Science 14 April 1995: Vol. 268. no. 5208, pp. 247 - 251 DOI: 10.1126/science.7716516

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Articles

Down-Regulation of 3-Phosphoinositide-Dependent Protein Kinase-1 Levels Inhibits Migration and Experimental Metastasis of Human Breast Cancer Cells.

Y. Liu, J. Wang, M. Wu, W. Wan, R. Sun, D. Yang, X. Sun, D. Ma, G. Ying, and N. Zhang (2009)
Mol. Cancer Res. 7, 944-954
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C{delta} Differentially Regulates Platelet Functional Responses.

R. Chari, T. Getz, B. Nagy Jr, K. Bhavaraju, Y. Mao, Y. S. Bynagari, S. Murugappan, K. Nakayama, and S. P. Kunapuli (2009)
Arterioscler. Thromb. Vasc. Biol. 29, 699-705
 |  Abstract »  |  Full Text »  |  PDF »

An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.

P. J. Mintz, M. Cardo-Vila, M. G. Ozawa, A. Hajitou, R. Rangel, L. Guzman-Rojas, D. R. Christianson, M. A. Arap, R. J. Giordano, G. R. Souza, et al. (2009)
PNAS 106, 2182-2187
 |  Abstract »  |  Full Text »  |  PDF »

Rapid Estrogen Receptor-{alpha} Activation Improves Ischemic Tolerance in Aged Female Rats through a Novel Protein Kinase C{epsilon}-Dependent Mechanism.

J. L. Novotny, A. M. Simpson, N. J. Tomicek, T. S. Lancaster, and D. H. Korzick (2009)
Endocrinology 150, 889-896
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C Contributes to the Maintenance of Contractile Force in Human Ventricular Cardiomyocytes.

A. Molnar, A. Borbely, D. Czuriga, S. M. Ivetta, S. Szilagyi, Z. Hertelendi, E. T. Pasztor, A. Balogh, Z. Galajda, T. Szerafin, et al. (2009)
J. Biol. Chem. 284, 1031-1039
 |  Abstract »  |  Full Text »  |  PDF »

Ethanol for cardiac ischemia: the role of protein kinase c.

E. N. Churchill, M.-H. Disatnik, G. R. Budas, and D. Mochly-Rosen (2008)
Therapeutic Advances in Cardiovascular Disease 2, 469-483
 |  Abstract »  |  PDF »

Direct association of calponin with specific domains of PKC-{alpha}.

S. Somara and K. N. Bitar (2008)
Am J Physiol Gastrointest Liver Physiol 295, G1246-G1254
 |  Abstract »  |  Full Text »  |  PDF »

The Major Chemical-detoxifying System of UDP-glucuronosyltransferases Requires Regulated Phosphorylation Supported by Protein Kinase C.

N. K. Basu, L. Kole, M. Basu, K. Chakraborty, P. S. Mitra, and I. S. Owens (2008)
J. Biol. Chem. 283, 23048-23061
 |  Abstract »  |  Full Text »  |  PDF »

Stromal cell-derived factor 1-{alpha} (SDF)-induced human T cell chemotaxis becomes phosphoinositide 3-kinase (PI3K)-independent: role of PKC-{theta}.

N. A. Shahabi, K. McAllen, and B. M. Sharp (2008)
J. Leukoc. Biol. 83, 663-671
 |  Abstract »  |  Full Text »  |  PDF »

Intracoronary KAI-9803 as an Adjunct to Primary Percutaneous Coronary Intervention for Acute ST-Segment Elevation Myocardial Infarction.

Direct Inhibition of {delta}-Protein Kinase C Enzy (2008)
Circulation 117, 886-896
 |  Abstract »  |  Full Text »  |  PDF »

Direct Binding and Activation of Protein Kinase C Isoforms by Aldosterone and 17{beta}-Estradiol.

