Science 24 March 1995: Vol. 267. no. 5205, pp. 1828 - 1831 DOI: 10.1126/science.7892608

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Articles

Blocking L-type calcium channels reduced the threshold of cAMP-induced steroidogenic acute regulatory gene expression in MA-10 mouse Leydig cells.

A. K Pandey, W. Li, X. Yin, D. M Stocco, P. Grammas, and X. Wang (2010)
J. Endocrinol. 204, 67-74
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Protein Kinase C Signaling in the Modulation of 3',5'-Cyclic Adenosine Monophosphate-Mediated Steroidogenesis in Mouse Gonadal Cells.

P. R. Manna, I. T. Huhtaniemi, and D. M. Stocco (2009)
Endocrinology 150, 3308-3317
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of the Thromboxane A2 Receptor in the Regulation of Steroidogenic Acute Regulatory Gene Expression in Murine Leydig Cells.

A. K. Pandey, X. Yin, R. B. Schiffer, J. C. Hutson, D. M. Stocco, P. Grammas, and X. Wang (2009)
Endocrinology 150, 3267-3273
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Regulation of the steroidogenic acute regulatory protein gene expression: present and future perspectives.

P. R. Manna, M. T. Dyson, and D. M. Stocco (2009)
Mol. Hum. Reprod. 15, 321-333
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Gonadal Function, First Cases of Pregnancy, and Child Delivery in a Woman with Lipoid Congenital Adrenal Hyperplasia.

K. Khoury, E. Barbar, Y. Ainmelk, A. Ouellet, and J.-G. LeHoux (2009)
J. Clin. Endocrinol. Metab. 94, 1333-1337
 |  Abstract »  |  Full Text »  |  PDF »

c-Fos Mediates Angiotensin II-Induced Aldosterone Production and Protein Synthesis in Bovine Adrenal Glomerulosa Cells.

J. M. Rincon Garriz, C. Suarez, and A. M. Capponi (2009)
Endocrinology 150, 1294-1302
 |  Abstract »  |  Full Text »  |  PDF »

Role of Dosage-Sensitive Sex Reversal, Adrenal Hypoplasia Congenita, Critical Region on the X Chromosome, Gene 1 in Protein Kinase A- and Protein Kinase C-Mediated Regulation of the Steroidogenic Acute Regulatory Protein Expression in Mouse Leydig Tumor Cells: Mechanism of Action.

P. R. Manna, M. T. Dyson, Y. Jo, and D. M. Stocco (2009)
Endocrinology 150, 187-199
 |  Abstract »  |  Full Text »  |  PDF »

The role of JUN in the regulation of PRKCC-mediated STAR expression and steroidogenesis in mouse Leydig cells.

P. R Manna and D. M Stocco (2008)
J. Mol. Endocrinol. 41, 329-341
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The Orphan Nuclear Receptor NUR77 Regulates Hormone-Induced StAR Transcription in Leydig Cells through Cooperation with Ca2+/Calmodulin-Dependent Protein Kinase I.

L. J. Martin, N. Boucher, C. Brousseau, and J. J. Tremblay (2008)
Mol. Endocrinol. 22, 2021-2037
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Orexins Stimulate Steroidogenic Acute Regulatory Protein Expression through Multiple Signaling Pathways in Human Adrenal H295R Cells.

M. Ramanjaneya, A. C. Conner, J. Chen, P. R. Stanfield, and H. S. Randeva (2008)
Endocrinology 149, 4106-4115
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation.

D. Rodriguez-Agudo, S. Ren, E. Wong, D. Marques, K. Redford, G. Gil, P. Hylemon, and W. M. Pandak (2008)
J. Lipid Res. 49, 1409-1419
 |  Abstract »  |  Full Text »  |  PDF »

New Enzymes Involved in the Mechanism of Action of Epidermal Growth Factor in a Clonal Strain of Leydig Tumor Cells.

R. Castilla, M. Gadaleta, A. F. Castillo, A. Duarte, I. Neuman, C. Paz, F. Cornejo Maciel, and E. J. Podesta (2008)
Endocrinology 149, 3743-3752
 |  Abstract »  |  Full Text »  |  PDF »

Progesterone stimulates the proliferation of female and male cholangiocytes via autocrine/paracrine mechanisms.

S. Glaser, S. DeMorrow, H. Francis, Y. Ueno, E. Gaudio, S. Vaculin, J. Venter, A. Franchitto, P. Onori, B. Vaculin, et al. (2008)
Am J Physiol Gastrointest Liver Physiol 295, G124-G136
 |  Abstract »  |  Full Text »  |  PDF »

Chrysin, a natural flavonoid enhances steroidogenesis and steroidogenic acute regulatory protein gene expression in mouse Leydig cells.

