Science 14 April 1995: Vol. 268. no. 5208, pp. 225 - 232 DOI: 10.1126/science.7716513

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Articles

Notch1 Signaling in FIZZ1 Induction of Myofibroblast Differentiation.

T. Liu, B. Hu, Y. Y. Choi, M. Chung, M. Ullenbruch, H. Yu, J. B. Lowe, and S. H. Phan (2009)
Am. J. Pathol. 174, 1745-1755
 |  Abstract »  |  Full Text »  |  PDF »

Simvastatin enhances bone marrow stromal cell differentiation into endothelial cells via notch signaling pathway.

J. Xu, X. Liu, J. Chen, A. Zacharek, X. Cui, S. Savant-Bhonsale, Z. Liu, and M. Chopp (2009)
Am J Physiol Cell Physiol 296, C535-C543
 |  Abstract »  |  Full Text »  |  PDF »

Structural and Mechanistic Insights into Lunatic Fringe from a Kinetic Analysis of Enzyme Mutants.

K. B. Luther, H. Schindelin, and R. S. Haltiwanger (2009)
J. Biol. Chem. 284, 3294-3305
 |  Abstract »  |  Full Text »  |  PDF »

Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population.

B. Zhang, R. Liu, D. Shi, X. Liu, Y. Chen, X. Dou, X. Zhu, C. Lu, W. Liang, L. Liao, et al. (2009)
Blood 113, 46-57
 |  Abstract »  |  Full Text »  |  PDF »

Control of the adaptive response of the heart to stress via the Notch1 receptor pathway.

A. Croquelois, A. A. Domenighetti, M. Nemir, M. Lepore, N. Rosenblatt-Velin, F. Radtke, and T. Pedrazzini (2008)
J. Exp. Med. 205, 3173-3185
 |  Abstract »  |  Full Text »  |  PDF »

Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon.

D. Kawaguchi, T. Yoshimatsu, K. Hozumi, and Y. Gotoh (2008)
Development 135, 3849-3858
 |  Abstract »  |  Full Text »  |  PDF »

Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis.

A. Kawaguchi, T. Ikawa, T. Kasukawa, H. R. Ueda, K. Kurimoto, M. Saitou, and F. Matsuzaki (2008)
Development 135, 3113-3124
 |  Abstract »  |  Full Text »  |  PDF »

Cell-type-specific transcription of prospero is controlled by combinatorial signaling in the Drosophila eye.

T. Hayashi, C. Xu, and R. W. Carthew (2008)
Development 135, 2787-2796
 |  Abstract »  |  Full Text »  |  PDF »

Ascidian Sperm Glycosylphosphatidylinositol-anchored CRISP-like Protein as a Binding Partner for an Allorecognizable Sperm Receptor on the Vitelline Coat.

S. Urayama, Y. Harada, Y. Nakagawa, S. Ban, M. Akasaka, N. Kawasaki, and H. Sawada (2008)
J. Biol. Chem. 283, 21725-21733
 |  Abstract »  |  Full Text »  |  PDF »

Plasma concentration of SCUBE1, a novel platelet protein, is elevated in patients with acute coronary syndrome and ischemic stroke..

D.-F. Dai, P. Thajeb, C.-F. Tu, F.-T. Chiang, C.-H. Chen, R.-B. Yang, and J.-J. Chen (2008)
J. Am. Coll. Cardiol. 51, 2173-2180
 |  Abstract »  |  Full Text »  |  PDF »

Soluble Jagged1 Attenuates Lateral Inhibition, Allowing for the Clonal Expansion of Neural Crest Stem Cells.

G. N. Nikopoulos, M. Duarte, C. J. Kubu, S. Bellum, R. Friesel, T. Maciag, I. Prudovsky, and J. M. Verdi (2007)
Stem Cells 25, 3133-3142
 |  Abstract »  |  Full Text »  |  PDF »

Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes.

