Science 19 May 1995: Vol. 268. no. 5213, pp. 1049 - 1053 DOI: 10.1126/science.7754385

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Articles

The Bovine Immunodeficiency Virus Rev Protein: Identification of a Novel Lentiviral Bipartite Nuclear Localization Signal Harboring an Atypical Spacer Sequence.

A. Gomez Corredor and D. Archambault (2009)
J. Virol. 83, 12842-12853
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a selective nuclear import signal in adenosine deaminases acting on RNA.

S. Maas and W. M. Gommans (2009)
Nucleic Acids Res. 37, 5822-5829
 |  Abstract »  |  Full Text »  |  PDF »

Role of Importin Alpha8, a New Member of the Importin Alpha Family of Nuclear Transport Proteins, in Early Embryonic Development in Cattle.

J. Tejomurtula, K.-B. Lee, S. K. Tripurani, G. W. Smith, and J. Yao (2009)
Biol Reprod 81, 333-342
 |  Abstract »  |  Full Text »  |  PDF »

Possible Role for Cellular Karyopherins in Regulating Polyomavirus and Papillomavirus Capsid Assembly.

G. Bird, M. O'Donnell, J. Moroianu, and R. L. Garcea (2008)
J. Virol. 82, 9848-9857
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}.

G. Mitrousis, A. S. Olia, N. Walker-Kopp, and G. Cingolani (2008)
J. Biol. Chem. 283, 7877-7884
 |  Abstract »  |  Full Text »  |  PDF »

Ebola Virus VP24 Proteins Inhibit the Interaction of NPI-1 Subfamily Karyopherin {alpha} Proteins with Activated STAT1.

St. P. Reid, C. Valmas, O. Martinez, F. M. Sanchez, and C. F. Basler (2007)
J. Virol. 81, 13469-13477
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Sonchus Yellow Net Virus N Protein in Formation of Nuclear Viroplasms.

M. Deng, J. N. Bragg, S. Ruzin, D. Schichnes, D. King, M. M. Goodin, and A. O. Jackson (2007)
J. Virol. 81, 5362-5374
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Import of Bovine Papillomavirus Type 1 E1 Protein Is Mediated by Multiple Alpha Importins and Is Negatively Regulated by Phosphorylation near a Nuclear Localization Signal.

X.-L. Bian, G. Rosas-Acosta, Y.-C. Wu, and V. G. Wilson (2007)
J. Virol. 81, 2899-2908
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Localization Signal and Protein Context both Mediate Importin {alpha} Specificity of Nuclear Import Substrates.

B. Friedrich, C. Quensel, T. Sommer, E. Hartmann, and M. Kohler (2006)
Mol. Cell. Biol. 26, 8697-8709
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of hCINAP, a Novel Coilin-interacting Protein Encoded by a Transcript from the Transcription Factor TAFIID32 Locus.

N. Santama, S. C. Ogg, A. Malekkou, S. E. Zographos, K. Weis, and A. I. Lamond (2005)
J. Biol. Chem. 280, 36429-36441
 |  Abstract »  |  Full Text »  |  PDF »

Dissection of a Novel Nuclear Localization Signal in Open Reading Frame 29 of Varicella-Zoster Virus.

C. L. Stallings and S. Silverstein (2005)
J. Virol. 79, 13070-13081
 |  Abstract »  |  Full Text »  |  PDF »

Cross-Talk between Snurportin1 Subdomains.

J. K. Ospina, G. B. Gonsalvez, J. Bednenko, E. Darzynkiewicz, L. Gerace, and A. G. Matera (2005)
Mol. Biol. Cell 16, 4660-4671
 |  Abstract »  |  Full Text »  |  PDF »

Importin-{alpha} Promotes Passage through the Nuclear Pore Complex of Human Immunodeficiency Virus Type 1 Vpr.

M. Kamata, Y. Nitahara-Kasahara, Y. Miyamoto, Y. Yoneda, and Y. Aida (2005)
J. Virol. 79, 3557-3564
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Determinants for Subcellular Localization of Hepatitis C Virus Core Protein.

