Science 24 March 1995: Vol. 267. no. 5205, pp. 1782 - 1788 DOI: 10.1126/science.7892601

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Articles

Neurotrophin NT3 promotes ovarian primordial to primary follicle transition.

E. Nilsson, G. Dole, and M. K Skinner (2009)
Reproduction 138, 697-707
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Involvement of JAK-STAT signaling/function after cyclophosphamide-induced bladder inflammation in female rats.

B. P. Cheppudira, B. M. Girard, S. E. Malley, A. Dattilio, K. C. Schutz, V. May, and M. A. Vizzard (2009)
Am J Physiol Renal Physiol 297, F1038-F1044
 |  Abstract »  |  Full Text »  |  PDF »

RiceArrayNet: A Database for Correlating Gene Expression from Transcriptome Profiling, and Its Application to the Analysis of Coexpressed Genes in Rice.

T.-H. Lee, Y.-K. Kim, T. T. M. Pham, S. I. Song, J.-K. Kim, K. Y. Kang, G. An, K.-H. Jung, D. W. Galbraith, M. Kim, et al. (2009)
Plant Physiology 151, 16-33
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Bile Acid-induced Epidermal Growth Factor Receptor Activation in Quiescent Rat Hepatic Stellate Cells Can Trigger Both Proliferation and Apoptosis.

A. Sommerfeld, R. Reinehr, and D. Haussinger (2009)
J. Biol. Chem. 284, 22173-22183
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ERBB1 and ERBB2 Have Distinct Functions in Tumor Cell Invasion and Intravasation.

D. Kedrin, J. Wyckoff, P. J. Boimel, S. J. Coniglio, N. E. Hynes, C. L. Arteaga, and J. E. Segall (2009)
Clin. Cancer Res. 15, 3733-3739
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Decorin is a novel antagonistic ligand of the Met receptor.

S. Goldoni, A. Humphries, A. Nystrom, S. Sattar, R. T. Owens, D. J. McQuillan, K. Ireton, and R. V. Iozzo (2009)
J. Cell Biol. 185, 743-754
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Protein Kinase D Mediates Mitogenic Signaling by Gq-coupled Receptors through Protein Kinase C-independent Regulation of Activation Loop Ser744 and Ser748 Phosphorylation.

J. Sinnett-Smith, R. Jacamo, R. Kui, Y. M. Wang, S. H. Young, O. Rey, R. T. Waldron, and E. Rozengurt (2009)
J. Biol. Chem. 284, 13434-13445
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Epidermal growth factor receptor is involved in enterocyte anoikis through the dismantling of E-cadherin-mediated junctions.

V.-H. Lugo-Martinez, C. S. Petit, S. Fouquet, J. Le Beyec, J. Chambaz, M. Pincon-Raymond, P. Cardot, and S. Thenet (2009)
Am J Physiol Gastrointest Liver Physiol 296, G235-G244
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A Novel Small Molecule Regulator of Guanine Nucleotide Exchange Activity of the ADP-ribosylation Factor and Golgi Membrane Trafficking.

H. Pan, J. Yu, L. Zhang, A. Carpenter, H. Zhu, L. Li, D. Ma, and J. Yuan (2008)
J. Biol. Chem. 283, 31087-31096
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Protein Tyrosine Kinases and Protein Tyrosine Phosphatases Are Involved in Abscisic Acid-Dependent Processes in Arabidopsis Seeds and Suspension Cells.

T. Ghelis, G. Bolbach, G. Clodic, Y. Habricot, E. Miginiac, B. Sotta, and E. Jeannette (2008)
Plant Physiology 148, 1668-1680
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An Antimetastatic Role for Decorin in Breast Cancer.

S. Goldoni, D. G. Seidler, J. Heath, M. Fassan, R. Baffa, M. L. Thakur, R. T. Owens, D. J. McQuillan, and R. V. Iozzo (2008)
Am. J. Pathol. 173, 844-855
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Signal Transducer and Activator of Transcription 5b, c-Src, and Epidermal Growth Factor Receptor Signaling Play Integral Roles in Estrogen-Stimulated Proliferation of Estrogen Receptor-Positive Breast Cancer Cells.

