Science 16 September 1994: Vol. 265. no. 5179, pp. 1713 - 1716 DOI: 10.1126/science.8085158

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Articles

An integrin-{alpha}4-14-3-3{zeta}-paxillin ternary complex mediates localised Cdc42 activity and accelerates cell migration.

N. O. Deakin, M. D. Bass, S. Warwood, J. Schoelermann, Z. Mostafavi-Pour, D. Knight, C. Ballestrem, and M. J. Humphries (2009)
J. Cell Sci. 122, 1654-1664
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Regulatory Mechanism of Myosin Light Chain Phosphorylation via Binding of 14-3-3 to Myosin Phosphatase.

Y. Koga and M. Ikebe (2008)
Mol. Biol. Cell 19, 1062-1071
 |  Abstract »  |  Full Text »  |  PDF »

Protection against beta-Amyloid-induced Apoptosis by Peptides Interacting with beta-Amyloid.

T. J. Nelson and D. L. Alkon (2007)
J. Biol. Chem. 282, 31238-31249
 |  Abstract »  |  Full Text »  |  PDF »

Cdc37p Is Required for Stress-Induced High-Osmolarity Glycerol and Protein Kinase C Mitogen-Activated Protein Kinase Pathway Functionality by Interaction with Hog1p and Slt2p (Mpk1p).

P. Hawle, D. Horst, J. P. Bebelman, X. X. Yang, M. Siderius, and S. M. van der Vies (2007)
Eukaryot. Cell 6, 521-532
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Structural basis for protein-protein interactions in the 14-3-3 protein family.

X. Yang, W. H. Lee, F. Sobott, E. Papagrigoriou, C. V. Robinson, J. G. Grossmann, M. Sundstrom, D. A. Doyle, and J. M. Elkins (2006)
PNAS 103, 17237-17242
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Function of 14-3-3 Protein: 14-3-3{zeta} Is a Heat-Shock-related Molecular Chaperone That Dissolves Thermal-aggregated Proteins.

M. Yano, S. Nakamuta, X. Wu, Y. Okumura, and H. Kido (2006)
Mol. Biol. Cell 17, 4769-4779
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 Isoforms Are Induced by Aldosterone and Participate in Its Regulation of Epithelial Sodium Channels.

X. Liang, K. W. Peters, M. B. Butterworth, and R. A. Frizzell (2006)
J. Biol. Chem. 281, 16323-16332
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 Proteins: A Number of Functions for a Numbered Protein.

D. Bridges and G. B. G. Moorhead (2005)
Sci. STKE 2005, re10
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Inhibition of Gap Junction Activity through the Release of the C1B Domain of Protein Kinase C{gamma} (PKC{gamma}) from 14-3-3: IDENTIFICATION OF PKC{gamma}-BINDING SITES.

T. A. Nguyen, L. J. Takemoto, and D. J. Takemoto (2004)
J. Biol. Chem. 279, 52714-52725
 |  Abstract »  |  Full Text »  |  PDF »

Sensitivity of 14-3-3 protein test varies in subtypes of sporadic Creutzfeldt-Jakob disease.

R. J. Castellani, M. Colucci, Z. Xie, W. Zou, C. Li, P. Parchi, S. Capellari, M. Pastore, M. H. Rahbar, S. G. Chen, et al. (2004)
Neurology 63, 436-442
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 Proteins: A Number of Functions for a Numbered Protein.

D. Bridges and G. B. G. Moorhead (2004)
Sci. STKE 2004, re10
 |  Abstract »  |  Full Text »  |  PDF »

Cation Diffusion Facilitator Proteins Modulate Raf-1 Activity.

T. Jirakulaporn and A. J. Muslin (2004)
J. Biol. Chem. 279, 27807-27815
 |  Abstract »  |  Full Text »  |  PDF »

Dynamic Changes in C-Raf Phosphorylation and 14-3-3 Protein Binding in Response to Growth Factor Stimulation: DIFFERENTIAL ROLES OF 14-3-3 PROTEIN BINDING SITES.