K. Jana, X. Yin, R. B Schiffer, J.-J. Chen, A. K Pandey, D. M Stocco, P. Grammas, and X. Wang (2008)
J. Endocrinol. 197, 315-323
 |  Abstract »  |  Full Text »  |  PDF »

Complex Role of the Mitochondrial Targeting Signal in the Function of Steroidogenic Acute Regulatory Protein Revealed by Bacterial Artificial Chromosome Transgenesis in Vivo.

G. Sasaki, T. Ishii, P. Jeyasuria, Y. Jo, A. Bahat, J. Orly, T. Hasegawa, and K. L. Parker (2008)
Mol. Endocrinol. 22, 951-964
 |  Abstract »  |  Full Text »  |  PDF »

A Lifetime of Aldosterone Excess: Long-Term Consequences of Altered Regulation of Aldosterone Production for Cardiovascular Function.

J. M. C. Connell, S. M. MacKenzie, E. M. Freel, R. Fraser, and E. Davies (2008)
Endocr. Rev. 29, 133-154
 |  Abstract »  |  Full Text »  |  PDF »

Severe Combined Adrenal and Gonadal Deficiency Caused by Novel Mutations in the Cholesterol Side Chain Cleavage Enzyme, P450scc.

C. J. Kim, L. Lin, N. Huang, C. A. Quigley, T. W. AvRuskin, J. C. Achermann, and W. L. Miller (2008)
J. Clin. Endocrinol. Metab. 93, 696-702
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Thromboxane A Synthase Activity Enhances Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in MA-10 Mouse Leydig Cells.

X. Wang, X. Yin, R. B. Schiffer, S. R. King, D. M. Stocco, and P. Grammas (2008)
Endocrinology 149, 851-857
 |  Abstract »  |  Full Text »  |  PDF »

Activin A and Equine Chorionic Gonadotropin Recover Reproductive Dysfunction Induced by Neonatal Exposure to an Estrogenic Endocrine Disruptor in Adult Male Mice.

K. Warita, K. Okamoto, K.-i. Mutoh, Y. Hasegawa, Z.-P. Yue, T. Yokoyama, Y. Matsumoto, T. Miki, Y. Takeuchi, H. Kitagawa, et al. (2008)
Biol Reprod 78, 59-67
 |  Abstract »  |  Full Text »  |  PDF »

Prostaglandin F2{alpha} Suppresses Rat Steroidogenic Acute Regulatory Protein Expression via Induction of Yin Yang 1 Protein and Recruitment of Histone Deacetylase 1 Protein.

Q. Liu, K. A. Merkler, X. Zhang, and M. P. McLean (2007)
Endocrinology 148, 5209-5219
 |  Abstract »  |  Full Text »  |  PDF »

Role of a Founder c.201_202delCT Mutation and New Phenotypic Features of Congenital Lipoid Adrenal Hyperplasia in Palestinians.

M. Abdulhadi-Atwan, A. Jean, W. K. Chung, K. Meir, Z. Ben Neriah, G. Stratigopoulos, S. E. Oberfield, I. Fennoy, H. J. Hirsch, A. Bhangoo, et al. (2007)
J. Clin. Endocrinol. Metab. 92, 4000-4008
 |  Abstract »  |  Full Text »  |  PDF »

Turnover of Mitochondrial Steroidogenic Acute Regulatory (StAR) Protein by Lon Protease: The Unexpected Effect of Proteasome Inhibitors.

Z. Granot, O. Kobiler, N. Melamed-Book, S. Eimerl, A. Bahat, B. Lu, S. Braun, M. R. Maurizi, C. K. Suzuki, A. B. Oppenheim, et al. (2007)
Mol. Endocrinol. 21, 2164-2177
 |  Abstract »  |  Full Text »  |  PDF »

B-Type Natriuretic Peptide Inhibited Angiotensin II-Stimulated Cholesterol Biosynthesis, Cholesterol Transfer, and Steroidogenesis in Primary Human Adrenocortical Cells.

F. Liang, A. M. Kapoun, A. Lam, D. L. Damm, D. Quan, M. O'Connell, and A. A. Protter (2007)
Endocrinology 148, 3722-3729
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Folding, activity and import of steroidogenic acute regulatory protein into mitochondria changed by nicotine exposure.

M. Bose, D. Debnath, Y. Chen, and H. S Bose (2007)
J. Mol. Endocrinol. 39, 67-79
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Cholesterol Binding Does Not Predict Activity of the Steroidogenic Acute Regulatory Protein, StAR.