E. M. Fox, T. M. Bernaciak, J. Wen, A. M. Weaver, M. A. Shupnik, and C. M. Silva (2008)
Mol. Endocrinol. 22, 1781-1796
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Cultured rat hepatocytes upregulate Akt and ERK in an ErbB-2-dependent manner.

L. A. Scheving, M. C. Stevenson, X. Zhang, and W. E. Russell (2008)
Am J Physiol Gastrointest Liver Physiol 295, G322-G331
 |  Abstract »  |  Full Text »  |  PDF »

Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation.

E. H. Budi, L. B. Patterson, and D. M. Parichy (2008)
Development 135, 2603-2614
 |  Abstract »  |  Full Text »  |  PDF »

Neuregulin-mediated ErbB3 signaling is required for formation of zebrafish dorsal root ganglion neurons.

Y. Honjo, J. Kniss, and J. S. Eisen (2008)
Development 135, 2615-2625
 |  Abstract »  |  Full Text »  |  PDF »

Synergistic Inhibition of ErbB Signaling by Combined Treatment with Seliciclib and ErbB-Targeting Agents.

I. N. Fleming, M. Hogben, S. Frame, S. J. McClue, and S. R. Green (2008)
Clin. Cancer Res. 14, 4326-4335
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Epidermal Growth Factor Plays a Crucial Role in Mitogenic Regulation of Human Brain Tumor Stem Cells.

A. Soeda, A. Inagaki, N. Oka, Y. Ikegame, H. Aoki, S.-i. Yoshimura, S. Nakashima, T. Kunisada, and T. Iwama (2008)
J. Biol. Chem. 283, 10958-10966
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Evidence That Sprouty 2 Is Necessary for Sarcoma Formation by H-Ras Oncogene-transformed Human Fibroblasts.

P. Lito, B. D. Mets, S. Kleff, S. O'Reilly, V. M. Maher, and J. J. McCormick (2008)
J. Biol. Chem. 283, 2002-2009
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Mechanism of Angiotensin II-induced Superoxide Production in Cells Reconstituted with Angiotensin Type 1 Receptor and the Components of NADPH Oxidase.

H. Choi, T. L. Leto, L. Hunyady, K. J. Catt, Y. S. Bae, and S. G. Rhee (2008)
J. Biol. Chem. 283, 255-267
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Blockage of JAK/STAT signalling attenuates renal ischaemia-reperfusion injury in rats.

N. Yang, M. Luo, R. Li, Y. Huang, R. Zhang, Q. Wu, F. Wang, Y. Li, and X. Yu (2008)
Nephrol. Dial. Transplant. 23, 91-100
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Tyrphostin A8 stimulates a novel trafficking pathway of apically endocytosed transferrin through Rab11-enriched compartments in Caco-2 cells.

F. Norouziyan, W.-C. Shen, and S. F. Hamm-Alvarez (2008)
Am J Physiol Cell Physiol 294, C7-C21
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Epidermal Growth Factor Receptor Phosphorylates Protein Kinase C {delta} at Tyr332 to form a Trimeric Complex with p66Shc in the H2O2-stimulated Cells.

M. Morita, H. Matsuzaki, T. Yamamoto, Y. Fukami, and U. Kikkawa (2008)
J. Biochem. 143, 31-38
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Liver injury after an aggressive encounter in male mice.

O. Sanchez, M. Viladrich, I. Ramirez, and M. Soley (2007)
Am J Physiol Regulatory Integrative Comp Physiol 293, R1908-R1916
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S-Adenosylmethionine-dependent Protein Methylation in Mammalian Cytosol via Tyrphostin Modification by Catechol-O-methyltransferase.

R. S. Lipson and S. G. Clarke (2007)
J. Biol. Chem. 282, 31094-31102
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Transcriptional Control of Cholesterol Biosynthesis in Schwann Cells by Axonal Neuregulin 1.

M. Pertusa, C. Morenilla-Palao, C. Carteron, F. Viana, and H. Cabedo (2007)
J. Biol. Chem. 282, 28768-28778
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A Fluorescence Lifetime Based Binding Assay to Characterize Kinase Inhibitors.

