Science 13 January 1995: Vol. 267. no. 5195, pp. 243 - 246 DOI: 10.1126/science.7809629

Prev | Table of Contents | Next

Articles

Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation.

R. Belizaire and E. R. Unanue (2009)
PNAS 106, 17463-17468
 |  Abstract »  |  Full Text »  |  PDF »

The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells.

L. Zou, J. Zhou, J. Zhang, J. Li, N. Liu, L. Chai, N. Li, T. Liu, L. Li, Z. Xie, et al. (2009)
PNAS 106, 15801-15806
 |  Abstract »  |  Full Text »  |  PDF »

Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy.

K. E. Broaders, J. A. Cohen, T. T. Beaudette, E. M. Bachelder, and J. M. J. Frechet (2009)
PNAS 106, 5497-5502
 |  Abstract »  |  Full Text »  |  PDF »

Receptor-mediated phagocytosis elicits cross-presentation in nonprofessional antigen-presenting cells.

A. Giodini, C. Rahner, and P. Cresswell (2009)
PNAS 106, 3324-3329
 |  Abstract »  |  Full Text »  |  PDF »

ISCOMATRIX Adjuvant Induces Efficient Cross-Presentation of Tumor Antigen by Dendritic Cells via Rapid Cytosolic Antigen Delivery and Processing via Tripeptidyl Peptidase II.

M. Schnurr, M. Orban, N. C. Robson, A. Shin, H. Braley, D. Airey, J. Cebon, E. Maraskovsky, and S. Endres (2009)
J. Immunol. 182, 1253-1259
 |  Abstract »  |  Full Text »  |  PDF »

Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation.

J. Mouries, G. Moron, G. Schlecht, N. Escriou, G. Dadaglio, and C. Leclerc (2008)
Blood 112, 3713-3722
 |  Abstract »  |  Full Text »  |  PDF »

Antigen Release Kinetics in the Phagosome Are Critical to Cross-Presentation Efficiency.

S. W. Howland and K. D. Wittrup (2008)
J. Immunol. 180, 1576-1583
 |  Abstract »  |  Full Text »  |  PDF »

Activation Outcomes Induced in Naive CD8 T-Cells by Macrophages Primed via "Phagocytic" and Nonphagocytic Pathways.

I. M. Olazabal, N. B. Martin-Cofreces, M. Mittelbrunn, G. Martinez del Hoyo, B. Alarcon, and F. Sanchez-Madrid (2008)
Mol. Biol. Cell 19, 701-710
 |  Abstract »  |  Full Text »  |  PDF »

N-Terminal Trimer Extension of Nominal CD8 T Cell Epitopes Is Sufficient to Promote Cross-Presentation to Cognate CD8 T Cells In Vivo.

C.-H. Wei and L. A. Sherman (2007)
J. Immunol. 179, 8280-8286
 |  Abstract »  |  Full Text »  |  PDF »

Neutrophils efficiently cross-prime naive T cells in vivo.

C. Beauvillain, Y. Delneste, M. Scotet, A. Peres, H. Gascan, P. Guermonprez, V. Barnaba, and P. Jeannin (2007)
Blood 110, 2965-2973
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Phagosome Maturation by Mycobacteria Does Not Interfere with Presentation of Mycobacterial Antigens by MHC Molecules.

L. Majlessi, B. Combaluzier, I. Albrecht, J. E. Garcia, C. Nouze, J. Pieters, and C. Leclerc (2007)
J. Immunol. 179, 1825-1833
 |  Abstract »  |  Full Text »  |  PDF »

A Transporter Associated with Antigen-Processing Independent Vacuolar Pathway for the MHC Class I-Mediated Presentation of Endogenous Transmembrane Proteins.

N. Tiwari, N. Garbi, T. Reinheckel, G. Moldenhauer, G. J. Hammerling, and F. Momburg (2007)
J. Immunol. 178, 7932-7942
 |  Abstract »  |  Full Text »  |  PDF »

Use of Native Lactococci as Vehicles for Delivery of DNA into Mammalian Epithelial Cells.

V. D. Guimaraes, S. Innocentin, F. Lefevre, V. Azevedo, J.-M. Wal, P. Langella, and J.-M. Chatel (2006)
Appl. Envir. Microbiol. 72, 7091-7097
 |  Abstract »  |  Full Text »  |  PDF »

Leishmania Antigens Are Presented to CD8+ T Cells by a Transporter Associated with Antigen Processing-Independent Pathway In Vitro and In Vivo.

