Science 30 September 1994: Vol. 265. no. 5181, pp. 2088 - 2090 DOI: 10.1126/science.8091231

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Articles

Two mutations of BRCA2 gene at exon and splicing site in a woman who underwent oncogenetic counseling.

M. Pensabene, I. Spagnoletti, I. Capuano, C. Condello, S. Pepe, A. Contegiacomo, G. Lombardi, G. Bevilacqua, and M. A. Caligo (2009)
Ann. Onc. 20, 874-878
 |  Abstract »  |  Full Text »  |  PDF »

Age-dependent penetrance of different germline mutations in the BRCA1 gene.

F Al-Mulla, J M Bland, D Serratt, J Miller, C Chu, and G T Taylor (2009)
J. Clin. Pathol. 62, 350-356
 |  Abstract »  |  Full Text »  |  PDF »

Methionine-Dependence Phenotype in the de novo Pathway in BRCA1 and BRCA2 Mutation Carriers with and without Breast Cancer.

S. Beetstra, G. Suthers, V. Dhillon, C. Salisbury, J. Turner, M. Altree, R. McKinnon, and M. Fenech (2008)
Cancer Epidemiol. Biomarkers Prev. 17, 2565-2571
 |  Abstract »  |  Full Text »  |  PDF »

Hereditary breast cancer: from molecular pathology to tailored therapies.

D S P Tan, C Marchio, and J S Reis-Filho (2008)
J. Clin. Pathol. 61, 1073-1082
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Counseling and Testing for Common Hereditary Breast Cancer Syndromes: A Paper from the 2007 William Beaumont Hospital Symposium on Molecular Pathology.

D. C. Allain (2008)
J. Mol. Diagn. 10, 383-395
 |  Abstract »  |  Full Text »  |  PDF »

CDKN2A/p16 Genetic Test Reporting Improves Early Detection Intentions and Practices in High-Risk Melanoma Families.

L. G. Aspinwall, S. L. Leaf, E. R. Dola, W. Kohlmann, and S. A. Leachman (2008)
Cancer Epidemiol. Biomarkers Prev. 17, 1510-1519
 |  Abstract »  |  Full Text »  |  PDF »

Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations.

C. A. Haiman, C. Hsu, P. I.W. de Bakker, M. Frasco, X. Sheng, D. Van Den Berg, J. T. Casagrande, L. N. Kolonel, L. Le Marchand, S. E. Hankinson, et al. (2008)
Hum. Mol. Genet. 17, 825-834
 |  Abstract »  |  Full Text »  |  PDF »

Cancer genes associated with phenotypes in monoallelic and biallelic mutation carriers: new lessons from old players.

N. Rahman and R. H. Scott (2007)
Hum. Mol. Genet. 16, R60-R66
 |  Abstract »  |  Full Text »  |  PDF »

American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography.

D. Saslow, C. Boetes, W. Burke, S. Harms, M. O. Leach, C. D. Lehman, E. Morris, E. Pisano, M. Schnall, S. Sener, et al. (2007)
CA Cancer J Clin 57, 75-89
 |  Abstract »  |  Full Text »  |  PDF »

Phenocopies in BRCA1 and BRCA2 families: evidence for modifier genes and implications for screening.

A Smith, A Moran, M C Boyd, M Bulman, A Shenton, L Smith, R Iddenden, E R Woodward, F Lalloo, E R Maher, et al. (2007)
J. Med. Genet. 44, 10-15
 |  Abstract »  |  Full Text »  |  PDF »

A large quantity of novel human antisense transcripts detected by LongSAGE.

X. Ge, Q. Wu, Y.-C. Jung, J. Chen, and S. M. Wang (2006)
Bioinformatics 22, 2475-2479
 |  Abstract »  |  Full Text »  |  PDF »

ASCO/SSO Review of Current Role of Risk-Reducing Surgery in Common Hereditary Cancer Syndromes.

J. G. Guillem, W. C. Wood, J. F. Moley, A. Berchuck, B. Y. Karlan, D. G. Mutch, R. F. Gagel, J. Weitzel, M. Morrow, B. L. Weber, et al. (2006)
J. Clin. Oncol. 24, 4642-4660
 |  Abstract »  |  Full Text »  |  PDF »

Metallothionein as a prognostic biomarker in breast cancer..

