Related Content
Search Google Scholar for:
|
|
Science 17 February 1995: Vol. 267. no. 5200, pp. 1018 - 1021 DOI: 10.1126/science.7863327
|
|
Articles
Science, Vol 267, Issue 5200, 1018-1021
Copyright © 1995 by American Association for the Advancement of Science
Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD
O Halevy,
BG Novitch,
DB Spicer,
SX Skapek,
J Rhee,
GJ Hannon,
D Beach,
and
AB Lassar
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.
Skeletal muscle differentiation entails the coordination of muscle-specific gene expression and terminal withdrawal from the cell cycle. This cell cycle arrest in the G0 phase requires the retinoblastoma tumor suppressor protein (Rb). The function of Rb is negatively regulated by cyclin-dependent kinases (Cdks), which are controlled by Cdk inhibitors. Expression of MyoD, a skeletal muscle-specific transcriptional regulator, activated the expression of the Cdk inhibitor p21 during differentiation of murine myocytes and in nonmyogenic cells. MyoD-mediated induction of p21 did not require the tumor suppressor protein p53 and correlated with cell cycle withdrawal. Thus, MyoD may induce terminal cell cycle arrest during skeletal muscle differentiation by increasing the expression of p21.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
- Distinct Effects of Hedgehog Signaling on Neuronal Fate Specification and Cell Cycle Progression in the Embryonic Mouse Retina.
- K. Sakagami, L. Gan, and X.-J. Yang (2009)
J. Neurosci.
29, 6932-6944
| Abstract »
| Full Text »
| PDF »
- Control of the Reversibility of Cellular Quiescence by the Transcriptional Repressor HES1.
- L. Sang, H. A. Coller, and J. M. Roberts (2008)
Science
321, 1095-1100
| Abstract »
| Full Text »
| PDF »
- PD98059 enhances C2 myoblast differentiation through p38 MAPK activation: a novel role for PD98059.
- N. Al-Shanti and C. E Stewart (2008)
J. Endocrinol.
198, 243-252
| Abstract »
| Full Text »
| PDF »
- Nerve Growth Factor Regulation of Cyclin D1 in PC12 Cells through a p21RAS Extracellular Signal-regulated Kinase Pathway Requires Cooperative Interactions between Sp1 and Nuclear Factor-{kappa}B.
- F. Marampon, M. C. Casimiro, M. Fu, M. J. Powell, V. M. Popov, J. Lindsay, B. M. Zani, C. Ciccarelli, G. Watanabe, R. J. Lee, et al. (2008)
Mol. Biol. Cell
19, 2566-2578
| Abstract »
| Full Text »
| PDF »
- Ex Vivo Simulation of the Action of Antileukemia Drugs by Measuring Apoptosis-Related mRNA in Blood.
- M. Mitsuhashi, K. Endo, K. Obara, H. Izutsu, T. Ishida, N. Chikatsu, and A. Shinagawa (2008)
Clin. Chem.
54, 673-681
| Abstract »
| Full Text »
| PDF »
- Defining the transcriptional signature of skeletal muscle stem cells.
- Z. Yablonka-Reuveni, K. Day, A. Vine, and G. Shefer (2008)
J Anim Sci
86, E207-E216
| Abstract »
| Full Text »
| PDF »
- Hes6 Controls Cell Proliferation via Interaction with cAMP-response Element-binding Protein-binding Protein in the Promyelocytic Leukemia Nuclear Body.
- B. Eun, Y. Lee, S. Hong, J. Kim, H.-W. Lee, K. Kim, W. Sun, and H. Kim (2008)
J. Biol. Chem.
283, 5939-5949
| Abstract »
| Full Text »
| PDF »
- Gene profiling of skeletal muscle in an amyotrophic lateral sclerosis mouse model.
- J.-L. Gonzalez de Aguilar, C. Niederhauser-Wiederkehr, B. Halter, M. De Tapia, F. Di Scala, P. Demougin, L. Dupuis, M. Primig, V. Meininger, and J.-P. Loeffler (2008)
Physiol Genomics
32, 207-218
| Abstract »
| Full Text »
| PDF »
- Tendons of myostatin-deficient mice are small, brittle, and hypocellular.
- C. L. Mendias, K. I. Bakhurin, and J. A. Faulkner (2008)
PNAS
105, 388-393
| Abstract »
| Full Text »
| PDF »
- Pulse Inhibition of Histone Deacetylases Induces Complete Resistance to Oxidative Death in Cortical Neurons without Toxicity and Reveals a Role for Cytoplasmic p21waf1/cip1 in Cell Cycle-Independent Neuroprotection.