C. S. Lebakken, Hee Chol Kang, and K. W. Vogel (2007)
J Biomol Screen 12, 828-841
 |  Abstract »  |  PDF »

Heparin-binding EGF-like growth factor mediates oxyhemoglobin-induced suppression of voltage-dependent potassium channels in rabbit cerebral artery myocytes.

M. Koide, P. L. Penar, B. I. Tranmer, and G. C. Wellman (2007)
Am J Physiol Heart Circ Physiol 293, H1750-H1759
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Visualizing the Dynamics of EGFR Activity and Antiglioma Therapies In vivo.

E. Arwert, S. Hingtgen, J.-L. Figueiredo, H. Bergquist, U. Mahmood, R. Weissleder, and K. Shah (2007)
Cancer Res. 67, 7335-7342
 |  Abstract »  |  Full Text »  |  PDF »

Differential Regulation of Hypoxia-Inducible Factor-1 through Receptor Tyrosine Kinase Transactivation in Vascular Smooth Muscle Cells.

M.-C. Lauzier, E. L. Page, M. D. Michaud, and D. E. Richard (2007)
Endocrinology 148, 4023-4031
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Dynamic and differential regulation of NKCC1 by calcium and cAMP in the native human colonic epithelium.

A. Reynolds, A. Parris, L. A. Evans, S. Lindqvist, P. Sharp, M. Lewis, R. Tighe, and M. R. Williams (2007)
J. Physiol. 582, 507-524
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Protein Kinase A-Independent cAMP Stimulation of Progesterone in a Luteal Cell Model Is Tyrosine Kinase Dependent but Phosphatidylinositol-3-Kinase and Mitogen-Activated Protein Kinase Independent.

E. Needle, K. Piparo, D. Cole, C. Worrall, I. Whitehead, G. Mahon, and L. T. Goldsmith (2007)
Biol Reprod 77, 147-155
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Chemopreventive Efficacy of Silymarin in Skin and Prostate Cancer.

G. Deep and R. Agarwal (2007)
Integr Cancer Ther 6, 130-145
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Enteropathogenic Escherichia coli-Induced Epidermal Growth Factor Receptor Activation Contributes to Physiological Alterations in Intestinal Epithelial Cells.

J. L. Roxas, A. Koutsouris, and V. K. Viswanathan (2007)
Infect. Immun. 75, 2316-2324
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Testosterone Activates Mitogen-Activated Protein Kinase via Src Kinase and the Epidermal Growth Factor Receptor in Sertoli Cells.

J. Cheng, S. C. Watkins, and W. H. Walker (2007)
Endocrinology 148, 2066-2074
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Activation of Epidermal Growth Factor Receptor Inhibits KCNQ2/3 Current through Two Distinct Pathways: Membrane PtdIns(4,5)P2 Hydrolysis and Channel Phosphorylation.

Q. Jia, Z. Jia, Z. Zhao, B. Liu, H. Liang, and H. Zhang (2007)
J. Neurosci. 27, 2503-2512
 |  Abstract »  |  Full Text »  |  PDF »

Lysophosphatidic Acid Promoting Corneal Epithelial Wound Healing by Transactivation of Epidermal Growth Factor Receptor.

K.-P. Xu, J. Yin, and F.-S. X. Yu (2007)
Invest. Ophthalmol. Vis. Sci. 48, 636-643
 |  Abstract »  |  Full Text »  |  PDF »

A High-Throughput Cell-Based Assay to Identify Specific Inhibitors of Transcription Factor AP-1.

K. M. Ruocco, E. I. Goncharova, M. R. Young, N. H. Colburn, J. B. McMahon, and C. J. Henrich (2007)
J Biomol Screen 12, 133-139
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EGF Receptor Activity Modulates Apoptosis Induced by Inhibition of the Proteasome of Vascular Smooth Muscle Cells.