R. Alzamora, L. R. Brown, and B. J. Harvey (2007)
Mol. Endocrinol. 21, 2637-2650
 |  Abstract »  |  Full Text »  |  PDF »

Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function.

F. G. Spinale (2007)
Physiol Rev 87, 1285-1342
 |  Abstract »  |  Full Text »  |  PDF »

Emerin Is Hyperphosphorylated and Redistributed in Herpes Simplex Virus Type 1-Infected Cells in a Manner Dependent on both UL34 and US3.

N. Leach, S. L. Bjerke, D. K. Christensen, J. M. Bouchard, F. Mou, R. Park, J. Baines, T. Haraguchi, and R. J. Roller (2007)
J. Virol. 81, 10792-10803
 |  Abstract »  |  Full Text »  |  PDF »

Human Biliverdin Reductase, a Previously Unknown Activator of Protein Kinase C betaII.

M. D. Maines, T. Miralem, N. Lerner-Marmarosh, J. Shen, and P. E. M. Gibbs (2007)
J. Biol. Chem. 282, 8110-8122
 |  Abstract »  |  Full Text »  |  PDF »

PKC {delta}-isoform translocation and enhancement of tonic contractions of gastrointestinal smooth muscle.

D. P. Poole and J. B. Furness (2007)
Am J Physiol Gastrointest Liver Physiol 292, G887-G898
 |  Abstract »  |  Full Text »  |  PDF »

RBCK1, a Protein Kinase CbetaI (PKCbetaI)-interacting Protein, Regulates PKCbeta-dependent Function.

A. Vallentin and D. Mochly-Rosen (2007)
J. Biol. Chem. 282, 1650-1657
 |  Abstract »  |  Full Text »  |  PDF »

Differential Effects of Systemic Ethanol Administration on Protein Kinase C{epsilon}, {gamma}, and beta Isoform Expression, Membrane Translocation, and Target Phosphorylation: Reversal by Chronic Ethanol Exposure.

S. Kumar, B. M. Lane, and A. L. Morrow (2006)
J. Pharmacol. Exp. Ther. 319, 1366-1375
 |  Abstract »  |  Full Text »  |  PDF »

Signaling Mechanisms in Ischemic Preconditioning: Interaction of PKC{epsilon} and MitoKATP in the Inner Membrane of Mitochondria.

H. Ardehali (2006)
Circ. Res. 99, 798-800
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Trans Fatty Acids and Coronary Heart Disease.

G. P. Zaloga, K. A. Harvey, W. Stillwell, and R. Siddiqui (2006)
Nutr Clin Pract 21, 505-512
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C {delta} ({delta}PKC)-Annexin V Interaction: A REQUIRED STEP IN {delta}PKC TRANSLOCATION AND FUNCTION.

V. Kheifets, R. Bright, K. Inagaki, D. Schechtman, and D. Mochly-Rosen (2006)
J. Biol. Chem. 281, 23218-23226
 |  Abstract »  |  Full Text »  |  PDF »

PDE7A1, a cAMP-specific Phosphodiesterase, Inhibits cAMP-dependent Protein Kinase by a Direct Interaction with C.

P. Han, P. Sonati, C. Rubin, and T. Michaeli (2006)
J. Biol. Chem. 281, 15050-15057
 |  Abstract »  |  Full Text »  |  PDF »

Epsilon protein kinase C as a potential therapeutic target for the ischemic heart.

K. Inagaki, E. Churchill, and D. Mochly-Rosen (2006)
Cardiovasc Res 70, 222-230
 |  Abstract »  |  Full Text »  |  PDF »

A Spatiotemporally Coordinated Cascade of Protein Kinase C Activation Controls Isoform-Selective Translocation..

A. Collazos, B. Diouf, N. C. Guerineau, C. Quittau-Prevostel, M. Peter, F. Coudane, F. Hollande, and D. Joubert (2006)
Mol. Cell. Biol. 26, 2247-2261
 |  Abstract »  |  Full Text »  |  PDF »

Pathways of matrix metalloproteinase induction in heart failure: Bioactive molecules and transcriptional regulation.