S. Bertholet, R. Goldszmid, A. Morrot, A. Debrabant, F. Afrin, C. Collazo-Custodio, M. Houde, M. Desjardins, A. Sher, and D. Sacks (2006)
J. Immunol. 177, 3525-3533
 |  Abstract »  |  Full Text »  |  PDF »

Role of Immunoproteasomes in Cross-Presentation.

M. J. Palmowski, U. Gileadi, M. Salio, A. Gallimore, M. Millrain, E. James, C. Addey, D. Scott, J. Dyson, E. Simpson, et al. (2006)
J. Immunol. 177, 983-990
 |  Abstract »  |  Full Text »  |  PDF »

Secreted Proteins from Mycobacterium tuberculosis Gain Access to the Cytosolic MHC Class-I Antigen-Processing Pathway.

D. M. Lewinsohn, J. E. Grotzke, A. S. Heinzel, L. Zhu, P. J. Ovendale, M. Johnson, and M. R. Alderson (2006)
J. Immunol. 177, 437-442
 |  Abstract »  |  Full Text »  |  PDF »

Essential role for cholesterol in the delivery of exogenous antigens to the MHC class I-presentation pathway.

I. Albrecht, J. Gatfield, T. Mini, P. Jeno, and J. Pieters (2006)
Int. Immunol. 18, 755-765
 |  Abstract »  |  Full Text »  |  PDF »

Identification of the Immunodominant HY H2-Dk Epitope and Evaluation of the Role of Direct and Indirect Antigen Presentation in HY Responses.

M. Millrain, D. Scott, C. Addey, H. Dewchand, P. Ellis, I. Ehrmann, M. Mitchell, P. Burgoyne, E. Simpson, and J. Dyson (2005)
J. Immunol. 175, 7209-7217
 |  Abstract »  |  Full Text »  |  PDF »

Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo.

D. Accapezzato, V. Visco, V. Francavilla, C. Molette, T. Donato, M. Paroli, M. U. Mondelli, M. Doria, M. R. Torrisi, and V. Barnaba (2005)
J. Exp. Med. 202, 817-828
 |  Abstract »  |  Full Text »  |  PDF »

Enhancement of Dendritic Cell Antigen Cross-Presentation by CpG DNA Involves Type I IFN and Stabilization of Class I MHC mRNA.

J. Kuchtey, P. J. Chefalo, R. C. Gray, L. Ramachandra, and C. V. Harding (2005)
J. Immunol. 175, 2244-2251
 |  Abstract »  |  Full Text »  |  PDF »

Immunization With Mutant p53- and K-ras-Derived Peptides in Cancer Patients: Immune Response and Clinical Outcome.

D. P. Carbone, I. F. Ciernik, M. J. Kelley, M. C. Smith, S. Nadaf, D. Kavanaugh, V. E. Maher, M. Stipanov, D. Contois, B. E. Johnson, et al. (2005)
J. Clin. Oncol. 23, 5099-5107
 |  Abstract »  |  Full Text »  |  PDF »

Virus-Specific CD4+ and CD8+ Cytotoxic T-Cell Responses and Long-Term T-Cell Memory in Individuals Vaccinated against Polio.

R. Wahid, M. J. Cannon, and M. Chow (2005)
J. Virol. 79, 5988-5995
 |  Abstract »  |  Full Text »  |  PDF »

Matrix Metalloproteinase Activity and Osteoclasts in Experimental Prostate Cancer Bone Metastasis Tissue.

Z. Dong, R. D. Bonfil, S. Chinni, X. Deng, J. C. Trindade Filho, M. Bernardo, U. Vaishampayan, M. Che, B. F. Sloane, S. Sheng, et al. (2005)
Am. J. Pathol. 166, 1173-1186
 |  Abstract »  |  Full Text »  |  PDF »

Cross-Priming of T Cell Responses by Synthetic Microspheres Carrying a CD8+ T Cell Epitope Requires an Adjuvant Signal.

F. Boisgerault, P. Rueda, C. M. Sun, S. Hervas-Stubbs, M. Rojas, and C. Leclerc (2005)
J. Immunol. 174, 3432-3439
 |  Abstract »  |  Full Text »  |  PDF »

Immunization with Lentiviral Vector-Transduced Dendritic Cells Induces Strong and Long-Lasting T Cell Responses and Therapeutic Immunity.

