Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 23 September 1994:
Vol. 265. no. 5180, pp. 1885 - 1888
DOI: 10.1126/science.8091215
Prev | Table of Contents | Next

Articles

Science, Vol 265, Issue 5180, 1885-1888
Copyright © 1994 by American Association for the Advancement of Science

articles

Laminar comparison of somatosensory cortical plasticity

ME Diamond, W Huang, and FF Ebner

Department of Sciences and Biomedical Technologies, University of Udine, Italy.

During tactile learning there is a transformation in the way the primary somatosensory cortex integrates, represents, and distributes information from the skin. To define this transformation, the site of earliest modification has been identified in rat somatosensory cortex after a change in sensory experience. Afferent activity was manipulated by clipping all except two whiskers on one side of the snout ("whisker pairing"), and the receptive fields of neurons at different cortical depths were mapped 24 hours later. Neurons in layer IV, the target of the primary thalamic pathway, were unaltered, whereas neurons located above and below layer IV showed significant changes. These changes were similar to those that occur in layer IV after longer periods of whisker pairing. The findings support the hypothesis that the layers of cortex contribute differently to plasticity. Neurons in the supragranular and infragranular layers respond rapidly to changes in sensory experience and may contribute to subsequent modification in layer IV.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Sensory Experience Alters Specific Branches of Individual Corticocortical Axons during Development.
R. M. Bruno, T. T. G. Hahn, D. J. Wallace, C. P. J. de Kock, and B. Sakmann (2009)
J. Neurosci. 29, 3172-3181
   Abstract »    Full Text »    PDF »
Intrinsic Signal Imaging of Deprivation-Induced Contraction of Whisker Representations in Rat Somatosensory Cortex.
P. J. Drew and D. E. Feldman (2009)
Cereb Cortex 19, 331-348
   Abstract »    Full Text »    PDF »
A dynamic zone defines interneuron remodeling in the adult neocortex.
W.-C. A. Lee, J. L. Chen, H. Huang, J. H. Leslie, Y. Amitai, P. T. So, and E. Nedivi (2008)
PNAS 105, 19968-19973
   Abstract »    Full Text »    PDF »
Altered Sensory Experience Induces Targeted Rewiring of Local Excitatory Connections in Mature Neocortex.
C. E. J. Cheetham, M. S. L. Hammond, R. McFarlane, and G. T. Finnerty (2008)
J. Neurosci. 28, 9249-9260
   Abstract »    Full Text »    PDF »
Disruption of Balanced Cortical Excitation and Inhibition by Acoustic Trauma.
B. Scholl and M. Wehr (2008)
J Neurophysiol 100, 646-656
   Abstract »    Full Text »    PDF »
Computational Role of Large Receptive Fields in the Primary Somatosensory Cortex.
G. Foffani, J. K. Chapin, and K. A. Moxon (2008)
J Neurophysiol 100, 268-280
   Abstract »    Full Text »    PDF »
Unsupervised Whisker Tracking in Unrestrained Behaving Animals.
J. Voigts, B. Sakmann, and T. Celikel (2008)
J Neurophysiol 100, 504-515
   Abstract »    Full Text »    PDF »
Critical Period Plasticity of Axonal Arbors of Layer 2/3 Pyramidal Neurons in Rat Somatosensory Cortex: Layer-Specific Reduction of Projections into Deprived Cortical Columns.
P. Broser, V. Grinevich, P. Osten, B. Sakmann, and D. J. Wallace (2008)
Cereb Cortex 18, 1588-1603
   Abstract »    Full Text »    PDF »
