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Science 17 March 1995: Vol. 267. no. 5204, pp. 1662 - 1666 DOI: 10.1126/science.7886458
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Articles
Science, Vol 267, Issue 5204, 1662-1666
Copyright © 1995 by American Association for the Advancement of Science
Inhibition of ocular dominance column formation by infusion of NT-4/5 or BDNF
RJ Cabelli,
A Hohn,
and
CJ Shatz
Howard Hughes Medical Institute, University of California, Berkeley 94720.
During the development of the visual system of higher mammals, axons from the lateral geniculate nucleus (LGN) become segregated into eye-specific patches (the ocular dominance columns) within their target, layer 4 of the primary visual cortex. This occurs as a consequence of activity-dependent synaptic competition between axons representing the two eyes. The possibility that this competition could be mediated through neurotrophin-receptor interactions was tested. Infusion of neurotrophin-4/5 (NT-4/5) or brain-derived neurotrophic factor (BDNF) into cat primary visual cortex inhibited column formation within the immediate vicinity of the infusion site but not elsewhere in the visual cortex. Infusion of nerve growth factor, neurotrophin 3 (NT-3), or vehicle solution did not affect column formation. These observations implicate TrkB, the common receptor for BDNF and NT-4/5, in the segregation of LGN axons into ocular dominance columns in layer 4. Moreover, they suggest that in addition to their better known roles in the prevention of cell death, neurotrophins may also mediate the activity-dependent control of axonal branching during development of the central nervous system.
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| PDF »
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| Full Text »
| PDF »
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| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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J. Neurosci.
20, 771-782
| Abstract »
| Full Text »
| PDF »
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- A. K. McAllister (1999)
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96, 13600-13602
| Full Text »
| PDF »
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- B. Lom and S. Cohen-Cory (1999)
J. Neurosci.
19, 9928-9938
| Abstract »
| Full Text »
| PDF »
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96, 13491-13495
| Abstract »
| Full Text »
| PDF »
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96, 12893-12900
| Abstract »
| Full Text »
| PDF »
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- T. Elliott and N. R. Shadbolt (1999)
J. Neurosci.
19, 7951-7970
| Abstract »
| Full Text »
| PDF »
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- C. T. Drake, T. A. Milner, and S. L. Patterson (1999)
J. Neurosci.
19, 8009-8026
| Abstract »
| Full Text »
| PDF »
- Long-Term Enhancement of Central Synaptic Transmission by Chronic Brain-Derived Neurotrophic Factor Treatment.
- N. T. Sherwood and D. C. Lo (1999)
J. Neurosci.
19, 7025-7036
| Abstract »
| Full Text »
| PDF »
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- D. Kryl, T. Yacoubian, A. Haapasalo, E. Castren, D. Lo, and P. A. Barker (1999)
J. Neurosci.
19, 5823-5833
| Abstract »
| Full Text »
| PDF »
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- L. Boulanger and M. Poo (1999)
Science
284, 1982-1984
| Abstract »
| Full Text »
- Impairments in High-Frequency Transmission, Synaptic Vesicle Docking, and Synaptic Protein Distribution in the Hippocampus of BDNF Knockout Mice.
- L. D. Pozzo-Miller, W. Gottschalk, L. Zhang, K. McDermott, J. Du, R. Gopalakrishnan, C. Oho, Z.-H. Sheng, and B. Lu (1999)
J. Neurosci.
19, 4972-4983
| Abstract »
| Full Text »
| PDF »
- Activity-Dependent Activation of TrkB Neurotrophin Receptors in the Adult CNS.
- R. Aloyz, J. P. Fawcett, D. R. Kaplan, R. A. Murphy, and F. D. Miller (1999)
Learn. Mem.
6, 216-231
| Abstract »
| Full Text »
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- B. Berninger, A. F. Schinder, and M.-m. Poo (1999)
Learn. Mem.
6, 232-242
| Abstract »
| Full Text »
- Signaling Mechanisms Mediating BDNF Modulation of Synaptic Plasticity in the Hippocampus.
- W. A. Gottschalk, H. Jiang, N. Tartaglia, L. Feng, A. Figurov, and B. Lu (1999)
Learn. Mem.
6, 243-256
| Abstract »
| Full Text »
- Blockade of NR2B-Containing NMDA Receptors Prevents BDNF Enhancement of Glutamatergic Transmission in Hippocampal Neurons.