- B. Langley, M. A. D'Annibale, K. Suh, I. Ayoub, A. Tolhurst, B. Bastan, L. Yang, B. Ko, M. Fisher, S. Cho, et al. (2008)
J. Neurosci.
28, 163-176
| Abstract »
| Full Text »
| PDF »
- Nuclear Receptor Hepatocyte Nuclear Factor 4{alpha}1 Competes with Oncoprotein c-Myc for Control of the p21/WAF1 Promoter.
- W. W. Hwang-Verslues and F. M. Sladek (2008)
Mol. Endocrinol.
22, 78-90
| Abstract »
| Full Text »
| PDF »
- pRb-Dependent Cyclin D3 Protein Stabilization Is Required for Myogenic Differentiation.
- F. De Santa, S. Albini, E. Mezzaroma, L. Baron, A. Felsani, and M. Caruso (2007)
Mol. Cell. Biol.
27, 7248-7265
| Abstract »
| Full Text »
| PDF »
- The RhoA effector mDiaphanous regulates MyoD expression and cell cycle progression via SRF-dependent and SRF-independent pathways.
- S. D. Gopinath, S. Narumiya, and J. Dhawan (2007)
J. Cell Sci.
120, 3086-3098
| Abstract »
| Full Text »
| PDF »
- Proneural Basic Helix-Loop-Helix Proteins and Epidermal Growth Factor Receptor Signaling Coordinately Regulate Cell Type Specification and cdk Inhibitor Expression during Development.
- M. J. Sukhanova, D. K. Deb, G. M. Gordon, M. T. Matakatsu, and W. Du (2007)
Mol. Cell. Biol.
27, 2987-2996
| Abstract »
| Full Text »
| PDF »
- Critical requirement for cell cycle inhibitors in sustaining nonproliferative states.
- D. Pajalunga, A. Mazzola, A. M. Salzano, M. G. Biferi, G. De Luca, and M. Crescenzi (2007)
J. Cell Biol.
176, 807-818
| Abstract »
| Full Text »
| PDF »
- Muscle cachexia is regulated by a p53-PW1/Peg3-dependent pathway.
- M. Schwarzkopf, D. Coletti, D. Sassoon, and G. Marazzi (2006)
Genes & Dev.
20, 3440-3452
| Abstract »
| Full Text »
| PDF »
- Age differences in cyclin-dependent kinase inhibitor expression and rb hyperphosphorylation in human corneal endothelial cells..
- K. Enomoto, T. Mimura, D. L. Harris, and N. C. Joyce (2006)
Invest. Ophthalmol. Vis. Sci.
47, 4330-4340
| Abstract »
| Full Text »
| PDF »
- Skeletal muscle repair in a mouse model of nemaline myopathy.
- D. Sanoudou, M. A. Corbett, M. Han, M. Ghoddusi, M.-A. T. Nguyen, N. Vlahovich, E. C. Hardeman, and A. H. Beggs (2006)
Hum. Mol. Genet.
15, 2603-2612
| Abstract »
| Full Text »
| PDF »
- Pharmacologic inhibition of cyclin-dependent kinase 4/6 activity arrests proliferation in myoblasts and rhabdomyosarcoma-derived cells.
- R. Saab, J. L. Bills, A. P. Miceli, C. M. Anderson, J. D. Khoury, D. W. Fry, F. Navid, P. J. Houghton, and S. X. Skapek (2006)
Mol. Cancer Ther.
5, 1299-1308
| Abstract »
| Full Text »
| PDF »
- A novel role for lbx1 in Xenopus hypaxial myogenesis.
- B. L. Martin and R. M. Harland (2006)
Development
133, 195-208
| Abstract »
| Full Text »
| PDF »
- Activation of RNA metabolism-related genes in mouse but not human tissues deficient in SMN.
- R. Olaso, V. Joshi, J. Fernandez, N. Roblot, S. Courageot, J. P. Bonnefont, and J. Melki (2006)
Physiol Genomics
24, 97-104
| Abstract »
| Full Text »
| PDF »
- Expression of the EWS/FLI-1 Oncogene in Murine Primary Bone-Derived Cells Results in EWS/FLI-1-Dependent, Ewing Sarcoma-Like Tumors.