Plasticity of Representational Maps in Somatosensory Cortex Observed by In Vivo Voltage-Sensitive Dye Imaging.
D. J. Wallace and B. Sakmann (2008)
Cereb Cortex 18, 1361-1373
   Abstract »    Full Text »    PDF »
Ipsilateral Whiskers Suppress Experience-Dependent Plasticity in the Barrel Cortex.
S. Glazewski, B. L. Benedetti, and A. L. Barth (2007)
J. Neurosci. 27, 3910-3920
   Abstract »    Full Text »    PDF »
Sensory Experience Alters Cortical Connectivity and Synaptic Function Site Specifically.
C. E. J. Cheetham, M. S. L. Hammond, C. E. J. Edwards, and G. T. Finnerty (2007)
J. Neurosci. 27, 3456-3465
   Abstract »    Full Text »    PDF »
Spike Timing-Dependent Synaptic Depression in the In Vivo Barrel Cortex of the Rat.
V. Jacob, D. J. Brasier, I. Erchova, D. Feldman, and D. E. Shulz (2007)
J. Neurosci. 27, 1271-1284
   Abstract »    Full Text »    PDF »
Sensory integration across space and in time for decision making in the somatosensory system of rodents.
T. Celikel and B. Sakmann (2007)
PNAS 104, 1395-1400
   Abstract »    Full Text »    PDF »
Map Plasticity in Somatosensory Cortex.
D. E. Feldman and M. Brecht (2005)
Science 310, 810-815
   Abstract »    Full Text »    PDF »
Chronic Suppression of Activity in Barrel Field Cortex Downregulates Sensory Responses in Contralateral Barrel Field Cortex.
L. Li, V. Rema, and F. F. Ebner (2005)
J Neurophysiol 94, 3342-3356
   Abstract »    Full Text »    PDF »
Laminar and Columnar Organization of Ascending Excitatory Projections to Layer 2/3 Pyramidal Neurons in Rat Barrel Cortex.
G. M. G. Shepherd and K. Svoboda (2005)
J. Neurosci. 25, 5670-5679
   Abstract »    Full Text »    PDF »
Timing-dependent plasticity in human primary somatosensory cortex.
A. Wolters, A. Schmidt, A. Schramm, D. Zeller, M. Naumann, E. Kunesch, R. Benecke, K. Reiners, and J. Classen (2005)
J. Physiol. 565, 1039-1052
   Abstract »    Full Text »    PDF »
Layer-specific Production of Nitric Oxide during Cortical Circuit Formation in Postnatal Mouse Brain.
T. Imura, S. Kanatani, S. Fukuda, Y. Miyamoto, and T. Hisatsune (2005)
Cereb Cortex 15, 332-340
   Abstract »    Full Text »    PDF »
A semi-persistent adult ocular dominance plasticity in visual cortex is stabilized by activated CREB.
T. A. Pham, S. J. Graham, S. Suzuki, A. Barco, E. R. Kandel, B. Gordon, and M. E. Lickey (2004)
Learn. Mem. 11, 738-747
   Abstract »    Full Text »    PDF »
Stimulus-Induced Intercolumnar Synchronization of Neuronal Activity in Rat Barrel Cortex: A Laminar Analysis.
M. Zhang and K. D. Alloway (2004)
J Neurophysiol 92, 1464-1478
   Abstract »    Full Text »    PDF »
Development of Intrinsic Properties and Excitability of Layer 2/3 Pyramidal Neurons During a Critical Period for Sensory Maps in Rat Barrel Cortex.
M. Maravall, E. A. Stern, and K. Svoboda (2004)
J Neurophysiol 92, 144-156
   Abstract »    Full Text »    PDF »
Rapid Fluctuations in Rat Barrel Cortex Plasticity.
I. A. Erchova and M. E. Diamond (2004)
J. Neurosci. 24, 5931-5941
   Abstract »    Full Text »    PDF »
Experience-dependent Changes in Basal Dendritic Branching of Layer 2/3 Pyramidal Neurons During a Critical Period for Developmental Plasticity in Rat Barrel Cortex.
M. Maravall, I. Y.Y. Koh, W. B. Lindquist, and K. Svoboda (2004)
Cereb Cortex 14, 655-664
   Abstract »    Full Text »    PDF »
Synaptic Changes in Layer 2/3 Underlying Map Plasticity of Developing Barrel Cortex.
C. C. H. Petersen, M. Brecht, T. T. G. Hahn, and B. Sakmann (2004)