Y. He, J. Zhang, Z. Mi, P. Robbins, and L. D. Falo Jr (2005)
J. Immunol. 174, 3808-3817
 |  Abstract »  |  Full Text »  |  PDF »

Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery.

M. Schnurr, Q. Chen, A. Shin, W. Chen, T. Toy, C. Jenderek, S. Green, L. Miloradovic, D. Drane, I. D. Davis, et al. (2005)
Blood 105, 2465-2472
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Intracellular Routes in the Cross-Presentation of a Soluble Protein by Murine Dendritic Cells.

D. Palliser, E. Guillen, M. Ju, and H. N. Eisen (2005)
J. Immunol. 174, 1879-1887
 |  Abstract »  |  Full Text »  |  PDF »

Cross-Presentation of Listeria-Derived CD8 T Cell Epitopes Requires Unstable Bacterial Translation Products.

J. Janda, P. Schoneberger, M. Skoberne, M. Messerle, H. Russmann, and G. Geginat (2004)
J. Immunol. 173, 5644-5651
 |  Abstract »  |  Full Text »  |  PDF »

pH-Triggered Microparticles for Peptide Vaccination.

W. N. Haining, D. G. Anderson, S. R. Little, M. S. von Berwelt-Baildon, A. A. Cardoso, P. Alves, K. Kosmatopoulos, L. M. Nadler, R. Langer, and D. S. Kohane (2004)
J. Immunol. 173, 2578-2585
 |  Abstract »  |  Full Text »  |  PDF »

Mesothelin-specific CD8+ T Cell Responses Provide Evidence of In Vivo Cross-Priming by Antigen-Presenting Cells in Vaccinated Pancreatic Cancer Patients.

A. M. Thomas, L. M. Santarsiero, E. R. Lutz, T. D. Armstrong, Y.-C. Chen, L.-Q. Huang, D. A. Laheru, M. Goggins, R. H. Hruban, and E. M. Jaffee (2004)
J. Exp. Med. 200, 297-306
 |  Abstract »  |  Full Text »  |  PDF »

Antigen Transport and Cytoskeletal Characteristics of a Distinct Enterocyte Population in Inflammatory Bowel Diseases.

S. Kersting, M. Bruewer, G. Schuermann, A. Klotz, M. Utech, M. Hansmerten, C. F. Krieglstein, N. Senninger, J.-D. Schulzke, H. Y. Naim, et al. (2004)
Am. J. Pathol. 165, 425-437
 |  Abstract »  |  Full Text »  |  PDF »

Heat Shock Protein-Mediated Cross-Presentation of Exogenous HIV Antigen on HLA Class I and Class II.

D. SenGupta, P. J. Norris, T. J. Suscovich, M. Hassan-Zahraee, H. F. Moffett, A. Trocha, R. Draenert, P. J. R. Goulder, R. J. Binder, D. L. Levey, et al. (2004)
J. Immunol. 173, 1987-1993
 |  Abstract »  |  Full Text »  |  PDF »

Neutrophil Involvement in Cross-Priming CD8+ T Cell Responses to Bacterial Antigens.

A. R. Tvinnereim, S. E. Hamilton, and J. T. Harty (2004)
J. Immunol. 173, 1994-2002
 |  Abstract »  |  Full Text »  |  PDF »

Phosphatidylserine Receptor-Mediated Recognition of Archaeosome Adjuvant Promotes Endocytosis and MHC Class I Cross-Presentation of the Entrapped Antigen by Phagosome-to-Cytosol Transport and Classical Processing.

K. Gurnani, J. Kennedy, S. Sad, G. D. Sprott, and L. Krishnan (2004)
J. Immunol. 173, 566-578
 |  Abstract »  |  Full Text »  |  PDF »

Loading of MHC Class I and II Presentation Pathways by Exogenous Antigens: A Quantitative In Vivo Comparison.

T. Storni and M. F. Bachmann (2004)
J. Immunol. 172, 6129-6135
 |  Abstract »  |  Full Text »  |  PDF »

Bacterial and Host Factors Involved in the Major Histocompatibility Complex Class Ib-Restricted Presentation of Salmonella Hsp 60: Novel Pathway.

W.-F. Lo, C. D. Dunn, H. Ong, E. S. Metcalf, and M. J. Soloski (2004)
Infect. Immun. 72, 2843-2849
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells.