W.-Z. Ying, H.-G. Zhang, and P. W. Sanders (2007)
J. Am. Soc. Nephrol. 18, 131-142
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Role of Tyrosine Kinase Receptors in Angiotensin II AT2 Receptor Signaling: Involvement in Neurite Outgrowth and in p42/p44mapk Activation in NG108-15 Cells.

B. Plouffe, M.-O. Guimond, H. Beaudry, and N. Gallo-Payet (2006)
Endocrinology 147, 4646-4654
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Decorin Protein Core Inhibits in Vivo Cancer Growth and Metabolism by Hindering Epidermal Growth Factor Receptor Function and Triggering Apoptosis via Caspase-3 Activation.

D. G. Seidler, S. Goldoni, C. Agnew, C. Cardi, M. L. Thakur, R. T. Owens, D. J. McQuillan, and R. V. Iozzo (2006)
J. Biol. Chem. 281, 26408-26418
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Poxviral Regulation of the Host NF-{kappa}B Response: the Vaccinia Virus M2L Protein Inhibits Induction of NF-{kappa}B Activation via an ERK2 Pathway in Virus-Infected Human Embryonic Kidney Cells..

R. Gedey, X.-L. Jin, O. Hinthong, and J. L. Shisler (2006)
J. Virol. 80, 8676-8685
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Tissue Distribution and Metabolism of the Tyrosine Kinase Inhibitor ZD6474 (Zactima) in Tumor-Bearing Nude Mice following Oral Dosing.

D. L. Gustafson, E. L. Bradshaw-Pierce, A. L. Merz, and J. A. Zirrolli (2006)
J. Pharmacol. Exp. Ther. 318, 872-880
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Role of c-Src in Human MCF7 Breast Cancer Cell Tumorigenesis.

L. Gonzalez, M. T. Agullo-Ortuno, J. M. Garcia-Martinez, A. Calcabrini, C. Gamallo, J. Palacios, A. Aranda, and J. Martin-Perez (2006)
J. Biol. Chem. 281, 20851-20864
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The emergence of ErbB2 expression in cultured rat hepatocytes correlates with enhanced and diversified EGF-mediated signaling..

L. A. Scheving, L. Zhang, M. C. Stevenson, E. S. Kwak, and W. E. Russell (2006)
Am J Physiol Gastrointest Liver Physiol 291, G16-G25
 |  Abstract »  |  Full Text »  |  PDF »

Comparison of the epidermal growth factor receptor gene and protein in primary non-small-cell-lung cancer and metastatic sites: implications for treatment with EGFR-inhibitors.

A. Italiano, F. B. Vandenbos, J. Otto, J. Mouroux, D. Fontaine, P.-Y. Marcy, N. Cardot, A. Thyss, and F. Pedeutour (2006)
Ann. Onc. 17, 981-985
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Suppression of the Phosphorylation of Receptor Tyrosine Phosphatase-{alpha} on the Src-Independent Site Tyrosine 789 by Reactive Oxygen Species.

Q. Hao, S. A. Rutherford, B. Low, and H. Tang (2006)
Mol. Pharmacol. 69, 1938-1944
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New Assignments for Multitasking Signal Transduction Inhibitors.

Z. Zhang and K. E. Meier (2006)
Mol. Pharmacol. 69, 1510-1512
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EGFR Kinase Regulates Volume-sensitive Chloride Current Elicited by Integrin Stretch via PI-3K and NADPH Oxidase in Ventricular Myocytes.

D. M. Browe and C. M. Baumgarten (2006)
J. Gen. Physiol. 127, 237-251
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A Signaling Mechanism from G{alpha}q-Protein-Coupled Metabotropic Glutamate Receptors to Gene Expression: Role of the c-Jun N-Terminal Kinase Pathway.

L. Yang, L. Mao, H. Chen, M. Catavsan, J. Kozinn, A. Arora, X. Liu, and J. Q. Wang (2006)
J. Neurosci. 26, 971-980
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Epidermal Growth Factor Receptor Overexpression Results in Increased Tumor Cell Motility In vivo Coordinately with Enhanced Intravasation and Metastasis.