B. Y. Baker, R. F. Epand, R. M. Epand, and W. L. Miller (2007)
J. Biol. Chem. 282, 10223-10232
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Leydig cell steroidogenesis by extracellular signal-regulated kinase 1/2: role of protein kinase A and protein kinase C signaling.

P. R Manna, Y. Jo, and D. M Stocco (2007)
J. Endocrinol. 193, 53-63
 |  Abstract »  |  Full Text »  |  PDF »

Effects of genistein, resveratrol, and quercetin on steroidogenesis and proliferation of MA-10 mouse Leydig tumor cells.

Y.-C. Chen, M. L Nagpal, D. M Stocco, and T. Lin (2007)
J. Endocrinol. 192, 527-537
 |  Abstract »  |  Full Text »  |  PDF »

StAR Search--What We Know about How the Steroidogenic Acute Regulatory Protein Mediates Mitochondrial Cholesterol Import.

W. L. Miller (2007)
Mol. Endocrinol. 21, 589-601
 |  Abstract »  |  Full Text »  |  PDF »

Modeling the structure of the StART domains of MLN64 and StAR proteins in complex with cholesterol.

M. Murcia, J. D. Faraldo-Gomez, F. R. Maxfield, and B. Roux (2006)
J. Lipid Res. 47, 2614-2630
 |  Abstract »  |  Full Text »  |  PDF »

Nonclassic Congenital Lipoid Adrenal Hyperplasia: A New Disorder of the Steroidogenic Acute Regulatory Protein with Very Late Presentation and Normal Male Genitalia.

B. Y. Baker, L. Lin, C. J. Kim, J. Raza, C. P. Smith, W. L. Miller, and J. C. Achermann (2006)
J. Clin. Endocrinol. Metab. 91, 4781-4785
 |  Abstract »  |  Full Text »  |  PDF »

CREM confers cAMP responsiveness in human steroidogenic acute regulatory protein expression in NCI-H295R cells rather than SF-1/Ad4BP..

T. Sugawara, N. Sakuragi, and H. Minakami (2006)
J. Endocrinol. 191, 327-337
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms for cellular cholesterol transport: defects and human disease..

E. Ikonen (2006)
Physiol Rev 86, 1237-1261
 |  Abstract »  |  Full Text »  |  PDF »

The involvement of epoxygenase metabolites of arachidonic acid in cAMP-stimulated steroidogenesis and steroidogenic acute regulatory protein gene expression..

X. Wang, C.-L. Shen, M. T Dyson, X. Yin, R. B Schiffer, P. Grammas, and D. M Stocco (2006)
J. Endocrinol. 190, 871-878
 |  Abstract »  |  Full Text »  |  PDF »

A novel mutation in the steroidogenic acute regulatory protein gene promoter leading to reduced promoter activity..

A. J Casal, V. J P Sinclair, A. M Capponi, J. Nicod, U. Huynh-Do, and P. Ferrari (2006)
J. Mol. Endocrinol. 37, 71-80
 |  Abstract »  |  Full Text »  |  PDF »

cAMP-independent signaling regulates steroidogenesis in mouse Leydig cells in the absence of StAR phosphorylation..

P. R Manna, S. P Chandrala, Y. Jo, and D. M Stocco (2006)
J. Mol. Endocrinol. 37, 81-95
 |  Abstract »  |  Full Text »  |  PDF »

Localization of StarD5 cholesterol binding protein.

D. Rodriguez-Agudo, S. Ren, P. B. Hylemon, R. Montanez, K. Redford, R. Natarajan, M. A. Medina, G. Gil, and W. M. Pandak (2006)
J. Lipid Res. 47, 1168-1175
 |  Abstract »  |  Full Text »  |  PDF »

Somatotropic and Gonadotropic Axes Linkages in Infancy, Childhood, and the Puberty-Adult Transition.

J. D. Veldhuis, J. N. Roemmich, E. J. Richmond, and C. Y. Bowers (2006)
Endocr. Rev. 27, 101-140
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Mechanisms of Insulin-like Growth Factor-I Mediated Regulation of the Steroidogenic Acute Regulatory Protein in Mouse Leydig Cells.

P. R. Manna, S. P. Chandrala, S. R. King, Y. Jo, R. Counis, I. T. Huhtaniemi, and D. M. Stocco (2006)
Mol. Endocrinol. 20, 362-378
 |  Abstract »  |  Full Text »  |  PDF »

Association of the mSin3A-Histone Deacetylase 1/2 Corepressor Complex with the Mouse Steroidogenic Acute Regulatory Protein Gene.

