Science 25 August 1995: Vol. 269. no. 5227, pp. 1108 - 1112 DOI: 10.1126/science.7652557

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Articles

Comparative analysis of fatty acid-binding protein 4 promoters: Conservation of peroxisome proliferator-activated receptor binding sites.

J. Shin, B. Li, M. E. Davis, Y. Suh, and K. Lee (2009)
J Anim Sci 87, 3923-3934
 |  Abstract »  |  Full Text »  |  PDF »

Mouse models of inherited lipodystrophy.

D. B. Savage (2009)
Dis. Model. Mech. 2, 554-562
 |  Abstract »  |  Full Text »  |  PDF »

Aspects of the Control of Phosphoenolpyruvate Carboxykinase Gene Transcription.

J. Yang, L. Reshef, H. Cassuto, G. Aleman, and R. W. Hanson (2009)
J. Biol. Chem. 284, 27031-27035
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Adult-onset degeneration of adipose tissue in mice deficient for the Sox8 transcription factor.

S. I. E. Guth, K. Schmidt, A. Hess, and M. Wegner (2009)
J. Lipid Res. 50, 1269-1280
 |  Abstract »  |  Full Text »  |  PDF »

FIP1L1-PDGFR{alpha} Imposes Eosinophil Lineage Commitment on Hematopoietic Stem/Progenitor Cells.

K. Fukushima, I. Matsumura, S. Ezoe, M. Tokunaga, M. Yasumi, Y. Satoh, H. Shibayama, H. Tanaka, A. Iwama, and Y. Kanakura (2009)
J. Biol. Chem. 284, 7719-7732
 |  Abstract »  |  Full Text »  |  PDF »

Identification of three loci affecting HDL-cholesterol levels in a screen for chemically induced recessive mutations in mice.

T. Juan, M. M. Veniant, J. Helmering, P. Babij, D. M. Baker, M. A. Damore, M. B. Bass, T. Gyuris, M. Chhoa, C.-M. Li, et al. (2009)
J. Lipid Res. 50, 534-545
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-Stimulated Gene ISG12b1 Inhibits Adipogenic Differentiation and Mitochondrial Biogenesis in 3T3-L1 Cells.

B. Li, J. Shin, and K. Lee (2009)
Endocrinology 150, 1217-1224
 |  Abstract »  |  Full Text »  |  PDF »

Dysregulation of the C/EBP{alpha} Differentiation Pathway in Human Cancer.

S. Koschmieder, B. Halmos, E. Levantini, and D. G. Tenen (2009)
J. Clin. Oncol. 27, 619-628
 |  Abstract »  |  Full Text »  |  PDF »

Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function and Human Diseases.

B. Turgeon and S. Meloche (2009)
Physiol Rev 89, 1-26
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CCAAT/Enhancer Binding Protein {alpha} (C/EBP{alpha}) in Adipose Tissue Regulates Genes in Lipid and Glucose Metabolism and a Genetic Variation in C/EBP{alpha} Is Associated with Serum Levels of Triglycerides.

L. E. Olofsson, M. Orho-Melander, L. William-Olsson, K. Sjoholm, L. Sjostrom, L. Groop, B. Carlsson, L. M. S. Carlsson, and B. Olsson (2008)
J. Clin. Endocrinol. Metab. 93, 4880-4886
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of CCAAT/Enhancer-binding Protein {alpha} Regulates GLUT4 Expression and Glucose Transport in Adipocytes.

H. C. Cha, N. R. Oak, S. Kang, T.-A. Tran, S. Kobayashi, S.-H. Chiang, D. G. Tenen, and O. A. MacDougald (2008)
J. Biol. Chem. 283, 18002-18011
 |  Abstract »  |  Full Text »  |  PDF »

Liver-Specific Hepatocyte Nuclear Factor-4{alpha} Deficiency: Greater Impact on Gene Expression in Male than in Female Mouse Liver.

M. G. Holloway, G. D. Miles, A. A. Dombkowski, and D. J. Waxman (2008)
Mol. Endocrinol. 22, 1274-1286
 |  Abstract »  |  Full Text »  |  PDF »

Hypoxia Down-regulates CCAAT/Enhancer Binding Protein-{alpha} Expression in Breast Cancer Cells.