C. Xue, J. Wyckoff, F. Liang, M. Sidani, S. Violini, K.-L. Tsai, Z.-Y. Zhang, E. Sahai, J. Condeelis, and J. E. Segall (2006)
Cancer Res. 66, 192-197
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Blockade of EGFR and ErbB2 by the Novel Dual EGFR and ErbB2 Tyrosine Kinase Inhibitor GW572016 Sensitizes Human Colon Carcinoma GEO Cells to Apoptosis.

Y. Zhou, S. Li, Y. P. Hu, J. Wang, J. Hauser, A. N. Conway, M. A. Vinci, L. Humphrey, E. Zborowska, J. K.V. Willson, et al. (2006)
Cancer Res. 66, 404-411
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Adenylate cyclase 5 and KCa1.1 channel are required for EGFR up-regulation of PCNA in native contractile rat basilar artery smooth muscle.

A. Ivanov, V. Gerzanich, S. Ivanova, R. DenHaese, O. Tsymbalyuk, and J. M. Simard (2006)
J. Physiol. 570, 73-84
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The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism.

G. Dasmahapatra, M. Rahmani, P. Dent, and S. Grant (2006)
Blood 107, 232-240
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Endosomal Transport of ErbB-2: Mechanism for Nuclear Entry of the Cell Surface Receptor.

D. K. Giri, M. Ali-Seyed, L.-Y. Li, D.-F. Lee, P. Ling, G. Bartholomeusz, S.-C. Wang, and M.-C. Hung (2005)
Mol. Cell. Biol. 25, 11005-11018
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Insulin-Like Growth Factor I Induces Preferential Degradation of Insulin Receptor Substrate-2 through the Phosphatidylinositol 3-Kinase Pathway in Human Neuroblastoma Cells.

B. Kim, C. M. van Golen, and E. L. Feldman (2005)
Endocrinology 146, 5350-5357
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Uncoupling between Epidermal Growth Factor Receptor and Downstream Signals Defines Resistance to the Antiproliferative Effect of Gefitinib in Bladder Cancer Cells.

W. Kassouf, C. P.N. Dinney, G. Brown, D. J. McConkey, A. J. Diehl, M. Bar-Eli, and L. Adam (2005)
Cancer Res. 65, 10524-10535
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EGFR Activation Mediates Inhibition of Axon Regeneration by Myelin and Chondroitin Sulfate Proteoglycans.

V. Koprivica, K.-S. Cho, J. B. Park, G. Yiu, J. Atwal, B. Gore, J. A. Kim, E. Lin, M. Tessier-Lavigne, D. F. Chen, et al. (2005)
Science 310, 106-110
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Increased Epidermal Growth Factor Receptor Gene Copy Number Detected by Fluorescence In Situ Hybridization Associates With Increased Sensitivity to Gefitinib in Patients With Bronchioloalveolar Carcinoma Subtypes: A Southwest Oncology Group Study.

F. R. Hirsch, M. Varella-Garcia, J. McCoy, H. West, A. C. Xavier, P. Gumerlock, P. A. Bunn Jr, W. A. Franklin, J. Crowley, and D. R. Gandara (2005)
J. Clin. Oncol. 23, 6838-6845
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Enhanced Efficacy of Radioimmunotherapy with 90Y-CHX-A''-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478.

F. T. Lee, A. J. Mountain, M. P. Kelly, C. Hall, A. Rigopoulos, T. G. Johns, F. E. Smyth, M. W. Brechbiel, E. C. Nice, A. W. Burgess, et al. (2005)
Clin. Cancer Res. 11, 7080s-7086s
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Decorin Evokes Protracted Internalization and Degradation of the Epidermal Growth Factor Receptor via Caveolar Endocytosis.

J.-X. Zhu, S. Goldoni, G. Bix, R. T. Owens, D. J. McQuillan, C. C. Reed, and R. V. Iozzo (2005)
J. Biol. Chem. 280, 32468-32479
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Posttranslational Protein Modification in Archaea.

J. Eichler and M. W. W. Adams (2005)
Microbiol. Mol. Biol. Rev. 69, 393-425
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Multiple Reaction Monitoring to Identify Sites of Protein Phosphorylation with High Sensitivity.