B. F. Clem and B. J. Clark (2006)
Mol. Endocrinol. 20, 100-113
 |  Abstract »  |  Full Text »  |  PDF »

Activation of a Neural Brain-Testicular Pathway Rapidly Lowers Leydig Cell Levels of the Steroidogenic Acute Regulatory Protein and the Peripheral-Type Benzodiazepine Receptor while Increasing Levels of Neuronal Nitric Oxide Synthase.

M. Herman and C. Rivier (2006)
Endocrinology 147, 624-633
 |  Abstract »  |  Full Text »  |  PDF »

A pH-dependent Molten Globule Transition Is Required for Activity of the Steroidogenic Acute Regulatory Protein, StAR.

B. Y. Baker, D. C. Yaworsky, and W. L. Miller (2005)
J. Biol. Chem. 280, 41753-41760
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Signaling Pathways Regulating Steroidogenesis and Steroidogenic Acute Regulatory Protein Expression: More Complicated than We Thought.

D. M. Stocco, X. Wang, Y. Jo, and P. R. Manna (2005)
Mol. Endocrinol. 19, 2647-2659
 |  Abstract »  |  Full Text »  |  PDF »

Phenotypic Features Associated with Mutations in Steroidogenic Acute Regulatory Protein.

A. Bhangoo, W.-X. Gu, S. Pavlakis, H. Anhalt, L. Heier, S. Ten, and J. L. Jameson (2005)
J. Clin. Endocrinol. Metab. 90, 6303-6309
 |  Abstract »  |  Full Text »  |  PDF »

Cyclooxygenase-2 Regulation of the Age-Related Decline in Testosterone Biosynthesis.

X. Wang, C.-L. Shen, M. T. Dyson, S. Eimerl, J. Orly, J. C. Hutson, and D. M. Stocco (2005)
Endocrinology 146, 4202-4208
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Mutation L260P of the Steroidogenic Acute Regulatory Protein Gene in Three Unrelated Patients of Swiss Ancestry with Congenital Lipoid Adrenal Hyperplasia.

C. E. Fluck, A. Maret, D. Mallet, S. Portrat-Doyen, J. C. Achermann, B. Leheup, G. E. Theintz, P. E. Mullis, and Y. Morel (2005)
J. Clin. Endocrinol. Metab. 90, 5304-5308
 |  Abstract »  |  Full Text »  |  PDF »

Human StarD5, a cytosolic StAR-related lipid binding protein.

D. Rodriguez-Agudo, S. Ren, P. B. Hylemon, K. Redford, R. Natarajan, A. Del Castillo, G. Gil, and W. M. Pandak (2005)
J. Lipid Res. 46, 1615-1623
 |  Abstract »  |  Full Text »  |  PDF »

The new biology of aldosterone.

J. M C Connell and E. Davies (2005)
J. Endocrinol. 186, 1-20
 |  Abstract »  |  Full Text »  |  PDF »

Give lipids a START: the StAR-related lipid transfer (START) domain in mammals.

F. Alpy and C. Tomasetto (2005)
J. Cell Sci. 118, 2791-2801
 |  Abstract »  |  Full Text »  |  PDF »

Peripheral-Type Benzodiazepine Receptor-Mediated Action of Steroidogenic Acute Regulatory Protein on Cholesterol Entry into Leydig Cell Mitochondria.

T. Hauet, Z.-X. Yao, H. S. Bose, C. T. Wall, Z. Han, W. Li, D. B. Hales, W. L. Miller, M. Culty, and V. Papadopoulos (2005)
Mol. Endocrinol. 19, 540-554
 |  Abstract »  |  Full Text »  |  PDF »

A Genetic Isolate of Congenital Lipoid Adrenal Hyperplasia with Atypical Clinical Findings.

X. Chen, B. Y. Baker, M. A. Abduljabbar, and W. L. Miller (2005)
J. Clin. Endocrinol. Metab. 90, 835-840
 |  Abstract »  |  Full Text »  |  PDF »

pH-dependent Interactions of the Carboxyl-terminal Helix of Steroidogenic Acute Regulatory Protein with Synthetic Membranes.

D. C. Yaworsky, B. Y. Baker, H. S. Bose, K. B. Best, L. B. Jensen, J. D. Bell, M. A. Baldwin, and W. L. Miller (2005)
J. Biol. Chem. 280, 2045-2054
 |  Abstract »  |  Full Text »  |  PDF »

Homozygous Disruption of P450 Side-Chain Cleavage (CYP11A1) Is Associated with Prematurity, Complete 46,XY Sex Reversal, and Severe Adrenal Failure.