R. Suzuki, S. Sakamoto, T. Tsutsumi, A. Rikimaru, K. Tanaka, T. Shimoike, K. Moriishi, T. Iwasaki, K. Mizumoto, Y. Matsuura, et al. (2005)
J. Virol. 79, 1271-1281
 |  Abstract »  |  Full Text »  |  PDF »

The Positively Charged Termini of L2 Minor Capsid Protein Required for Bovine Papillomavirus Infection Function Separately in Nuclear Import and DNA Binding.

A. Fay, W. H. Yutzy IV, R. B. S. Roden, and J. Moroianu (2004)
J. Virol. 78, 13447-13454
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Analysis of Importin {alpha} Proteins Reveals Cellular Proliferation Inhibition and Substrate Specificity.

C. Quensel, B. Friedrich, T. Sommer, E. Hartmann, and M. Kohler (2004)
Mol. Cell. Biol. 24, 10246-10255
 |  Abstract »  |  Full Text »  |  PDF »

The L2 Minor Capsid Protein of Human Papillomavirus Type 16 Interacts with a Network of Nuclear Import Receptors.

M. S. Darshan, J. Lucchi, E. Harding, and J. Moroianu (2004)
J. Virol. 78, 12179-12188
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Nuclear Import by the Proapoptotic Protein CC3.

F. W. King and E. Shtivelman (2004)
Mol. Cell. Biol. 24, 7091-7101
 |  Abstract »  |  Full Text »  |  PDF »

Protein Interactions Involved in Nuclear Import of the Agrobacterium VirE2 Protein in Vivo and in Vitro.

V. Citovsky, A. Kapelnikov, S. Oliel, N. Zakai, M. R. Rojas, R. L. Gilbertson, T. Tzfira, and A. Loyter (2004)
J. Biol. Chem. 279, 29528-29533
 |  Abstract »  |  Full Text »  |  PDF »

Impaired V(D)J Recombination and Lymphocyte Development in Core RAG1-expressing Mice.

D. D. Dudley, J. Sekiguchi, C. Zhu, M. J. Sadofsky, S. Whitlow, J. DeVido, R. J. Monroe, C. H. Bassing, and F. W. Alt (2003)
J. Exp. Med. 198, 1439-1450
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of p120-catenin nucleocytoplasmic shuttling activity.

A. Roczniak-Ferguson and A. B. Reynolds (2003)
J. Cell Sci. 116, 4201-4212
 |  Abstract »  |  Full Text »  |  PDF »

A Nonconventional Nuclear Localization Signal within the UL84 Protein of Human Cytomegalovirus Mediates Nuclear Import via the Importin {alpha}/{beta} Pathway.

P. Lischka, G. Sorg, M. Kann, M. Winkler, and T. Stamminger (2003)
J. Virol. 77, 3734-3748
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Entry of High-Risk Human Papillomavirus Type 16 E6 Oncoprotein Occurs via Several Pathways.

L. G. Le Roux and J. Moroianu (2003)
J. Virol. 77, 2330-2337
 |  Abstract »  |  Full Text »  |  PDF »

Functional Proteomic Analysis of Human Nucleolus.

A. Scherl, Y. Coute, C. Deon, A. Calle, K. Kindbeiter, J.-C. Sanchez, A. Greco, D. Hochstrasser, and J.-J. Diaz (2002)
Mol. Biol. Cell 13, 4100-4109
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Import of Upf3p Is Mediated by Importin-{alpha}/-{beta} and Export to the Cytoplasm Is Required for a Functional Nonsense-Mediated mRNA Decay Pathway in Yeast.

R. L. Shirley, A. S. Ford, M. R. Richards, M. Albertini, and M. R. Culbertson (2002)
Genetics 161, 1465-1482
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Import Strategies of High Risk HPV16 L1 Major Capsid Protein.

L. M. Nelson, R. C. Rose, and J. Moroianu (2002)
J. Biol. Chem. 277, 23958-23964
 |  Abstract »  |  Full Text »  |  PDF »

Structure and function correlation in histone H2A peptide-mediated gene transfer.

D. Balicki, C. D. Putnam, P. V. Scaria, and E. Beutler (2002)
PNAS 99, 7467-7471
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of an Unusual Importin alpha Binding Motif in the Borna Disease Virus p10 Protein That Directs Nuclear Import.

T. Wolff, G. Unterstab, G. Heins, J. A. Richt, and M. Kann (2002)
J. Biol. Chem. 277, 12151-12157
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Nuclear Export Signal of Polypyrimidine Tract-binding Protein.