J. F. Fonteneau, D. G. Kavanagh, M. Lirvall, C. Sanders, T. L. Cover, N. Bhardwaj, and M. Larsson (2003)
Blood 102, 4448-4455
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Efficient MHC Class I Cross-Presentation during Early Vaccinia Infection Requires the Transfer of Proteasomal Intermediates between Antigen Donor and Presenting Cells.

A. Serna, M. C. Ramirez, A. Soukhanova, and L. J. Sigal (2003)
J. Immunol. 171, 5668-5672
 |  Abstract »  |  Full Text »  |  PDF »

Endogenous neosynthesis vs. cross-presentation of viral antigens for cytotoxic T cell priming.

S. Freigang, D. Egger, K. Bienz, H. Hengartner, and R. M. Zinkernagel (2003)
PNAS 100, 13477-13482
 |  Abstract »  |  Full Text »  |  PDF »

Fbs2 Is a New Member of the E3 Ubiquitin Ligase Family That Recognizes Sugar Chains.

Y. Yoshida, F. Tokunaga, T. Chiba, K. Iwai, K. Tanaka, and T. Tai (2003)
J. Biol. Chem. 278, 43877-43884
 |  Abstract »  |  Full Text »  |  PDF »

Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens.

A. L. Ackerman, C. Kyritsis, R. Tampe, and P. Cresswell (2003)
PNAS 100, 12889-12894
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo, Dendritic Cells Can Cross-Present Virus-Like Particles Using an Endosome-to-Cytosol Pathway.

V. G. Moron, P. Rueda, C. Sedlik, and C. Leclerc (2003)
J. Immunol. 171, 2242-2250
 |  Abstract »  |  Full Text »  |  PDF »

Tapasin-/- and TAP1-/- Macrophages Are Deficient in Vacuolar Alternate Class I MHC (MHC-I) Processing due to Decreased MHC-I Stability at Phagolysosomal pH.

P. J. Chefalo, A. G. Grandea III, L. Van Kaer, and C. V. Harding (2003)
J. Immunol. 170, 5825-5833
 |  Abstract »  |  Full Text »  |  PDF »

Cross-Presentation of HLA Class I Epitopes from Exogenous NY-ESO-1 Polypeptides by Nonprofessional APCs.

S. Gnjatic, D. Atanackovic, M. Matsuo, E. Jager, S. Y. Lee, D. Valmori, Y.-T. Chen, G. Ritter, A. Knuth, and L. J. Old (2003)
J. Immunol. 170, 1191-1196
 |  Abstract »  |  Full Text »  |  PDF »

Macrophages and Dendritic Cells Use the Cytosolic Pathway to Rapidly Cross-Present Antigen from Live, Vaccinia-Infected Cells.

M. C. Ramirez and L. J. Sigal (2002)
J. Immunol. 169, 6733-6742
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Specific Immune Responses by Polycation-Based Vaccines.

P. Luhrs, W. Schmidt, R. Kutil, M. Buschle, S. N. Wagner, G. Stingl, and A. Schneeberger (2002)
J. Immunol. 169, 5217-5226
 |  Abstract »  |  Full Text »  |  PDF »

Direct Priming and Cross-Priming Contribute Differentially to the Induction of CD8+ CTL Following Exposure to Vaccinia Virus Via Different Routes.

X. Shen, S. B. J. Wong, C. B. Buck, J. Zhang, and R. F. Siliciano (2002)
J. Immunol. 169, 4222-4229
 |  Abstract »  |  Full Text »  |  PDF »

Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations.

Y. Nagata, S. Ono, M. Matsuo, S. Gnjatic, D. Valmori, G. Ritter, W. Garrett, L. J. Old, and I. Mellman (2002)
PNAS 99, 10629-10634
 |  Abstract »  |  Full Text »  |  PDF »

Cross-Presentation of Listeria monocytogenes-Derived CD4 T Cell Epitopes.

M. Skoberne, S. Schenk, H. Hof, and G. Geginat (2002)
J. Immunol. 169, 1410-1418
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{alpha}{beta} Promote Priming of Antigen-Specific CD8+ and CD4+ T Lymphocytes by Immunostimulatory DNA-Based Vaccines.

H. J. Cho, T. Hayashi, S. K. Datta, K. Takabayashi, J. H. Van Uden, A. Horner, M. Corr, and E. Raz (2002)
J. Immunol. 168, 4907-4913
 |  Abstract »  |  Full Text »  |  PDF »

Presentation of a major histocompatibility complex class 1-binding peptide by monocyte-derived dendritic cells incorporating hydrophobized polysaccharide-truncated HER2 protein complex: implications for a polyvalent immuno-cell therapy.

