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Science 16 December 1994:
Vol. 266. no. 5192, pp. 1865 - 1869
DOI: 10.1126/science.7997879

Articles

Science, Vol 266, Issue 5192, 1865-1869
Copyright © 1994 by American Association for the Advancement of Science


articles

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

Y Chang, E Cesarman, MS Pessin, F Lee, J Culpepper, DM Knowles, and PS Moore

Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.

Representational difference analysis was used to isolate unique sequences present in more than 90 percent of Kaposi's sarcoma (KS) tissues obtained from patients with acquired immunodeficiency syndrome (AIDS). These sequences were not present in tissue DNA from non-AIDS patients, but were present in 15 percent of non-KS tissue DNA samples from AIDS patients. The sequences are homologous to, but distinct from, capsid and tegument protein genes of the Gammaherpesvirinae, herpesvirus saimiri and Epstein-Barr virus. These KS-associated herpesvirus-like (KSHV) sequences appear to define a new human herpesvirus.


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S. Z. Gandy, S. D. Linnstaedt, S. Muralidhar, K. A. Cashman, L. J. Rosenthal, and J. L. Casey (2007)
J. Virol. 81, 13544-13551
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Phase 2 study of pegylated liposomal doxorubicin in combination with interleukin-12 for AIDS-related Kaposi sarcoma.
R. F. Little, K. Aleman, P. Kumar, K. M. Wyvill, J. M. Pluda, E. Read-Connole, V. Wang, S. Pittaluga, A. T. Catanzaro, S. M. Steinberg, et al. (2007)
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   Abstract »    Full Text »    PDF »
Kaposi's Sarcoma-Associated Herpesvirus Encodes an Ortholog of miR-155.
R. L. Skalsky, M. A. Samols, K. B. Plaisance, I. W. Boss, A. Riva, M. C. Lopez, H. V. Baker, and R. Renne (2007)
J. Virol. 81, 12836-12845
   Abstract »    Full Text »    PDF »
Kaposi sarcoma-associated herpesvirus/human herpesvirus 8 and lymphoproliferative disorders.
M-Q Du, C M Bacon, and P G Isaacson (2007)
J. Clin. Pathol. 60, 1350-1357
   Abstract »    Full Text »    PDF »
HIV infection and lymphoma.
K L Grogg, R F Miller, and A Dogan (2007)
J. Clin. Pathol. 60, 1365-1372
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Identification of the DNA Sequence Interacting with Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 1.
J. Park, M.-S. Lee, S.-M. Yoo, K. W. Jeong, D. Lee, J. Choe, and T. Seo (2007)
J. Virol. 81, 12680-12684
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Sarcoma.
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Binding of Kaposi's Sarcoma-Associated Herpesvirus K-bZIP to Interferon-Responsive Factor 3 Elements Modulates Antiviral Gene Expression.
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Kaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sel10 protein.
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M. C. B. Godoy, H. Rouse, J. A. Brown, P. Phillips, D. M. Forrest, and N. L. Muller (2007)
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D. A. Davis, K. E. Singer, I. P. Reynolds, M. Haque, and R. Yarchoan (2007)
Cancer Res. 67, 7003-7010
   Abstract »    Full Text »    PDF »
Kaposi's Sarcoma-Associated Herpesvirus Infection Promotes Invasion of Primary Human Umbilical Vein Endothelial Cells by Inducing Matrix Metalloproteinases.
L.-W. Qian, J. Xie, F. Ye, and S.-J. Gao (2007)
J. Virol. 81, 7001-7010
   Abstract »    Full Text »    PDF »
Familial blood vessel tumors and subsequent cancers.
J Ji and K Hemminki (2007)
Ann. Onc. 18, 1260-1267
   Abstract »    Full Text »    PDF »
AIDS-Related Cancer and Severity of Immunosuppression in Persons With AIDS.
R. J. Biggar, A. K. Chaturvedi, J. J. Goedert, and E. A. Engels (2007)
J Natl Cancer Inst 99, 962-972
   Abstract »    Full Text »    PDF »
The Transcriptional Repressor K-RBP Modulates RTA-Mediated Transactivation and Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus.
Z. Yang and C. Wood (2007)
J. Virol. 81, 6294-6306
   Abstract »    Full Text »    PDF »
Kaposi Sarcoma-associated Herpes Virus Targets the Lymphotactin Receptor with Both a Broad Spectrum Antagonist vCCL2 and a Highly Selective and Potent Agonist vCCL3.
H. R. Luttichau, A. H. Johnsen, J. Jurlander, M. M. Rosenkilde, and T. W. Schwartz (2007)
J. Biol. Chem. 282, 17794-17805
   Abstract »    Full Text »    PDF »
Functional characterization of the M-type K15-encoded membrane protein of Kaposi's sarcoma-associated herpesvirus.
L. Wang, M. M. Brinkmann, M. Pietrek, M. Ottinger, O. Dittrich-Breiholz, M. Kracht, and T. F. Schulz (2007)
J. Gen. Virol. 88, 1698-1707
   Abstract »    Full Text »    PDF »
Human herpes virus 8 infection in kidney transplant patients from an area of northwestern Italy (Piemonte region).
M. Bergallo, C. Costa, S. Margio, F. Sidoti, D. Re, G. P. Segoloni, and R. Cavallo (2007)
Nephrol. Dial. Transplant. 22, 1757-1761
   Abstract »    Full Text »    PDF »
Signaling Cascades Triggered by Bacterial Metabolic End Products during Reactivation of Kaposi's Sarcoma-Associated Herpesvirus.
T. L. Morris, R. R. Arnold, and J. Webster-Cyriaque (2007)
J. Virol. 81, 6032-6042
   Abstract »    Full Text »    PDF »
Epstein-Barr Virus Inhibits Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication in Primary Effusion Lymphomas.
D. Xu, T. Coleman, J. Zhang, A. Fagot, C. Kotalik, L. Zhao, P. Trivedi, C. Jones, and L. Zhang (2007)
J. Virol. 81, 6068-6078
   Abstract »    Full Text »    PDF »
Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 ORF50/Rta Lytic Switch Protein Functions as a Tetramer.
W. Bu, K. D. Carroll, D. Palmeri, and D. M. Lukac (2007)
J. Virol. 81, 5788-5806
   Abstract »    Full Text »    PDF »



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