O. Hiort, P.-M. Holterhus, R. Werner, C. Marschke, U. Hoppe, C.-J. Partsch, F. G. Riepe, J. C. Achermann, and D. Struve (2005)
J. Clin. Endocrinol. Metab. 90, 538-541
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Steroidogenesis and Steroidogenic Acute Regulatory Protein in R2C Cells by DAX-1 (Dosage-Sensitive Sex Reversal, Adrenal Hypoplasia Congenita, Critical Region on the X Chromosome, Gene-1).

Y. Jo and D. M. Stocco (2004)
Endocrinology 145, 5629-5637
 |  Abstract »  |  Full Text »  |  PDF »

The Steroidogenic Acute Regulatory Protein Is Expressed in Steroidogenic Cells of the Day-Old Brain.

S. R. King, S. D. Ginsberg, T. Ishii, R. G. Smith, K. L. Parker, and D. J. Lamb (2004)
Endocrinology 145, 4775-4780
 |  Abstract »  |  Full Text »  |  PDF »

Concerted Regulation of the Porcine Steroidogenic Acute Regulatory Protein Gene Promoter Activity by Follicle-Stimulating Hormone and Insulin-Like Growth Factor I in Granulosa Cells Involves GATA-4 and CCAAT/Enhancer Binding Protein {beta}.

H. A. LaVoie, D. Singh, and Y. Y. Hui (2004)
Endocrinology 145, 3122-3134
 |  Abstract »  |  Full Text »  |  PDF »

Forkhead L2 Is Expressed in the Ovary and Represses the Promoter Activity of the Steroidogenic Acute Regulatory Gene.

M. D. Pisarska, J. Bae, C. Klein, and A. J. W. Hsueh (2004)
Endocrinology 145, 3424-3433
 |  Abstract »  |  Full Text »  |  PDF »

Aberrant Cholesterol Transport and Impaired Steroidogenesis in Leydig Cells Lacking Estrogen Sulfotransferase.

M. H. Tong, L. K. Christenson, and W.-C. Song (2004)
Endocrinology 145, 2487-2497
 |  Abstract »  |  Full Text »  |  PDF »

Targeted Mutation of the MLN64 START Domain Causes Only Modest Alterations in Cellular Sterol Metabolism.

T. Kishida, I. Kostetskii, Z. Zhang, F. Martinez, P. Liu, S. U. Walkley, N. K. Dwyer, E. J. Blanchette-Mackie, G. L. Radice, and J. F. Strauss III (2004)
J. Biol. Chem. 279, 19276-19285
 |  Abstract »  |  Full Text »  |  PDF »

Control of Aldosterone Secretion: A Model for Convergence in Cellular Signaling Pathways.

A. SPAT and L. HUNYADY (2004)
Physiol Rev 84, 489-539
 |  Abstract »  |  Full Text »  |  PDF »

Molten Globule Structure and Steroidogenic Activity of N-218 MLN64 in Human Placental Mitochondria.

R. C. Tuckey, H. S. Bose, I. Czerwionka, and W. L. Miller (2004)
Endocrinology 145, 1700-1707
 |  Abstract »  |  Full Text »  |  PDF »

Cholecystokinin (CCK) Stimulates Aldosterone Secretion from Human Adrenocortical Cells via CCK2 Receptors Coupled to the Adenylate Cyclase/Protein Kinase A Signaling Cascade.

G. Mazzocchi, L. K. Malendowicz, F. Aragona, R. Spinazzi, and G. G. Nussdorfer (2004)
J. Clin. Endocrinol. Metab. 89, 1277-1284
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Characterization of Postnatal Development of Testicular Steroidogenesis in Luteinizing Hormone Receptor Knockout Mice.

F.-p. Zhang, T. Pakarainen, F. Zhu, M. Poutanen, and I. Huhtaniemi (2004)
Endocrinology 145, 1453-1463
 |  Abstract »  |  Full Text »  |  PDF »

Congenital Lipoid Adrenal Hyperplasia Caused by a Novel Splicing Mutation in the Gene for the Steroidogenic Acute Regulatory Protein.

A. A. Gonzalez, M. L. Reyes, C. A. Carvajal, J. A. Tobar, L. M. Mosso, P. Baquedano, A. Solar, A. Venegas, and C. E. Fardella (2004)
J. Clin. Endocrinol. Metab. 89, 946-951
 |  Abstract »  |  Full Text »  |  PDF »

Steroid 17{alpha}-Hydroxylase Deficiency--Not Rare Everywhere.