B. Li and T. S. B. Yen (2002)
J. Biol. Chem. 277, 10306-10314
 |  Abstract »  |  Full Text »  |  PDF »

Ribosomal Protein L12 Uses a Distinct Nuclear Import Pathway Mediated by Importin 11.

S. M. Plafker and I. G. Macara (2002)
Mol. Cell. Biol. 22, 1266-1275
 |  Abstract »  |  Full Text »  |  PDF »

The importin-{beta} binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro.

J. Huber, A. Dickmanns, and R. Luhrmann (2002)
J. Cell Biol. 156, 467-479
 |  Abstract »  |  Full Text »  |  PDF »

A developmentally regulated ARF-like 5 protein (ARL5), localized to nuclei and nucleoli, interacts with heterochromatin protein 1.

C.-Y. Lin, C.-C. Li, P.-H. Huang, and F.-J. S. Lee (2002)
J. Cell Sci. 115, 4433-4445
 |  Abstract »  |  Full Text »  |  PDF »

Transport into and out of the Nucleus.

I. G. Macara (2001)
Microbiol. Mol. Biol. Rev. 65, 570-594
 |  Abstract »  |  Full Text »  |  PDF »

MKP-7, a Novel Mitogen-activated Protein Kinase Phosphatase, Functions as a Shuttle Protein.

K. Masuda, H. Shima, M. Watanabe, and K. Kikuchi (2001)
J. Biol. Chem. 276, 39002-39011
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin {alpha} (Rch1{alpha}).

J. J. Perez-Villar, K. O'Day, D. H. Hewgill, S. G. Nadler, and S. B. Kanner (2001)
Int. Immunol. 13, 1265-1274
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Nuclear Import and Export That Control the Subcellular Localization of Class II Transactivator.

D. E. Cressman, W. J. O'Connor, S. F. Greer, X.-S. Zhu, and J. P.-Y. Ting (2001)
J. Immunol. 167, 3626-3634
 |  Abstract »  |  Full Text »  |  PDF »

Nup2p Dynamically Associates with the Distal Regions of the Yeast Nuclear Pore Complex.

D. J. Dilworth, A. Suprapto, J. C. Padovan, B. T. Chait, R. W. Wozniak, M. P. Rout, and J. D. Aitchison (2001)
J. Cell Biol. 153, 1465-1478
 |  Abstract »  |  Full Text »  |  PDF »

Cap methyltransferase selective binding and methylation of GpppG-RNA are stimulated by importin-{alpha}.

Y. Wen and A. J. Shatkin (2000)
Genes & Dev. 14, 2944-2949
 |  Abstract »  |  Full Text »

Nup2p, a Yeast Nucleoporin, Functions in Bidirectional Transport of Importin alpha.

J. Solsbacher, P. Maurer, F. Vogel, and G. Schlenstedt (2000)
Mol. Cell. Biol. 20, 8468-8479
 |  Abstract »  |  Full Text »

The potential terminase subunit of human cytomegalovirus, pUL56, is translocated into the nucleus by its own nuclear localization signal and interacts with importin {alpha}.

K. Giesen, K. Radsak, and E. Bogner (2000)
J. Gen. Virol. 81, 2231-2244
 |  Abstract »  |  Full Text »

The C-Terminal Proline-Rich Tail of Human Immunodeficiency Virus Type 2 Vpx Is Necessary for Nuclear Localization of the Viral Preintegration Complex in Nondividing Cells.

H. A. Pancio, N. Vander Heyden, and L. Ratner (2000)
J. Virol. 74, 6162-6167
 |  Abstract »  |  Full Text »

Relationship between Contact Inhibition and Intranuclear S100c of Normal Human Fibroblasts.

M. Sakaguchi, M. Miyazaki, Y. Inoue, T. Tsuji, H. Kouchi, T. Tanaka, H. Yamada, and M. Namba (2000)
J. Cell Biol. 149, 1193-1206
 |  Abstract »  |  Full Text »  |  PDF »

Gatekeepers of the Nucleus.

S. R. Wente (2000)
Science 288, 1374-1377
 |  Abstract »  |  Full Text »

Nuclear Import of the Ran Exchange Factor, Rcc1, Is Mediated by at Least Two Distinct Mechanisms.