A. Li, Z. Xie, Y. Dong, K. M. McKay, M. L. McKee, and R. E. Tanzi (2007)
Hum. Mol. Genet. 16, 2626-2639
 |  Abstract »  |  Full Text »  |  PDF »

Mammalian NOTCH-1 Activates beta1 Integrins via the Small GTPase R-Ras.

P. S. Hodkinson, Paul. A. Elliott, Y. Lad, B. J. McHugh, A. C. MacKinnon, C. Haslett, and T. Sethi (2007)
J. Biol. Chem. 282, 28991-29001
 |  Abstract »  |  Full Text »  |  PDF »

Viable Mice with Compound Mutations in the Wnt/Dvl Pathway Antagonists nkd1 and nkd2.

S. Zhang, T. Cagatay, M. Amanai, M. Zhang, J. Kline, D. H. Castrillon, R. Ashfaq, O. K. Oz, and K. A. Wharton Jr. (2007)
Mol. Cell. Biol. 27, 4454-4464
 |  Abstract »  |  Full Text »  |  PDF »

Mastermind-1 is required for Notch signal-dependent steps in lymphocyte development in vivo.

T. Oyama, K. Harigaya, A. Muradil, K. Hozumi, S. Habu, H. Oguro, A. Iwama, K. Matsuno, R. Sakamoto, M. Sato, et al. (2007)
PNAS 104, 9764-9769
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Notch Signaling Induces Neural Differentiation in Ewing Sarcoma.

F. Baliko, T. Bright, R. Poon, B. Cohen, S. E. Egan, and B. A. Alman (2007)
Am. J. Pathol. 170, 1686-1694
 |  Abstract »  |  Full Text »  |  PDF »

Pref-1 (Preadipocyte Factor 1) Activates the MEK/Extracellular Signal-Regulated Kinase Pathway To Inhibit Adipocyte Differentiation.

K.-A. Kim, J.-H. Kim, Y. Wang, and H. S. Sul (2007)
Mol. Cell. Biol. 27, 2294-2308
 |  Abstract »  |  Full Text »  |  PDF »

Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros.

Y. Liu, N. Pathak, A. Kramer-Zucker, and I. A. Drummond (2007)
Development 134, 1111-1122
 |  Abstract »  |  Full Text »  |  PDF »

Notch1 Augments Intracellular Trafficking of Adeno-Associated Virus Type 2.

C. Ren, A. F. White, and S. Ponnazhagan (2007)
J. Virol. 81, 2069-2073
 |  Abstract »  |  Full Text »  |  PDF »

Notch-1 regulates pulmonary neuroendocrine cell differentiation in cell lines and in transgenic mice.

L. Shan, J. C. Aster, J. Sklar, and M. E. Sunday (2007)
Am J Physiol Lung Cell Mol Physiol 292, L500-L509
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Histamine on Immunophenotype and Notch Signaling in Human HL-60 Leukemia Cells..

L. M. Yu, D. X. Chen, Q. X. Zhou, N. Fang, and Z. L. Liu (2006)
Experimental Biology and Medicine 231, 1633-1637
 |  Abstract »  |  Full Text »  |  PDF »

Concise Review: Notch Signaling in Stem Cell Systems.

S. Chiba (2006)
Stem Cells 24, 2437-2447
 |  Abstract »  |  Full Text »  |  PDF »

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

L. S. Tang, H. M. Alger, and F. A. Pereira (2006)
Development 133, 3683-3693
 |  Abstract »  |  Full Text »  |  PDF »

Up-Regulation of Endothelial Delta-like 4 Expression Correlates with Vessel Maturation in Bladder Cancer..

N. S. Patel, M. S. Dobbie, M. Rochester, G. Steers, R. Poulsom, K. Le Monnier, D. W. Cranston, J.-L. Li, and A. L. Harris (2006)
Clin. Cancer Res. 12, 4836-4844
 |  Abstract »  |  Full Text »  |  PDF »

The Murine Ortholog of Notchless, a Direct Regulator of the Notch Pathway in Drosophila melanogaster, Is Essential for Survival of Inner Cell Mass Cells..