- Y. Castillero-Trejo, S. Eliazer, L. Xiang, J. A. Richardson, and R. L. Ilaria Jr. (2005)
Cancer Res.
65, 8698-8705
| Abstract »
| Full Text »
| PDF »
- Nandrolone decanoate modulates cell cycle regulation in functionally overloaded rat soleus muscle.
- J. M. McClung, K. A. Mehl, R. W. Thompson, L. L. Lowe, and J. A. Carson (2005)
Am J Physiol Regulatory Integrative Comp Physiol
288, R1543-R1552
| Abstract »
| Full Text »
| PDF »
- The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.
- J. Mantela, Z. Jiang, J. Ylikoski, B. Fritzsch, E. Zacksenhaus, and U. Pirvola (2005)
Development
132, 2377-2388
| Abstract »
| Full Text »
| PDF »
- A steroidogenic cell line with differentiation potential from mouse granulosa cells, transfected with Ad4BP and SV40 large T antigen genes.
- Y Kamei, Y Aoyama, T Fujimoto, N Kenmotsu, C Kishi, M Koushi, S Sugano, K Morohashi, R Kamiyama, and R Asakai (2005)
J. Endocrinol.
185, 187-195
| Abstract »
| Full Text »
| PDF »
- Sequestration of pRb by Cyclin D3 Causes Intranuclear Reorganization of Lamin A/C during Muscle Cell Differentiation.
- I. Mariappan and V. K. Parnaik (2005)
Mol. Biol. Cell
16, 1948-1960
| Abstract »
| Full Text »
| PDF »
- p21WAF1/CIP1 Selectively Controls the Transcriptional Activity of Estrogen Receptor {alpha}.
- A. Fritah, C. Saucier, J. Mester, G. Redeuilh, and M. Sabbah (2005)
Mol. Cell. Biol.
25, 2419-2430
| Abstract »
| Full Text »
| PDF »
- Membrane Structure Modulation, Protein Kinase C{alpha} Activation, and Anticancer Activity of Minerval.
- J. Martinez, O. Vogler, J. Casas, F. Barcelo, R. Alemany, J. Prades, T. Nagy, C. Baamonde, P. G. Kasprzyk, S. Teres, et al. (2005)
Mol. Pharmacol.
67, 531-540
| Abstract »
| Full Text »
| PDF »
- Sharp-1/DEC2 Inhibits Skeletal Muscle Differentiation through Repression of Myogenic Transcription Factors.
- S. Azmi, A. Ozog, and R. Taneja (2004)
J. Biol. Chem.
279, 52643-52652
| Abstract »
| Full Text »
| PDF »
- Use of a Randomized Hybrid Ribozyme Library for Identification of Genes Involved in Muscle Differentiation.
- R. Wadhwa, T. Yaguchi, K. Kaur, E. Suyama, H. Kawasaki, K. Taira, and S. C. Kaul (2004)
J. Biol. Chem.
279, 51622-51629
| Abstract »
| Full Text »
| PDF »
- Id Family of Transcription Factors and Vascular Lesion Formation.
- S. Forrest and C. McNamara (2004)
Arterioscler. Thromb. Vasc. Biol.
24, 2014-2020
| Abstract »
| Full Text »
| PDF »
- Sox15 Is Required for Skeletal Muscle Regeneration.
- H.-J. Lee, W. Goring, M. Ochs, C. Muhlfeld, G. Steding, I. Paprotta, W. Engel, and I. M. Adham (2004)
Mol. Cell. Biol.
24, 8428-8436
| Abstract »
| Full Text »
| PDF »
- Modulation of acto-myosin contractility in skeletal muscle myoblasts uncouples growth arrest from differentiation.
- J. Dhawan and D. M. Helfman (2004)
J. Cell Sci.
117, 3735-3748
| Abstract »
| Full Text »
| PDF »
- In vivo expression patterns of MyoD, p21, and Rb proteins in myonuclei and satellite cells of denervated rat skeletal muscle.
- M. Ishido, K. Kami, and M. Masuhara (2004)
Am J Physiol Cell Physiol
287, C484-C493
| Abstract »
| Full Text »
| PDF »
- N-Terminal Ubiquitination of Extracellular Signal-Regulated Kinase 3 and p21 Directs Their Degradation by the Proteasome.
- P. Coulombe, G. Rodier, E. Bonneil, P. Thibault, and S. Meloche (2004)
Mol. Cell. Biol.
24, 6140-6150
| Abstract »
| Full Text »
| PDF »
- Tissue-specific G1-phase cell-cycle arrest prior to terminal differentiation in Dictyostelium.