B.-H. Bay, R. Jin, J. Huang, and P.-H. Tan (2006)
Experimental Biology and Medicine 231, 1516-1521
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Analysis of Chromosome Pairing, Recombination, and Cell Cycle Control during First Meiotic Prophase in Mammals.

P. E. Cohen, S. E. Pollack, and J. W. Pollard (2006)
Endocr. Rev. 27, 398-426
 |  Abstract »  |  Full Text »  |  PDF »

Deliberate Deceit of Family Members: A Challenge to Providers of Clinical Genetics Services.

J. T. Loud, N. E. Weissman, J. A. Peters, R. M. Giusti, B. S. Wilfond, W. Burke, and M. H. Greene (2006)
J. Clin. Oncol. 24, 1643-1646
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Lymphocytes of BRCA1 and BRCA2 germ-line mutation carriers, with or without breast cancer, are not abnormally sensitive to the chromosome damaging effect of moderate folate deficiency.

S. Beetstra, C. Salisbury, J. Turner, M. Altree, R. McKinnon, G. Suthers, and M. Fenech (2006)
Carcinogenesis 27, 517-524
 |  Abstract »  |  Full Text »  |  PDF »

Tumor suppressor genetics.

S. R. Payne and C. J. Kemp (2005)
Carcinogenesis 26, 2031-2045
 |  Abstract »  |  Full Text »  |  PDF »

Population-Based Analysis of Prognostic Factors and Survival in Familial Melanoma.

S. R. Florell, K. M. Boucher, G. Garibotti, J. Astle, R. Kerber, G. Mineau, C. Wiggins, R. D. Noyes, A. Tsodikov, L. A. Cannon-Albright, et al. (2005)
J. Clin. Oncol. 23, 7168-7177
 |  Abstract »  |  Full Text »  |  PDF »

A Haplotype-Based Case-Control Study of BRCA1 and Sporadic Breast Cancer Risk.

M. L. Freedman, K. L. Penney, D. O. Stram, S. Riley, R. McKean-Cowdin, L. Le Marchand, D. Altshuler, and C. A. Haiman (2005)
Cancer Res. 65, 7516-7522
 |  Abstract »  |  Full Text »  |  PDF »

BRCA2 Suppresses Cell Proliferation via Stabilizing MAGE-D1.

X.-x. Tian, D. Rai, J. Li, C. Zou, Y. Bai, D. Wazer, V. Band, and Q. Gao (2005)
Cancer Res. 65, 4747-4753
 |  Abstract »  |  Full Text »  |  PDF »

Bone Marrow Stromal Cell-derived Growth Inhibitor Inhibits Growth and Migration of Breast Cancer Cells via Induction of Cell Cycle Arrest and Apoptosis.

T. Wang, D. Xia, N. Li, C. Wang, T. Chen, T. Wan, G. Chen, and X. Cao (2005)
J. Biol. Chem. 280, 4374-4382
 |  Abstract »  |  Full Text »  |  PDF »

Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility.

S. Kammerer, R. B. Roth, C. R. Hoyal, R. Reneland, G. Marnellos, M. Kiechle, U. Schwarz-Boeger, L. R. Griffiths, F. Ebner, J. Rehbock, et al. (2005)
PNAS 102, 2004-2009
 |  Abstract »  |  Full Text »  |  PDF »

Epidemiology of Male Breast Cancer.

J. R. Weiss, K. B. Moysich, and H. Swede (2005)
Cancer Epidemiol. Biomarkers Prev. 14, 20-26
 |  Abstract »  |  Full Text »  |  PDF »

An Autosome-Wide Scan for Linkage Disequilibrium-Based Association in Sporadic Breast Cancer Cases in Eastern Finland: Three Candidate Regions Found.

J. M. Hartikainen, H. Tuhkanen, V. Kataja, A. M. Dunning, A. Antoniou, P. Smith, A. Arffman, M. Pirskanen, D. F. Easton, M. Eskelinen, et al. (2005)
Cancer Epidemiol. Biomarkers Prev. 14, 75-80
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for a Heritable Component in Death Resulting From Aortic and Mitral Valve Diseases.