W. L. Miller (2004)
J. Clin. Endocrinol. Metab. 89, 40-42
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The Effects of Low-level Pb on Steroidogenic Acute Regulatory Protein (StAR) in the Prepubertal Rat Ovary.

V. Srivastava, R. K. Dearth, J. K. Hiney, L. M. Ramirez, G. R. Bratton, and W. Les Dees (2004)
Toxicol. Sci. 77, 35-40
 |  Abstract »  |  Full Text »  |  PDF »

Janus Kinase 2 and Calcium Are Required for Angiotensin II-dependent Activation of Steroidogenic Acute Regulatory Protein Transcription in H295R Human Adrenocortical Cells.

J. Li, R. E. Feltzer, K. L. Dawson, E. A. Hudson, and B. J. Clark (2003)
J. Biol. Chem. 278, 52355-52362
 |  Abstract »  |  Full Text »  |  PDF »

Proteolysis of Normal and Mutated Steroidogenic Acute Regulatory Proteins in the Mitochondria: the Fate of Unwanted Proteins.

Z. Granot, R. Geiss-Friedlander, N. Melamed-Book, S. Eimerl, R. Timberg, A. M. Weiss, K. H. Hales, D. B. Hales, D. M. Stocco, and J. Orly (2003)
Mol. Endocrinol. 17, 2461-2476
 |  Abstract »  |  Full Text »  |  PDF »

Intratesticular Delivery of Tumor Necrosis Factor-{alpha} and Ceramide Directly Abrogates Steroidogenic Acute Regulatory Protein Expression and Leydig Cell Steroidogenesis in Adult Rats.

V. Morales, P. Santana, R. Diaz, C. Tabraue, G. Gallardo, F. L. Blanco, I. Hernandez, L. F. Fanjul, and C. M. Ruiz de Galarreta (2003)
Endocrinology 144, 4763-4772
 |  Abstract »  |  Full Text »  |  PDF »

Steroidogenic Acute Regulatory Protein-binding Protein Cloned by a Yeast Two-hybrid System.

T. Sugawara, H. Shimizu, N. Hoshi, A. Nakajima, and S. Fujimoto (2003)
J. Biol. Chem. 278, 42487-42494
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Cyclooxygenase-2 Activity Enhances Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in MA-10 Mouse Leydig Cells.

X. Wang, M. T. Dyson, Y. Jo, and D. M. Stocco (2003)
Endocrinology 144, 3368-3375
 |  Abstract »  |  Full Text »  |  PDF »

Steroidogenic Acute Regulatory Protein in Ovarian Follicles of Gonadotropin-Stimulated Rats Is Regulated by a Gonadotropin-Releasing Hormone Agonist.

G. Irusta, F. Parborell, M. Peluffo, P. R. Manna, S. I. Gonzalez-Calvar, R. Calandra, D. M. Stocco, and M. Tesone (2003)
Biol Reprod 68, 1577-1583
 |  Abstract »  |  Full Text »  |  PDF »

Accelerated germ cell apoptosis in sex chromosome aneuploid fetal human gonads.

D.N. Modi, S. Sane, and D. Bhartiya (2003)
Mol. Hum. Reprod. 9, 219-225
 |  Abstract »  |  Full Text »  |  PDF »

Stimulatory Effect of Progesterone on the Expression of Steroidogenic Acute Regulatory Protein in MA-10 Leydig Cells.

H. Schwarzenbach, P. R. Manna, D. M. Stocco, G. Chakrabarti, and A. K. Mukhopadhyay (2003)
Biol Reprod 68, 1054-1063
 |  Abstract »  |  Full Text »  |  PDF »

Differential Regulation of Steroid Hormone Biosynthesis in R2C and MA-10 Leydig Tumor Cells: Role of SR-B1-Mediated Selective Cholesteryl Ester Transport.

R. M. Rao, Y. Jo, S. Leers-Sucheta, H. S. Bose, W. L. Miller, S. Azhar, and D. M. Stocco (2003)
Biol Reprod 68, 114-121
 |  Abstract »  |  Full Text »  |  PDF »

An Essential Component in Steroid Synthesis, the Steroidogenic Acute Regulatory Protein, Is Expressed in Discrete Regions of the Brain.

S. R. King, P. R. Manna, T. Ishii, P. J. Syapin, S. D. Ginsberg, K. Wilson, L. P. Walsh, K. L. Parker, D. M. Stocco, R. G. Smith, et al. (2002)
J. Neurosci. 22, 10613-10620
 |  Abstract »  |  Full Text »  |  PDF »

Transfer of Cholesterol between Phospholipid Vesicles Mediated by the Steroidogenic Acute Regulatory Protein (StAR).