A. M. Deschamps and F. G. Spinale (2006)
Cardiovasc Res 69, 666-676
 |  Abstract »  |  Full Text »  |  PDF »

New Insights into Biliverdin Reductase Functions: Linking Heme Metabolism to Cell Signaling.

M. D. Maines (2005)
Physiology 20, 382-389
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Protein Kinase C in Cerebral Ischemic and Reperfusion Injury.

R. Bright and D. Mochly-Rosen (2005)
Stroke 36, 2781-2790
 |  Abstract »  |  Full Text »  |  PDF »

PKC-{varepsilon}-dependent survival signals in diabetic hearts.

A. Malhotra, R. Begley, B. P. S. Kang, I. Rana, J. Liu, G. Yang, D. Mochly-Rosen, and L. G. Meggs (2005)
Am J Physiol Heart Circ Physiol 289, H1343-H1350
 |  Abstract »  |  Full Text »  |  PDF »

Protein kinase C epsilon mediates angiotensin II-induced activation of {beta}1-integrins in cardiac fibroblasts.

P. Stawowy, C. Margeta, F. Blaschke, C. Lindschau, C. Spencer-Hansch, M. Leitges, G. Biagini, E. Fleck, and K. Graf (2005)
Cardiovasc Res 67, 50-59
 |  Abstract »  |  Full Text »  |  PDF »

Cell Wall Integrity Signaling in Saccharomyces cerevisiae.

D. E. Levin (2005)
Microbiol. Mol. Biol. Rev. 69, 262-291
 |  Abstract »  |  Full Text »  |  PDF »

Subcellular Alterations of Protein Kinase C Isozymes in the Rat Brain after Organophosphate Poisoning.

E. Bloch-Shilderman, T. Kadar, A. Levy, R. Sahar, I. Rabinovitz, and E. Gilat (2005)
J. Pharmacol. Exp. Ther. 313, 1082-1089
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of a UDP-glucuronosyltransferase regulates substrate specificity.

N. K. Basu, M. Kovarova, A. Garza, S. Kubota, T. Saha, P. S. Mitra, R. Banerjee, J. Rivera, and I. S. Owens (2005)
PNAS 102, 6285-6290
 |  Abstract »  |  Full Text »  |  PDF »

Opposing Effects of Protein Kinase C{alpha} and Protein Kinase C{epsilon} on Collagen Expression by Human Lung Fibroblasts Are Mediated via MEK/ERK and Caveolin-1 Signaling.

E. Tourkina, P. Gooz, J. Pannu, M. Bonner, D. Scholz, S. Hacker, R. M. Silver, M. Trojanowska, and S. Hoffman (2005)
J. Biol. Chem. 280, 13879-13887
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Selective Protein Kinase C Isozymes in Prostaglandin2{alpha}-Induced Ca2+ Signaling and Luteinizing Hormone-Induced Progesterone Accumulation in the Mid-Phase Bovine Corpus Luteum.

A. Sen, E. Choudhary, E. K. Inskeep, and J. A. Flores (2005)
Biol Reprod 72, 976-984
 |  Abstract »  |  Full Text »  |  PDF »

Epidermal and Hepatocyte Growth Factors, but Not Keratinocyte Growth Factor, Modulate Protein Kinase C{alpha} Translocation to the Plasma Membrane through 15(S)-Hydroxyeicosatetraenoic Acid Synthesis.

G. D. Sharma, P. Ottino, N. G. Bazan, and H. E. P. Bazan (2005)
J. Biol. Chem. 280, 7917-7924
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of cellular responses to insulin in a rat liver cell line. A role for PKC in insulin resistance.