B. D. Horne, N. J. Camp, J. B. Muhlestein, and L. A. Cannon-Albright (2004)
Circulation 110, 3143-3148
 |  Abstract »  |  Full Text »  |  PDF »

Oncogenes and Tumor Suppressor Genes in Breast Cancer: Potential Diagnostic and Therapeutic Applications.

C. Osborne, P. Wilson, and D. Tripathy (2004)
Oncologist 9, 361-377
 |  Abstract »  |  Full Text »  |  PDF »

An oncologist-based model of cancer genetic counselling for hereditary breast and ovarian cancer.

A. Contegiacomo, M. Pensabene, I. Capuano, L. Tauchmanova, M. Federico, D. Turchetti, L. Cortesi, P. Marchetti, E. Ricevuto, G. Cianci, et al. (2004)
Ann. Onc. 15, 726-732
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of widely used models for predicting BRCA1 and BRCA2 mutations.

F Marroni, P Aretini, E D'Andrea, M A Caligo, L Cortesi, A Viel, E Ricevuto, M Montagna, G Cipollini, S Ferrari, et al. (2004)
J. Med. Genet. 41, 278-285
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Cancer Risks for Male Carriers of Germline Mutations in BRCA1 or BRCA2: A Review of the Literature.

A. Liede, B. Y. Karlan, and S. A. Narod (2004)
J. Clin. Oncol. 22, 735-742
 |  Abstract »  |  Full Text »  |  PDF »

Phytoestrogen-Rich Diets Modulate Expression of Brca1 and Brca2 Tumor Suppressor Genes in Mammary Glands of Female Wistar Rats.

C. Vissac-Sabatier, V. Coxam, P. Dechelotte, C. Picherit, M.-N. Horcajada, M.-J. Davicco, P. Lebecque, Y.-J. Bignon, and D. Bernard-Gallon (2003)
Cancer Res. 63, 6607-6612
 |  Abstract »  |  Full Text »  |  PDF »

Segregation Analysis of 231 Ashkenazi Jewish Families for Evidence of Additional Breast Cancer Susceptibility Genes.

D. J. Kaufman, T. H. Beaty, and J. P. Struewing (2003)
Cancer Epidemiol. Biomarkers Prev. 12, 1045-1052
 |  Abstract »  |  Full Text »  |  PDF »

Individual and family characteristics associated with protein truncating BRCA1 and BRCA2 mutations in an Ontario population based series from the Cooperative Family Registry for Breast Cancer Studies.

H Ozcelik, J A Knight, G Glendon, H Yazici, N Carson, P J Ainsworth, S A M Taylor, H Feilotter, R F Carter, N F Boyd, et al. (2003)
J. Med. Genet. 40, e91-91
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Ocular Melanoma: A Review and the Relationship to Cutaneous Melanoma.

E. A. Hurst, J. W. Harbour, and L. A. Cornelius (2003)
Arch Dermatol 139, 1067-1073
 |  Abstract »  |  Full Text »  |  PDF »

The role of the tumour suppressor p33ING1b in human neoplasia.

G S Nouman, J J Anderson, J Lunec, and B Angus (2003)
J. Clin. Pathol. 56, 491-496
 |  Abstract »  |  Full Text »  |  PDF »

Downregulation of nuclear expression of the p33ING1b inhibitor of growth protein in invasive carcinoma of the breast.

G S Nouman, J J Anderson, S Crosier, J Shrimankar, J Lunec, and B Angus (2003)
J. Clin. Pathol. 56, 507-511
 |  Abstract »  |  Full Text »  |  PDF »

Breast and Ovarian Cancer.

R. Wooster and B. L. Weber (2003)
N. Engl. J. Med. 348, 2339-2347
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American Cancer Society Guidelines for Breast Cancer Screening: Update 2003.

R. A. Smith, D. Saslow, K. Andrews Sawyer, W. Burke, M. E. Costanza, W. P. Evans III, R. S. Foster Jr., E. Hendrick, H. J. Eyre, and S. Sener (2003)
CA Cancer J Clin 53, 141-169
 |  Abstract »  |  Full Text »  |  PDF »

"Genetic Exceptionalism" in Medicine: Clarifying the Differences between Genetic and Nongenetic Tests.