R. Seifeddine, A. Dreiem, E. Blanc, M.-C. Fulchignoni-Lataud, M.-A. L. F. Belda, F. Lecuru, T. H. Mayi, N. Mazure, V. Favaudon, C. Massaad, et al. (2008)
Cancer Res. 68, 2158-2165
 |  Abstract »  |  Full Text »  |  PDF »

Melanocortin 2 receptor is required for adrenal gland development, steroidogenesis, and neonatal gluconeogenesis.

D. Chida, S. Nakagawa, S. Nagai, H. Sagara, H. Katsumata, T. Imaki, H. Suzuki, F. Mitani, T. Ogishima, C. Shimizu, et al. (2007)
PNAS 104, 18205-18210
 |  Abstract »  |  Full Text »  |  PDF »

An Intronic Locus Control Region Plays an Essential Role in the Establishment of an Autonomous Hepatic Chromatin Domain for the Human Vitamin D-Binding Protein Gene.

T. Hiroki, S. A. Liebhaber, and N. E. Cooke (2007)
Mol. Cell. Biol. 27, 7365-7380
 |  Abstract »  |  Full Text »  |  PDF »

CCAAT/Enhancer-binding Protein {delta} (C/EBP{delta}) Maintains Amelogenin Expression in the Absence of C/EBP{alpha} in Vivo.

Y. Xu, Y. L. Zhou, F. J. Gonzalez, and M. L. Snead (2007)
J. Biol. Chem. 282, 29882-29889
 |  Abstract »  |  Full Text »  |  PDF »

Excess Weight Gain during the Early Postnatal Period Is Associated with Permanent Reprogramming of Brown Adipose Tissue Adaptive Thermogenesis.

X. Q. Xiao, S. M. Williams, B. E. Grayson, M. M. Glavas, M. A. Cowley, M. S. Smith, and K. L. Grove (2007)
Endocrinology 148, 4150-4159
 |  Abstract »  |  Full Text »  |  PDF »

TRB2, a Mouse Tribbles Ortholog, Suppresses Adipocyte Differentiation by Inhibiting AKT and C/EBPbeta.

T. Naiki, E. Saijou, Y. Miyaoka, K. Sekine, and A. Miyajima (2007)
J. Biol. Chem. 282, 24075-24082
 |  Abstract »  |  Full Text »  |  PDF »

Sequential Regulation of Diacylglycerol Acyltransferase 2 Expression by CAAT/Enhancer-binding Protein beta (C/EBPbeta) and C/EBP{alpha} during Adipogenesis.

V. A. Payne, W.-S. Au, S. L. Gray, E. D. Nora, S. M. Rahman, R. Sanders, D. Hadaschik, J. E. Friedman, S. O'Rahilly, and J. J. Rochford (2007)
J. Biol. Chem. 282, 21005-21014
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Ablation of CCAAT/Enhancer Binding Protein {alpha} in Epidermis Reveals Its Role in Suppression of Epithelial Tumorigenesis.

K. D. Loomis, S. Zhu, K. Yoon, P. F. Johnson, and R. C. Smart (2007)
Cancer Res. 67, 6768-6776
 |  Abstract »  |  Full Text »  |  PDF »

Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.

R. T. Sasmono, A. Ehrnsperger, S. L. Cronau, T. Ravasi, R. Kandane, M. J. Hickey, A. D. Cook, S. R. Himes, J. A. Hamilton, and D. A. Hume (2007)
J. Leukoc. Biol. 82, 111-123
 |  Abstract »  |  Full Text »  |  PDF »

Differences in regulation of type I collagen synthesis in primary and passaged hepatic stellate cell cultures: the role of {alpha}5beta1-integrin.

M. Dodig, B. Ogunwale, S. Dasarathy, M. Li, B. Wang, and A. J. McCullough (2007)
Am J Physiol Gastrointest Liver Physiol 293, G154-G164
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CCAAT/Enhancer-binding Protein beta Deletion Reduces Adiposity, Hepatic Steatosis, and Diabetes in Leprdb/db Mice.

J. M. Schroeder-Gloeckler, S. M. Rahman, R. C. Janssen, L. Qiao, J. Shao, M. Roper, S. J. Fischer, E. Lowe, D. J. Orlicky, J. L. McManaman, et al. (2007)
J. Biol. Chem. 282, 15717-15729
 |  Abstract »  |  Full Text »  |  PDF »

Mammalian Target of Rapamycin Activation Impairs Hepatocytic Differentiation and Targets Genes Moderating Lipid Homeostasis and Hepatocellular Growth.