M. Hekman, S. Wiese, R. Metz, S. Albert, J. Troppmair, J. Nickel, M. Sendtner, and U. R. Rapp (2004)
J. Biol. Chem. 279, 14074-14086
 |  Abstract »  |  Full Text »  |  PDF »

YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3{zeta}.

C. Preisinger, B. Short, V. De Corte, E. Bruyneel, A. Haas, R. Kopajtich, J. Gettemans, and F. A. Barr (2004)
J. Cell Biol. 164, 1009-1020
 |  Abstract »  |  Full Text »  |  PDF »

Trihydrophobin 1 Is a New Negative Regulator of A-Raf Kinase.

W. Liu, X. Shen, Y. Yang, X. Yin, J. Xie, J. Yan, J. Jiang, W. Liu, H. Wang, M. Sun, et al. (2004)
J. Biol. Chem. 279, 10167-10175
 |  Abstract »  |  Full Text »  |  PDF »

Blue-Light- and Phosphorylation-Dependent Binding of a 14-3-3 Protein to Phototropins in Stomatal Guard Cells of Broad Bean.

T. Kinoshita, T. Emi, M. Tominaga, K. Sakamoto, A. Shigenaga, M. Doi, and K.-i. Shimazaki (2003)
Plant Physiology 133, 1453-1463
 |  Abstract »  |  Full Text »

Identification of the Insulin-Regulated Interaction of Phosphodiesterase 3B With 14-3-3 {beta} Protein.

H. Onuma, H. Osawa, K. Yamada, T. Ogura, F. Tanabe, D. K. Granner, and H. Makino (2002)
Diabetes 51, 3362-3367
 |  Abstract »  |  Full Text »  |  PDF »

MADM, a Novel Adaptor Protein That Mediates Phosphorylation of the 14-3-3 Binding Site of Myeloid Leukemia Factor 1.

R. Lim, L. N. Winteringham, J. H. Williams, R. K. McCulloch, E. Ingley, J. Y-H. Tiao, J.-P. Lalonde, S. Tsai, P. A. Tilbrook, Y. Sun, et al. (2002)
J. Biol. Chem. 277, 40997-41008
 |  Abstract »  |  Full Text »  |  PDF »

The 14-3-3 Proteins Rad24 and Rad25 Negatively Regulate Byr2 by Affecting Its Localization in Schizosaccharomyces pombe.

F. Ozoe, R. Kurokawa, Y. Kobayashi, H. T. Jeong, K. Tanaka, K. Sen, T. Nakagawa, H. Matsuda, and M. Kawamukai (2002)
Mol. Cell. Biol. 22, 7105-7119
 |  Abstract »  |  Full Text »  |  PDF »

The 14-3-3 Protein Homologues from Saccharomyces cerevisiae, Bmh1p and Bmh2p, Have Cruciform DNA-binding Activity and Associate in Vivo with ARS307.

M. Callejo, D. Alvarez, G. B. Price, and M. Zannis-Hadjopoulos (2002)
J. Biol. Chem. 277, 38416-38423
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 Antagonizes Ras-Mediated Raf-1 Recruitment to the Plasma Membrane To Maintain Signaling Fidelity.

Y. Light, H. Paterson, and R. Marais (2002)
Mol. Cell. Biol. 22, 4984-4996
 |  Abstract »  |  Full Text »  |  PDF »

Structural Determinants of Ras-Raf Interaction Analyzed in Live Cells.

T. Bondeva, A. Balla, P. Varnai, and T. Balla (2002)
Mol. Biol. Cell 13, 2323-2333
 |  Abstract »  |  Full Text »  |  PDF »

Consummating Signal Transduction: The Role of 14-3-3 Proteins in the Completion of Signal-Induced Transitions in Protein Activity.

P. C. Sehnke, J. M. DeLille, and R. J. Ferl (2002)
PLANT CELL 14, S339-354
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MRK, a Mixed Lineage Kinase-related Molecule That Plays a Role in gamma -Radiation-induced Cell Cycle Arrest.

