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Science 17 March 1995:
Vol. 267. no. 5204, pp. 1643 - 1645
DOI: 10.1126/science.7886452

Articles

Science, Vol 267, Issue 5204, 1643-1645
Copyright © 1995 by American Association for the Advancement of Science


articles

Sodefrin: a female-attracting peptide pheromone in newt cloacal glands

S Kikuyama, F Toyoda, Y Ohmiya, K Matsuda, S Tanaka, and H Hayashi

Department of Biology, School of Education, Waseda University, Tokyo, Japan.

A decapeptide called sodefrin was isolated from the abdominal gland of the cloaca of the male red-bellied newt, Cynops pyrrhogaster. The native peptide, as well as the synthetic one, had a female-attracting activity. Sodefrin was found in the apical portion of the epithelial cells of the abdominal gland. Sodefrin is apparently species specific because it did not attract females of Cynops ensicauda. This is the first amphibian pheromone to be identified and the first peptide pheromone identified in a vertebrate.


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