J. D. Boeke, and L. Pillus (1999)
Mol. Biol. Cell 10, 3171-3186
 |  Abstract »  |  Full Text »

Defects in Components of the Proteasome Enhance Transcriptional Silencing at Fission Yeast Centromeres and Impair Chromosome Segregation.

J.-P. Javerzat, G. McGurk, G. Cranston, C. Barreau, P. Bernard, C. Gordon, and R. Allshire (1999)
Mol. Cell. Biol. 19, 5155-5165
 |  Abstract »  |  Full Text »  |  PDF »

Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation.

G. Goshima, S. Saitoh, and M. Yanagida (1999)
Genes & Dev. 13, 1664-1677
 |  Abstract »  |  Full Text »

Transcriptional Repression by XPc1, a New Polycomb Homolog in Xenopus laevis Embryos, Is Independent of Histone Deacetylase.

J. Strouboulis, S. Damjanovski, D. Vermaak, F. Meric, and A. P. Wolffe (1999)
Mol. Cell. Biol. 19, 3958-3968
 |  Abstract »  |  Full Text »  |  PDF »

Position Effect Variegation at the Mating-Type Locus of Fission Yeast: A cis-Acting Element Inhibits Covariegated Expression of Genes in the Silent and Expressed Domains.

N. Ayoub, I. Goldshmidt, and A. Cohen (1999)
Genetics 152, 495-508
 |  Abstract »  |  Full Text »

A Nonessential HP1-Like Protein Affects Starvation-Induced Assembly of Condensed Chromatin and Gene Expression in Macronuclei of Tetrahymena thermophila.

H. Huang, J. F. Smothers, E. A. Wiley, and C. D. Allis (1999)
Mol. Cell. Biol. 19, 3624-3634
 |  Abstract »  |  Full Text »  |  PDF »

A New Member of the Sin3 Family of Corepressors Is Essential for Cell Viability and Required for Retroelement Propagation in Fission Yeast.

V. D. Dang, M. J. Benedik, K. Ekwall, J. Choi, R. C. Allshire, and H. L. Levin (1999)
Mol. Cell. Biol. 19, 2351-2365
 |  Abstract »  |  Full Text »  |  PDF »

Reduced dosage of a single fission yeast MCM protein causes genetic instability and S phase delay.

D. Liang, J. Hodson, and S. Forsburg (1999)
J. Cell Sci. 112, 559-567
 |  Abstract »  |  PDF »

Fission Yeast Bub1 Is a Mitotic Centromere Protein Essential for the Spindle Checkpoint and the Preservation of Correct Ploidy through Mitosis.

P. Bernard, K. Hardwick, and J.-P. Javerzat (1998)
J. Cell Biol. 143, 1775-1787
 |  Abstract »  |  Full Text »  |  PDF »

An HP1-like protein is missing from transcriptionally silent micronuclei of Tetrahymena.

H. Huang, E. A. Wiley, C. R. Lending, and C. D. Allis (1998)
PNAS 95, 13624-13629
 |  Abstract »  |  Full Text »  |  PDF »

Histone Deacetylase Homologs Regulate Epigenetic Inheritance of Transcriptional Silencing and Chromosome Segregation in Fission Yeast.

S. I. S. Grewal, M. J. Bonaduce, and A. J. S. Klar (1998)
Genetics 150, 563-576
 |  Abstract »  |  Full Text »

The fission yeast microtubule cytoskeleton.

I. Hagan (1998)
J. Cell Sci. 111, 1603-1612
 |  Abstract »  |  PDF »

Purification and characterization of a CENP-B homologue protein that binds to the centromeric K-type repeat DNA of Schizosaccharomyces pombe.

J.-K. Lee, J. A. Huberman, and J. Hurwitz (1997)
PNAS 94, 8427-8432
 |  Abstract »  |  Full Text »  |  PDF »

A Centromere DNA-binding Protein from Fission Yeast Affects Chromosome Segregation and Has Homology to Human CENP-B.

D. Halverson, M. Baum, J. Stryker, J. Carbon, and L. Clarke (1997)
J. Cell Biol. 136, 487-500
 |  Abstract »  |  Full Text »  |  PDF »

Interaction between an Integral Protein of the Nuclear Envelope Inner Membrane and Human Chromodomain Proteins Homologous to Drosophila HP1.

Q. Ye and H. J. Worman (1996)
J. Biol. Chem. 271, 14653-14656
 |  Abstract »  |  Full Text »  |  PDF »

Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function.

K Ekwall, E. Nimmo, J. Javerzat, B Borgstrom, R Egel, G Cranston, and R Allshire (1996)
J. Cell Sci. 109, 2637-2648
 |  Abstract »  |  PDF »

The Centromere: Hub of Chromosomal Activities.

A. F. Pluta, A. M. Mackay, A. M. Ainsztein, I. G. Goldberg, and W. C. Earnshaw (1995)
Science 270, 1591-1594
 |  Abstract »  |  PDF »

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