L. Puljak, M. J Pagliassotti, Y. Wei, I. Qadri, V. Parameswara, V. Esser, J. G. Fitz, and G. Kilic (2005)
J. Physiol. 563, 471-482
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C {zeta} Is Required for Epidermal Growth Factor-Induced Chemotaxis of Human Breast Cancer Cells.

R. Sun, P. Gao, L. Chen, D. Ma, J. Wang, J. J. Oppenheim, and N. Zhang (2005)
Cancer Res. 65, 1433-1441
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Expression of the Epstein-Barr Virus BamHI-A Rightward Transcripts.

H. Chen, J. Huang, F. Y. Wu, G. Liao, L. Hutt-Fletcher, and S. D. Hayward (2005)
J. Virol. 79, 1724-1733
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Analysis Reveals Localization of Saccharomyces cerevisiae Protein Kinase C to Sites of Polarized Growth and Pkc1p Targeting to the Nucleus and Mitotic Spindle.

V. Denis and M. S. Cyert (2005)
Eukaryot. Cell 4, 36-45
 |  Abstract »  |  Full Text »  |  PDF »

Muscle ring finger protein-1 inhibits PKC{epsilon} activation and prevents cardiomyocyte hypertrophy.

R. Arya, V. Kedar, J. R. Hwang, H. McDonough, H.-H. Li, J. Taylor, and C. Patterson (2004)
J. Cell Biol. 167, 1147-1159
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of CCK-induced amylase release by PKC-{delta} in rat pancreatic acinar cells.

C. Li, X. Chen, and J. A. Williams (2004)
Am J Physiol Gastrointest Liver Physiol 287, G764-G771
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C {delta} Mediates Cerebral Reperfusion Injury In Vivo.

R. Bright, A. P. Raval, J. M. Dembner, M. A. Perez-Pinzon, G. K. Steinberg, M. A. Yenari, and D. Mochly-Rosen (2004)
J. Neurosci. 24, 6880-6888
 |  Abstract »  |  Full Text »  |  PDF »

RACK1 Regulates G1/S Progression by Suppressing Src Kinase Activity.

V. Mamidipudi, J. Zhang, K. C. Lee, and C. A. Cartwright (2004)
Mol. Cell. Biol. 24, 6788-6798
 |  Abstract »  |  Full Text »  |  PDF »

The receptor for activated C-kinase-I (RACK-I) anchors activated PKC-{beta} on melanosomes.

H.-Y. Park, H. Wu, C. E. Killoran, and B. A. Gilchrest (2004)
J. Cell Sci. 117, 3659-3668
 |  Abstract »  |  Full Text »  |  PDF »

Selective Inhibition of Protein Kinase C{beta}2 Prevents Acute Effects of High Glucose on Vascular Cell Adhesion Molecule-1 Expression in Human Endothelial Cells.

A. Kouroedov, M. Eto, H. Joch, M. Volpe, T. F. Luscher, and F. Cosentino (2004)
Circulation 110, 91-96
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Neutrophil Granule Protein Cathepsin G as a Novel Chemotactic Agonist for the G Protein-Coupled Formyl Peptide Receptor.

R. Sun, P. Iribarren, N. Zhang, Y. Zhou, W. Gong, E. H. Cho, S. Lockett, O. Chertov, F. Bednar, T. J. Rogers, et al. (2004)
J. Immunol. 173, 428-436
 |  Abstract »  |  Full Text »  |  PDF »

Direct association and translocation of PKC-{alpha} with calponin.

S. B. Patil, M. D. Pawar, and K. N. Bitar (2004)
Am J Physiol Gastrointest Liver Physiol 286, G954-G963
 |  Abstract »  |  Full Text »  |  PDF »

Role of the cytoskeleton in signaling networks.

G. Forgacs, S. H. Yook, P. A. Janmey, H. Jeong, and C. G. Burd (2004)
J. Cell Sci. 117, 2769-2775
 |  Abstract »  |  Full Text »  |  PDF »

State-specific Monoclonal Antibodies Identify an Intermediate State in Epsilon Protein Kinase C Activation.