Y. Ikuta, N. Katayama, L. Wang, T. Okugawa, Y. Takahashi, M. Schmitt, X. Gu, M. Watanabe, K. Akiyoshi, H. Nakamura, et al. (2002)
Blood 99, 3717-3724
 |  Abstract »  |  Full Text »  |  PDF »

Critical Role for Activation of Antigen-Presenting Cells in Priming of Cytotoxic T Cell Responses After Vaccination with Virus-Like Particles.

T. Storni, F. Lechner, I. Erdmann, T. Bachi, A. Jegerlehner, T. Dumrese, T. M. Kundig, C. Ruedl, and M. F. Bachmann (2002)
J. Immunol. 168, 2880-2886
 |  Abstract »  |  Full Text »  |  PDF »

Cellular Processing of a Multibranched Lysine Core with Tumor Antigen Peptides and Presentation of Peptide Epitopes Recognized by Cytotoxic T Lymphocytes on Antigen-presenting Cells.

S. Ota, T. Ono, A. Morita, A. Uenaka, M. Harada, and E. Nakayama (2002)
Cancer Res. 62, 1471-1476
 |  Abstract »  |  Full Text »  |  PDF »

Identification of HLA-A2-restricted CD8+ Cytotoxic T Cell Responses in Primary Biliary Cirrhosis: T Cell Activation Is Augmented by Immune Complexes Cross-Presented by Dendritic Cells.

H. Kita, Z.-X. Lian, J. Van de Water, X.-S. He, S. Matsumura, M. Kaplan, V. Luketic, R. L. Coppel, A. A. Ansari, and M. E. Gershwin (2002)
J. Exp. Med. 195, 113-123
 |  Abstract »  |  Full Text »  |  PDF »

CD8 T Cells Inhibit IgE Via Dendritic Cell IL-12 Induction That Promotes Th1 T Cell Counter-Regulation.

M. J. Thomas, A. Noble, E. Sawicka, P. W. Askenase, and D. M. Kemeny (2002)
J. Immunol. 168, 216-223
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Immunity in Peripheral Tissues Combined with Intracerebral Transplantation of Interleukin-2-producing Cells Eliminates Established Brain Tumors.

Y. Iwadate, A. Yamaura, Y. Sato, S. Sakiyama, and M. Tagawa (2001)
Cancer Res. 61, 8769-8774
 |  Abstract »  |  Full Text »  |  PDF »

CD40 Cross-Linking Bypasses the Absolute Requirement for CD4 T Cells during Immunization with Melanoma Antigen Gene-modified Dendritic Cells.

A. Ribas, L. H. Butterfield, S. N. Amarnani, V. B. Dissette, D. Kim, W. S. Meng, G. A. Miranda, H.-J. Wang, W. H. McBride, J. A. Glaspy, et al. (2001)
Cancer Res. 61, 8787-8793
 |  Abstract »  |  Full Text »  |  PDF »

Generation of cytotoxic T lymphocytes by MHC class I ligands fused to heat shock cognate protein 70.

H. Udono, T. Yamano, Y. Kawabata, M. Ueda, and K. Yui (2001)
Int. Immunol. 13, 1233-1242
 |  Abstract »  |  Full Text »  |  PDF »

Neutrophils Process Exogenous Bacteria Via an Alternate Class I MHC Processing Pathway for Presentation of Peptides to T Lymphocytes.

N. S. Potter and C. V. Harding (2001)
J. Immunol. 167, 2538-2546
 |  Abstract »  |  Full Text »  |  PDF »

Stress-Induced ClpP Serine Protease of Listeria monocytogenes Is Essential for Induction of Listeriolysin O-Dependent Protective Immunity.

O. Gaillot, S. Bregenholt, F. Jaubert, J. P. Di Santo, and P. Berche (2001)
Infect. Immun. 69, 4938-4943
 |  Abstract »  |  Full Text »  |  PDF »

Processing of Exogenous Antigens for Presentation by Class I MHC Molecules Involves Post-Golgi Peptide Exchange Influenced by Peptide-MHC Complex Stability and Acidic pH.

P. J. Chefalo and C. V. Harding (2001)
J. Immunol. 167, 1274-1282
 |  Abstract »  |  Full Text »  |  PDF »

Protection Against Murine Listeriosis by Oral Vaccination with Recombinant Salmonella Expressing Hybrid Yersinia Type III Proteins.