S. Cormier, S. Le Bras, C. Souilhol, S. Vandormael-Pournin, B. Durand, C. Babinet, P. Baldacci, and M. Cohen-Tannoudji (2006)
Mol. Cell. Biol. 26, 3541-3549
 |  Abstract »  |  Full Text »  |  PDF »

Secretion of the Notch-1 Abeta-like Peptide during Notch Signaling.

M. Okochi, A. Fukumori, J. Jiang, N. Itoh, R. Kimura, H. Steiner, C. Haass, S. Tagami, and M. Takeda (2006)
J. Biol. Chem. 281, 7890-7898
 |  Abstract »  |  Full Text »  |  PDF »

Recent insights into the role of Notch signaling in tumorigenesis.

K. G. Leong and A. Karsan (2006)
Blood 107, 2223-2233
 |  Abstract »  |  Full Text »  |  PDF »

Notch 1 Overexpression Inhibits Osteoblastogenesis by Suppressing Wnt/beta-Catenin but Not Bone Morphogenetic Protein Signaling.

V. Deregowski, E. Gazzerro, L. Priest, S. Rydziel, and E. Canalis (2006)
J. Biol. Chem. 281, 6203-6210
 |  Abstract »  |  Full Text »  |  PDF »

Par-1 kinase establishes cell polarity and functions in Notch signaling in the Drosophila embryo.

J. Bayraktar, D. Zygmunt, and R. W. Carthew (2006)
J. Cell Sci. 119, 711-721
 |  Abstract »  |  Full Text »  |  PDF »

Gene Regulatory Networks and the Evolution of Animal Body Plans.

E. H. Davidson and D. H. Erwin (2006)
Science 311, 796-800
 |  Abstract »  |  Full Text »  |  PDF »

NPC1 Gene Deficiency Leads to Lack of Neural Stem Cell Self-Renewal and Abnormal Differentiation Through Activation of p38 Mitogen-Activated Protein Kinase Signaling.

S.-R. Yang, S.-J. Kim, K.-H. Byun, B. Hutchinson, B.-H. Lee, M. Michikawa, Y.-S. Lee, and K.-S. Kang (2006)
Stem Cells 24, 292-298
 |  Abstract »  |  Full Text »  |  PDF »

Role of 14-3-3{gamma} in FE65-dependent Gene Transactivation Mediated by the Amyloid {beta}-Protein Precursor Cytoplasmic Fragment.

A. Sumioka, S. Nagaishi, T. Yoshida, A. Lin, M. Miura, and T. Suzuki (2005)
J. Biol. Chem. 280, 42364-42374
 |  Abstract »  |  Full Text »  |  PDF »

Up-regulation of Delta-like 4 Ligand in Human Tumor Vasculature and the Role of Basal Expression in Endothelial Cell Function.

N. S. Patel, J.-L. Li, D. Generali, R. Poulsom, D. W. Cranston, and A. L. Harris (2005)
Cancer Res. 65, 8690-8697
 |  Abstract »  |  Full Text »  |  PDF »

A novel role for Notch ligand Delta-1 as a regulator of human Langerhans cell development from blood monocytes.

N. Hoshino, N. Katayama, T. Shibasaki, K. Ohishi, J. Nishioka, M. Masuya, Y. Miyahara, M. Hayashida, D. Shimomura, T. Kato, et al. (2005)
J. Leukoc. Biol. 78, 921-929
 |  Abstract »  |  Full Text »  |  PDF »

Mind Bomb-2 Is an E3 Ligase for Notch Ligand.

B.-K. Koo, K.-J. Yoon, K.-W. Yoo, H.-S. Lim, R. Song, J.-H. So, C.-H. Kim, and Y.-Y. Kong (2005)
J. Biol. Chem. 280, 22335-22342
 |  Abstract »  |  Full Text »  |  PDF »

Charlatan, a Zn-finger transcription factor, establishes a novel level of regulation of the proneural achaete/scute genes of Drosophila.