M. C. Souroujon, L. Yao, H. Chen, G. Endemann, H. Khaner, V. Geeraert, D. Schechtman, A. S. Gordon, I. Diamond, and D. Mochly-Rosen (2004)
J. Biol. Chem. 279, 17617-17624
 |  Abstract »  |  Full Text »  |  PDF »

A Critical Intramolecular Interaction for Protein Kinase C{epsilon} Translocation.

D. Schechtman, M. L. Craske, V. Kheifets, T. Meyer, J. Schechtman, and D. Mochly-Rosen (2004)
J. Biol. Chem. 279, 15831-15840
 |  Abstract »  |  Full Text »  |  PDF »

Leukocyte-specific protein 1 targets the ERK/MAP kinase scaffold protein KSR and MEK1 and ERK2 to the actin cytoskeleton.

R. E. Harrison, B. A. Sikorski, and J. Jongstra (2004)
J. Cell Sci. 117, 2151-2157
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{gamma} Induces gp91phox Expression in Human Monocytes via Protein Kinase C-Dependent Phosphorylation of PU.1.

P. Mazzi, M. Donini, D. Margotto, F. Wientjes, and S. Dusi (2004)
J. Immunol. 172, 4941-4947
 |  Abstract »  |  Full Text »  |  PDF »

Protein kinase C plays an essential role in sildenafil-induced cardioprotection in rabbits.

A. Das, R. Ockaili, F. Salloum, and R. C. Kukreja (2004)
Am J Physiol Heart Circ Physiol 286, H1455-H1460
 |  Abstract »  |  Full Text »  |  PDF »

Ca2+-dependent Protein Kinase C Isoforms Induce Cholestasis in Rat Liver.

R. Kubitz, N. Saha, T. Kuhlkamp, S. Dutta, S. vom Dahl, M. Wettstein, and D. Haussinger (2004)
J. Biol. Chem. 279, 10323-10330
 |  Abstract »  |  Full Text »  |  PDF »

Centrosomal Anchoring of Protein Kinase C {beta}II by Pericentrin Controls Microtubule Organization, Spindle Function, and Cytokinesis.

D. Chen, A. Purohit, E. Halilovic, S. J. Doxsey, and A. C. Newton (2004)
J. Biol. Chem. 279, 4829-4839
 |  Abstract »  |  Full Text »  |  PDF »

Primary and Secondary Signaling Pathways in Early Preconditioning That Converge on the Mitochondria to Produce Cardioprotection.

E. Murphy (2004)
Circ. Res. 94, 7-16
 |  Abstract »  |  Full Text »  |  PDF »

{alpha}3{beta}1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTP{micro} expression and cell-cell adhesion.

N. Chattopadhyay, Z. Wang, L. K. Ashman, S. M. Brady-Kalnay, and J. A. Kreidberg (2003)
J. Cell Biol. 163, 1351-1362
 |  Abstract »  |  Full Text »  |  PDF »

Alterations in rat coronary vasoreactivity and vascular protein kinase C isoforms in Type 1 diabetes.

M. M. Tickerhoof, P A. Farrell, and D. H. Korzick (2003)
Am J Physiol Heart Circ Physiol 285, H2694-H2703
 |  Abstract »  |  Full Text »  |  PDF »

TRUSS, a Novel Tumor Necrosis Factor Receptor 1 Scaffolding Protein That Mediates Activation of the Transcription Factor NF-{kappa}B.

S. M. Soond, J. L. Terry, J. D. Colbert, and D. W. H. Riches (2003)
Mol. Cell. Biol. 23, 8334-8344
 |  Abstract »  |  Full Text »  |  PDF »

Rapid Association of Protein Kinase C-{epsilon} with Insulin Granules Is Essential for Insulin Exocytosis.

