Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 23 June 1995:
Vol. 268. no. 5218, pp. 1738 - 1740
DOI: 10.1126/science.268.5218.1738
Prev | Table of Contents | Next

Articles

A Combinatorial Approach to Materials Discovery

X. -D. Xiang 1, Xiaodong Sun 2, Gabriel Briceño 1, Yulin Lou 2, Kai-An Wang 1, Hauyee Chang 2, William G. Wallace-Freedman 2, Sung-Wei Chen 2, and Peter G. Schultz 3

1 Molecular Design Institute, Lawrence Berkeley Laboratory, Berkeley, CA 94720, USA.
2 Department of Chemistry, University of California, Berkeley, CA 94720, USA.
3 Molecular Design Institute, Lawrence Berkeley Laboratory, Berkeley, CA 94720, USA, and Department of Chemistry, University of California, Berkeley, CA 94720, USA.

A method that combines thin film deposition and physical masking techniques has been used for the parallel synthesis of spatially addressable libraries of solid-state materials. Arrays containing different combinations, stoichiometries, and deposition sequences of BaCO3, Bi2O3, CaO, CuO, PbO, SrCO3, and Y2O3 were generated with a series of binary masks. The arrays were sintered and BiSrCaCuO and YBaCuO superconducting films were identified. Samples as small as 200 micrometers by 200 micrometers in size were generated, corresponding to library densities of 10,000 sites per square inch. The ability to generate and screen combinatorial libraries of solid-state compounds, when coupled with theory and empirical observations, may significantly increase the rate at which novel electronic, magnetic, and optical materials are discovered and theoretical predictions tested.

Submitted on December 7, 1994
Accepted on March 24, 1995


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Combinatorial approach for ferroelectric material libraries prepared by liquid source misted chemical deposition method.
K. W. Kim, M. K. Jeon, K. S. Oh, T. S. Kim, Y. S. Kim, and S. I. Woo (2007)
PNAS 104, 1134-1139
   Abstract »    Full Text »    PDF »
Combinatorial discovery of oxidative dehydrogenation catalysts within the Mo-V-Nb-O system.
P. Cong, A. Dehestani, R. Doolen, D. M. Giaquinta, S. Guan, V. Markov, D. Poojary, K. Self, H. Turner, and W. H. Weinberg (1999)
PNAS 96, 11077-11080
   Abstract »    Full Text »    PDF »
Combinatorial Electrochemistry: A Highly Parallel, Optical Screening Method for Discovery of Better Electrocatalysts.
E. Reddington, A. Sapienza, B. Gurau, R. Viswanathan, S. Sarangapani, E. S. Smotkin, and T. E. Mallouk (1998)
Science 280, 1735-1737
   Abstract »    Full Text »
Polyolefin Spheres from Metallocenes Supported on Noninteracting Polystyrene.
S. B. Roscoe, J. M. Fréchet, J. F. Walzer, and A. J. Dias (1998)
Science 280, 270-273
   Abstract »    Full Text »
Identification of a Blue Photoluminescent Composite Material from a Combinatorial Library.
J. Wang, Y. Yoo, C. Gao, I. Takeuchi, X. Sun, H. Chang, X. Xiang, and P. G. Schultz (1998)
Science 279, 1712-1714
   Abstract »    Full Text »
A Rare-Earth Phosphor Containing One-Dimensional Chains Identified Through Combinatorial Methods.
E. Danielson, M. Devenney, D. M. Giaquinta, J. H. Golden, R. C. Haushalter, E. W. McFarland, D. M. Poojary, C. M. Reaves, W. H. Weinberg, and X. D. Wu (1998)
Science 279, 837-839
   Abstract »    Full Text »
A Class of Cobalt Oxide Magnetoresistance Materials Discovered with Combinatorial Synthesis.
G. Briceņo, H. Chang, X. Sun, P. G. Schultz, and X.-D. Xiang (1995)
Science 270, 273-275
   Abstract »    PDF »
From molecular diversity to catalysis: lessons from the immune system.
P. Schultz and R. Lerner (1995)
Science 269, 1835-1842
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)