E. A. Gross, M. G. Callow, L. Waldbaum, S. Thomas, and R. Ruggieri (2002)
J. Biol. Chem. 277, 13873-13882
 |  Abstract »  |  Full Text »  |  PDF »

Transcription Factors Dial 14-3-3 for Nuclear Shuttle.

N. A. Eckardt (2001)
PLANT CELL 13, 2385-2389
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Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions.

G. Pearson, F. Robinson, T. Beers Gibson, B.-e Xu, M. Karandikar, K. Berman, and M. H. Cobb (2001)
Endocr. Rev. 22, 153-183
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Limited Redundancy of Survival Signals from the Type 1 Insulin-Like Growth Factor Receptor.

M. Navarro and R. Baserga (2001)
Endocrinology 142, 1073-1081
 |  Abstract »  |  Full Text »  |  PDF »

Small GTP-Binding Proteins.

Y. Takai, T. Sasaki, and T. Matozaki (2001)
Physiol Rev 81, 153-208
 |  Abstract »  |  Full Text »  |  PDF »

Role of the {beta} isoform of 14-3-3 proteins in cellular proliferation and oncogenic transformation.

Y. Takihara, Y. Matsuda, and J. Hara (2000)
Carcinogenesis 21, 2073-2077
 |  Abstract »  |  Full Text »  |  PDF »

Isoform-Specific Localization of A-RAF in Mitochondria.

A. Yuryev, M. Ono, S. A. Goff, F. Macaluso, and L. P. Wennogle (2000)
Mol. Cell. Biol. 20, 4870-4878
 |  Abstract »  |  Full Text »

Modulation of Human DNA Topoisomerase IIalpha Function by Interaction with 14-3-3epsilon.

E. U. Kurz, K. B. Leader, D. J. Kroll, M. Clark, and F. Gieseler (2000)
J. Biol. Chem. 275, 13948-13954
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of the 14-3-3 Binding Site within the B-Raf Kinase Domain Uncouples Catalytic Activity from PC12 Cell Differentiation.

M. C. MacNicol, A. J. Muslin, and A. M. MacNicol (2000)
J. Biol. Chem. 275, 3803-3809
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of the Roles of 14-3-3 in the Platelet Glycoprotein Ib-IX-mediated Activation of Integrin {alpha}IIb{beta}3 Using a Reconstituted Mammalian Cell Expression Model.

M. Gu, X. Xi, G. D. Englund, M. C. Berndt, and X. Du (1999)
J. Cell Biol. 147, 1085-1096
 |  Abstract »  |  Full Text »  |  PDF »

The Cytoplasmic Domain of the Platelet Glycoprotein Ibalpha Is Phosphorylated at Serine 609.

R. J. Bodnar, M. Gu, Z. Li, G. D. Englund, and X. Du (1999)
J. Biol. Chem. 274, 33474-33479
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Signaling Pathways of the Insulin-Like Growth Factor 1 Receptor in Protection from Apoptosis.

F. Peruzzi, M. Prisco, M. Dews, P. Salomoni, E. Grassilli, G. Romano, B. Calabretta, and R. Baserga (1999)
Mol. Cell. Biol. 19, 7203-7215
 |  Abstract »  |  Full Text »  |  PDF »

Association of the Ras to Mitogen-activated Protein Kinase Signal Transduction Pathway with Microfilaments. EVIDENCE FOR A p185neu-CONTAINING CELL SURFACE SIGNAL TRANSDUCTION PARTICLE LINKING THE MITOGENIC PATHWAY TO A MEMBRANE-MICROFILAMENT ASSOCIATION SITE.

C. A. C. Carraway, M. E. Carvajal, and K. L. Carraway (1999)
J. Biol. Chem. 274, 25659-25667
 |  Abstract »  |  Full Text »  |  PDF »

Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells.

J. C. Aliaga, C. Deschenes, J.-F. Beaulieu, E. L. Calvo, and N. Rivard (1999)
Am J Physiol Gastrointest Liver Physiol 277, G631-G641
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Localization of Protein Kinase U-alpha Is Regulated by 14-3-3.