R. D. Unwin, J. R. Griffiths, M. K. Leverentz, A. Grallert, I. M. Hagan, and A. D. Whetton (2005)
Mol. Cell. Proteomics 4, 1134-1144
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Involvement of NADPH Oxidase Isoforms and Src Family Kinases in CD95-dependent Hepatocyte Apoptosis.

R. Reinehr, S. Becker, A. Eberle, S. Grether-Beck, and D. Haussinger (2005)
J. Biol. Chem. 280, 27179-27194
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Reorganization of ErbB Family and Cell Survival Signaling after Knock-down of ErbB2 in Colon Cancer Cells.

Y. P. Hu, S. Venkateswarlu, N. Sergina, G. Howell, P. St. Clair, L. E. Humphrey, W. Li, J. Hauser, E. Zborowska, J. K. V. Willson, et al. (2005)
J. Biol. Chem. 280, 27383-27392
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Synergy of Epidermal Growth Factor Receptor Kinase Inhibitor AG1478 and ErbB2 Kinase Inhibitor AG879 in Human Colon Carcinoma Cells Is Associated with Induction of Apoptosis.

Y. Zhou and M. G. Brattain (2005)
Cancer Res. 65, 5848-5856
 |  Abstract »  |  Full Text »  |  PDF »

Novel Role for Cyclin-dependent Kinase 2 in Neuregulin-induced Acetylcholine Receptor {epsilon} Subunit Expression in Differentiated Myotubes.

G. Lu, K. A. Seta, and D. E. Millhorn (2005)
J. Biol. Chem. 280, 21731-21738
 |  Abstract »  |  Full Text »  |  PDF »

Phase 1 Clinical and Pharmacokinetics Evaluation of Oral CI-1033 in Patients with Refractory Cancer.

J. Nemunaitis, I. Eiseman, C. Cunningham, N. Senzer, A. Williams, P. F. Lenehan, S. C. Olson, P. Bycott, M. Schlicht, R. Zentgraff, et al. (2005)
Clin. Cancer Res. 11, 3846-3853
 |  Abstract »  |  Full Text »  |  PDF »

Epidermal Growth Factor Receptor Gene and Protein and Gefitinib Sensitivity in Non-Small-Cell Lung Cancer.

F. Cappuzzo, F. R. Hirsch, E. Rossi, S. Bartolini, G. L. Ceresoli, L. Bemis, J. Haney, S. Witta, K. Danenberg, I. Domenichini, et al. (2005)
J Natl Cancer Inst 97, 643-655
 |  Abstract »  |  Full Text »  |  PDF »

Albumin Activates ERK Via EGF Receptor in Human Renal Epithelial Cells.

H. Reich, D. Tritchler, A. M. Herzenberg, Z. Kassiri, X. Zhou, W. Gao, and J. W. Scholey (2005)
J. Am. Soc. Nephrol. 16, 1266-1278
 |  Abstract »  |  Full Text »  |  PDF »

Oleate Promotes the Proliferation of Breast Cancer Cells via the G Protein-coupled Receptor GPR40.

S. Hardy, G. G. St-Onge, E. Joly, Y. Langelier, and M. Prentki (2005)
J. Biol. Chem. 280, 13285-13291
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Resensitization of P2Y Receptors by Growth Factor-Mediated Activation of the Phosphatidylinositol-3 Kinase in Retinal Glial Cells.

M. Weick, P. Wiedemann, A. Reichenbach, and A. Bringmann (2005)
Invest. Ophthalmol. Vis. Sci. 46, 1525-1532
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Cyclin D2 in Rat Granulosa Cells Requires FSH-dependent Relief from FOXO1 Repression Coupled with Positive Signals from Smad.

Y. Park, E. T. Maizels, Z. J. Feiger, H. Alam, C. A. Peters, T. K. Woodruff, T. G. Unterman, E. J. Lee, J. L. Jameson, and M. Hunzicker-Dunn (2005)
J. Biol. Chem. 280, 9135-9148
 |  Abstract »  |  Full Text »  |  PDF »

Use of mRNA- and protein-destabilizing elements to develop a highly responsive reporter system.