L. M. Escudero, E. Caminero, K. L. Schulze, H. J. Bellen, and J. Modolell (2005)
Development 132, 1211-1222
 |  Abstract »  |  Full Text »  |  PDF »

Self/nonself recognition in ascidian fertilization: Vitelline coat protein HrVC70 is a candidate allorecognition molecule.

H. Sawada, E. Tanaka, S. Ban, C. Yamasaki, J. Fujino, K. Ooura, Y. Abe, K.-i. Matsumoto, and H. Yokosawa (2004)
PNAS 101, 15615-15620
 |  Abstract »  |  Full Text »  |  PDF »

Constitutively active Notch4 promotes early human hematopoietic progenitor cell maintenance while inhibiting differentiation and causes lymphoid abnormalities in vivo.

S. M. Vercauteren and H. J. Sutherland (2004)
Blood 104, 2315-2322
 |  Abstract »  |  Full Text »  |  PDF »

Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling.

S. Hitoshi, R. M. Seaberg, C. Koscik, T. Alexson, S. Kusunoki, I. Kanazawa, S. Tsuji, and D. van der Kooy (2004)
Genes & Dev. 18, 1806-1811
 |  Abstract »  |  Full Text »  |  PDF »

The Drosophila Receptor Guanylyl Cyclase Gyc76C Is Required for Semaphorin-1a-Plexin A-Mediated Axonal Repulsion.

J. C. Ayoob, H.-H. Yu, J. R. Terman, and A. L. Kolodkin (2004)
J. Neurosci. 24, 6639-6649
 |  Abstract »  |  Full Text »  |  PDF »

Notch signaling in Drosophila long-term memory formation.

X. Ge, F. Hannan, Z. Xie, C. Feng, T. Tully, H. Zhou, Z. Xie, and Y. Zhong (2004)
PNAS 101, 10172-10176
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of Notch signaling in hippocampal synaptic plasticity.

Y. Wang, S. L. Chan, L. Miele, P. J. Yao, J. Mackes, D. K. Ingram, M. P. Mattson, and K. Furukawa (2004)
PNAS 101, 9458-9462
 |  Abstract »  |  Full Text »  |  PDF »

Single nucleotide polymorphism in the low-density lipoprotein receptor is associated with a threefold risk of stroke: A case-control and prospective study.

R. Frikke-Schmidt, B. G. Nordestgaard, P. Schnohr, and A. Tybjaerg-Hansen (2004)
Eur. Heart J. 25, 943-951
 |  Abstract »  |  Full Text »  |  PDF »

Functional diversity of notch family genes in fetal lung development.

Y. Kong, J. Glickman, M. Subramaniam, A. Shahsafaei, K. P. Allamneni, J. C. Aster, J. Sklar, and M. E. Sunday (2004)
Am J Physiol Lung Cell Mol Physiol 286, L1075-L1083
 |  Abstract »  |  Full Text »  |  PDF »

Evidence That C Promoter-binding Factor 1 Binding Is Required for Notch-1-mediated Repression of Activator Protein-1.

J. Chu and E. H. Bresnick (2004)
J. Biol. Chem. 279, 12337-12345
 |  Abstract »  |  Full Text »  |  PDF »

RING1 inhibits transactivation of RBP-J by Notch through interaction with LIM protein KyoT2.

H. Qin, J. Wang, Y. Liang, Y. Taniguchi, K. Tanigaki, and H. Han (2004)
Nucleic Acids Res. 32, 1492-1501
 |  Abstract »  |  Full Text »  |  PDF »

Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions.

J. Wang, C. Shiels, P. Sasieni, P. J. Wu, S. A. Islam, P. S. Freemont, and D. Sheer (2004)
J. Cell Biol. 164, 515-526
 |  Abstract »  |  Full Text »  |  PDF »

Notch Signaling and ERK Activation Are Important for the Osteomimetic Properties of Prostate Cancer Bone Metastatic Cell Lines.