H. Russmann, E. I. Igwe, J. Sauer, W.-D. Hardt, A. Bubert, and G. Geginat (2001)
J. Immunol. 167, 357-365
 |  Abstract »  |  Full Text »  |  PDF »

Factors Affecting the Efficiency of CD8+ T Cell Cross-Priming with Exogenous Antigens.

H. T. Maecker, S. A. Ghanekar, M. A. Suni, X.-S. He, L. J. Picker, and V. C. Maino (2001)
J. Immunol. 166, 7268-7275
 |  Abstract »  |  Full Text »  |  PDF »

Targeting Dendritic Cells to Enhance DNA Vaccine Potency.

Z. You, X. Huang, J. Hester, H. C. Toh, and S.-Y. Chen (2001)
Cancer Res. 61, 3704-3711
 |  Abstract »  |  Full Text »

Human Cytomegalovirus pp65- and Immediate Early 1 Antigen-Specific HLA Class I-Restricted Cytotoxic T Cell Responses Induced by Cross-Presentation of Viral Antigens.

Z. Tabi, M. Moutaftsi, and L. K. Borysiewicz (2001)
J. Immunol. 166, 5695-5703
 |  Abstract »  |  Full Text »  |  PDF »

The Roles of MHC Class II, CD40, and B7 Costimulation in CTL Induction by Plasmid DNA.

K. Chan, D. J. Lee, A. Schubert, C. M. Tang, B. Crain, S. P. Schoenberger, and M. Corr (2001)
J. Immunol. 166, 3061-3066
 |  Abstract »  |  Full Text »  |  PDF »

A Retrogen Strategy for Presentation of an Intracellular Tumor Antigen as an Exogenous Antigen by Dendritic Cells Induces Potent Antitumor T Helper and CTL Responses.

Z. You, J. Hester, L. Rollins, G. C. Spagnoli, P. van der Bruggen, and S.-Y. Chen (2001)
Cancer Res. 61, 197-205
 |  Abstract »  |  Full Text »

Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells.

P. Brossart, S. Wirths, G. Stuhler, V. L. Reichardt, L. Kanz, and W. Brugger (2000)
Blood 96, 3102-3108
 |  Abstract »  |  Full Text »  |  PDF »

Bone Marrow-Derived Antigen-Presenting Cells Are Required for the Generation of Cytotoxic T Lymphocyte Responses to Viruses and Use Transporter Associated with Antigen Presentation (Tap)-Dependent and -Independent Pathways of Antigen Presentation.

L. J. Sigal and K. L. Rock (2000)
J. Exp. Med. 192, 1143-1150
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Vigorous Helper and Cytotoxic T Cell as well as B Cell Responses by Dendritic Cells Expressing a Modified Antigen Targeting Receptor-Mediated Internalization Pathway.

Z. You, X. F. Huang, J. Hester, L. Rollins, C. Rooney, and S.-Y. Chen (2000)
J. Immunol. 165, 4581-4591
 |  Abstract »  |  Full Text »  |  PDF »

The B Subunit of Shiga Toxin Fused to a Tumor Antigen Elicits CTL and Targets Dendritic Cells to Allow MHC Class I-Restricted Presentation of Peptides Derived from Exogenous Antigens.

N. Haicheur, E. Bismuth, S. Bosset, O. Adotevi, G. Warnier, V. Lacabanne, A. Regnault, C. Desaymard, S. Amigorena, P. Ricciardi-Castagnoli, et al. (2000)
J. Immunol. 165, 3301-3308
 |  Abstract »  |  Full Text »  |  PDF »

Antigen-Presenting Cells in the Female Reproductive Tract: Influence of Estradiol on Antigen Presentation by Vaginal Cells.

C. R. Wira, R. M. Rossoll, and C. Kaushic (2000)
Endocrinology 141, 2877-2885
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Induction of a High-Avidity, High-Frequency Cytotoxic T-Lymphocyte Response Is Associated with Antiviral Protective Immunity.

C. Sedlik, G. Dadaglio, M. F. Saron, E. Deriaud, M. Rojas, S. I. Casal, and C. Leclerc (2000)
J. Virol. 74, 5769-5775
 |  Abstract »  |  Full Text »

CD8+ CTL from Lungs of Mycobacterium tuberculosis-Infected Mice Express Perforin In Vivo and Lyse Infected Macrophages.