M. E. Nemergut and I. G. Macara (2000)
J. Cell Biol. 149, 835-850
 |  Abstract »  |  Full Text »  |  PDF »

The Nuclear Import of RCC1 Requires a Specific Nuclear Localization Sequence Receptor, Karyopherin alpha 3/Qip.

B. Talcott and M. S. Moore (2000)
J. Biol. Chem. 275, 10099-10104
 |  Abstract »  |  Full Text »  |  PDF »

A Human Importin-beta Family Protein, Transportin-SR2, Interacts with the Phosphorylated RS Domain of SR Proteins.

M.-C. Lai, R.-I. Lin, S.-Y. Huang, C.-W. Tsai, and W.-Y. Tarn (2000)
J. Biol. Chem. 275, 7950-7957
 |  Abstract »  |  Full Text »  |  PDF »

An Atp-Dependent, Ran-Independent Mechanism for Nuclear Import of the U1a and U2b'' Spliceosome Proteins.

M. Hetzer and I. W. Mattaj (2000)
J. Cell Biol. 148, 293-304
 |  Abstract »  |  Full Text »  |  PDF »

RanBP3 Contains an Unusual Nuclear Localization Signal That Is Imported Preferentially by Importin-alpha 3.

K. Welch, J. Franke, M. Kohler, and I. G. Macara (1999)
Mol. Cell. Biol. 19, 8400-8411
 |  Abstract »  |  Full Text »  |  PDF »

A Bipartite Nuclear Localization Signal Is Required for p53 Nuclear Import Regulated by a Carboxyl-terminal Domain.

S.-H. Liang and M. F. Clarke (1999)
J. Biol. Chem. 274, 32699-32703
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for Distinct Substrate Specificities of Importin alpha Family Members in Nuclear Protein Import.

M. Kohler, C. Speck, M. Christiansen, F. R. Bischoff, S. Prehn, H. Haller, D. Gorlich, and E. Hartmann (1999)
Mol. Cell. Biol. 19, 7782-7791
 |  Abstract »  |  Full Text »  |  PDF »

Kap104p-mediated Nuclear Import. NUCLEAR LOCALIZATION SIGNALS IN mRNA-BINDING PROTEINS AND THE ROLE OF RAN AND RNA.

D. C. Y. Lee and J. D. Aitchison (1999)
J. Biol. Chem. 274, 29031-29037
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Import of Plasmid DNA in Digitonin-permeabilized Cells Requires Both Cytoplasmic Factors and Specific DNA Sequences.

G. L. Wilson, B. S. Dean, G. Wang, and D. A. Dean (1999)
J. Biol. Chem. 274, 22025-22032
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Import of Sterol Regulatory Element-binding Protein-2, a Basic Helix-Loop-Helix-Leucine Zipper (bHLH-Zip)-containing Transcription Factor, Occurs through the Direct Interaction of Importin beta with HLH-Zip.

E. Nagoshi, N. Imamoto, R. Sato, and Y. Yoneda (1999)
Mol. Biol. Cell 10, 2221-2233
 |  Abstract »  |  Full Text »

A Test of the Cytosolic Apolipoprotein E Hypothesis Fails to Detect the Escape of Apolipoprotein E from the Endocytic Pathway into the Cytosol and Shows that Direct Expression of Apolipoprotein E in the Cytosol is Cytotoxic.

R. B. DeMattos, F. E. Thorngate, and D. L. Williams (1999)
J. Neurosci. 19, 2464-2473
 |  Abstract »  |  Full Text »  |  PDF »

beta -Catenin Can Be Transported into the Nucleus in a Ran-unassisted Manner.

F. Yokoya, N. Imamoto, T. Tachibana, and Y. Yoneda (1999)
Mol. Biol. Cell 10, 1119-1131
 |  Abstract »  |  Full Text »

Characterization of Ikappa Balpha Nuclear Import Pathway.

P. Turpin, R. T. Hay, and C. Dargemont (1999)
J. Biol. Chem. 274, 6804-6812
 |  Abstract »  |  Full Text »  |  PDF »

The Nucleoporin Nup153 Plays a Critical Role in Multiple Types of Nuclear Export.