D. C. Voon, L. S. Subrata, S. Baltic, M. P. Leu, J. M. Whiteway, A. Wong, S. A. Knight, F. T. Christiansen, and J. M. Daly (2005)
Nucleic Acids Res. 33, e27
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PDGF receptor kinase inhibitors for the treatment of restenosis.

A. Levitzki (2005)
Cardiovasc Res 65, 581-586
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Deregulation of Cell Proliferation by Polycyclic Aromatic Hydrocarbons in Human Breast Carcinoma MCF-7 Cells Reflects Both Genotoxic and Nongenotoxic Events.

M. Pliskova, J. Vondracek, B. Vojtesek, A. Kozubik, and M. Machala (2005)
Toxicol. Sci. 83, 246-256
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Epidermal Growth Factor Receptor-deficient Mice Have Delayed Primary Endochondral Ossification Because of Defective Osteoclast Recruitment.

K. Wang, H. Yamamoto, J. R. Chin, Z. Werb, and T. H. Vu (2004)
J. Biol. Chem. 279, 53848-53856
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Cytokine-Induced Activation of Signal Transducer and Activator of Transcription in Photoreceptor Precursors Regulates Rod Differentiation in the Developing Mouse Retina.

K. D. Rhee, O. Goureau, S. Chen, and X.-J. Yang (2004)
J. Neurosci. 24, 9779-9788
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Involvement of Tumor Necrosis Factor Receptor-associated Protein 1 (TRAP1) in Apoptosis Induced by {beta}-Hydroxyisovalerylshikonin.

Y. Masuda, G. Shima, T. Aiuchi, M. Horie, K. Hori, S. Nakajo, S. Kajimoto, T. Shibayama-Imazu, and K. Nakaya (2004)
J. Biol. Chem. 279, 42503-42515
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Development of an Autocrine Neuregulin Signaling Loop with Malignant Transformation of Human Breast Epithelial Cells.

Q. Li, S. Ahmed, and J. A. Loeb (2004)
Cancer Res. 64, 7078-7085
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Adhesion-Mediated Squamous Cell Carcinoma Survival through Ligand-Independent Activation of Epidermal Growth Factor Receptor.

X. Shen and R. H. Kramer (2004)
Am. J. Pathol. 165, 1315-1329
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Tyrphostin AGL-2043 eluting stent reduces neointima formation in porcine coronary arteries.

S. Banai, S.D. Gertz, L. Gavish, M. Chorny, L. S. Perez, G. Lazarovichi, M. Ianculuvich, M. Hoffmann, M. Orlowski, G. Golomb, et al. (2004)
Cardiovasc Res 64, 165-171
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Calmodulin-mediated Activation of Akt Regulates Survival of c-Myc-overexpressing Mouse Mammary Carcinoma Cells.

T. B. Deb, C. M. Coticchia, and R. B. Dickson (2004)
J. Biol. Chem. 279, 38903-38911
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DNA Topoisomerase I As One of the Cellular Targets of Certain Tyrphostin Derivatives.

S. Bendetz-Nezer, A. Gazit, and E. Priel (2004)
Mol. Pharmacol. 66, 627-634
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The AG1478 tyrosine kinase inhibitor is an effective suppressor of leiomyoma cell growth.

A. Shushan, N. Rojansky, N. Laufer, B. Y. Klein, Z. Shlomai, R. Levitzki, Z. Hartzstark, and H. Ben-Bassat (2004)
Hum. Reprod. 19, 1957-1967
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Signal transduction of betacellulin in growth and migration of vascular smooth muscle cells.

M. Mifune, H. Ohtsu, H. Suzuki, G. D. Frank, T. Inagami, H. Utsunomiya, P. J. Dempsey, and S. Eguchi (2004)
Am J Physiol Cell Physiol 287, C807-C813
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Imaging Phosphorylation Dynamics of the Epidermal Growth Factor Receptor.

M. Offterdinger, V. Georget, A. Girod, and P. I. H. Bastiaens (2004)
J. Biol. Chem. 279, 36972-36981
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Akt Phosphorylation and Gefitinib Efficacy in Patients With Advanced Non-Small-Cell Lung Cancer.