R. Parent, D. Kolippakkam, G. Booth, and L. Beretta (2007)
Cancer Res. 67, 4337-4345
 |  Abstract »  |  Full Text »  |  PDF »

Dysregulation of C/EBP{alpha} by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease.

M.-C. Chiang, H.-M. Chen, Y.-H. Lee, H.-H. Chang, Y.-C. Wu, B.-W. Soong, C.-M. Chen, Y.-R. Wu, C.-S. Liu, D.-M. Niu, et al. (2007)
Hum. Mol. Genet. 16, 483-498
 |  Abstract »  |  Full Text »  |  PDF »

The -20 and -217 Promoter Variants Dominate Differential Angiotensinogen Haplotype Regulation in Angiotensinogen-Expressing Cells.

M. E. Dickson, M. B. Zimmerman, K. Rahmouni, and C. D. Sigmund (2007)
Hypertension 49, 631-639
 |  Abstract »  |  Full Text »  |  PDF »

Orphan Nuclear Receptor Nur77 Accelerates the Initial Phase of Adipocyte Differentiation in 3T3-L1 Cells by Promoting Mitotic Clonal Expansion.

T. Fumoto, T. Yamaguchi, F. Hirose, and T. Osumi (2007)
J. Biochem. 141, 181-192
 |  Abstract »  |  Full Text »  |  PDF »

Mice With a Deletion in the Gene for CCAAT/Enhancer-Binding Protein {beta} Are Protected Against Diet-Induced Obesity.

C. A. Millward, J. D. Heaney, D. S. Sinasac, E. C. Chu, I. R. Bederman, D. A. Gilge, S. F. Previs, and C. M. Croniger (2007)
Diabetes 56, 161-167
 |  Abstract »  |  Full Text »  |  PDF »

Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program.

J.-F. Louet, A. Coste, L. Amazit, M. Tannour-Louet, R.-C. Wu, S. Y. Tsai, M.-J. Tsai, J. Auwerx, and B. W. O'Malley (2006)
PNAS 103, 17868-17873
 |  Abstract »  |  Full Text »  |  PDF »

Type II nuclear hormone receptors, coactivator, and target gene repression in adipose tissue in the acute-phase response.

B. Lu, A. H. Moser, J. K. Shigenaga, K. R. Feingold, and C. Grunfeld (2006)
J. Lipid Res. 47, 2179-2190
 |  Abstract »  |  Full Text »  |  PDF »

Ectopic expression of C/EBP{alpha} in the lung epithelium disrupts late lung development.

T. Berg, L. Didon, and M. Nord (2006)
Am J Physiol Lung Cell Mol Physiol 291, L683-L693
 |  Abstract »  |  Full Text »  |  PDF »

CCAAT/Enhancer-binding Protein {alpha} Mediates Induction of Hepatic Phosphoenolpyruvate Carboxykinase by p38 Mitogen-activated Protein Kinase.

L. Qiao, O. A. MacDougald, and J. Shao (2006)
J. Biol. Chem. 281, 24390-24397
 |  Abstract »  |  Full Text »  |  PDF »

Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is potently suppressed by C/EBP{alpha}.

G. Ferrari-Amorotti, K. Keeshan, M. Zattoni, C. Guerzoni, G. Iotti, S. Cattelani, N. J. Donato, and B. Calabretta (2006)
Blood 108, 1353-1362
 |  Abstract »  |  Full Text »  |  PDF »

Knocking Down Liver CCAAT/Enhancer-Binding Protein {alpha} by Adenovirus-Transduced Silent Interfering Ribonucleic Acid Improves Hepatic Gluconeogenesis and Lipid Homeostasis in db/db Mice.

L. Qiao, P. S. MacLean, H. You, J. Schaack, and J. Shao (2006)
Endocrinology 147, 3060-3069
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Promoter for the 11{beta}-Hydroxysteroid Dehydrogenase Type 1 Gene Is Active in Lung and Is C/EBP{alpha} Independent.

C. Bruley, V. Lyons, A. G. F. Worsley, M. D. Wilde, G. D. Darlington, N. M. Morton, J. R. Seckl, and K. E. Chapman (2006)
Endocrinology 147, 2879-2885
 |  Abstract »  |  Full Text »  |  PDF »

In Prostate Cancer Cells the Interaction of C/EBP{alpha} with Ku70, Ku80, and Poly(ADP-ribose) Polymerase-1 Increases Sensitivity to DNA Damage.