R. C. Tuckey, M. J. Headlam, H. S. Bose, and W. L. Miller (2002)
J. Biol. Chem. 277, 47123-47128
 |  Abstract »  |  Full Text »  |  PDF »

Smad4 Overexpression Causes Germ Cell Ablation and Leydig Cell Hyperplasia in Transgenic Mice.

A. Narula, S. Kilen, E. Ma, J. Kroeger, E. Goldberg, and T. K. Woodruff (2002)
Am. J. Pathol. 161, 1723-1734
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Epidermal Growth Factor Signaling: Regulation of Steroid Biosynthesis and the Steroidogenic Acute Regulatory Protein in Mouse Leydig Tumor Cells.

P. R. Manna, I. T. Huhtaniemi, X.-J. Wang, D. W. Eubank, and D. M. Stocco (2002)
Biol Reprod 67, 1393-1404
 |  Abstract »  |  Full Text »  |  PDF »

The Transcriptional Regulating Protein of 132 kDa (TReP-132) Enhances P450scc Gene Transcription through Interaction with Steroidogenic Factor-1 in Human Adrenal Cells.

F. Gizard, B. Lavallee, F. DeWitte, E. Teissier, B. Staels, and D. W. Hum (2002)
J. Biol. Chem. 277, 39144-39155
 |  Abstract »  |  Full Text »  |  PDF »

The Roles of Circulating High-Density Lipoproteins and Trophic Hormones in the Phenotype of Knockout Mice Lacking the Steroidogenic Acute Regulatory Protein.

T. Ishii, T. Hasegawa, C.-I Pai, N. Yvgi-Ohana, R. Timberg, L. Zhao, G. Majdic, B.-c. Chung, J. Orly, and K. L. Parker (2002)
Mol. Endocrinol. 16, 2297-2309
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Steroidogenic Genes by Insulin-Like Growth Factor-1 and Follicle-Stimulating Hormone: Differential Responses of Cytochrome P450 Side-Chain Cleavage, Steroidogenic Acute Regulatory Protein, and 3{beta}-Hydroxysteroid Dehydrogenase/Isomerase in Rat Granulosa Cells.

S. Eimerl and J. Orly (2002)
Biol Reprod 67, 900-910
 |  Abstract »  |  Full Text »  |  PDF »

Compound Heterozygous Mutations in the Cholesterol Side-Chain Cleavage Enzyme Gene (CYP11A) Cause Congenital Adrenal Insufficiency in Humans.

N. Katsumata, M. Ohtake, T. Hojo, E. Ogawa, T. Hara, N. Sato, and T. Tanaka (2002)
J. Clin. Endocrinol. Metab. 87, 3808-3813
 |  Abstract »  |  Full Text »  |  PDF »

Monogenic Disorders of Puberty.

S. N. Kalantaridou and G. P. Chrousos (2002)
J. Clin. Endocrinol. Metab. 87, 2481-2494
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Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain.

M. J. Romanowski, R. E. Soccio, J. L. Breslow, and S. K. Burley (2002)
PNAS 99, 6949-6954
 |  Abstract »  |  Full Text »  |  PDF »

Oxytocin Receptor Regulation and Action in a Human Granulosa-Lutein Cell Line.

J. A. Copland, M. G. Zlatnik, K. L. Ives, and M. S. Soloff (2002)
Biol Reprod 66, 1230-1236
 |  Abstract »  |  Full Text »

Autoimmune Adrenocortical Failure in Norway Autoantibodies and Human Leukocyte Antigen Class II Associations Related to Clinical Features.

A. G. Myhre, D. E. Undlien, K. Lovas, S. Uhlving, B. G. Nedrebo, K. J. Fougner, T. Trovik, J. I. Sorheim, and E. S. Husebye (2002)
J. Clin. Endocrinol. Metab. 87, 618-623
 |  Abstract »  |  Full Text »  |  PDF »

Interaction Between Dax-1 and Steroidogenic Factor-1 in Vivo: Increased Adrenal Responsiveness to ACTH in the Absence of Dax-1.

P. S. Babu, D. L. Bavers, F. Beuschlein, S. Shah, B. Jeffs, J. L. Jameson, and G. D. Hammer (2002)
Endocrinology 143, 665-673
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Steroidogenesis and the Steroidogenic Acute Regulatory Protein by a Member of the cAMP Response-Element Binding Protein Family.