M. Zayzafoon, S. A. Abdulkadir, and J. M. McDonald (2004)
J. Biol. Chem. 279, 3662-3670
 |  Abstract »  |  Full Text »  |  PDF »

No Evidence for an Association Between Common Nonsynonymous Polymorphisms in Delta and Bristle Number Variation in Natural and Laboratory Populations of Drosophila melanogaster.

A. Genissel, T. Pastinen, A. Dowell, T. F. C. Mackay, and A. D. Long (2004)
Genetics 166, 291-306
 |  Abstract »  |  Full Text »  |  PDF »

Echinoid facilitates Notch pathway signalling during Drosophila neurogenesis through functional interaction with Delta.

E. L. Rawlins, B. Lovegrove, and A. P. Jarman (2003)
Development 130, 6475-6484
 |  Abstract »  |  Full Text »  |  PDF »

echinoid mutants exhibit neurogenic phenotypes and show synergistic interactions with the Notch signaling pathway.

A. Ahmed, S. Chandra, M. Magarinos, and H. Vaessin (2003)
Development 130, 6295-6304
 |  Abstract »  |  Full Text »  |  PDF »

Echinoid synergizes with the Notch signaling pathway in Drosophila mesothorax bristle patterning.

L. M. Escudero, S.-Y. Wei, W.-H. Chiu, J. Modolell, and J.-C. Hsu (2003)
Development 130, 6305-6316
 |  Abstract »  |  Full Text »  |  PDF »

Notch-Mediated Restoration of Regenerative Potential to Aged Muscle.

I. M. Conboy, M. J. Conboy, G. M. Smythe, and T. A. Rando (2003)
Science 302, 1575-1577
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells.

E. S. Yvon, S. Vigouroux, R. F. Rousseau, E. Biagi, P. Amrolia, G. Dotti, H.-J. Wagner, and M. K. Brenner (2003)
Blood 102, 3815-3821
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Antigen-Specific Regulatory T Cells following Overexpression of a Notch Ligand by Human B Lymphocytes.

S. Vigouroux, E. Yvon, H.-J. Wagner, E. Biagi, G. Dotti, U. Sili, C. Lira, C. M. Rooney, and M. K. Brenner (2003)
J. Virol. 77, 10872-10880
 |  Abstract »  |  Full Text »  |  PDF »

{gamma}-Secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney.

H.-T. Cheng, J. H. Miner, M. Lin, M. G. Tansey, K. Roth, and R. Kopan (2003)
Development 130, 5031-5042
 |  Abstract »  |  Full Text »  |  PDF »

neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions.

T. Sasamura, N. Sasaki, F. Miyashita, S. Nakao, H. O. Ishikawa, M. Ito, M. Kitagawa, K. Harigaya, E. Spana, D. Bilder, et al. (2003)
Development 130, 4785-4795
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced gene activation by Notch and BMP signaling cross-talk.

T. Takizawa, W. Ochiai, K. Nakashima, and T. Taga (2003)
Nucleic Acids Res. 31, 5723-5731
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation by Glycogen Synthase Kinase-3{beta} Down-regulates Notch Activity, a Link for Notch and Wnt Pathways.

L. Espinosa, J. Ingles-Esteve, C. Aguilera, and A. Bigas (2003)
J. Biol. Chem. 278, 32227-32235
 |  Abstract »  |  Full Text »  |  PDF »

SFRP1 modulates retina cell differentiation through a {beta}-catenin-independent mechanism.

P. Esteve, F. Trousse, J. Rodriguez, and P. Bovolenta (2003)
J. Cell Sci. 116, 2471-2481
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Models in Applied Physiology: Invited Review: Effect of oxygen deprivation on cell cycle activity: a profile of delay and arrest.

R. M. Douglas and G. G. Haddad (2003)
J Appl Physiol 94, 2068-2083
 |  Abstract »  |  Full Text »  |  PDF »

Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process.