H. Yin and J. Glass (2006)
J. Biol. Chem. 281, 11496-11505
 |  Abstract »  |  Full Text »  |  PDF »

Absence of the transcription factor CCAAT enhancer binding protein {alpha} results in loss of myeloid identity in bcr/abl-induced malignancy.

K. Wagner, P. Zhang, F. Rosenbauer, B. Drescher, S. Kobayashi, H. S. Radomska, J. L. Kutok, D. G. Gilliland, J. Krauter, and D. G. Tenen (2006)
PNAS 103, 6338-6343
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Regulation of Metabolism.

B. Desvergne, L. Michalik, and W. Wahli (2006)
Physiol Rev 86, 465-514
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Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer..

Y. Tada, R. M. Brena, B. Hackanson, C. Morrison, G. A. Otterson, and C. Plass (2006)
J Natl Cancer Inst 98, 396-406
 |  Abstract »  |  Full Text »  |  PDF »

C/EBP{alpha} is required for lung maturation at birth.

P. C. Martis, J. A. Whitsett, Y. Xu, A.-K. T. Perl, H. Wan, and M. Ikegami (2006)
Development 133, 1155-1164
 |  Abstract »  |  Full Text »  |  PDF »

The Proline-Histidine-Rich CDK2/CDK4 Interaction Region of C/EBP{alpha} Is Dispensable for C/EBP{alpha}-Mediated Growth Regulation In Vivo.

B. T. Porse, T. A. Pedersen, M. S. Hasemann, M. B. Schuster, P. Kirstetter, T. Luedde, I. Damgaard, E. Kurz, C. K. Schjerling, and C. Nerlov (2006)
Mol. Cell. Biol. 26, 1028-1037
 |  Abstract »  |  Full Text »  |  PDF »

Respiratory Failure Due to Differentiation Arrest and Expansion of Alveolar Cells following Lung-Specific Loss of the Transcription Factor C/EBP{alpha} in Mice.

D. S. Basseres, E. Levantini, H. Ji, S. Monti, S. Elf, T. Dayaram, M. Fenyus, O. Kocher, T. Golub, K.-k. Wong, et al. (2006)
Mol. Cell. Biol. 26, 1109-1123
 |  Abstract »  |  Full Text »  |  PDF »

Metabolic Response of Mice to a Postnatal Ablation of CCAAT/Enhancer-binding Protein {alpha}.

J. Yang, C. M. Croniger, J. Lekstrom-Himes, P. Zhang, M. Fenyus, D. G. Tenen, G. J. Darlington, and R. W. Hanson (2005)
J. Biol. Chem. 280, 38689-38699
 |  Abstract »  |  Full Text »  |  PDF »

CCAAT/Enhancer Binding Protein {alpha} Knock-in Mice Exhibit Early Liver Glycogen Storage and Reduced Susceptibility to Hepatocellular Carcinoma.

E. H. Tan, S. C. Hooi, M. Laban, E. Wong, S. Ponniah, A. Wee, and N.-d. Wang (2005)
Cancer Res. 65, 10330-10337
 |  Abstract »  |  Full Text »  |  PDF »

C/EBP{alpha} functionally and physically interacts with GABP to activate the human myeloid IgA Fc receptor (Fc{alpha}R, CD89) gene promoter.

T. Shimokawa and C. Ra (2005)
Blood 106, 2534-2542
 |  Abstract »  |  Full Text »  |  PDF »

Loss of C/EBP{alpha} cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage.

B. T. Porse, D. Bryder, K. Theilgaard-Monch, M. S. Hasemann, K. Anderson, I. Damgaard, S. E. W. Jacobsen, and C. Nerlov (2005)
J. Exp. Med. 202, 85-96
 |  Abstract »  |  Full Text »  |  PDF »

Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation.

Y. Fu, N. Luo, R. L. Klein, and W. T. Garvey (2005)
J. Lipid Res. 46, 1369-1379
 |  Abstract »  |  Full Text »  |  PDF »

Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors.

P. F. Johnson (2005)
J. Cell Sci. 118, 2545-2555
 |  Abstract »  |  Full Text »  |  PDF »

Transgenic and Knockout Mice in Diabetes Research: Novel Insights into Pathophysiology, Limitations, and Perspectives.

