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Science 7 July 1995:
Vol. 269. no. 5220, pp. 86 - 89
DOI: 10.1126/science.7604284
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Articles

Science, Vol 269, Issue 5220, 86-89
Copyright © 1995 by American Association for the Advancement of Science

articles

Tissue- and species-specific expression of sp56, a mouse sperm fertilization protein

LH Bookbinder, A Cheng, and JD Bleil

Scripps Research Institute, Department of Molecular Biology, La Jolla, CA 92037, USA.

Mouse sperm recognize and bind to ZP3, one of three glycoproteins in the egg's zona pellucida. A mouse sperm protein, sp56, was identified that has the characteristics expected of the sperm protein responsible for recognition of ZP3. The complementary DNA encoding sp56 was isolated, and its primary sequence indicates that sp56 is a member of a superfamily of protein receptors. It was shown that sp56 expression is restricted to mouse spermatids and that the presence or absence of sp56 on sperm from different species accounts for species specificity of sperm-egg recognition in mice.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Recombinant Mouse Sperm ZP3-binding Protein (ZP3R/sp56) Forms a High Order Oligomer That Binds Eggs and Inhibits Mouse Fertilization in Vitro.
M. G. Buffone, T. Zhuang, T. S. Ord, L. Hui, S. B. Moss, and G. L. Gerton (2008)
J. Biol. Chem. 283, 12438-12445
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Mechanism of Self-Sterility in a Hermaphroditic Chordate.
Y. Harada, Y. Takagaki, M. Sunagawa, T. Saito, L. Yamada, H. Taniguchi, E. Shoguchi, and H. Sawada (2008)
Science 320, 548-550
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ERp57 is a potential biomarker for human fertilization capability.
J. Zhang, J. Wu, R. Huo, Y. Mao, Y. Lu, X. Guo, J. Liu, Z. Zhou, X. Huang, and J. Sha (2007)
Mol. Hum. Reprod. 13, 633-639
   Abstract »    Full Text »    PDF »
Molecular Models for Murine Sperm-Egg Binding.
G. F. Clark and A. Dell (2006)
J. Biol. Chem. 281, 13853-13856
   Abstract »    Full Text »    PDF »
Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis.
I. Martianov, S. Brancorsini, R. Catena, A. Gansmuller, N. Kotaja, M. Parvinen, P. Sassone-Corsi, and I. Davidson (2005)
PNAS 102, 2808-2813
   Abstract »    Full Text »    PDF »
Zonadhesin Assembly into the Hamster Sperm Acrosomal Matrix Occurs by Distinct Targeting Strategies During Spermiogenesis and Maturation in the Epididymis.
G. E. Olson, V. P. Winfrey, M. Bi, D. M. Hardy, and S. K. NagDas (2004)
Biol Reprod 71, 1128-1134
   Abstract »    Full Text »    PDF »
Complement C4b-Binding Protein as a Novel Murine Epididymal Secretory Protein.
M. I. Nonaka, Y. Hishikawa, N. Moriyama, T. Koji, R. T. Ogata, A. Kudo, H. Kawakami, and M. Nonaka (2003)
Biol Reprod 69, 1931-1939
   Abstract »    Full Text »    PDF »
Disruption of Mouse CD46 Causes an Accelerated Spontaneous Acrosome Reaction in Sperm.
N. Inoue, M. Ikawa, T. Nakanishi, M. Matsumoto, M. Nomura, T. Seya, and M. Okabe (2003)
Mol. Cell. Biol. 23, 2614-2622
   Abstract »    Full Text »    PDF »
Role of Sperm Surface Arylsulfatase A in Mouse Sperm-Zona Pellucida Binding.
J. Tantibhedhyangkul, W. Weerachatyanukul, E. Carmona, H. Xu, A. Anupriwan, D. Michaud, and N. Tanphaichitr (2002)
Biol Reprod 67, 212-219
   Abstract »    Full Text »    PDF »
Interactions between mouse ZP2 glycoprotein and proacrosin; a mechanism for secondary binding of sperm to the zona pellucida during fertilization.
E. Howes, J. C. Pascall, W. Engel, and R. Jones (2002)
J. Cell Sci. 114, 4127-4136
   Abstract »    Full Text »    PDF »
Molecular Basis of Mammalian Gamete Binding.
D. J. Miller, X. Shi, and H. Burkin (2002)
Recent Prog. Horm. Res. 57, 37-73
   Abstract »    Full Text »    PDF »
Anti-SLIP1-reactive proteins exist on human spermatozoa and are involved in zona pellucida binding.