P. R. Manna, M. T. Dyson, D. W. Eubank, B. J. Clark, E. Lalli, P. Sassone-Corsi, A. J. Zeleznik, and D. M. Stocco (2002)
Mol. Endocrinol. 16, 184-199
 |  Abstract »  |  Full Text »  |  PDF »

Mitochondrial Processing of Newly Synthesized Steroidogenic Acute Regulatory Protein (StAR), but Not Total StAR, Mediates Cholesterol Transfer to Cytochrome P450 Side Chain Cleavage Enzyme in Adrenal Cells.

I. P. Artemenko, D. Zhao, D. B. Hales, K. H. Hales, and C. R. Jefcoate (2001)
J. Biol. Chem. 276, 46583-46596
 |  Abstract »  |  Full Text »  |  PDF »

Recent Advances in Membrane Microdomains: Rafts, Caveolae, and Intracellular Cholesterol Trafficking.

F. Schroeder, A. M. Gallegos, B. P. Atshaves, S. M. Storey, A. L. McIntosh, A. D. Petrescu, H. Huang, O. Starodub, H. Chao, H. Yang, et al. (2001)
Experimental Biology and Medicine 226, 873-890
 |  Abstract »  |  Full Text »  |  PDF »

The OSBP-related protein family in humans.

M. Lehto, S. Laitinen, G. Chinetti, M. Johansson, C. Ehnholm, B. Staels, E. Ikonen, and V. M. Olkkonen (2001)
J. Lipid Res. 42, 1203-1213
 |  Abstract »  |  Full Text »  |  PDF »

Heterozygous Mutation in the Cholesterol Side Chain Cleavage Enzyme (P450scc) Gene in a Patient with 46,XY Sex Reversal and Adrenal Insufficiency.

T. Tajima, K. Fujieda, N. Kouda, J. Nakae, and W. L. Miller (2001)
J. Clin. Endocrinol. Metab. 86, 3820-3825
 |  Abstract »  |  Full Text »  |  PDF »

Tracking the Role of a StAR in the Sky of the New Millennium.

D. M. Stocco (2001)
Mol. Endocrinol. 15, 1245-1254
 |  Abstract »  |  Full Text »  |  PDF »

Salt-Inducible Kinase Is Involved in the ACTH/cAMP-Dependent Protein Kinase Signaling in Y1 Mouse Adrenocortical Tumor Cells.

X.-z. Lin, H. Takemori, Y. Katoh, J. Doi, N. Horike, A. Makino, Y. Nonaka, and M. Okamoto (2001)
Mol. Endocrinol. 15, 1264-1276
 |  Abstract »  |  Full Text »  |  PDF »

Decreased Expression of Steroidogenic Acute Regulatory Protein: A Novel Mechanism Participating in the Leptin-Induced Inhibition of Glucocorticoid Biosynthesis.

N. Cherradi, A. M. Capponi, R. C. Gaillard, and F. P. Pralong (2001)
Endocrinology 142, 3302-3308
 |  Abstract »  |  Full Text »  |  PDF »

RIP 140 Modulates Transcription of the Steroidogenic Acute Regulatory Protein Gene through Interactions with Both SF-1 and DAX-1.

T. Sugawara, S. Abe, N. Sakuragi, Y. Fujimoto, E. Nomura, K. Fujieda, M. Saito, and S. Fujimoto (2001)
Endocrinology 142, 3570-3577
 |  Abstract »  |  Full Text »  |  PDF »

Lipoid Congenital Adrenal Hyperplasia (CAH): Patient Report and a Mini-Review.

E. J. Richmond, C. J. Flickinger, J. A. McDonald, M. A. Lovell, and A. D. Rogol (2001)
Clinical Pediatrics 40, 403-407
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Leukemia Inhibitory Factor Antagonizes Gonadotropin Induced-Testosterone Synthesis in Cultured Porcine Leydig Cells: Sites of Action.

C. Mauduit, I. Goddard, V. Besset, E. Tabone, C. Rey, F. Gasnier, F. Dacheux, and M. Benahmed (2001)
Endocrinology 142, 2509-2520
 |  Abstract »  |  Full Text »  |  PDF »

Creation and Activity of COS-1 Cells Stably Expressing the F2 Fusion of the Human Cholesterol Side-Chain Cleavage Enzyme System.

M.-C. Huang and W. L. Miller (2001)
Endocrinology 142, 2569-2576
 |  Abstract »  |  Full Text »  |  PDF »

Ectopic and Abnormal Hormone Receptors in Adrenal Cushing's Syndrome.

A. Lacroix, N. N'Diaye, J. Tremblay, and P. Hamet (2001)
Endocr. Rev. 22, 75-110
 |  Abstract »  |  Full Text »

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