L. Grandbarbe, J. Bouissac, M. Rand, M. Hrabe de Angelis, S. Artavanis-Tsakonas, and E. Mohier (2003)
Development 130, 1391-1402
 |  Abstract »  |  Full Text »  |  PDF »

Context-dependent utilization of Notch activity in Drosophila glial determination.

Y. Umesono, Y. Hiromi, and Y. Hotta (2003)
Development 129, 2391-2399
 |  Abstract »  |  Full Text »  |  PDF »

A positive role for Patched-Smoothened signaling in promoting cell proliferation during normal head development in Drosophila.

B. V. Shyamala and K. M. Bhat (2003)
Development 129, 1839-1847
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling.

K. Matsuno, M. Ito, K. Hori, F. Miyashita, S. Suzuki, N. Kishi, S. Artavanis-Tsakonas, and H. Okano (2003)
Development 129, 1049-1059
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Notch1 and Dll4 by Vascular Endothelial Growth Factor in Arterial Endothelial Cells: Implications for Modulating Arteriogenesis and Angiogenesis.

Z.-J. Liu, T. Shirakawa, Y. Li, A. Soma, M. Oka, G. P. Dotto, R. M. Fairman, O. C. Velazquez, and M. Herlyn (2003)
Mol. Cell. Biol. 23, 14-25
 |  Abstract »  |  Full Text »

Regulation of Hematopoietic Stem Cell Self-Renewal.

T. Reya (2003)
Recent Prog. Horm. Res. 58, 283-295
 |  Abstract »  |  Full Text »  |  PDF »

Node and midline defects are associated with left-right development in Delta1 mutant embryos.

G. K. H. Przemeck, U. Heinzmann, J. Beckers, and M. Hrabe de Angelis (2003)
Development 130, 3-13
 |  Abstract »  |  Full Text »  |  PDF »

Identification of New Human Mastermind Proteins Defines a Family That Consists of Positive Regulators for Notch Signaling.

S.-E. Lin, T. Oyama, T. Nagase, K. Harigaya, and M. Kitagawa (2002)
J. Biol. Chem. 277, 50612-50620
 |  Abstract »  |  Full Text »  |  PDF »

Down-regulation of Delta by proteolytic processing.

K. Mishra-Gorur, M. D. Rand, B. Perez-Villamil, and S. Artavanis-Tsakonas (2002)
J. Cell Biol. 159, 313-324
 |  Abstract »  |  Full Text »  |  PDF »

Notch1 control of oligodendrocyte differentiation in the spinal cord.

S. Genoud, C. Lappe-Siefke, S. Goebbels, F. Radtke, M. Aguet, S. S. Scherer, U. Suter, K.-A. Nave, and N. Mantei (2002)
J. Cell Biol. 158, 709-718
 |  Abstract »  |  Full Text »  |  PDF »

The gamma Secretase-generated Carboxyl-terminal Domain of the Amyloid Precursor Protein Induces Apoptosis via Tip60 in H4 Cells.

A. Kinoshita, C. M. Whelan, O. Berezovska, and B. T. Hyman (2002)
J. Biol. Chem. 277, 28530-28536
 |  Abstract »  |  Full Text »  |  PDF »

Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision.

H. Han, K. Tanigaki, N. Yamamoto, K. Kuroda, M. Yoshimoto, T. Nakahata, K. Ikuta, and T. Honjo (2002)
Int. Immunol. 14, 637-645
 |  Abstract »  |  Full Text »  |  PDF »

Signalling in Plant Lateral Organ Development.

J. F. Golz and A. Hudson (2002)
PLANT CELL 14, S277-288
 |  Full Text »  |  PDF »

Regulated Cationic Channel Function in Xenopus Oocytes Expressing Drosophila Big Brain.

G. M. Yanochko and A. J. Yool (2002)
J. Neurosci. 22, 2530-2540
 |  Abstract »  |  Full Text »  |  PDF »

Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells.