- G. Chen, G. Shaulsky, and A. Kuspa (2004)
Development
131, 2619-2630
| Abstract »
| Full Text »
| PDF »
- Hypoxia Inhibits Myogenic Differentiation through Accelerated MyoD Degradation.
- A. Di Carlo, R. De Mori, F. Martelli, G. Pompilio, M. C. Capogrossi, and A. Germani (2004)
J. Biol. Chem.
279, 16332-16338
| Abstract »
| Full Text »
| PDF »
- Overexpression of Serum Amyloid A-Activating Factor 1 Inhibits Cell Proliferation by the Induction of Cyclin-Dependent Protein Kinase Inhibitor p21WAF-1/Cip-1/Sdi-1 Expression.
- A. Ray, A. Shakya, D. Kumar, and B. K. Ray (2004)
J. Immunol.
172, 5006-5015
| Abstract »
| Full Text »
| PDF »
- Basic Helix-Loop-Helix Proteins Bind to TrkB and p21Cip1 Promoters Linking Differentiation and Cell Cycle Arrest in Neuroblastoma Cells.
- Y. Liu, M. Encinas, J. X. Comella, M. Aldea, and C. Gallego (2004)
Mol. Cell. Biol.
24, 2662-2672
| Abstract »
| Full Text »
| PDF »
- The Yeast Split-Ubiquitin Membrane Protein Two-Hybrid Screen Identifies BAP31 as a Regulator of the Turnover of Endoplasmic Reticulum-Associated Protein Tyrosine Phosphatase-Like B.
- B. Wang, J. Pelletier, M. J. Massaad, A. Herscovics, and G. C. Shore (2004)
Mol. Cell. Biol.
24, 2767-2778
| Abstract »
| Full Text »
| PDF »
- The "CholesteROR" Protective Pathway in the Vascular System.
- F. Boukhtouche, J. Mariani, and A. Tedgui (2004)
Arterioscler. Thromb. Vasc. Biol.
24, 637-643
| Abstract »
| Full Text »
| PDF »
- Mutant MyoD Lacking Cdc2 Phosphorylation Sites Delays M-Phase Entry.
- L. A. J. Tintignac, V. Sirri, M. P. Leibovitch, Y. Lecluse, M. Castedo, D. Metivier, G. Kroemer, and S. A. Leibovitch (2004)
Mol. Cell. Biol.
24, 1809-1821
| Abstract »
| Full Text »
| PDF »
- Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization.
- R. C. J. LANGEN, J. L. J. VAN DER VELDEN, A. M. W. J. SCHOLS, M. C. J. M. KELDERS, E. F. M. WOUTERS, and Y. M. W. JANSSEN-HEININGER (2004)
FASEB J
18, 227-237
| Abstract »
| Full Text »
| PDF »
- p57Kip2 Regulates Actin Dynamics by Binding and Translocating LIM-kinase 1 to the Nucleus.
- T. Yokoo, H. Toyoshima, M. Miura, Y. Wang, K. T. Iida, H. Suzuki, H. Sone, H. Shimano, T. Gotoda, S. Nishimori, et al. (2003)
J. Biol. Chem.
278, 52919-52923
| Abstract »
| Full Text »
| PDF »
- Reciprocal Inhibition between MyoD and STAT3 in the Regulation of Growth and Differentiation of Myoblasts.
- Y. Kataoka, I. Matsumura, S. Ezoe, S. Nakata, E. Takigawa, Y. Sato, A. Kawasaki, T. Yokota, K. Nakajima, A. Felsani, et al. (2003)
J. Biol. Chem.
278, 44178-44187
| Abstract »
| Full Text »
| PDF »
- FGF-2 Antagonizes the TGF-{beta}1-Mediated Induction of Pericyte {alpha}-Smooth Muscle Actin Expression: A Role for Myf-5 and Smad-Mediated Signaling Pathways.
- M. Papetti, J. Shujath, K. N. Riley, and I. M. Herman (2003)
Invest. Ophthalmol. Vis. Sci.
44, 4994-5005
| Abstract »
| Full Text »
| PDF »
- p21 is essential for normal myogenic progenitor cell function in regenerating skeletal muscle.
- T. J. Hawke, A. P. Meeson, N. Jiang, S. Graham, K. Hutcheson, J. M. DiMaio, and D. J. Garry (2003)
Am J Physiol Cell Physiol
285, C1019-C1027
| Abstract »
| Full Text »
| PDF »
- Mirk/dyrk1B Is a Rho-induced Kinase Active in Skeletal Muscle Differentiation.