S. Zhang, H. Xing, and A. J. Muslin (1999)
J. Biol. Chem. 274, 24865-24872
 |  Abstract »  |  Full Text »  |  PDF »

Specific Interactions with TBP and TFIIB in Vitro Suggest That 14-3-3 Proteins May Participate in the Regulation of Transcription When Part of a DNA Binding Complex.

S. Pan, P. C. Sehnke, R. J. Ferl, and W. B. Gurley (1999)
PLANT CELL 11, 1591-1602
 |  Abstract »  |  Full Text »

The Ankyrin Repeat-containing Adaptor Protein Tvl-1 Is a Novel Substrate and Regulator of Raf-1.

J.-H. Lin, A. Makris, C. McMahon, S. E. Bear, C. Patriotis, V. R. Prasad, R. Brent, E. A. Golemis, and P. N. Tsichlis (1999)
J. Biol. Chem. 274, 14706-14715
 |  Abstract »  |  Full Text »  |  PDF »

The zeta  Isoform of 14-3-3 Proteins Interacts with the Third Intracellular Loop of Different alpha 2-Adrenergic Receptor Subtypes.

L. Prezeau, J. G. Richman, S. W. Edwards, and L. E. Limbird (1999)
J. Biol. Chem. 274, 13462-13469
 |  Abstract »  |  Full Text »  |  PDF »

Cell Adhesion Regulates the Interaction between the Docking Protein p130Cas and the 14-3-3 Proteins.

M. Garcia-Guzman, F. Dolfi, M. Russello, and K. Vuori (1999)
J. Biol. Chem. 274, 5762-5768
 |  Abstract »  |  Full Text »  |  PDF »

Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human.

C. WIDMANN, S. GIBSON, M. B. JARPE, and G. L. JOHNSON (1999)
Physiol Rev 79, 143-180
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Ligand-binding Site in the zeta -Form 14-3-3 Protein Recognizing the Platelet Glycoprotein Ibalpha and Distinct from the c-Raf-binding Site.

M. Gu and X. Du (1998)
J. Biol. Chem. 273, 33465-33471
 |  Abstract »  |  Full Text »  |  PDF »

Hsp90 Is Required for Pheromone Signaling in Yeast.

J.-F. Louvion, T. Abbas-Terki, and D. Picard (1998)
Mol. Biol. Cell 9, 3071-3083
 |  Abstract »  |  Full Text »

Association of the TLX-2 Homeodomain and 14-3-3eta Signaling Proteins.

S. J. Tang, T.-C. Suen, R. R. McInnes, and M. Buchwald (1998)
J. Biol. Chem. 273, 25356-25363
 |  Abstract »  |  Full Text »  |  PDF »

Ras Isoforms Vary in Their Ability to Activate Raf-1 and Phosphoinositide 3-Kinase.

J. Yan, S. Roy, A. Apolloni, A. Lane, and J. F. Hancock (1998)
J. Biol. Chem. 273, 24052-24056
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 Proteins Are Required for Maintenance of Raf-1 Phosphorylation and Kinase Activity.

J. A. Thorson, L. W. K. Yu, A. L. Hsu, N.-Y. Shih, P. R. Graves, J. W. Tanner, P. M. Allen, H. Piwnica-Worms, and A. S. Shaw (1998)
Mol. Cell. Biol. 18, 5229-5238
 |  Abstract »  |  Full Text »

Identification of Residues in the Cysteine-rich Domain of Raf-1 That Control Ras Binding and Raf-1 Activity.

D. G. Winkler, R. E. Cutler Jr., J. K. Drugan, S. Campbell, D. K. Morrison, and J. A. Cooper (1998)
J. Biol. Chem. 273, 21578-21584
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 Facilitates Ras-Dependent Raf-1 Activation In Vitro and In Vivo.

S. Roy, R. A. McPherson, A. Apolloni, J. Yan, A. Lane, J. Clyde-Smith, and J. F. Hancock (1998)
Mol. Cell. Biol. 18, 3947-3955
 |  Abstract »  |  Full Text »

Mutations in the Hydrophobic Surface of an Amphipathic Groove of 14-3-3zeta Disrupt Its Interaction with Raf-1 Kinase.