S. Hitoshi, T. Alexson, V. Tropepe, D. Donoviel, A. J. Elia, J. S. Nye, R. A. Conlon, T. W. Mak, A. Bernstein, and D. van der Kooy (2002)
Genes & Dev. 16, 846-858
 |  Abstract »  |  Full Text »  |  PDF »

Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome.

S. Stier, T. Cheng, D. Dombkowski, N. Carlesso, and D. T. Scadden (2002)
Blood 99, 2369-2378
 |  Abstract »  |  Full Text »  |  PDF »

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.

D. Bellavia, A. F. Campese, S. Checquolo, A. Balestri, A. Biondi, G. Cazzaniga, U. Lendahl, H. J. Fehling, A. C. Hayday, L. Frati, et al. (2002)
PNAS 99, 3788-3793
 |  Abstract »  |  Full Text »  |  PDF »

Blocking HES1 Expression Initiates GABAergic Differentiation and Induces the Expression of p21CIP1/WAF1 in Human Neural Stem Cells.

P. Kabos, A. Kabosova, and T. Neuman (2002)
J. Biol. Chem. 277, 8763-8766
 |  Abstract »  |  Full Text »  |  PDF »

c-Cbl Binding and Ubiquitin-dependent Lysosomal Degradation of Membrane-associated Notch1.

B. M. Jehn, I. Dittert, S. Beyer, K. von der Mark, and W. Bielke (2002)
J. Biol. Chem. 277, 8033-8040
 |  Abstract »  |  Full Text »  |  PDF »

Notch1 Perturbation of Hemopoiesis Involves Non-Cell- Autonomous Modifications.

S. Kawamata, C. Du, K. Li, and C. Lavau (2002)
J. Immunol. 168, 1738-1745
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon.

K. Yun, S. Fischman, J. Johnson, M. H. de Angelis, G. Weinmaster, and J. L. R. Rubenstein (2002)
Development 129, 5029-5040
 |  Abstract »  |  Full Text »  |  PDF »

Delta-Notch signaling induces hypochord development in zebrafish.

A. J. Latimer, X. Dong, Y. Markov, and B. Appel (2002)
Development 129, 2555-2563
 |  Abstract »  |  Full Text »  |  PDF »

Siah-1 binds and regulates the function of Numb.

L. Susini, B. J. Passer, N. Amzallag-Elbaz, T. Juven-Gershon, S. Prieur, N. Privat, M. Tuynder, M.-C. Gendron, A. Israel, R. Amson, et al. (2001)
PNAS 98, 15067-15072
 |  Abstract »  |  Full Text »  |  PDF »

Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression.

K. Kumano, S. Chiba, K. Shimizu, T. Yamagata, N. Hosoya, T. Saito, T. Takahashi, Y. Hamada, and H. Hirai (2001)
Blood 98, 3283-3289
 |  Abstract »  |  Full Text »  |  PDF »

p38 MAP Kinase Mediates Nitric Oxide-induced Apoptosis of Neural Progenitor Cells.

A. Cheng, S. L. Chan, O. Milhavet, S. Wang, and M. P. Mattson (2001)
J. Biol. Chem. 276, 43320-43327
 |  Abstract »  |  Full Text »  |  PDF »

Isolation of a Murine Homologue of the Drosophila neuralized Gene, a Gene Required for Axonemal Integrity in Spermatozoa and Terminal Maturation of the Mammary Gland.

B. Vollrath, J. Pudney, S. Asa, P. Leder, and K. Fitzgerald (2001)
Mol. Cell. Biol. 21, 7481-7494
 |  Abstract »  |  Full Text »  |  PDF »

Fetal Antigen 1 in Healthy Adults and Patients with Pituitary Disease: Relation to Physiological, Pathological, and Pharmacological GH Levels.