- R. A. Crozier, I. B. Black, and M. R. Plummer (1999)
Learn. Mem.
6, 257-266
| Abstract »
| Full Text »
- BDNF Regulates the Intrinsic Excitability of Cortical Neurons.
- N. S. Desai, L. C. Rutherford, and G. G. Turrigiano (1999)
Learn. Mem.
6, 284-291
| Abstract »
| Full Text »
- A Changing Pattern of Brain-Derived Neurotrophic Factor Expression Correlates with the Rearrangement of Fibers during Cochlear Development of Rats and Mice.
- B. Wiechers, G. Gestwa, A. Mack, P. Carroll, H.-P. Zenner, and M. Knipper (1999)
J. Neurosci.
19, 3033-3042
| Abstract »
| Full Text »
| PDF »
- Reelin Regulates the Development and Synaptogenesis of the Layer-Specific Entorhino-Hippocampal Connections.
- V. Borrell, J. A. Del Rio, S. Alcantara, M. Derer, A. Martinez, G. D'Arcangelo, K. Nakajima, K. Mikoshiba, P. Derer, T. Curran, et al. (1999)
J. Neurosci.
19, 1345-1358
| Abstract »
| Full Text »
| PDF »
- Selective Inhibition of Kindling Development by Intraventricular Administration of TrkB Receptor Body.
- D. K. Binder, M. J. Routbort, T. E. Ryan, G. D. Yancopoulos, and J. O. McNamara (1999)
J. Neurosci.
19, 1424-1436
| Abstract »
| Full Text »
| PDF »
- The role of presynaptic activity in monocular deprivation: Comparison of homosynaptic and heterosynaptic mechanisms.
- B. S. Blais, H. Z. Shouval, and L. N. Cooper (1999)
PNAS
96, 1083-1087
| Abstract »
| Full Text »
| PDF »
- NMDA Receptor-Mediated Refinement of a Transient Retinotectal Projection during Development Requires Nitric Oxide.
- A. F. Ernst, H. H. Wu, E. E. El-Fakahany, and S. C. McLoon (1999)
J. Neurosci.
19, 229-235
| Abstract »
| Full Text »
| PDF »
- Stable Properties of Spontaneous EPSCs and Miniature Retinal EPSCs during the Development of ON/OFF Sublamination in the Ferret Lateral Geniculate Nucleus.
- C. D. Hohnke and M. Sur (1999)
J. Neurosci.
19, 236-247
| Abstract »
| Full Text »
| PDF »
- Establishment of Patterned Thalamocortical Connections Does Not Require Nitric Oxide Synthase.
- E. M. Finney and C. J. Shatz (1998)
J. Neurosci.
18, 8826-8838
| Abstract »
| Full Text »
| PDF »
- Neurotrophins Induce Formation of Functional Excitatory and Inhibitory Synapses between Cultured Hippocampal Neurons.
- C. Vicario-Abejon, C. Collin, R. D. G. McKay, and M. Segal (1998)
J. Neurosci.
18, 7256-7271
| Abstract »
| Full Text »
| PDF »
- TrkB and TrkC Signaling Are Required for Maturation and Synaptogenesis of Hippocampal Connections.
- A. Martinez, S. Alcantara, V. Borrell, J. A. Del Rio, J. Blasi, R. Otal, N. Campos, A. Boronat, M. Barbacid, I. Silos-Santiago, et al. (1998)
J. Neurosci.
18, 7336-7350
| Abstract »
| Full Text »
| PDF »
- Presynaptic Modulation of Synaptic Transmission and Plasticity by Brain-Derived Neurotrophic Factor in the Developing Hippocampus.
- W. Gottschalk, L. D. Pozzo-Miller, A. Figurov, and B. Lu (1998)
J. Neurosci.
18, 6830-6839
| Abstract »
| Full Text »
| PDF »
- Cerebellar Brain-Derived Neurotrophic Factor-TrkB Defect Associated with Impairment of Eyeblink Conditioning in Stargazer Mutant Mice.
- X. Qiao, L. Chen, H. Gao, S. Bao, F. Hefti, R. F. Thompson, and B. Knusel (1998)
J. Neurosci.
18, 6990-6999
| Abstract »
| Full Text »
| PDF »
- Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity.