N. V. Serbina, C.-C. Liu, C. A. Scanga, and J. L. Flynn (2000)
J. Immunol. 165, 353-363
 |  Abstract »  |  Full Text »  |  PDF »

Receptor-Mediated Uptake of Antigen/Heat Shock Protein Complexes Results in Major Histocompatibility Complex Class I Antigen Presentation via Two Distinct Processing Pathways.

F. Castellino, P. E. Boucher, K. Eichelberg, M. Mayhew, J. E. Rothman, A. N. Houghton, and R. N. Germain (2000)
J. Exp. Med. 191, 1957-1964
 |  Abstract »  |  Full Text »  |  PDF »

Sequential Cleavage by Metallopeptidases and Proteasomes Is Involved in Processing HIV-1 ENV Epitope for Endogenous MHC Class I Antigen Presentation.

D. Lopez, B. C. Gil-Torregrosa, C. Bergmann, and M. Del Val (2000)
J. Immunol. 164, 5070-5077
 |  Abstract »  |  Full Text »  |  PDF »

CD8+ T-Cell Priming against a Nonsecreted Listeria monocytogenes Antigen Is Independent of the Antimicrobial Activities of Gamma Interferon.

A. R. Tvinnereim and J. T. Harty (2000)
Infect. Immun. 68, 2196-2204
 |  Abstract »  |  Full Text »  |  PDF »

Preclinical Evaluation of "Whole" Cell Vaccines for Prophylaxis and Therapy Using a Disabled Infectious Single Cycle-Herpes Simplex Virus Vector to Transduce Cytokine Genes.

S. A. Ali, C. S. McLean, M. E. G. Boursnell, G. Martin, C. L. Holmes, S. Reeder, C. Entwisle, D. M. Blakeley, J. G. Shields, S. Todryk, et al. (2000)
Cancer Res. 60, 1663-1670
 |  Abstract »  |  Full Text »

Stimulation of cytotoxic T cells against idiotype immunoglobulin of malignant lymphoma with protein-pulsed or idiotype-transduced dendritic cells.

F. Osterroth, A. Garbe, P. Fisch, and H. Veelken (2000)
Blood 95, 1342-1349
 |  Abstract »  |  Full Text »  |  PDF »

Cd40-Independent Pathways of T Cell Help for Priming of Cd8+ Cytotoxic T Lymphocytes.

Z. Lu, L. Yuan, X. Zhou, E. Sotomayor, H. I. Levitsky, and D. M. Pardoll (2000)
J. Exp. Med. 191, 541-550
 |  Abstract »  |  Full Text »  |  PDF »

Bacterial Proteins Can Be Processed by Macrophages in a Transporter Associated with Antigen Processing-Independent, Cysteine Protease-Dependent Manner for Presentation by MHC Class I Molecules.

D. J. Campbell, T. Serwold, and N. Shastri (2000)
J. Immunol. 164, 168-175
 |  Abstract »  |  Full Text »  |  PDF »

Mycobacterial infection of macrophages results in membrane-permeable phagosomes.

R. Teitelbaum, M. Cammer, M. L. Maitland, N. E. Freitag, J. Condeelis, and B. R. Bloom (1999)
PNAS 96, 15190-15195
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Priming by DNA Injection Occurs Predominantly by Antigen Transfer.

M. Corr, A. von Damm, D. J. Lee, and H. Tighe (1999)
J. Immunol. 163, 4721-4727
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency of Transporter for Antigen Presentation (TAP) in Tumor Cells Allows Evasion of Immune Surveillance and Increases Tumorigenesis.

A. K. Johnsen, D. J. Templeton, M.-S. Sy, and C. V. Harding (1999)
J. Immunol. 163, 4224-4231
 |  Abstract »  |  Full Text »  |  PDF »

Early Emergence of CD8+ T Cells Primed for Production of Type 1 Cytokines in the Lungs of Mycobacterium tuberculosis-Infected Mice.

N. V. Serbina and J. L. Flynn (1999)
Infect. Immun. 67, 3980-3988
 |  Abstract »  |  Full Text »  |  PDF »

Sialoadhesin-Positive Host Macrophages Play an Essential Role in Graft-Versus-Leukemia Reactivity in Mice.

S. Muerkoster, M. Rocha, P. R. Crocker, V. Schirrmacher, and V. Umansky (1999)
Blood 93, 4375-4386
 |  Abstract »  |  Full Text »  |  PDF »

Antigen Secreted from Noncytosolic Listeria monocytogenes Is Processed by the Classical MHC Class I Processing Pathway.