M. Andersen, C. H. Jensen, R. K. Stoving, J. B. Larsen, H. D. Schroder, B. Teisner, and C. Hagen (2001)
J. Clin. Endocrinol. Metab. 86, 5465-5470
 |  Abstract »  |  Full Text »  |  PDF »

A Functional Composite Cis-Element for NF{kappa}B and RBPJ{kappa} in the Rat Pregnancy-Specific Glycoprotein Gene.

C.-D. Wang, G.-D. Chang, Y.-K. Lee, and H. Chen (2001)
Biol Reprod 65, 1437-1443
 |  Abstract »  |  Full Text »  |  PDF »

Notch signalling and the initiation of neural development in the Drosophila eye.

A. Baonza and M. Freeman (2001)
Development 128, 3889-3898
 |  Abstract »  |  Full Text »  |  PDF »

Notch 1-deficient Common Lymphoid Precursors Adopt a B Cell Fate in the Thymus.

A. Wilson, H. R. MacDonald, and F. Radtke (2001)
J. Exp. Med. 194, 1003-1012
 |  Abstract »  |  Full Text »  |  PDF »

A Murine Homologue of the Drosophila brainiac Gene Shows Homology to Glycosyltransferases and Is Required for Preimplantation Development of the Mouse.

B. Vollrath, K. J. Fitzgerald, and P. Leder (2001)
Mol. Cell. Biol. 21, 5688-5697
 |  Abstract »  |  Full Text »  |  PDF »

Identifying intercellular signaling genes expressed in malignant plasma cells by using complementary DNA arrays.

J. De Vos, G. Couderc, K. Tarte, M. Jourdan, G. Requirand, M.-C. Delteil, J.-F. Rossi, N. Mechti, and B. Klein (2001)
Blood 98, 771-780
 |  Abstract »  |  Full Text »  |  PDF »

The EGF receptor and notch signaling pathways control the initiation of the morphogenetic furrow during Drosophila eye development.

J. P. Kumar and K. Moses (2001)
Development 128, 2689-2697
 |  Abstract »  |  Full Text »  |  PDF »

A Human Protein with Sequence Similarity to Drosophila Mastermind Coordinates the Nuclear Form of Notch and a CSL Protein To Build a Transcriptional Activator Complex on Target Promoters.

M. Kitagawa, T. Oyama, T. Kawashima, B. Yedvobnick, A. Kumar, K. Matsuno, and K. Harigaya (2001)
Mol. Cell. Biol. 21, 4337-4346
 |  Abstract »  |  Full Text »  |  PDF »

The Neural RNA-Binding Protein Musashi1 Translationally Regulates Mammalian numb Gene Expression by Interacting with Its mRNA.

T. Imai, A. Tokunaga, T. Yoshida, M. Hashimoto, K. Mikoshiba, G. Weinmaster, M. Nakafuku, and H. Okano (2001)
Mol. Cell. Biol. 21, 3888-3900
 |  Abstract »  |  Full Text »

Identification of a novel activation domain in the Notch-responsive transcription factor CSL.

Z. Tang and T. Kadesch (2001)
Nucleic Acids Res. 29, 2284-2291
 |  Abstract »  |  Full Text »  |  PDF »

A site in the complement receptor 2 (CR2/CD21) silencer is necessary for lineage specific transcriptional regulation.

K. W. Makar, D. Ulgiati, J. Hagman, and V. M. Holers (2001)
Int. Immunol. 13, 657-664
 |  Abstract »  |  Full Text »  |  PDF »

Epidermal Growth Factor-Like Repeats Mediate Lateral and Reciprocal Interactions of Ep-CAM Molecules in Homophilic Adhesions.

M. Balzar, I. H. Briaire-de Bruijn, H. A. M. Rees-Bakker, F. A. Prins, W. Helfrich, L. de Leij, G. Riethmüller, S. Alberti, S. O. Warnaar, G. J. Fleuren, et al. (2001)
Mol. Cell. Biol. 21, 2570-2580
 |  Abstract »  |  Full Text »

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