F. Cappuzzo, E. Magrini, G. L. Ceresoli, S. Bartolini, E. Rossi, V. Ludovini, V. Gregorc, C. Ligorio, A. Cancellieri, S. Damiani, et al. (2004)
J Natl Cancer Inst 96, 1133-1141
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Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2.

J. M. Swiercz, R. Kuner, and S. Offermanns (2004)
J. Cell Biol. 165, 869-880
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Transactivation of the Insulin-Like Growth Factor-I Receptor by Angiotensin II Mediates Downstream Signaling from the Angiotensin II Type 1 Receptor to Phosphatidylinositol 3-Kinase.

P. Zahradka, B. Litchie, B. Storie, and G. Helwer (2004)
Endocrinology 145, 2978-2987
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Regional Differences in Tyrosine Kinase Receptor Signaling Components Determine Differential Growth Patterns in the Human Lens.

J. M. Maidment, G. Duncan, S. Tamiya, D. J. Collison, L. Wang, and I. M. Wormstone (2004)
Invest. Ophthalmol. Vis. Sci. 45, 1427-1435
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A Multicenter Phase I Gene Therapy Clinical Trial Involving Intraperitoneal Administration of E1A-Lipid Complex in Patients with Recurrent Epithelial Ovarian Cancer Overexpressing HER-2/neu Oncogene.

S. Madhusudan, A. Tamir, N. Bates, E. Flanagan, M. E. Gore, D. P. J. Barton, P. Harper, M. Seckl, H. Thomas, N. R. Lemoine, et al. (2004)
Clin. Cancer Res. 10, 2986-2996
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The role of ADAM protease in the tyrosine kinase-mediated trigger mechanism of ischemic preconditioning.

Y. Ichikawa, T. Miura, A. Nakano, T. Miki, Y. Nakamura, K. Tsuchihashi, and K. Shimamoto (2004)
Cardiovasc Res 62, 167-175
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Epigallocatechin-3-gallate Inhibits Epidermal Growth Factor Receptor Signaling Pathway: EVIDENCE FOR DIRECT INHIBITION OF ERK1/2 AND AKT KINASES.

J. F. Sah, S. Balasubramanian, R. L. Eckert, and E. A. Rorke (2004)
J. Biol. Chem. 279, 12755-12762
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Evidence That Tyrphostins AG10 and AG18 Are Mitochondrial Uncouplers That Alter Phosphorylation-dependent Cell Signaling.

S. P. Soltoff (2004)
J. Biol. Chem. 279, 10910-10918
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Activation of STAT Signaling Pathways and Induction of Suppressors of Cytokine Signaling (SOCS) Proteins in Mammalian Lens by Growth Factors.

S. Ebong, C.-R. Yu, D. A. Carper, A. B. Chepelinsky, and C. E. Egwuagu (2004)
Invest. Ophthalmol. Vis. Sci. 45, 872-878
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Transforming growth factor-{alpha} directly augments histidine decarboxylase and vesicular monoamine transporter 2 production in rat enterochromaffin-like cells.

H. Kazumori, S. Ishihara, M. A. K. Rumi, C. F. Ortega-Cava, Y. Kadowaki, and Y. Kinoshita (2004)
Am J Physiol Gastrointest Liver Physiol 286, G508-G514
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Gs Protein-coupled Receptor Agonists Induce Transactivation of the Epidermal Growth Factor Receptor in T84 Cells: IMPLICATIONS FOR EPITHELIAL SECRETORY RESPONSES.

L. S. Bertelsen, K. E. Barrett, and S. J. Keely (2004)
J. Biol. Chem. 279, 6271-6279
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Apigenin Induces Apoptosis through Proteasomal Degradation of HER2/neu in HER2/neu-overexpressing Breast Cancer Cells via the Phosphatidylinositol 3-Kinase/Akt-dependent Pathway.

T.-D. Way, M.-C. Kao, and J.-K. Lin (2004)
J. Biol. Chem. 279, 4479-4489
 |  Abstract »  |  Full Text »  |  PDF »

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