H. L. Zwickey and T. A. Potter (1999)
J. Immunol. 162, 6341-6350
 |  Abstract »  |  Full Text »  |  PDF »

Presentation of Tumor Antigens by Phagocytic Dendritic Cell Clusters Generated from Human CD34+ Hematopoietic Progenitor Cells: Induction of Autologous Cytotoxic T Lymphocytes against Leukemic Cells in Acute Myelogenous Leukemia Patients.

S.-i. Fujii, K. Fujimoto, K. Shimizu, T. Ezaki, F. Kawano, K. Takatsuki, M. Kawakita, and K. Matsuno (1999)
Cancer Res. 59, 2150-2158
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Responses to Gram-Negative Intracellular Bacterial Pathogens: A Role for CD8+ T Cells in Immunity to Salmonella Infection and the Involvement of MHC Class Ib Molecules.

W.-F. Lo, H. Ong, E. S. Metcalf, and M. J. Soloski (1999)
J. Immunol. 162, 5398-5406
 |  Abstract »  |  Full Text »  |  PDF »

Immune-Stimulating Complexes Induce an IL-12-Dependent Cascade of Innate Immune Responses.

R. E. Smith, A. M. Donachie, D. Grdic, N. Lycke, and A. McI. Mowat (1999)
J. Immunol. 162, 5536-5546
 |  Abstract »  |  Full Text »  |  PDF »

MHC Class I-Restricted Presentation of Maleylated Protein Binding to Scavenger Receptors.

P. Bansal, P. Mukherjee, S. K. Basu, A. George, V. Bal, and S. Rath (1999)
J. Immunol. 162, 4430-4437
 |  Abstract »  |  Full Text »  |  PDF »

Direct Delivery of the Bordetella pertussis Adenylate Cyclase Toxin to the MHC Class I Antigen Presentation Pathway.

P. Guermonprez, D. Ladant, G. Karimova, A. Ullmann, and C. Leclerc (1999)
J. Immunol. 162, 1910-1916
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Delivery of a Cytolytic T-Lymphocyte Epitope Peptide by Pertussis Toxin to Major Histocompatibility Complex Class I without Involvement of the Cytosolic Class I Antigen Processing Pathway.

N. H. Carbonetti, T. J. Irish, C. H. Chen, C. B. O'Connell, G. A. Hadley, U. McNamara, R. G. Tuskan, and G. K. Lewis (1999)
Infect. Immun. 67, 602-607
 |  Abstract »  |  Full Text »  |  PDF »

Colorectal Cancer as a Model for Immunotherapy.

K. A. Foon, J. Yannelli, and M. Bhattacharya-Chatterjee (1999)
Clin. Cancer Res. 5, 225-236
 |  Full Text »  |  PDF »

Fc{gamma} Receptor-mediated Induction of Dendritic Cell Maturation and Major Histocompatibility Complex Class I-restricted Antigen Presentation after Immune Complex Internalization.

A. Regnault, D. Lankar, V. Lacabanne, A. Rodriguez, C. Thery, M. Rescigno, T. Saito, S. Verbeek, C. Bonnerot, P. Ricciardi-Castagnoli, et al. (1999)
J. Exp. Med. 189, 371-380
 |  Abstract »  |  Full Text »  |  PDF »

Receptor mediated and fluid phase pathways for internalization of the ER Hsp90 chaperone GRP94 in murine macrophages.

J. Wassenberg, C Dezfulian, and C. Nicchitta (1999)
J. Cell Sci. 112, 2167-2175
 |  Abstract »  |  PDF »

Induction of Immunologic Tolerance for Transplantation.

A. A. ROSSINI, D. L. GREINER, and J. P. MORDES (1999)
Physiol Rev 79, 99-141
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Human CD8+ {alpha}{beta} TCR+ Cells by Mycobacterium tuberculosis Via an Alternate Class I MHC Antigen-Processing Pathway.

D. H. Canaday, C. Ziebold, E. H. Noss, K. A. Chervenak, C. V. Harding, and W. H. Boom (1999)
J. Immunol. 162, 372-379
 |  Abstract »  |  Full Text »  |  PDF »

Modulating the immune response to genetic immunization.

Adam. D. Cohen, J. D. Boyer, and D. B. Weiner (1998)
FASEB J 12, 1611-1626
 |  Abstract »  |  Full Text »

To Advertise   |   Find Products