K. S. Ullman, S. Shah, M. A. Powers, and D. J. Forbes (1999)
Mol. Biol. Cell 10, 649-664
 |  Abstract »  |  Full Text »

Discrimination between NL1- and NL2-Mediated Nuclear Localization of the Glucocorticoid Receptor.

J. G. A. Savory, B. Hsu, I. R. Laquian, W. Giffin, T. Reich, R. J. G. Hache, and Y. A. Lefebvre (1999)
Mol. Cell. Biol. 19, 1025-1037
 |  Abstract »  |  Full Text »  |  PDF »

Interactions between a Nuclear Transporter and a Subset of Nuclear Pore Complex Proteins Depend on Ran GTPase.

M. Seedorf, M. Damelin, J. Kahana, T. Taura, and P. A. Silver (1999)
Mol. Cell. Biol. 19, 1547-1557
 |  Abstract »  |  Full Text »  |  PDF »

Ran-dependent Signal-mediated Nuclear Import Does Not Require GTP Hydrolysis by Ran.

E. D. Schwoebel, B. Talcott, I. Cushman, and M. S. Moore (1998)
J. Biol. Chem. 273, 35170-35175
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of NF-{kappa}B, AP-1, NFAT, and STAT1 Nuclear Import in T Lymphocytes by Noninvasive Delivery of Peptide Carrying the Nuclear Localization Sequence of NF-{kappa}B p50.

T. R. Torgerson, A. D. Colosia, J. P. Donahue, Y.-Z. Lin, and J. Hawiger (1998)
J. Immunol. 161, 6084-6092
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of HIV-1 Vpr Nuclear Import: Analysis of Signals and Pathways.

Y. Jenkins, M. McEntee, K. Weis, and W. C. Greene (1998)
J. Cell Biol. 143, 875-885
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear RNA export.

F. Stutz and M. Rosbash (1998)
Genes & Dev. 12, 3303-3319
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Determination of the Functional Domain Organization of the Importin {alpha} Nuclear Import Factor.

A. Herold, R. Truant, H. Wiegand, and B. R. Cullen (1998)
J. Cell Biol. 143, 309-318
 |  Abstract »  |  Full Text »  |  PDF »

Ran and Nuclear Transport.

M. S. Moore (1998)
J. Biol. Chem. 273, 22857-22860
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Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121.

A. Kaffman, N. M. Rank, and E. K. O'Shea (1998)
Genes & Dev. 12, 2673-2683
 |  Abstract »  |  Full Text »

Differential Importin-alpha Recognition and Nuclear Transport by Nuclear Localization Signals within the High-Mobility-Group DNA Binding Domains of Lymphoid Enhancer Factor 1 and T-Cell Factor 1.

M. G. Prieve, K. L. Guttridge, J. Munguia, and M. L. Waterman (1998)
Mol. Cell. Biol. 18, 4819-4832
 |  Abstract »  |  Full Text »

Functional Conservation of the Transportin Nuclear Import Pathway in Divergent Organisms.

M. C. Siomi, M. Fromont, J.-C. Rain, L. Wan, F. Wang, P. Legrain, and G. Dreyfuss (1998)
Mol. Cell. Biol. 18, 4141-4148
 |  Abstract »  |  Full Text »

CNI-H0294, a Nuclear Importation Inhibitor of the Human Immunodeficiency Virus Type 1 Genome, Abrogates Virus Replication in Infected Activated Peripheral Blood Mononuclear Cells.

O. K. Haffar, M. D. Smithgall, S. Popov, P. Ulrich, A. G. Bruce, S. G. Nadler, A. Cerami, and M. I. Bukrinsky (1998)
Antimicrob. Agents Chemother. 42, 1133-1138
 |  Abstract »  |  Full Text »

Hepatitis Delta Antigen Mediates the Nuclear Import of Hepatitis Delta Virus RNA.

H.-C. Chou, T.-Y. Hsieh, G.-T. Sheu, and M. M. C. Lai (1998)
J. Virol. 72, 3684-3690
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Localization of Ikappa Balpha Is Mediated by the Second Ankyrin Repeat: the Ikappa Balpha Ankyrin Repeats Define a Novel Class of cis-Acting Nuclear Import Sequences.