- X. Deng, D. Z. Ewton, B. Pawlikowski, M. Maimone, and E. Friedman (2003)
J. Biol. Chem.
278, 41347-41354
| Abstract »
| Full Text »
| PDF »
- A p53-independent G1 Cell Cycle Checkpoint Induced by the Suppression of Protein Kinase C {alpha} and {theta} Isoforms.
- L. Deeds, S. Teodorescu, M. Chu, Q. Yu, and C.-Y. Chen (2003)
J. Biol. Chem.
278, 39782-39793
| Abstract »
| Full Text »
| PDF »
- Role of Metalloprotease Disintegrin ADAM12 in Determination of Quiescent Reserve Cells during Myogenic Differentiation In Vitro.
- Y. Cao, Z. Zhao, J. Gruszczynska-Biegala, and A. Zolkiewska (2003)
Mol. Cell. Biol.
23, 6725-6738
| Abstract »
| Full Text »
| PDF »
- SPRR1B overexpression enhances entry of cells into the G0 phase of the cell cycle.
- Y. Tesfaigzi, P. S. Wright, and S. A. Belinsky (2003)
Am J Physiol Lung Cell Mol Physiol
285, L889-L898
| Abstract »
| Full Text »
| PDF »
- GATA-1-Mediated Proliferation Arrest during Erythroid Maturation.
- M. Rylski, J. J. Welch, Y.-Y. Chen, D. L. Letting, J. A. Diehl, L. A. Chodosh, G. A. Blobel, and M. J. Weiss (2003)
Mol. Cell. Biol.
23, 5031-5042
| Abstract »
| Full Text »
| PDF »
- Rapid Turnover of Extracellular Signal-Regulated Kinase 3 by the Ubiquitin-Proteasome Pathway Defines a Novel Paradigm of Mitogen-Activated Protein Kinase Regulation during Cellular Differentiation.
- P. Coulombe, G. Rodier, S. Pelletier, J. Pellerin, and S. Meloche (2003)
Mol. Cell. Biol.
23, 4542-4558
| Abstract »
| Full Text »
| PDF »
- The Mitogen-activated Protein Kinase Cascade Promotes Myoblast Cell Survival by Stabilizing the Cyclin-dependent Kinase Inhibitor, p21WAF1 Protein.
- O. Ostrovsky and E. Bengal (2003)
J. Biol. Chem.
278, 21221-21231
| Abstract »
| Full Text »
| PDF »
- Early Posthatch Feeding Stimulates Satellite Cell Proliferation and Skeletal Muscle Growth in Turkey Poults.
- O. Halevy, Y. Nadel, M. Barak, I. Rozenboim, and D. Sklan (2003)
J. Nutr.
133, 1376-1382
| Abstract »
| Full Text »
| PDF »
- MyoD Stimulates RB Promoter Activity via the CREB/p300 Nuclear Transduction Pathway.
- A. Magenta, C. Cenciarelli, F. De Santa, P. Fuschi, F. Martelli, M. Caruso, and A. Felsani (2003)
Mol. Cell. Biol.
23, 2893-2906
| Abstract »
| Full Text »
| PDF »
- Myofibroblast Differentiation by Transforming Growth Factor-beta 1 Is Dependent on Cell Adhesion and Integrin Signaling via Focal Adhesion Kinase.
- V. J. Thannickal, D. Y. Lee, E. S. White, Z. Cui, J. M. Larios, R. Chacon, J. C. Horowitz, R. M. Day, and P. E. Thomas (2003)
J. Biol. Chem.
278, 12384-12389
| Abstract »
| Full Text »
| PDF »
- Human Papillomavirus Type 31 E5 Protein Supports Cell Cycle Progression and Activates Late Viral Functions upon Epithelial Differentiation.
- F. Fehrmann, D. J. Klumpp, and L. A. Laimins (2003)
J. Virol.
77, 2819-2831
| Abstract »
| Full Text »
| PDF »
- Basic Helix-Loop-Helix Transcription Factor Epicardin/Capsulin/Pod-1 Suppresses Differentiation by Negative Regulation of Transcription.
- N. Funato, K. Ohyama, T. Kuroda, and M. Nakamura (2003)
J. Biol. Chem.
278, 7486-7493
| Abstract »
| Full Text »
| PDF »
- Alteration of Mesodermal Cell Differentiation by EWS/FLI-1, the Oncogene Implicated in Ewing's Sarcoma.