C. F. Mendez, I. B. Leibiger, B. Leibiger, M. Hoy, J. Gromada, P.-O. Berggren, and A. M. Bertorello (2003)
J. Biol. Chem. 278, 44753-44757
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Protein Kinase C-{delta} in Mouse Oocytes Throughout Meiotic Maturation and Following Egg Activation.

M. M. Viveiros, M. O'Brien, K. Wigglesworth, and J. J. Eppig (2003)
Biol Reprod 69, 1494-1499
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Novel Signaling Complexes by Functional Proteomics.

P. Ping (2003)
Circ. Res. 93, 595-603
 |  Abstract »  |  Full Text »  |  PDF »

PICK1, an Anchoring Protein That Specifically Targets Protein Kinase C{alpha} to Mitochondria Selectively upon Serum Stimulation in NIH 3T3 Cells.

W.-L. Wang, S.-F. Yeh, Y.-I Chang, S.-F. Hsiao, W.-N. Lian, C.-H. Lin, C.-Y. F. Huang, and W.-J. Lin (2003)
J. Biol. Chem. 278, 37705-37712
 |  Abstract »  |  Full Text »  |  PDF »

Additive Protection of the Ischemic Heart Ex Vivo by Combined Treatment With {delta}-Protein Kinase C Inhibitor and {epsilon}-Protein Kinase C Activator.

K. Inagaki, H. S. Hahn, G. W. Dorn II, and D. Mochly-Rosen (2003)
Circulation 108, 869-875
 |  Abstract »  |  Full Text »  |  PDF »

Microtubule-dependent PKC-{alpha} localization in A7r5 smooth muscle cells.

A. C. Dykes, M. E. Fultz, M. L. Norton, and G. L. Wright (2003)
Am J Physiol Cell Physiol 285, C76-C87
 |  Abstract »  |  Full Text »  |  PDF »

Four-dimensional organization of protein kinase signaling cascades: the roles of diffusion, endocytosis and molecular motors.

B. N Kholodenko (2003)
J. Exp. Biol. 206, 2073-2082
 |  Abstract »  |  Full Text »  |  PDF »

A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C.

J. D. Violin, J. Zhang, R. Y. Tsien, and A. C. Newton (2003)
J. Cell Biol. 161, 899-909
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of the Tyrosine Kinase Pyk2 with the N-Methyl-D-aspartate Receptor Complex via the Src Homology 3 Domains of PSD-95 and SAP102.

G. K. Seabold, A. Burette, I. A. Lim, R. J. Weinberg, and J. W. Hell (2003)
J. Biol. Chem. 278, 15040-15048
 |  Abstract »  |  Full Text »  |  PDF »

Ca2+-independent Protein Kinase Cs Mediate Heterologous Desensitization of Leukocyte Chemokine Receptors by Opioid Receptors.

N. Zhang, D. Hodge, T. J. Rogers, and J. J. Oppenheim (2003)
J. Biol. Chem. 278, 12729-12736
 |  Abstract »  |  Full Text »  |  PDF »

Role of PKC in autocrine regulation of rat ventricular K+ currents by angiotensin and endothelin.

Y. Shimoni and X.-F. Liu (2003)
Am J Physiol Heart Circ Physiol 284 , H1168-H1181
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Protein Kinase C Isozymes Responsible for the Phosphorylation of Photoreceptor-specific RGS9-1 at Ser475.

I. Sokal, G. Hu, Y. Liang, M. Mao, T. G. Wensel, and K. Palczewski (2003)
J. Biol. Chem. 278, 8316-8325
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of Rubella Virus Capsid Regulates Its RNA Binding Activity and Virus Replication.

L. M. J. Law, J. C. Everitt, M. D. Beatch, C. F. B. Holmes, and T. C. Hobman (2003)
J. Virol. 77, 1764-1771
 |  Abstract »  |  Full Text »  |  PDF »

EGF-Induced ERK Phosphorylation Independent of PKC Isozymes in Human Corneal Epithelial Cells.