Science 304, 739-742
   Abstract »    Full Text »    PDF »
Monocular Enucleation Induces Nuclear Localization of Calcium/Calmodulin-Dependent Protein Kinase IV in Cortical Interneurons of Adult Monkey Area V1.
J. Lalonde, P. E. D. Lachance, and A. Chaudhuri (2004)
J. Neurosci. 24, 554-564
   Abstract »    Full Text »    PDF »
Lesions of Mature Barrel Field Cortex Interfere with Sensory Processing and Plasticity in Connected Areas of the Contralateral Hemisphere.
V. Rema and F. F. Ebner (2003)
J. Neurosci. 23, 10378-10387
   Abstract »    Full Text »    PDF »
Experience-dependent Regulation of the Zincergic Innervation of Visual Cortex in Adult Monkeys.
R. H. Dyck, A. Chaudhuri, and M. S. Cynader (2003)
Cereb Cortex 13, 1094-1109
   Abstract »    Full Text »    PDF »
Band-Pass Response Properties of Rat SI Neurons.
C. E. Garabedian, S. R. Jones, M. M. Merzenich, A. Dale, and C. I. Moore (2003)
J Neurophysiol 90, 1379-1391
   Abstract »    Full Text »    PDF »
Developmental Regulation of Plasticity in the Forepaw Representation of Ferret Somatosensory Cortex.
D. F. McLaughlin and S. L. Juliano (2003)
J Neurophysiol 89, 2289-2298
   Abstract »    Full Text »    PDF »
Cell Type-Specific Circuits of Cortical Layer IV Spiny Neurons.
D. Schubert, R. Kotter, K. Zilles, H. J. Luhmann, and J. F. Staiger (2003)
J. Neurosci. 23, 2961-2970
   Abstract »    Full Text »    PDF »
Columnar Transformations in Auditory Cortex? A Comparison to Visual and Somatosensory Cortices.
J. F. Linden and C. E. Schreiner (2003)
Cereb Cortex 13, 83-89
   Abstract »    Full Text »    PDF »
Experience-Dependent Plasticity Is Impaired in Adult Rat Barrel Cortex after Whiskers Are Unused in Early Postnatal Life.
V. Rema, M. Armstrong-James, and F. F. Ebner (2003)
J. Neurosci. 23, 358-366
   Abstract »    Full Text »    PDF »
Adult Experience-dependent Plasticity of S1 Barrel Cortex in the Normal and Monoamine Oxidase-A Knockout (Tg8) Mouse.
Z. Yang, I. Seif, and M. Armstrong-James (2002)
Cereb Cortex 12, 1269-1279
   Abstract »    Full Text »    PDF »
Rapid, Experience-Dependent Changes in Levels of Synaptic Zinc in Primary Somatosensory Cortex of the Adult Mouse.
C. E. Brown and R. H. Dyck (2002)
J. Neurosci. 22, 2617-2625
   Abstract »    Full Text »    PDF »
Functionally Independent Columns of Rat Somatosensory Barrel Cortex Revealed with Voltage-Sensitive Dye Imaging.
C. C. H. Petersen and B. Sakmann (2001)
J. Neurosci. 21, 8435-8446
   Abstract »    Full Text »    PDF »
The Role of Cortical Activity in Experience-Dependent Potentiation and Depression of Sensory Responses in Rat Barrel Cortex.
H. Wallace, S. Glazewski, K. Liming, and K. Fox (2001)
J. Neurosci. 21, 3881-3894
   Abstract »    Full Text »    PDF »
Imaging High-Resolution Structure of GFP-Expressing Neurons in Neocortex In Vivo.
B. E. Chen, B. Lendvai, E. A. Nimchinsky, B. Burbach, K. Fox, and K. Svoboda (2000)
Learn. Mem. 7, 433-441
   Abstract »    Full Text »
The Excitatory Neuronal Network of Rat Layer 4 Barrel Cortex.
C. C. H. Petersen and B. Sakmann (2000)
J. Neurosci. 20, 7579-7586
   Abstract »    Full Text »    PDF »
Upregulation of cAMP Response Element-Mediated Gene Expression during Experience-Dependent Plasticity in Adult Neocortex.
A. L. Barth, M. McKenna, S. Glazewski, P. Hill, S. Impey, D. Storm, and K. Fox (2000)
J. Neurosci. 20, 4206-4216
   Abstract »    Full Text »    PDF »