- S. Eliazer, J. Spencer, D. Ye, E. Olson, and R. L. Ilaria Jr. (2003)
Mol. Cell. Biol.
23, 482-492
| Abstract »
| Full Text »
| PDF »
- A single cdk inhibitor, p27Xic1, functions beyond cell cycle regulation to promote muscle differentiation in Xenopus.
- A. E. Vernon and A. Philpott (2003)
Development
130, 71-83
| Abstract »
| Full Text »
| PDF »
- The cdk inhibitor p27Xic1 is required for differentiation of primary neurones in Xenopus.
- A. E. Vernon, C. Devine, and A. Philpott (2003)
Development
130, 85-92
| Abstract »
| Full Text »
| PDF »
- Myostatin Inhibits Myoblast Differentiation by Down-regulating MyoD Expression.
- B. Langley, M. Thomas, A. Bishop, M. Sharma, S. Gilmour, and R. Kambadur (2002)
J. Biol. Chem.
277, 49831-49840
| Abstract »
| Full Text »
| PDF »
- In Vivo Activation of STAT3 Signaling in Satellite Cells and Myofibers in Regenerating Rat Skeletal Muscles.
- K. Kami and E. Senba (2002)
J. Histochem. Cytochem.
50, 1579-1589
| Abstract »
| Full Text »
| PDF »
- Mutant DMPK 3'-UTR transcripts disrupt C2C12 myogenic differentiation by compromising MyoD.
- J. D. Amack, S. R. Reagan, and M. S. Mahadevan (2002)
J. Cell Biol.
159, 419-429
| Abstract »
| Full Text »
| PDF »
- P21WAF1 CONTROL OF EPITHELIAL CELL CYCLE AND CELL FATE.
- W. C. Weinberg and M. F. Denning (2002)
Critical Reviews in Oral Biology & Medicine
13, 453-464
| Abstract »
| Full Text »
| PDF »
- The Small Heat Shock Protein alpha B-crystallin Negatively Regulates Apoptosis during Myogenic Differentiation by Inhibiting Caspase-3 Activation.
- M. C. Kamradt, F. Chen, S. Sam, and V. L. Cryns (2002)
J. Biol. Chem.
277, 38731-38736
| Abstract »
| Full Text »
| PDF »
- Coordination of the cell cycle is an important determinant of the syndrome of acute renal failure.
- J. Megyesi, L. Andrade, J. M. Vieira Jr., R. L. Safirstein, and P. M. Price (2002)
Am J Physiol Renal Physiol
283, F810-F816
| Abstract »
| Full Text »
| PDF »
- Activation of the Jak3 pathway is associated with granulocytic differentiation of myeloid precursor cells.
- S. G. Rane, J. K. Mangan, A. Amanullah, B. C. Wong, R. K. Vora, D. A. Liebermann, B. Hoffman, X. Grana, and E. P. Reddy (2002)
Blood
100, 2753-2762
| Abstract »
| Full Text »
| PDF »
- The Myogenic Basic Helix-Loop-Helix Family of Transcription Factors Shows Similar Requirements for SWI/SNF Chromatin Remodeling Enzymes during Muscle Differentiation in Culture.
- K. Roy, I. L. de la Serna, and A. N. Imbalzano (2002)
J. Biol. Chem.
277, 33818-33824
| Abstract »
| Full Text »
| PDF »
- Identification of Novel MyoD Gene Targets in Proliferating Myogenic Stem Cells.
- J. C. Wyzykowski, T. I. Winata, N. Mitin, E. J. Taparowsky, and S. F. Konieczny (2002)
Mol. Cell. Biol.
22, 6199-6208
| Abstract »
| Full Text »
| PDF »
- Early Cycling-independent Changes to p27, Cyclin D2, and Cyclin D3 in Differentiating Mouse Embryonal Carcinoma Cells.
- H. Preclikova, V. Bryja, J. Pachernik, P. Krejci, P. Dvorak, and A. Hampl (2002)
Cell Growth Differ.
13, 421-430
| Abstract »
| Full Text »
| PDF »
- Gene expression changes during mouse skeletal myoblast differentiation revealed by transcriptional profiling.
- J. L. Moran, Y. Li, A. A. Hill, W. M. Mounts, and C. P. Miller (2002)
Physiol Genomics
10, 103-111
| Abstract »
| Full Text »
| PDF »
- Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.