M. J. Green and J. R. Botkin (2003)
Ann Intern Med 138, 571-575
 |  Abstract »  |  Full Text »  |  PDF »

Intention to Pursue Genetic Testing for Breast Cancer among Women due for Screening Mammography.

K. Gwyn, S. W. Vernon, and P. M. Conoley (2003)
Cancer Epidemiol. Biomarkers Prev. 12, 96-102
 |  Abstract »  |  Full Text »  |  PDF »

Psychosocial Predictors of BRCA Counseling and Testing Decisions among Urban African-American Women.

H. S. Thompson, H. B. Valdimarsdottir, C. Duteau-Buck, J. Guevarra, D. H. Bovbjerg, C. Richmond-Avellaneda, D. Amarel, D. Godfrey, K. Brown, and K. Offit (2002)
Cancer Epidemiol. Biomarkers Prev. 11, 1579-1585
 |  Abstract »  |  Full Text »  |  PDF »

Breast Cancer in Men.

S. H. Giordano, A. U. Buzdar, and G. N. Hortobagyi (2002)
Ann Intern Med 137, 678-687
 |  Abstract »  |  Full Text »  |  PDF »

Sex hormone-binding globulin polymorphisms in familial and sporadic breast cancer.

A. Forsti, Q. Jin, E. Grzybowska, M. Soderberg, H. Zientek, M. Sieminska, J. Rogozinska-Szczepka, E. Chmielik, B. Utracka-Hutka, and K. Hemminki (2002)
Carcinogenesis 23, 1315-1320
 |  Abstract »  |  Full Text »  |  PDF »

Perspective: Prostate Cancer Susceptibility Genes.

J. Simard, M. Dumont, P. Soucy, and F. Labrie (2002)
Endocrinology 143, 2029-2040
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Effect of Prevention Strategies on Survival and Quality-Adjusted Survival of Women With BRCA1/2 Mutations: An Updated Decision Analysis.

V. R. Grann, J. S. Jacobson, D. Thomason, D. Hershman, D. F. Heitjan, and A. I. Neugut (2002)
J. Clin. Oncol. 20, 2520-2529
 |  Abstract »  |  Full Text »  |  PDF »

Genes other than BRCA1 and BRCA2 involved in breast cancer susceptibility.

M M de Jong, I M Nolte, G J te Meerman, W T A van der Graaf, J C Oosterwijk, J H Kleibeuker, M Schaapveld, and E G E de Vries (2002)
J. Med. Genet. 39, 225-242
 |  Abstract »  |  Full Text »  |  PDF »

Infrequent Mutation in the BRCA2 Gene in Esophageal Squamous Cell Carcinoma.

N. Hu, G. Li, W.-J. Li, C. Wang, A. M. Goldstein, Z.-Z. Tang, M. J. Roth, S. M. Dawsey, J. Huang, Q.-H. Wang, et al. (2002)
Clin. Cancer Res. 8, 1121-1126
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Cancer Cell Growth by BRCA2.

S.-C. Wang, R. Shao, A. Y. Pao, S. Zhang, M.-C. Hung, and L.-K. Su (2002)
Cancer Res. 62, 1311-1314
 |  Abstract »  |  Full Text »  |  PDF »

Contribution of BRCA2 germline mutations to hereditary breast/ovarian cancer in Germany.

U Hamann, X Liu, S Lange, H U Ulmer, A Benner, and R J Scott (2002)
J. Med. Genet. 39, e12-12
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BRCA1 and BRCA2 Mutation Frequency in Women Evaluated in a Breast Cancer Risk Evaluation Clinic.

H. A. Shih, F. J. Couch, K. L. Nathanson, M. A. Blackwood, T. R. Rebbeck, K. A. Armstrong, K. Calzone, J. Stopfer, S. Seal, M. R. Stratton, et al. (2002)
J. Clin. Oncol. 20, 994-999
 |  Abstract »  |  Full Text »  |  PDF »

Brca2 (XRCC11) Deficiency Results in Radioresistant DNA Synthesis and a Higher Frequency of Spontaneous Deletions.