L. Plum, F. T. Wunderlich, S. Baudler, W. Krone, and J. C. Bruning (2005)
Physiology 20, 152-161
 |  Abstract »  |  Full Text »  |  PDF »

Down-Regulation and Growth Inhibitory Role of C/EBP{alpha} in Breast Cancer.

S. Gery, S. Tanosaki, S. Bose, N. Bose, J. Vadgama, and H. P. Koeffler (2005)
Clin. Cancer Res. 11, 3184-3190
 |  Abstract »  |  Full Text »  |  PDF »

3',5'-Cyclic Adenosine Monophosphate Response Element-Binding Protein and CCAAT Enhancer-Binding Protein Are Dispensable for Insulin Inhibition of Phosphoenolpyruvate Carboxykinase Transcription and for Its Synergistic Induction by Protein Kinase A and Glucocorticoids.

D. Yeagley and P. G. Quinn (2005)
Mol. Endocrinol. 19, 913-924
 |  Abstract »  |  Full Text »  |  PDF »

Chronic Hyperglycemia Enhances PEPCK Gene Expression and Hepatocellular Glucose Production Via Elevated Liver Activating Protein/Liver Inhibitory Protein Ratio.

J. Shao, L. Qiao, R. C. Janssen, M. Pagliassotti, and J. E. Friedman (2005)
Diabetes 54, 976-984
 |  Abstract »  |  Full Text »  |  PDF »

Signal Transducers and Activators of Transcription 3 Augments the Transcriptional Activity of CCAAT/Enhancer-binding Protein {alpha} in Granulocyte Colony-stimulating Factor Signaling Pathway.

A. Numata, K. Shimoda, K. Kamezaki, T. Haro, H. Kakumitsu, K. Shide, K. Kato, T. Miyamoto, Y. Yamashita, Y. Oshima, et al. (2005)
J. Biol. Chem. 280, 12621-12629
 |  Abstract »  |  Full Text »  |  PDF »

The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinoma.

K.-T. Chin, H.-J. Zhou, C.-M. Wong, J. M.-F. Lee, C.-P. Chan, B.-Q. Qiang, J.-G. Yuan, I. O.-l. Ng, and D.-Y. Jin (2005)
Nucleic Acids Res. 33, 1859-1873
 |  Abstract »  |  Full Text »  |  PDF »

Col1a1 Promoter-targeted Expression of p20 CCAAT Enhancer-binding Protein {beta} (C/EBP{beta}), a Truncated C/EBP{beta} Isoform, Causes Osteopenia in Transgenic Mice.

J. R. Harrison, Y.-F. Huang, K. A. Wilson, P. L. Kelly, D. J. Adams, G. A. Gronowicz, and S. H. Clark (2005)
J. Biol. Chem. 280, 8117-8124
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Wnt Signaling on Brown Adipocyte Differentiation and Metabolism Mediated by PGC-1{alpha}.

S. Kang, L. Bajnok, K. A. Longo, R. K. Petersen, J. B. Hansen, K. Kristiansen, and O. A. MacDougald (2005)
Mol. Cell. Biol. 25, 1272-1282
 |  Abstract »  |  Full Text »  |  PDF »

Interaction between GATA and the C/EBP Family of Transcription Factors Is Critical in GATA-Mediated Suppression of Adipocyte Differentiation.

Q. Tong, J. Tsai, G. Tan, G. Dalgin, and G. S. Hotamisligil (2005)
Mol. Cell. Biol. 25, 706-715
 |  Abstract »  |  Full Text »  |  PDF »

REGULATION OF GLUCOCORTICOID-INDUCIBLE HYDROXYSTEROID SULFOTRANSFERASE (SULT2A-40/41) GENE TRANSCRIPTION IN PRIMARY CULTURED RAT HEPATOCYTES: ROLE OF CCAAT/ENHANCER-BINDING PROTEIN LIVER-ENRICHED TRANSCRIPTION FACTORS.

H.-L. Fang, M. Abdolalipour, Z. Duanmu, J. R. Smigelski, A. Weckle, T. A. Kocarek, and M. Runge-Morris (2005)
Drug Metab. Dispos. 33, 147-156
 |  Abstract »  |  Full Text »  |  PDF »

A Distal Region Involving Hepatocyte Nuclear Factor 4{alpha} and CAAT/Enhancer Binding Protein Markedly Potentiates the Protein Kinase A Stimulation of the Glucose-6-Phosphatase Promoter.