- J.-B. Lazaro, P. J. Bailey, and A. B. Lassar (2002)
Genes & Dev.
16, 1792-1805
| Abstract »
| Full Text »
| PDF »
- Positive Feedback Regulation between Akt2 and MyoD during Muscle Differentiation. CLONING OF Akt2 PROMOTER.
- S. Kaneko, R. I. Feldman, L. Yu, Z. Wu, T. Gritsko, S. A. Shelley, S. V. Nicosia, T. Nobori, and J. Q. Cheng (2002)
J. Biol. Chem.
277, 23230-23235
| Abstract »
| Full Text »
| PDF »
- Growth arrest by the LKB1 tumor suppressor: induction of p21WAF1/CIP1.
- M. Tiainen, K. Vaahtomeri, A. Ylikorkala, and T. P. Makela (2002)
Hum. Mol. Genet.
11, 1497-1504
| Abstract »
| Full Text »
| PDF »
- The Role of the Cyclin-dependent Kinase Inhibitor p21 in Apoptosis.
- A. L. Gartel and A. L. Tyner (2002)
Mol. Cancer Ther.
1, 639-649
| Abstract »
| Full Text »
| PDF »
- The MyoD-Inducible p204 Protein Overcomes the Inhibition of Myoblast Differentiation by Id Proteins.
- C.-j. Liu, B. Ding, H. Wang, and P. Lengyel (2002)
Mol. Cell. Biol.
22, 2893-2905
| Abstract »
| Full Text »
| PDF »
- Differential Effects of p21WAF1/CIP1 Deficiency on MMTV-ras and MMTV-myc Mammary Tumor Properties.
- D. J. Bearss, R. J. Lee, D. A. Troyer, R. G. Pestell, and J. J. Windle (2002)
Cancer Res.
62, 2077-2084
| Abstract »
| Full Text »
| PDF »
- Alternative Fates of Keratinocytes Transduced by Human Papillomavirus Type 18 E7 during Squamous Differentiation.
- W.-M. Chien, F. Noya, H. M. Benedict-Hamilton, T. R. Broker, and L. T. Chow (2002)
J. Virol.
76, 2964-2972
| Abstract »
| Full Text »
| PDF »
- Contribution of the Helix-Loop-Helix Factor Id2 to Regulation of Vascular Smooth Muscle Cell Proliferation.
- M. E. Matsumura, D. R. Lobe, and C. A. McNamara (2002)
J. Biol. Chem.
277, 7293-7297
| Abstract »
| Full Text »
| PDF »
- Tristetraprolin and LPS-inducible CXC chemokine are rapidly induced in presumptive satellite cells in response to skeletal muscle injury.
- C. Sachidanandan, R. Sambasivan, and J. Dhawan (2002)
J. Cell Sci.
115, 2701-2712
| Abstract »
| Full Text »
| PDF »
- Cell Cycle Signaling and Cardiovascular Disease.
- E.G. NABEL, M. BOEHM, L.M. AKYUREK, T. YOSHIMOTO, M.F. CROOK, M. OLIVE, H. SAN, and X. QU (2002)
Cold Spring Harb Symp Quant Biol
67, 163-170
| Abstract »
| PDF »
- Finding Genes in the C2C12 Osteogenic Pathway by k-Nearest-Neighbor Classification of Expression Data.
- J. Theilhaber, T. Connolly, S. Roman-Roman, S. Bushnell, A. Jackson, K. Call, T. Garcia, and R. Baron (2002)
Genome Res.
12, 165-176
| Abstract »
| Full Text »
| PDF »
- Human T-Cell Leukemia Virus Type 1 Tax Protein Inhibits the Expression of the Basic Helix-Loop-Helix Transcription Factor MyoD in Muscle Cells: Maintenance of Proliferation and Repression of Differentiation.
- P. Riou, M. Vandromme, and L. Gazzolo (2001)
Cell Growth Differ.
12, 613-622
| Abstract »
| Full Text »
| PDF »
- Role of p21Cip1/Waf1 in cell-cycle exit of endomitotic megakaryocytes.
- V. Baccini, L. Roy, N. Vitrat, H. Chagraoui, S. Sabri, J.-P. L. Couedic, N. Debili, F. Wendling, and W. Vainchenker (2001)
Blood
98, 3274-3282
| Abstract »
| Full Text »
| PDF »
- Common Regulation of Growth Arrest and Differentiation of Osteoblasts by Helix-Loop-Helix Factors.