M. Kraakman-van der Zwet, W. J. I. Overkamp, R. E. E. van Lange, J. Essers, A. van Duijn-Goedhart, I. Wiggers, S. Swaminathan, P. P. W. van Buul, A. Errami, R. T. L. Tan, et al. (2002)
Mol. Cell. Biol. 22, 669-679
 |  Abstract »  |  Full Text »  |  PDF »

Breast Carcinoma In Situ: Risk Factors and Screening Patterns.

E. B. Claus, M. Stowe, and D. Carter (2001)
J Natl Cancer Inst 93, 1811-1817
 |  Abstract »  |  Full Text »  |  PDF »

Loss of Heterozygosity of the Putative Prostate Cancer Susceptibility Gene HPC2/ELAC2 Is Uncommon in Sporadic and Familial Prostate Cancer.

Y.-Q. Wu, H. Chen, M. A. Rubin, K. J. Wojno, and K. A. Cooney (2001)
Cancer Res. 61, 8651-8653
 |  Abstract »  |  Full Text »  |  PDF »

Inactivation of Human SRBC, Located within the 11p15.5-p15.4 Tumor Suppressor Region, in Breast and Lung Cancers.

X. L. Xu, L. C. Wu, F. Du, A. Davis, M. Peyton, Y. Tomizawa, A. Maitra, G. Tomlinson, A. F. Gazdar, B. E. Weissman, et al. (2001)
Cancer Res. 61, 7943-7949
 |  Abstract »  |  Full Text »  |  PDF »

Loss of Heterozygosity on Chromosomes 3, 9, 13, and 17, Including the Retinoblastoma Locus, in Uveal Melanoma.

A. G. M. Scholes, T. Liloglou, P. Maloney, S. Hagan, J. Nunn, P. Hiscott, B. E. Damato, I. Grierson, and J. K. Field (2001)
Invest. Ophthalmol. Vis. Sci. 42, 2472-2477
 |  Abstract »  |  Full Text »  |  PDF »

Mutational Analysis of the PRL Receptor Gene in Human Breast Tumors with Differential PRL Receptor Protein Expression.

A. Glasow, L.-C. Horn, S. E. Taymans, C. A. Stratakis, P. A. Kelly, U. Kohler, J. Gillespie, B. K. Vonderhaar, and S. R. Bornstein (2001)
J. Clin. Endocrinol. Metab. 86, 3826-3832
 |  Abstract »  |  Full Text »  |  PDF »

The Genetic Epidemiology of Cancer: Interpreting Family and Twin Studies and Their Implications for Molecular Genetic Approaches.

N. Risch (2001)
Cancer Epidemiol. Biomarkers Prev. 10, 733-741
 |  Abstract »  |  Full Text »  |  PDF »

Constitutional Genomic Instability with Inversions, Duplications, and Amplifications in 9p23-24 in BRCA2 Mutation Carriers.

L. Savelyeva, A. Claas, I. Matzner, P. Schlag, W. Hofmann, S. Scherneck, B. Weber, and M. Schwab (2001)
Cancer Res. 61, 5179-5185
 |  Abstract »  |  Full Text »  |  PDF »

High-Resolution Chromosome 3p Allelotyping of Breast Carcinomas and Precursor Lesions Demonstrates Frequent Loss of Heterozygosity and a Discontinuous Pattern of Allele Loss.

A. Maitra, I. I. Wistuba, C. Washington, A. K. Virmani, R. Ashfaq, S. Milchgrub, A. F. Gazdar, and J. D. Minna (2001)
Am. J. Pathol. 159, 119-130
 |  Abstract »  |  Full Text »  |  PDF »

BRCA1 and BRCA2 and the genetics of breast and ovarian cancer.

P. L. Welcsh and M.-C. King (2001)
Hum. Mol. Genet. 10, 705-713
 |  Abstract »  |  Full Text »  |  PDF »

Coping With Grim News From Genetic Tests.