A. Gautier-Stein, G. Mithieux, and F. Rajas (2005)
Mol. Endocrinol. 19, 163-174
 |  Abstract »  |  Full Text »  |  PDF »

Essential Requirement of CCAAT/Enhancer Binding Proteins in Embryogenesis.

V. Begay, J. Smink, and A. Leutz (2004)
Mol. Cell. Biol. 24, 9744-9751
 |  Abstract »  |  Full Text »  |  PDF »

Hepatic CCAAT/Enhancer Binding Protein {alpha} Mediates Induction of Lipogenesis and Regulation of Glucose Homeostasis in Leptin-Deficient Mice.

K. Matsusue, O. Gavrilova, G. Lambert, H. B. Brewer Jr., J. M. Ward, Y. Inoue, D. LeRoith, and F. J. Gonzalez (2004)
Mol. Endocrinol. 18, 2751-2764
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of Hepatic C/EBP{alpha} Results in Impaired Glucose Tolerance and Age-dependent Hepatosteatosis.

Y. Inoue, J. Inoue, G. Lambert, S. H. Yim, and F. J. Gonzalez (2004)
J. Biol. Chem. 279, 44740-44748
 |  Abstract »  |  Full Text »  |  PDF »

11{beta}-Hydroxysteroid Dehydrogenase Type 1: A Tissue-Specific Regulator of Glucocorticoid Response.

J. W. Tomlinson, E. A. Walker, I. J. Bujalska, N. Draper, G. G. Lavery, M. S. Cooper, M. Hewison, and P. M. Stewart (2004)
Endocr. Rev. 25, 831-866
 |  Abstract »  |  Full Text »  |  PDF »

The Transcription Factor CCAAT/Enhancer-binding Protein {alpha} Is Required for the Intracellular Retention of GLUT4.

N. Wertheim, Z. Cai, and T. E. McGraw (2004)
J. Biol. Chem. 279, 41468-41476
 |  Abstract »  |  Full Text »  |  PDF »

C/EBP{alpha} deficiency results in hyperproliferation of hematopoietic progenitor cells and disrupts macrophage development in vitro and in vivo.

V. Heath, H. C. Suh, M. Holman, K. Renn, J. M. Gooya, S. Parkin, K. D. Klarmann, M. Ortiz, P. Johnson, and J. Keller (2004)
Blood 104, 1639-1647
 |  Abstract »  |  Full Text »  |  PDF »

The Developmental Regulation of Peroxisome Proliferator-Activated Receptor-{gamma} Coactivator-1{alpha} Expression in the Liver Is Partially Dissociated from the Control of Gluconeogenesis and Lipid Catabolism.

P. Yubero, E. Hondares, M. C. Carmona, M. Rossell, F. J. Gonzalez, R. Iglesias, M. Giralt, and F. Villarroya (2004)
Endocrinology 145, 4268-4277
 |  Abstract »  |  Full Text »  |  PDF »

Glut4 Storage Vesicles without Glut4: Transcriptional Regulation of Insulin-Dependent Vesicular Traffic.

D. N. Gross, S. R. Farmer, and P. F. Pilch (2004)
Mol. Cell. Biol. 24, 7151-7162
 |  Abstract »  |  Full Text »  |  PDF »

The Novel Gene fad158, Having a Transmembrane Domain and Leucine-rich Repeat, Stimulates Adipocyte Differentiation.

K. Tominaga, C. Kondo, T. Kagata, T. Hishida, M. Nishizuka, and M. Imagawa (2004)
J. Biol. Chem. 279, 34840-34848
 |  Abstract »  |  Full Text »  |  PDF »

Lipin Expression Preceding Peroxisome Proliferator-activated Receptor-{gamma} Is Critical for Adipogenesis in Vivo and in Vitro.

J. Phan, M. Peterfy, and K. Reue (2004)
J. Biol. Chem. 279, 29558-29564
 |  Abstract »  |  Full Text »  |  PDF »

Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors.

N. Tanimizu and A. Miyajima (2004)
J. Cell Sci. 117, 3165-3174
 |  Abstract »  |  Full Text »  |  PDF »

Genetically Modified Animals in Endocrinology.

(2004)
Endocr. Rev. 25, 512-519
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Selective stimulation of G-6-Pase catalytic subunit but not G-6-P transporter gene expression by glucagon in vivo and cAMP in situ.