Rapid Extragranular Plasticity in the Absence of Thalamocortical Plasticity in the Developing Primary Visual Cortex.
J. T. Trachtenberg, C. Trepel, and M. P. Stryker (2000)
Science 287, 2029-2032
   Abstract »    Full Text »
Experience-dependent Plasticity of Rat Barrel Cortex: Redistribution of Activity across Barrel-columns.
M. A. Lebedev, G. Mirabella, I. Erchova, and M. E. Diamond (2000)
Cereb Cortex 10, 23-31
   Abstract »    Full Text »    PDF »
Effect of Enriched Environment Rearing on Impairments in Cortical Excitability and Plasticity after Prenatal Alcohol Exposure.
V. Rema and F. F. Ebner (1999)
J. Neurosci. 19, 10993-11006
   Abstract »    Full Text »    PDF »
Distinct Functional Types of Associative Long-Term Potentiation in Neocortical and Hippocampal Pyramidal Neurons.
D. V. Buonomano (1999)
J. Neurosci. 19, 6748-6754
   Abstract »    Full Text »    PDF »
Distribution of tactile learning and its neural basis.
J. A. Harris, R. S. Petersen, and M. E. Diamond (1999)
PNAS 96, 7587-7591
   Abstract »    Full Text »    PDF »
Synchronization of Local Neural Networks in the Somatosensory Cortex: A Comparison of Stationary and Moving Stimuli.
S. Roy and K. D. Alloway (1999)
J Neurophysiol 81, 999-1013
   Abstract »    Full Text »    PDF »
Spatio-Temporal Subthreshold Receptive Fields in the Vibrissa Representation of Rat Primary Somatosensory Cortex.
C. I. Moore and S. B. Nelson (1998)
J Neurophysiol 80, 2882-2892
   Abstract »    Full Text »    PDF »
Contribution of Supragranular Layers to Sensory Processing and Plasticity in Adult Rat Barrel Cortex.
W. Huang, M. Armstrong-James, V. Rema, M. E. Diamond, and F. F. Ebner (1998)
J Neurophysiol 80, 3261-3271
   Abstract »    Full Text »    PDF »
Experience-Dependent Plasticity of Adult Rat S1 Cortex Requires Local NMDA Receptor Activation.
V. Rema, M. Armstrong-James, and F. F. Ebner (1998)
J. Neurosci. 18, 10196-10206
   Abstract »    Full Text »    PDF »
Role of the Basal Forebrain Cholinergic Projection in Somatosensory Cortical Plasticity.
R. N. S. Sachdev, S.-M. Lu, R. G. Wiley, and F. F. Ebner (1998)
J Neurophysiol 79, 3216-3228
   Abstract »    Full Text »    PDF »
Temporal Modulation of Spatial Borders in Rat Barrel Cortex.
B. R. Sheth, C. I. Moore, and M. Sur (1998)
J Neurophysiol 79, 464-470
   Abstract »    Full Text »    PDF »
A Focal Zone of Thalamic Plasticity.
J. L. Parker, M. L. Wood, and J. O. Dostrovsky (1998)
J. Neurosci. 18, 548-558
   Abstract »    Full Text »    PDF »
Immediate and simultaneous sensory reorganization at cortical and subcortical levels of the somatosensory system.
B. M. Faggin, K. T. Nguyen, and M. A. L. Nicolelis (1997)
PNAS 94, 9428-9433
   Abstract »    Full Text »    PDF »
Effects of Regional Anesthesia on Phantom Limb Pain Are Mirrored in Changes in Cortical Reorganization.
N. Birbaumer, W. Lutzenberger, P. Montoya, W. Larbig, K. Unertl, S. Topfner, W. Grodd, E. Taub, and H. Flor (1997)
J. Neurosci. 17, 5503-5508
   Abstract »    Full Text »    PDF »
Theory for normal and impaired experience-dependent plasticity in neocortex of adult rats.
L. Benuskova, V. Rema, M. Armstrong-James, and F. F. Ebner (2001)
PNAS 98, 2797-2802
   Abstract »    Full Text »    PDF »
Sensory deprivation without competition yields modest alterations of short-term synaptic dynamics.
G. T. Finnerty and B. W. Connors (2000)
PNAS 97, 12864-12868
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)