M. Horowitz, E. Sundin, A. Zanko, and R. Lauer (2001)
Psychosomatics 42, 100-105
 |  Abstract »  |  Full Text »

Allelic imbalance on chromosomes 13 and 17 and mutation analysis of BRCA1 and BRCA2 genes in monozygotic twins concordant for breast cancer.

A. Forsti, L. Luo, I. Vorechovsky, M. Soderberg, P. Lichtenstein, and K. Hemminki (2001)
Carcinogenesis 22, 27-33
 |  Abstract »  |  Full Text »  |  PDF »

Randomized Trial of a Specialist Genetic Assessment Service for Familial Breast Cancer.

K. Brain, J. Gray, P. Norman, E. France, C. Anglim, G. Barton, E. Parsons, A. Clarke, H. Sweetland, M. Tischkowitz, et al. (2000)
J Natl Cancer Inst 92, 1345-1351
 |  Abstract »  |  Full Text »  |  PDF »

Why Are the Majority of Hereditary Cases of Early-Onset Breast Cancer Sporadic? A Simulation Study.

J. Cui and J. L. Hopper (2000)
Cancer Epidemiol. Biomarkers Prev. 9, 805-812
 |  Abstract »  |  Full Text »

Genetic and Hormonal Risk Factors in Breast Cancer.

A.-M. Martin and B. L. Weber (2000)
J Natl Cancer Inst 92, 1126-1135
 |  Abstract »  |  Full Text »  |  PDF »

Recurrent Genetic Aberrations in Thymoma and Thymic Carcinoma.

A. Zettl, P. Strobel, K. Wagner, T. Katzenberger, G. Ott, A. Rosenwald, K. Peters, A. Krein, M. Semik, H.-K. Muller-Hermelink, et al. (2000)
Am. J. Pathol. 157, 257-266
 |  Abstract »  |  Full Text »  |  PDF »

Intention to Undergo Prophylactic Bilateral Mastectomy in Women at Increased Risk of Developing Hereditary Breast Cancer.

B. Meiser, P. Butow, M. Friedlander, V. Schnieden, M. Gattas, J. Kirk, G. Suthers, E. Haan, and K. Tucker (2000)
J. Clin. Oncol. 18, 2250-2257
 |  Abstract »  |  Full Text »  |  PDF »

Attitudes to genetic testing for breast cancer susceptibility in women at increased risk of developing hereditary breast cancer.

B. MEISER, P. BUTOW, A. BARRATT, G. SUTHERS, M. SMITH, A. COLLEY, E. THOMPSON, and K. TUCKER (2000)
J. Med. Genet. 37, 472-476
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Relevance of the Viral RAK Alpha Gene in Diagnosis of Malignant Versus Nonmalignant Tumors of the Ovary and Uterus.

E. M. Rakowicz-Szulczynska (2000)
Clin. Vaccine Immunol. 7, 360-365
 |  Abstract »  |  Full Text »  |  PDF »

Chromosome 8p alterations in sporadic and BRCA2 999del5 linked breast cancer.

B. I. Sigbjörnsdottir, G. Ragnarsson, B. A. Agnarsson, C. Huiping, R. B. Barkardottir, V. Egilsson, and S. Ingvarsson (2000)
J. Med. Genet. 37, 342-347
 |  Abstract »  |  Full Text »

Establishment of a radiation- and estrogen-induced breast cancer model.

G. M. Calaf and T. K. Hei (2000)
Carcinogenesis 21, 769-776
 |  Abstract »  |  Full Text »  |  PDF »

A model protocol evaluating the introduction of genetic assessment for women with a family history of breast cancer.

J. Gray, K. Brain, P. Norman, C. Anglim, L. France, G. Barton, L. Branston, E. Parsons, A. Clarke, J. Sampson, et al. (2000)
J. Med. Genet. 37, 192-196
 |  Abstract »  |  Full Text »

Why do women attend familial breast cancer clinics?.

K. Brain, J. Gray, P. Norman, E. Parsons, A. Clarke, C. Rogers, R. Mansel, and P. Harper (2000)
J. Med. Genet. 37, 197-202
 |  Abstract »  |  Full Text »

Management of Breast Cancer After Hodgkin’s Disease.