S. Sachdev, A. Hoffmann, and M. Hannink (1998)
Mol. Cell. Biol. 18, 2524-2534
 |  Abstract »  |  Full Text »

Identification of a Novel Cytoplasmic Protein That Specifically Binds to Nuclear Localization Signal Motifs.

S. Li, C.-Y. Ku, A. A. Farmer, Y.-S. Cong, C.-F. Chen, and W.-H. Lee (1998)
J. Biol. Chem. 273, 6183-6189
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of the Nucleoporin CAN/NUP214 Induces Growth Arrest, Nucleocytoplasmic Transport Defects, and Apoptosis.

J. Boer, J. Bonten-Surtel, and G. Grosveld (1998)
Mol. Cell. Biol. 18, 1236-1247
 |  Abstract »  |  Full Text »

Identification and Functional Characterization of a Novel Nuclear Localization Signal Present in the Yeast Nab2 Poly(A)+ RNA Binding Protein.

R. Truant, R. A. Fridell, R. E. Benson, H. Bogerd, and B. R. Cullen (1998)
Mol. Cell. Biol. 18, 1449-1458
 |  Abstract »  |  Full Text »

Nuclear Localization and Export Signals of the Human Aryl Hydrocarbon Receptor.

T. Ikuta, H. Eguchi, T. Tachibana, Y. Yoneda, and K. Kawajiri (1998)
J. Biol. Chem. 273, 2895-2904
 |  Abstract »  |  Full Text »  |  PDF »

The role of the ran GTPase in nuclear assembly and DNA replication: characterisation of the effects of Ran mutants.

M Hughes, C Zhang, J. Avis, C. Hutchison, and P. Clarke (1998)
J. Cell Sci. 111, 3017-3026
 |  Abstract »  |  PDF »

A T42A Ran Mutation: Differential Interactions with Effectors and Regulators, and Defect in Nuclear Protein Import.

G. A. Murphy, M. S. Moore, G. Drivas, P. P. de la Ossa, A. Villamarin, P. D'Eustachio, and M. G. Rush (1997)
Mol. Biol. Cell 8, 2591-2604
 |  Abstract »  |  Full Text »

Ran-unassisted Nuclear Migration of a 97-kD Component of Nuclear Pore-targeting Complex.

S. Kose, N. Imamoto, T. Tachibana, T. Shimamoto, and Y. Yoneda (1997)
J. Cell Biol. 139, 841-849
 |  Abstract »  |  Full Text »  |  PDF »

Nucleocytoplasmic Recycling of the Nuclear Localization Signal Receptor {alpha} Subunit In Vivo Is Dependent on a Nuclear Export Signal, Energy, and RCC1.

I. Boche and E. Fanning (1997)
J. Cell Biol. 139, 313-325
 |  Abstract »  |  Full Text »  |  PDF »

Differential Modes of Nuclear Localization Signal (NLS) Recognition by Three Distinct Classes of NLS Receptors.

Y. Miyamoto, N. Imamoto, T. Sekimoto, T. Tachibana, T. Seki, S. Tada, T. Enomoto, and Y. Yoneda (1997)
J. Biol. Chem. 272, 26375-26381
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for a Role of CRM1 in Signal-Mediated Nuclear Protein Export.

B. Ossareh-Nazari, F. Bachelerie, and C. Dargemont (1997)
Science 278, 141-144
 |  Abstract »  |  Full Text »

Nuclear localization signal binding protein from Arabidopsis mediates nuclear import of Agrobacterium VirD2 protein.

N. Ballas and V. Citovsky (1997)
PNAS 94, 10723-10728
 |  Abstract »  |  Full Text »  |  PDF »

Transportin-mediated Nuclear Import of Heterogeneous Nuclear RNP Proteins.

M. C. Siomi, P. S. Eder, N. Kataoka, L. Wan, Q. Liu, and G. Dreyfuss (1997)
J. Cell Biol. 138, 1181-1192
 |  Abstract »  |  Full Text »  |  PDF »

RanGTP-mediated nuclear export of karyopherin alpha  involves its interaction with the nucleoporin Nup153.

J. Moroianu, G. Blobel, and A. Radu (1997)
PNAS 94, 9699-9704
 |  Abstract »  |  Full Text »  |  PDF »

Association of the T-cell Protein Tyrosine Phosphatase with Nuclear Import Factor p97.