- N. Funato, K. Ohtani, K. Ohyama, T. Kuroda, and M. Nakamura (2001)
Mol. Cell. Biol.
21, 7416-7428
| Abstract »
| Full Text »
| PDF »
- Up-Regulation of p27Kip1 by Progestins Is Involved in the Growth Suppression of the Normal and Malignant Human Endometrial Glandular Cells.
- T. Shiozawa, A. Horiuchi, K. Kato, M. Obinata, I. Konishi, S. Fujii, and T. Nikaido (2001)
Endocrinology
142, 4182-4188
| Abstract »
| Full Text »
| PDF »
- Tumor Susceptibility of p21Waf1/Cip1-deficient Mice.
- J. Martin-Caballero, J. M. Flores, P. Garcia-Palencia, and M. Serrano (2001)
Cancer Res.
61, 6234-6238
| Abstract »
| Full Text »
| PDF »
- p21cip1 Degradation in Differentiated Keratinocytes Is Abrogated by Costabilization with Cyclin E Induced by Human Papillomavirus E7.
- F. Noya, W.-M. Chien, T. R. Broker, and L. T. Chow (2001)
J. Virol.
75, 6121-6134
| Abstract »
| Full Text »
| PDF »
- The third wave of myotome colonization by mitotically competent progenitors: regulating the balance between differentiation and proliferation during muscle development.
- N. Kahane, Y. Cinnamon, I. Bachelet, and C. Kalcheim (2001)
Development
128, 2187-2198
| Abstract »
| Full Text »
| PDF »
- Role of the Increase in p21 in Cisplatin-Induced Acute Renal Failure in Rats.
- T. MIYAJI, A. KATO, H. YASUDA, Y. FUJIGAKI, and A. HISHIDA (2001)
J. Am. Soc. Nephrol.
12, 900-908
| Abstract »
| Full Text »
- 'Mitotic drive' of expanded CTG repeats in myotonic dystrophy type 1 (DM1).
- M. Khajavi, A. M. Tari, N. B. Patel, K. Tsuji, D. R. Siwak, M. L. Meistrich, N. H. A. Terry, and T. Ashizawa (2001)
Hum. Mol. Genet.
10, 855-863
| Abstract »
| Full Text »
| PDF »
- MyoD and Myogenin Expression Patterns in Cultures of Fetal and Adult Chicken Myoblasts.
- Z. YablonkaReuveni and B. M. Paterson (2001)
J. Histochem. Cytochem.
49, 455-462
| Abstract »
| Full Text »
- Coordinated Regulation of Rap1 and Thyroid Differentiation by Cyclic AMP and Protein Kinase A.
- O. M. Tsygankova, A. Saavedra, J. F. Rebhun, L. A. Quilliam, and J. L. Meinkoth (2001)
Mol. Cell. Biol.
21, 1921-1929
| Abstract »
| Full Text »
- Recruitment of (&bgr;)-catenin to cadherin-mediated intercellular adhesions is involved in myogenic induction.
- P Goichberg, M Shtutman, A Ben-Ze'ev, and B Geiger (2001)
J. Cell Sci.
114, 1309-1319
| Abstract »
| PDF »
- Alpha-skeletal actin induces a subset of muscle genes independently of muscle differentiation and withdrawal from the cell cycle.
- P. Gunning, V Ferguson, K. Brennan, and E. Hardeman (2001)
J. Cell Sci.
114, 513-524
| Abstract »
| PDF »
- p53 Regulates Myogenesis by Triggering the Differentiation Activity of pRb.
- A. Porrello, M. A. Cerone, S. Coen, A. Gurtner, G. Fontemaggi, L. Cimino, G. Piaggio, A. Sacchi, and S. Soddu (2000)
J. Cell Biol.
151, 1295-1304
| Abstract »
| Full Text »
| PDF »
- Coordinate Control of Muscle Cell Survival by Distinct Insulin-like Growth Factor Activated Signaling Pathways.
- M. A. Lawlor and P. Rotwein (2000)
J. Cell Biol.
151, 1131-1140
| Abstract »
| Full Text »
| PDF »
- Insulin-Like Growth Factor-Mediated Muscle Cell Survival: Central Roles for Akt and Cyclin-Dependent Kinase Inhibitor p21.
- M. A. Lawlor and P. Rotwein (2000)
Mol. Cell. Biol.
20, 8983-8995
| Abstract »
| Full Text »
|
|