S. L. Wolden, S. L. Hancock, R. W. Carlson, D. R. Goffinet, S. S. Jeffrey, and R. T. Hoppe (2000)
J. Clin. Oncol. 18, 765
 |  Abstract »  |  Full Text »  |  PDF »

Chromosomal Instability and Cancer Predisposition: Insights from Studies on the Breast Cancer Susceptibility Gene, BRCA2.

A.R. VENKITARAMAN (2000)
Cold Spring Harb Symp Quant Biol 65, 567-572
 |  Abstract »  |  PDF »

Genetic Polymorphisms and Risk of Breast Cancer.

S. S. Coughlin and M. Piper (1999)
Cancer Epidemiol. Biomarkers Prev. 8, 1023-1032
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CT of Epithelial Ovarian Tumors.

S. Kawamoto, B. A. Urban, and E. K. Fishman (1999)
RadioGraphics 19, 85-102
 |  Abstract »  |  Full Text »

Linkage analysis of 56 multiplex families excludes the Cowden disease gene PTEN as a major contributor to familial breast cancer.

Y. Y. SHUGART, C. COUR, H. RENARD, G. LENOIR, D. GOLDGAR, D. TEARE, D. EASTON, N. RAHMAN, R. GUSTERTON, S. SEAL, et al. (1999)
J. Med. Genet. 36, 720-721
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DNA Copy Number Losses in Human Neoplasms.

S. Knuutila, Y. Aalto, K. Autio, A.-M. Bjorkqvist, W.'e. El-Rifai, S. Hemmer, T. Huhta, E. Kettunen, S. Kiuru-Kuhlefelt, M. L. Larramendy, et al. (1999)
Am. J. Pathol. 155, 683-694
 |  Abstract »  |  Full Text »  |  PDF »

Mammographic Densities and Risk of Breast Cancer Among Subjects With a Family History of This Disease.

N. F. Boyd, G. A. Lockwood, L. J. Martin, J. A. Knight, R. A. Jong, E. Fishell, J. W. Byng, M. J. Yaffe, and D. L. Tritchler (1999)
J Natl Cancer Inst 91, 1404-1408
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of a Shared Decision Making Program for Women Suspected to Have a Genetic Predisposition to Breast Cancer: Preliminary Results.

P. F.M. Stalmeier, I. J. Unic, L. C.G. Verhoef, and W. A.J. Van Daal (1999)
Med Decis Making 19, 230-241
 |  Abstract »  |  PDF »

Lymph Node Metastasis Is Associated with Allelic Loss on Chromosome 13q12-13 in Esophageal Squamous Cell Carcinoma1.

H. Harada, H. Tanaka, Y. Shimada, M. Shinoda, M. Imamura, and K. Ishizaki (1999)
Cancer Res. 59, 3724-3729
 |  Abstract »  |  Full Text »  |  PDF »

Prevalence of BRCA1 and BRCA2 Gene Mutations in Patients With Early-Onset Breast Cancer.

J. Peto, N. Collins, R. Barfoot, S. Seal, W. Warren, N. Rahman, D. F. Easton, C. Evans, J. Deacon, and M. R. Stratton (1999)
J Natl Cancer Inst 91, 943-949
 |  Abstract »  |  Full Text »  |  PDF »

Tamoxifen, Raloxifene, and the Prevention of Breast Cancer.

V. C. Jordan and M. Morrow (1999)
Endocr. Rev. 20, 253-278
 |  Abstract »  |  Full Text »

Risk factors for detecting germline BRCA1 and BRCA2 founder mutations in Ashkenazi Jewish women with breast or ovarian cancer.

S. V Hodgson, E. Heap, J. Cameron, D. Ellis, C. G Mathew, R. A Eeles, E. Solomon, and C. M Lewis (1999)
J. Med. Genet. 36, 369-373
 |  Abstract »  |  Full Text »

Chromosome 13q Deletion Mapping in Pituitary Tumors: Infrequent Loss of the Retinoblastoma Susceptibility Gene (RB1) Locus Despite Loss of RB1 Protein Product in Somatotrophinomas.