K.-P. Xu, D. A. Dartt, and F.-S. X. Yu (2002)
Invest. Ophthalmol. Vis. Sci. 43, 3673-3679
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of volume-sensitive outwardly rectifying anion channels in pulmonary arterial smooth muscle cells by PKC.

J. Zhong, G.-X. Wang, W. J. Hatton, I. A. Yamboliev, M. P. Walsh, and J. R. Hume (2002)
Am J Physiol Cell Physiol 283, C1627-C1636
 |  Abstract »  |  Full Text »  |  PDF »

Ischemic Protection and Myofibrillar Cardiomyopathy: Dose-Dependent Effects of In Vivo {delta}PKC Inhibition.

H. S. Hahn, M. G. Yussman, T. Toyokawa, Y. Marreez, T. J. Barrett, K. C. Hilty, H. Osinska, J. Robbins, and G. W. Dorn II (2002)
Circ. Res. 91, 741-748
 |  Abstract »  |  Full Text »  |  PDF »

Interplay between Calcium, Diacylglycerol, and Phosphorylation in the Spatial and Temporal Regulation of PKCalpha -GFP.

A. Tanimura, A. Nezu, T. Morita, N. Hashimoto, and Y. Tojyo (2002)
J. Biol. Chem. 277, 29054-29062
 |  Abstract »  |  Full Text »  |  PDF »

Ethanol Induces Gene Expression via Nuclear Compartmentalization of Receptor for Activated C Kinase 1.

D.-Y. He, A. J. Vagts, R. Yaka, and D. Ron (2002)
Mol. Pharmacol. 62, 272-280
 |  Abstract »  |  Full Text »  |  PDF »

Actin Capping Protein: An Essential Element in Protein Kinase Signaling to the Myofilaments.

W. G. Pyle, M. C. Hart, J. A. Cooper, M. P. Sumandea, P. P. de Tombe, and R. J. Solaro (2002)
Circ. Res. 90, 1299-1306
 |  Abstract »  |  Full Text »  |  PDF »

Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKCepsilon knockout mouse hearts.

Z.-Q. Jin, H.-Z. Zhou, P. Zhu, N. Honbo, D. Mochly-Rosen, R. O. Messing, E. J. Goetzl, J. S. Karliner, and M. O. Gray (2002)
Am J Physiol Heart Circ Physiol 282, H1970-H1977
 |  Abstract »  |  Full Text »  |  PDF »

Sequential activation of individual PKC isozymes in integrin-mediated muscle cell spreading: a role for MARCKS in an integrin signaling pathway.

M.-H. Disatnik, S. C. Boutet, C. H. Lee, D. Mochly-Rosen, and T. A. Rando (2002)
J. Cell Sci. 115, 2151-2163
 |  Abstract »  |  Full Text »  |  PDF »

Fas activation opposes PMA-stimulated changes in the localization of PKC{delta}: a mechanism for reducing neutrophil adhesion to endothelial cells.

B. Hendey, C. L. Zhu, and S. Greenstein (2002)
J. Leukoc. Biol. 71, 863-870
 |  Abstract »  |  Full Text »  |  PDF »

SHIP Negatively Regulates IgE + Antigen-Induced IL-6 Production in Mast Cells by Inhibiting NF-{kappa}B Activity.

J. Kalesnikoff, N. Baur, M. Leitges, M. R. Hughes, J. E. Damen, M. Huber, and G. Krystal (2002)
J. Immunol. 168, 4737-4746
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide (NO) Induces Nitration of Protein Kinase Cepsilon (PKCepsilon ), Facilitating PKCepsilon Translocation via Enhanced PKCepsilon -RACK2 Interactions. A NOVEL MECHANISM OF NO-TRIGGERED ACTIVATION OF PKCepsilon.