M. Rattanachaiyanont, W. Weerachatyanukul, M.-C. Leveille, T. Taylor, D. D'Amours, D. Rivers, A. Leader, and N. Tanphaichitr (2001)
Mol. Hum. Reprod. 7, 633-640
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Glycobiology of sperm-egg interactions in deuterostomes.
K. J. Mengerink and V. D. Vacquier (2001)
Glycobiology 11, 37R-43R
   Abstract »    Full Text »    PDF »
Novel Androgen-Dependent Promoters Direct Expression of the C4b-Binding Protein {{alpha}}-Chain Gene in Epididymis.
M. I. Nonaka, G. Wang, T. Mori, H. Okada, and M. Nonaka (2001)
J. Immunol. 166, 4570-4577
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Cell surface beta-1,4-galactosyltransferase-I activates G protein-dependent exocytotic signaling.
X Shi, S Amindari, K Paruchuru, D Skalla, H Burkin, B. Shur, and D. Miller (2001)
Development 128, 645-654
   Abstract »    PDF »
Mouse Sperm Protein sp56 Is a Component of the Acrosomal Matrix.
K.-S. Kim, M. C. Cha, and G. L. Gerton (2001)
Biol Reprod 64, 36-43
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Differential Release of Guinea Pig Sperm Acrosomal Components During Exocytosis.
K.-S. Kim, J. A. Foster, and G. L. Gerton (2001)
Biol Reprod 64, 148-156
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Systematic Characterization of Sperm-Specific Membrane Proteins in Swine.
N. P. Haden, J. R. Hickox, C. Scott Whisnant, and D. M. Hardy (2000)
Biol Reprod 63, 1839-1847
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Structural Analysis of Murine Zona Pellucida Glycans. EVIDENCE FOR THE EXPRESSION OF CORE 2-TYPE O-GLYCANS AND THE Sda ANTIGEN.
R. L. Easton, M. S. Patankar, F. A. Lattanzio, T. H. Leaven, H. R. Morris, G. F. Clark, and A. Dell (2000)
J. Biol. Chem. 275, 7731-7742
   Abstract »    Full Text »    PDF »
Two distinct forms of the 64,000 Mr protein of the cleavage stimulation factor are expressed in mouse male germ cells.
A. M. Wallace, B. Dass, S. E. Ravnik, V. Tonk, N. A. Jenkins, D. J. Gilbert, N. G. Copeland, and C. C. MacDonald (1999)
PNAS 96, 6763-6768
   Abstract »    Full Text »    PDF »
Ion Channels in Sperm Physiology.
A. Darszon, P. Labarca, T. Nishigaki, and F. Espinosa (1999)
Physiol Rev 79, 481-510
   Abstract »    Full Text »    PDF »
Evolution of Gamete Recognition Proteins.
V. D. Vacquier (1998)
Science 281, 1995-1998
   Abstract »    Full Text »
Hetero-oligomerization-dependent Binding of Pig Oocyte Zona Pellucida Glycoproteins ZPB and ZPC to Boar Sperm Membrane Vesicles.
E. C. Yurewicz, A. G. Sacco, S. K. Gupta, N. Xu, and D. A. Gage (1998)
J. Biol. Chem. 273, 7488-7494
   Abstract »    Full Text »    PDF »
Murine Sperm-Zona Binding, A Fucosyl Residue Is Required for a High Affinity Sperm-binding Ligand. A SECOND SITE ON SPERM BINDS A NONFUCOSYLATED, beta -GALACTOSYL-CAPPED OLIGOSACCHARIDE.
D. S. Johnston, W. W. Wright, J. H. Shaper, C. H. Hokke, D. H. Van den Eijnden, and D. H. Joziasse (1998)
J. Biol. Chem. 273, 1888-1895
   Abstract »    Full Text »    PDF »
The abalone egg vitelline envelope receptor for sperm lysin is a giant multivalent molecule.
W. J. Swanson and V. D. Vacquier (1997)
PNAS 94, 6724-6729
   Abstract »    Full Text »    PDF »
Sperm from beta 1,4-galactosyltransferase-null mice are refractory to ZP3-induced acrosome reactions and penetrate the zona pellucida poorly.
Q Lu and B. Shur (1997)
Development 124, 4121-4131
   Abstract »    PDF »
Imparting Exquisite Specificity to Peanut Agglutinin for the Tumor-associated Thomsen-Friedenreich Antigen by Redesign of Its Combining Site.
V. Sharma, M. Vijayan, and A. Surolia (1996)
J. Biol. Chem. 271, 21209-21213
   Abstract »    Full Text »    PDF »
A Sperm Membrane Protein That Binds in a Species-specific Manner to the Egg Extracellular Matrix Is Homologous to von Willebrand Factor.
D. M. Hardy and D. L. Garbers (1995)
J. Biol. Chem. 270, 26025-26028
   Abstract »    Full Text »    PDF »
The complexities of conception.
R. Aitken (1995)
Science 269, 39-40
   PDF »


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