D. J. Simpson, J. Magnay, J. E. Bicknell, A. L. Barkan, A. M. McNicol, R. N. Clayton, and W. E. Farrell (1999)
Cancer Res. 59, 1562-1566
 |  Abstract »  |  Full Text »  |  PDF »

The BRCA2 gene product functionally interacts with p53 and RAD51.

L. Y. Marmorstein, T. Ouchi, and S. A. Aaronson (1998)
PNAS 95, 13869-13874
 |  Abstract »  |  Full Text »  |  PDF »

Hereditary Factors in Gynecologic Cancer.

H. T. Lynch, M. J. Casey, T. G. Shaw, and J. F. Lynch (1998)
Oncologist 3, 319-338
 |  Abstract »  |  Full Text »

Human Immunodeficiency Virus Type 1-Like DNA Sequences and Immunoreactive Viral Particles with Unique Association with Breast Cancer.

E. M. Rakowicz-Szulczynska, B. Jackson, A. M. Szulczynska, and M. Smith (1998)
Clin. Vaccine Immunol. 5, 645-653
 |  Abstract »  |  Full Text »

In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanoma.

G. P. Robertson, F. B. Furnari, M. E. Miele, M. J. Glendening, D. R. Welch, J. W. Fountain, T. G. Lugo, H.-J. S. Huang, and W. K. Cavenee (1998)
PNAS 95, 9418-9423
 |  Abstract »  |  Full Text »  |  PDF »

Breast and Prostate Cancer: An Analysis of Common Epidemiological, Genetic, and Biochemical Features.

C. Lopez-Otin and E. P. Diamandis (1998)
Endocr. Rev. 19, 365-396
 |  Abstract »  |  Full Text »  |  PDF »

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment.

P.-L. Chen, C.-F. Chen, Y. Chen, J. Xiao, Z. D. Sharp, and W.-H. Lee (1998)
PNAS 95, 5287-5292
 |  Abstract »  |  Full Text »  |  PDF »

Thioredoxin Peroxidase Is a Novel Inhibitor of Apoptosis with a Mechanism Distinct from That of Bcl-2.

P. Zhang, B. Liu, S. W. Kang, M. S. Seo, S. G. Rhee, and L. M. Obeid (1997)
J. Biol. Chem. 272, 30615-30618
 |  Abstract »  |  Full Text »  |  PDF »

Human Cancer Syndromes: Clues to the Origin and Nature of Cancer.

E. R. Fearon (1997)
Science 278, 1043-1050
 |  Abstract »  |  Full Text »

Recombination Hot Spots and Human Disease.

S. M. Purandare and P. I. Patel (1997)
Genome Res. 7, 773-786
 |  Full Text »  |  PDF »

Genetic Testing for Cancer Risk Assessment: A Review.

L. Grogan and I.R. Kirsch (1997)
Oncologist 2, 208-222
 |  Abstract »  |  Full Text »  |  PDF »

Direct isolation of human BRCA2 gene by transformation-associated recombination in yeast.

V. Larionov, N. Kouprina, G. Solomon, J. C. Barrett, and M. A. Resnick (1997)
PNAS 94, 7384-7387
 |  Abstract »  |  Full Text »  |  PDF »

From Bench to Bedside ... But When?.

C. Eng (1997)
Genome Res. 7, 669-672
 |  Full Text »  |  PDF »

The Risk of Cancer Associated with Specific Mutations of BRCA1 and BRCA2 among Ashkenazi Jews.

J. P. Struewing, P. Hartge, S. Wacholder, S. M. Baker, M. Berlin, M. McAdams, M. M. Timmerman, L. C. Brody, and M. A. Tucker (1997)
N. Engl. J. Med. 336, 1401-1408
 |  Abstract »  |  Full Text »  |  PDF »

BRCA1 Mutations in Women Attending Clinics That Evaluate the Risk of Breast Cancer.

F. J. Couch, M. L. DeShano, M. A. Blackwood, K. Calzone, J. Stopfer, L. Campeau, A. Ganguly, T. Rebbeck, B. L. Weber, L. Jablon, et al. (1997)
N. Engl. J. Med. 336, 1409-1415
 |  Abstract »  |  Full Text »  |  PDF »

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