Z. Balafanova, R. Bolli, J. Zhang, Y. Zheng, J. M. Pass, A. Bhatnagar, X.-L. Tang, O. Wang, E. Cardwell, and P. Ping (2002)
J. Biol. Chem. 277, 15021-15027
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Molecular Dynamics Characterization of the C2 Domain of Protein Kinase Cbeta.

L. Banci, G. Cavallaro, V. Kheifets, and D. Mochly-Rosen (2002)
J. Biol. Chem. 277, 12988-12997
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PKC{alpha} regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2).

J. C. Braz, O. F. Bueno, L. J. De Windt, and J. D. Molkentin (2002)
J. Cell Biol. 156, 905-919
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Mechanotransduction through the cytoskeleton.

Y. Shafrir and G. Forgacs (2002)
Am J Physiol Cell Physiol 282, C479-C486
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The role of protein kinase C-delta in PTH stimulation of IGF-binding protein-5 mRNA in UMR-106-01 cells.

M. S. Erclik and J. Mitchell (2002)
Am J Physiol Endocrinol Metab 282, E534-E541
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An A-kinase anchoring protein is required for Protein kinase A regulatory subunit localization and morphology of actin structures during oogenesis in Drosophila.

S. M. Jackson and C. A. Berg (2002)
Development 129, 4423-4433
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Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering.

J. Zhang, Y. Ma, S. S. Taylor, and R. Y. Tsien (2001)
PNAS 98, 14997-15002
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Involvement of Protein Kinase C in TNF{alpha} Regulation of Trabecular Matrix Metalloproteinases and TIMPs.

J. P. Alexander and T. S. Acott (2001)
Invest. Ophthalmol. Vis. Sci. 42, 2831-2838
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Evidence for functional role of epsilon PKC isozyme in the regulation of cardiac Na+ channels.

G.-Q. Xiao, Y. Qu, Z.-Q. Sun, D. Mochly-Rosen, and M. Boutjdir (2001)
Am J Physiol Cell Physiol 281, C1477-C1486
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Mechanisms and Physiological Significance of the Cholinergic Control of Pancreatic {beta}-Cell Function.

P. Gilon and J.-C. Henquin (2001)
Endocr. Rev. 22, 565-604
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Protein Kinase Activity Is Central to Rat Germ Cell Apoptosis Induced by Methoxyacetic Acid.

T. Jindo, R. N. Wine, L.-H. Li, and R. E. Chapin (2001)
Toxicol Pathol 29, 607-616
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Serotonin Receptors Modulate GABAA Receptor Channels through Activation of Anchored Protein Kinase C in Prefrontal Cortical Neurons.

J. Feng, X. Cai, J. Zhao, and Z. Yan (2001)
J. Neurosci. 21, 6502-6511
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Angiotensin II Promotes Glucose-Induced Activation of Cardiac Protein Kinase C Isozymes and Phosphorylation of Troponin I.

A. Malhotra, B. P.S. Kang, S. Cheung, D. Opawumi, and L. G. Meggs (2001)
Diabetes 50, 1918-1926
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Evidence for a role of protein kinase C in FGF signal transduction in the developing chick limb bud.

H.-C. Lu, E. C. Swindell, W. D. Sierralta, G. Eichele, and C. Thaller (2001)
Development 128, 2451-2460
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PKC{epsilon} activation induces dichotomous cardiac phenotypes and modulates PKC{epsilon}-RACK interactions and RACK expression.

J. M. Pass, Y. Zheng, W. B. Wead, J. Zhang, R. C. X. Li, R. Bolli, and P. Ping (2001)
Am J Physiol Heart Circ Physiol 280, H946-H955
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Transgenic incorporation of skeletal TnT into cardiac myofilaments blunts PKC-mediated depression of force.

D. E. Montgomery, M. Chandra, Q.-Q. Huang, J.-P. Jin, and R. J. Solaro (2001)
Am J Physiol Heart Circ Physiol 280, H1011-H1018
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