- E. S. Levine, R. A. Crozier, I. B. Black, and M. R. Plummer (1998)
PNAS
95, 10235-10239
| Abstract »
| Full Text »
| PDF »
- Neurotrophins induce release of neurotrophins by the regulated secretory pathway.
- A. Kruttgen, J. C. Moller, J. V. Heymach Jr., and E. M. Shooter (1998)
PNAS
95, 9614-9619
| Abstract »
| Full Text »
| PDF »
- Competition for Neurotrophic Factors: Ocular Dominance Columns.
- T. Elliott and N. R. Shadbolt (1998)
J. Neurosci.
18, 5850-5858
| Abstract »
| Full Text »
| PDF »
- cAMP-Mediated Regulation of Neurotrophin-Induced Collapse of Nerve Growth Cones.
- Q. Wang and J. Q. Zheng (1998)
J. Neurosci.
18, 4973-4984
| Abstract »
| Full Text »
| PDF »
- Localized Synaptic Actions of Neurotrophin-4.
- X.-h. Wang, B. Berninger, and M.-m. Poo (1998)
J. Neurosci.
18, 4985-4992
| Abstract »
| Full Text »
| PDF »
- Involvement of Distinct Pioneer Neurons in the Formation of Layer-Specific Connections in the Hippocampus.
- H. Super, A. Martinez, J. A. Del Rio, and E. Soriano (1998)
J. Neurosci.
18, 4616-4626
| Abstract »
| Full Text »
| PDF »
- Granule Neuron Regulation of Purkinje Cell Development: Striking a Balance Between Neurotrophin and Glutamate Signaling.
- M. E. Morrison and C. A. Mason (1998)
J. Neurosci.
18, 3563-3573
| Abstract »
| Full Text »
| PDF »
- Brain-Derived Neurotrophic Factor Modulates the Development of the Dopaminergic Network in the Rodent Retina.
- A. Cellerino, G. Pinzon-Duarte, P. Carroll, and K. Kohler (1998)
J. Neurosci.
18, 3351-3362
| Abstract »
| Full Text »
| PDF »
- Functional Evidence that BDNF Is an Anterograde Neuronal Trophic Factor in the CNS.
- J. P. Fawcett, S. X. Bamji, C. G. Causing, R. Aloyz, A. R. Ase, T. A. Reader, J. H. McLean, and F. D. Miller (1998)
J. Neurosci.
18, 2808-2821
| Abstract »
| Full Text »
| PDF »
- Contributions of the Optic Tectum and the Retina as Sources of Brain-Derived Neurotrophic Factor for Retinal Ganglion Cells in the Chick Embryo.
- K.-H. Herzog and C. S. von Bartheld (1998)
J. Neurosci.
18, 2891-2906
| Abstract »
| Full Text »
| PDF »
- Hyperinnervation of Neuromuscular Junctions Caused by GDNF Overexpression in Muscle.
- Q. T. Nguyen, A. S. Parsadanian, W. D. Snider, and J. W. Lichtman (1998)
Science
279, 1725-1729
| Abstract »
| Full Text »
- Retrograde Signaling in the Development and Modification of Synapses.
- R. M. FITZSIMONDS and M.-M. POO (1998)
Physiol Rev
78, 143-170
| Abstract »
| Full Text »
| PDF »
- Differential Effects of Abnormal Tactile Experience on Shaping Representation Patterns in Developing and Adult Motor Cortex.
- G. W. Huntley (1997)
J. Neurosci.
17, 9220-9232
| Abstract »
| Full Text »
| PDF »
- Neurotrophin release by neurotrophins: Implications for activity-dependent neuronal plasticity.
- M. Canossa, O. Griesbeck, B. Berninger, G. Campana, R. Kolbeck, and H. Thoenen (1997)
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94, 13279-13286
| Abstract »
| Full Text »
| PDF »
- A model of ocular dominance column development by competition for trophic factor.
- A. E. Harris, G. B. Ermentrout, and S. L. Small (1997)
PNAS
94, 9944-9949
| Abstract »
| Full Text »
| PDF »
- Cellular Mechanisms of Visual Cortical Plasticity: A Game of Cat and Mouse.
- J. A. Gordon (1997)
Learn. Mem.