T. Tiganis, A. J. Flint, S. A. Adam, and N. K. Tonks (1997)
J. Biol. Chem. 272, 21548-21557
 |  Abstract »  |  Full Text »  |  PDF »

Disassembly of RanGTP-Karyopherin beta  Complex, an Intermediate in Nuclear Protein Import.

M. Floer, G. Blobel, and M. Rexach (1997)
J. Biol. Chem. 272, 19538-19546
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Class of RanGTP Binding Proteins.

D. Gorlich, M. Dabrowski, F. R. Bischoff, U. Kutay, P. Bork, E. Hartmann, S. Prehn, and E. Izaurralde (1997)
J. Cell Biol. 138, 65-80
 |  Abstract »  |  Full Text »  |  PDF »

A Nuclear Localization Signal of Human Aryl Hydrocarbon Receptor Nuclear Translocator/Hypoxia-inducible Factor 1beta Is a Novel Bipartite Type Recognized by the Two Components of Nuclear Pore-targeting Complex.

H. Eguchi, T. Ikuta, T. Tachibana, Y. Yoneda, and K. Kawajiri (1997)
J. Biol. Chem. 272, 17640-17647
 |  Abstract »  |  Full Text »  |  PDF »

The Protein Kinase CK2 Site (Ser111/112) Enhances Recognition of the Simian Virus 40 Large T-antigen Nuclear Localization Sequence by Importin.

S. Hubner, C.-Y. Xiao, and D. A. Jans (1997)
J. Biol. Chem. 272, 17191-17195
 |  Abstract »  |  Full Text »  |  PDF »

A Nuclear Export Signal in Kap95p Is Required for Both Recycling the Import Factor and Interaction with the Nucleoporin GLFG Repeat Regions of Nup116p and Nup100p.

M. K. Iovine and S. R. Wente (1997)
J. Cell Biol. 137, 797-811
 |  Abstract »  |  Full Text »  |  PDF »

Karyopherin beta 2 mediates nuclear import of a mRNA binding protein.

N. Bonifaci, J. Moroianu, A. Radu, and G. Blobel (1997)
PNAS 94, 5055-5060
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and characterization of human karyopherin beta 3.

N. R. Yaseen and G. Blobel (1997)
PNAS 94, 4451-4456
 |  Abstract »  |  Full Text »  |  PDF »

Different Binding Domains for Ran-GTP and Ran-GDP/RanBP1 on Nuclear Import Factor p97.

N. C. Chi, E. J.H. Adam, and S. A. Adam (1997)
J. Biol. Chem. 272, 6818-6822
 |  Abstract »  |  Full Text »  |  PDF »

Differential Expression and Sequence-specific Interaction of Karyopherin alpha with Nuclear Localization Sequences.

S. G. Nadler, D. Tritschler, O. K. Haffar, J. Blake, A. G. Bruce, and J. S. Cleaveland (1997)
J. Biol. Chem. 272, 4310-4315
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-beta.

R. Fridell, R Truant, L Thorne, R. Benson, and B. Cullen (1997)
J. Cell Sci. 110, 1325-1331
 |  Abstract »  |  PDF »

Ran-binding Protein 1(RanBP1) Forms a Ternary Complex with Ran and Karyopherin beta and Reduces Ran GTPase-activating Protein (RanGAP) Inhibition by Karyopherin beta.

K. M. Lounsbury and I. G. Macara (1997)
J. Biol. Chem. 272, 551-555
 |  Abstract »  |  Full Text »  |  PDF »

The Nuclear Localization Sequences of the BRCA1 Protein Interact with the Importin-alpha Subunit of the Nuclear Transport Signal Receptor.

C.-F. Chen, S. Li, Y. Chen, P.-L. Chen, Z. D. Sharp, and W.-H. Lee (1996)
J. Biol. Chem. 271, 32863-32868
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-gamma -dependent Nuclear Import of Stat1 Is Mediated by the GTPase Activity of Ran/TC4.

T. Sekimoto, K. Nakajima, T. Tachibana, T. Hirano, and Y. Yoneda (1996)
J. Biol. Chem. 271, 31017-31020
 |  Abstract »  |  Full Text »  |  PDF »

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