L. A. Hornbuckle, C. A. Everett, C. C. Martin, S. S. Gustavson, C. A. Svitek, J. K. Oeser, D. W. Neal, A. D. Cherrington, and R. M. O'Brien (2004)
Am J Physiol Endocrinol Metab 286, E795-E808
 |  Abstract »  |  Full Text »  |  PDF »

CCAAT Enhancer-binding Protein {alpha} Is Required for Interleukin-6 Receptor {alpha} Signaling in Newborn Hepatocytes.

S. L. Mackey and G. J. Darlington (2004)
J. Biol. Chem. 279, 16206-16213
 |  Abstract »  |  Full Text »  |  PDF »

Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP{alpha} growth inhibitory activity.

G.-L. Wang, P. Iakova, M. Wilde, S. Awad, and N. A. Timchenko (2004)
Genes & Dev. 18, 912-925
 |  Abstract »  |  Full Text »  |  PDF »

{Delta}FosB Induces Osteosclerosis and Decreases Adipogenesis by Two Independent Cell-Autonomous Mechanisms.

M. Kveiborg, G. Sabatakos, R. Chiusaroli, M. Wu, W. M. Philbrick, W. C. Horne, and R. Baron (2004)
Mol. Cell. Biol. 24, 2820-2830
 |  Abstract »  |  Full Text »  |  PDF »

Lipopenia and Skin Barrier Abnormalities in DGAT2-deficient Mice.

S. J. Stone, H. M. Myers, S. M. Watkins, B. E. Brown, K. R. Feingold, P. M. Elias, and R. V. Farese Jr. (2004)
J. Biol. Chem. 279, 11767-11776
 |  Abstract »  |  Full Text »  |  PDF »

A Role for CCAAT/Enhancer-Binding Protein {beta} in the Basal Regulation of the Distal-Less 3 Gene Promoter in Placental Cells.

M. P. Holland, S. P. Bliss, K. A. Berghorn, and M. S. Roberson (2004)
Endocrinology 145, 1096-1105
 |  Abstract »  |  Full Text »  |  PDF »

Thymulin evokes IL-6-C/EBP{beta} regenerative repair and TNF-{alpha} silencing during endotoxin exposure in fetal lung explants.

S. C. Land and F. Darakhshan (2004)
Am J Physiol Lung Cell Mol Physiol 286, L473-L487
 |  Abstract »  |  Full Text »  |  PDF »

The CCAAT Enhancer-binding Protein {alpha} (C/EBP{alpha}) Requires a SWI/SNF Complex for Proliferation Arrest.

C. Muller, C. F. Calkhoven, X. Sha, and A. Leutz (2004)
J. Biol. Chem. 279, 7353-7358
 |  Abstract »  |  Full Text »  |  PDF »

Lipogenesis in Fetal Rat Lung: Importance of C/EBP{alpha}, SREBP-1c, and Stearoyl-CoA Desaturase.

F. Zhang, T. Pan, L. D. Nielsen, and R. J. Mason (2004)
Am. J. Respir. Cell Mol. Biol. 30, 174-183
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of C/EBP{alpha} Inhibits Granulopoiesis.

S. E. Ross, H. S. Radomska, B. Wu, P. Zhang, J. N. Winnay, L. Bajnok, W. S. Wright, F. Schaufele, D. G. Tenen, and O. A. MacDougald (2004)
Mol. Cell. Biol. 24, 675-686
 |  Abstract »  |  Full Text »  |  PDF »

Brown Adipose Tissue: Function and Physiological Significance.

B. CANNON and J. NEDERGAARD (2004)
Physiol Rev 84, 277-359
 |  Abstract »  |  Full Text »  |  PDF »

RUNX/AML and C/EBP factors regulate CD11a integrin expression in myeloid cells through overlapping regulatory elements.

A. Puig-Kroger, T. Sanchez-Elsner, N. Ruiz, E. J. Andreu, F. Prosper, U. B. Jensen, J. Gil, P. Erickson, H. Drabkin, Y. Groner, et al. (2003)
Blood 102, 3252-3261
 |  Abstract »  |  Full Text »  |  PDF »

C/EBP transcription factors in the lung epithelium.

T. N. Cassel and M. Nord (2003)
Am J Physiol Lung Cell Mol Physiol 285, L773-L781
 |  Abstract »  |  Full Text »  |  PDF »

ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating {beta}1 integrin function.