4, 245-261
| PDF »
- Brain-Derived Neurotrophic Factor Enhances Long-Term Potentiation in Rat Visual Cortex.
- Y. Akaneya, T. Tsumoto, S. Kinoshita, and H. Hatanaka (1997)
J. Neurosci.
17, 6707-6716
| Abstract »
| Full Text »
| PDF »
- Brain-Derived Neurotrophic Factor Mediates the Activity-Dependent Regulation of Inhibition in Neocortical Cultures.
- L. C. Rutherford, A. DeWan, H. M. Lauer, and G. G. Turrigiano (1997)
J. Neurosci.
17, 4527-4535
| Abstract »
| Full Text »
| PDF »
- TrkB Signaling Is Required for Postnatal Survival of CNS Neurons and Protects Hippocampal and Motor Neurons from Axotomy-Induced Cell Death.
- S. Alcantara, J. Frisen, J. A. del Rio, E. Soriano, M. Barbacid, and I. Silos-Santiago (1997)
J. Neurosci.
17, 3623-3633
| Abstract »
| Full Text »
| PDF »
- Stop and Branch Behaviors of Geniculocortical Axons: A Time-Lapse Study in Organotypic Cocultures.
- N. Yamamoto, S. Higashi, and K. Toyama (1997)
J. Neurosci.
17, 3653-3663
| Abstract »
| Full Text »
| PDF »
- Activity-Dependent Expression of NT-3 in Muscle Cells in Culture: Implications in the Development of Neuromuscular Junctions.
- K. Xie, T. Wang, P. Olafsson, K. Mizuno, and B. Lu (1997)
J. Neurosci.
17, 2947-2958
| Abstract »
| Full Text »
| PDF »
- Neurotrophins Suppress Apoptosis Induced by Deafferentation of an Avian Motor-Cortical Region.
- F. Johnson, S. E. Hohmann, P. S. DiStefano, and S. W. Bottjer (1997)
J. Neurosci.
17, 2101-2111
| Abstract »
| Full Text »
| PDF »
- Changing Patterns of Expression and Subcellular Localization of TrkB in the Developing Visual System.
- R. J. Cabelli, K. L. Allendoerfer, M. J. Radeke, A. A. Welcher, S. C. Feinstein, and C. J. Shatz (1996)
J. Neurosci.
16, 7965-7980
| Abstract »
| Full Text »
| PDF »
- TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons..
- L Minichiello and R Klein (1996)
Genes & Dev.
10, 2849-2858
| Abstract »
| PDF »
- The Regulated Secretion and Vectorial Targeting of Neurotrophins in Neuroendocrine and Epithelial Cells.
- J. V. Heymach Jr., A. Kruttgen, U. Suter, and E. M. Shooter (1996)
J. Biol. Chem.
271, 25430-25437
| Abstract »
| Full Text »
| PDF »
- Upregulation of BDNF mRNA Expression in the Barrel Cortex of Adult Mice after Sensory Stimulation.
- N. Rocamora, E. Welker, M. Pascual, and E. Soriano (1996)
J. Neurosci.
16, 4411-4419
| Abstract »
| Full Text »
| PDF »
- Brain-Derived Neurotrophic Factor and Neurotrophin-4/5 Stimulate Growth of Axonal Branches from Regenerating Retinal Ganglion Cells.
- H. Sawai, D. B. Clarke, P. Kittlerova, G. M. Bray, and A. J. Aguayo (1996)
J. Neurosci.
16, 3887-3894
| Abstract »
| Full Text »
| PDF »
- Neurotrophins and the Synapse.
- S. Finkbeiner (1996)
Neuroscientist
2, 139-142
| Abstract »
| PDF »
- Combination of Gene Targeting and Gene Transfer by Adenoviral Vectors in the Analysis of Neurotrophin-mediated Neuronal Plasticity.
- O. Griesbeck, M. Korte, V. Staiger, C. Gravel, P. Carroll, T. Bonhoeffer, and H. Thoenen (1996)
Cold Spring Harb Symp Quant Biol
61, 77-83
| Abstract »
| PDF »
- Neurotrophins in Cortical Development.
- D.R. Riddle, A.K. McAllister, D.C. Lo, and L.C. Katz (1996)
Cold Spring Harb Symp Quant Biol
61, 85-93
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