N. Kawaguchi, C. Sundberg, M. Kveiborg, B. Moghadaszadeh, M. Asmar, N. Dietrich, C. K. Thodeti, F. C. Nielsen, P. Moller, A. M. Mercurio, et al. (2003)
J. Cell Sci. 116, 3893-3904
 |  Abstract »  |  Full Text »  |  PDF »

Transcription activation function of C/EBP{alpha} is required for induction of granulocytic differentiation.

K. Keeshan, G. Santilli, F. Corradini, D. Perrotti, and B. Calabretta (2003)
Blood 102, 1267-1275
 |  Abstract »  |  Full Text »  |  PDF »

New Animal Models for Study of Metabolism Minireview Series.

R. W. Hanson (2003)
J. Biol. Chem. 278, 28357-28358
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Chromium(VI) Down-regulates Heavy Metal-induced Metallothionein Gene Transcription by Modifying Transactivation Potential of the Key Transcription Factor, Metal-responsive Transcription Factor 1.

S. Majumder, K. Ghoshal, D. Summers, S. Bai, J. Datta, and S. T. Jacob (2003)
J. Biol. Chem. 278, 26216-26226
 |  Abstract »  |  Full Text »  |  PDF »

Vitamin A Depletion Is Associated with Low Phosphoenolpyruvate Carboxykinase mRNA Levels during Late Fetal Development and at Birth in Mice.

S. Ghoshal, S. Pasham, D. P. Odom, H. C. Furr, and M. M. McGrane (2003)
J. Nutr. 133, 2131-2136
 |  Abstract »  |  Full Text »  |  PDF »

Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells.

A. Suzuki, A. Iwama, H. Miyashita, H. Nakauchi, and H. Taniguchi (2003)
Development 130, 2513-2524
 |  Abstract »  |  Full Text »  |  PDF »

Lithium Stabilizes the CCAAT/Enhancer-binding Protein {alpha} (C/EBP{alpha}) through a Glycogen Synthase Kinase 3 (GSK3)-independent Pathway Involving Direct Inhibition of Proteasomal Activity.

M. Shim and R. C. Smart (2003)
J. Biol. Chem. 278, 19674-19681
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Regulation of Human CYP3A4 Basal Expression by CCAAT Enhancer-Binding Protein alpha and Hepatocyte Nuclear Factor-3gamma.

C. Rodriguez-Antona, R. Bort, R. Jover, N. Tindberg, M. Ingelman-Sundberg, M. J. Gomez-Lechon, and J. V. Castell (2003)
Mol. Pharmacol. 63, 1180-1189
 |  Abstract »  |  Full Text »  |  PDF »

Chromatin immunoprecipitation (ChIP) studies indicate a role for CCAAT enhancer binding proteins alpha and epsilon (C/EBPalpha and C/EBPepsilon ) and CDP/cut in myeloid maturation-induced lactoferrin gene expression.

A. Khanna-Gupta, T. Zibello, H. Sun, P. Gaines, and N. Berliner (2003)
Blood 101, 3460-3468
 |  Abstract »  |  Full Text »  |  PDF »

Structural Basis for DNA Recognition by the Basic Region Leucine Zipper Transcription Factor CCAAT/Enhancer-binding Protein alpha.

M. Miller, J. D. Shuman, T. Sebastian, Z. Dauter, and P. F. Johnson (2003)
J. Biol. Chem. 278, 15178-15184
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBPepsilon and PU.1.

A. F. Gombart, S. H. Kwok, K. L. Anderson, Y. Yamaguchi, B. E. Torbett, and H. P. Koeffler (2003)
Blood 101, 3265-3273
 |  Abstract »  |  Full Text »  |  PDF »

Posttranscriptional and Posttranslational Regulation of C/EBPdelta in G0 Growth-arrested Mammary Epithelial Cells.

L. R. Dearth and J. DeWille (2003)
J. Biol. Chem. 278, 11246-11255
 |  Abstract »  |  Full Text »  |  PDF »

Induction of C/EBPalpha activity alters gene expression and differentiation of human CD34+ cells.

J. Cammenga, J. C. Mulloy, F. J. Berguido, D. MacGrogan, A. Viale, and S. D. Nimer (2003)
Blood 101, 2206-2214
 |  Abstract »  |  Full Text »  |  PDF »

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