H. Wang, L. Zhang, R. Liddington, and H. Fu (1998)
J. Biol. Chem. 273, 16297-16304
 |  Abstract »  |  Full Text »  |  PDF »

Association of the Arabidopsis CTR1 Raf-like kinase with the ETR1 and ERS ethylene receptors.

K. L. Clark, P. B. Larsen, X. Wang, and C. Chang (1998)
PNAS 95, 5401-5406
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 Proteins Interact with Specific MEK Kinases.

G. R. Fanger, C. Widmann, A. C. Porter, S. Sather, G. L. Johnson, and R. R. Vaillancourt (1998)
J. Biol. Chem. 273, 3476-3483
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Pathway by Conventional, Novel, and Atypical Protein Kinase C Isotypes.

D. C. Schönwasser, R. M. Marais, C. J. Marshall, and P. J. Parker (1998)
Mol. Cell. Biol. 18, 790-798
 |  Abstract »  |  Full Text »

Feedback Regulation of Raf-1 and Mitogen-activated Protein Kinase (MAP) Kinase Kinases 1 and 2 by MAP Kinase Phosphatase-1 (MKP-1).

P. S. Shapiro and N. G. Ahn (1998)
J. Biol. Chem. 273, 1788-1793
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3beta Protein Associates with Insulin Receptor Substrate 1 and Decreases Insulin-stimulated Phosphatidylinositol 3'-Kinase Activity in 3T3L1 Adipocytes.

A. Kosaki, K. Yamada, J. Suga, A. Otaka, and H. Kuzuya (1998)
J. Biol. Chem. 273, 940-944
 |  Abstract »  |  Full Text »  |  PDF »

Serine 257 Phosphorylation Regulates Association of Polyomavirus Middle T Antigen with 14-3-3 Proteins.

X. Cullere, P. Rose, U. Thathamangalam, A. Chatterjee, K. P. Mullane, D. C. Pallas, T. L. Benjamin, T. M. Roberts, and B. S. Schaffhausen (1998)
J. Virol. 72, 558-563
 |  Abstract »  |  Full Text »  |  PDF »

Interference of BAD (Bcl-xL/Bcl-2-Associated Death Promoter)-Induced Apoptosis in Mammalian Cells by 14-3-3 Isoforms and P11.

S. Y. Hsu, A. Kaipia, L. Zhu, and A. J. W. Hsueh (1997)
Mol. Endocrinol. 11, 1858-1867
 |  Abstract »  |  Full Text »

Serine Phosphorylation-dependent Association of the Band 4.1-related Protein-tyrosine Phosphatase PTPH1 with 14-3-3beta Protein.

S.-H. Zhang, R. Kobayashi, P. R. Graves, H. Piwnica-Worms, and N. K. Tonks (1997)
J. Biol. Chem. 272, 27281-27287
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of Phosphorylated Tryptophan Hydroxylase with 14-3-3 Proteins.

U. Banik, G.-A. Wang, P. D. Wagner, and S. Kaufman (1997)
J. Biol. Chem. 272, 26219-26225
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 Protein Binds to Insulin Receptor Substrate-1, One of the Binding Sites of Which Is in the Phosphotyrosine Binding Domain.

T. Ogihara, T. Isobe, T. Ichimura, M. Taoka, M. Funaki, H. Sakoda, Y. Onishi, K. Inukai, M. Anai, Y. Fukushima, et al. (1997)
J. Biol. Chem. 272, 25267-25274
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 zeta  Negatively Regulates Raf-1 Activity by Interactions with the Raf-1 Cysteine-rich Domain.

G. J. Clark, J. K. Drugan, K. L. Rossman, J. W. Carpenter, K. Rogers-Graham, H. Fu, C. J. Der, and S. L. Campbell (1997)
J. Biol. Chem. 272, 20990-20993
 |  Abstract »  |  Full Text »  |  PDF »

Activity of Plasma Membrane-recruited Raf-1 Is Regulated by Ras via the Raf Zinc Finger.

S. Roy, A. Lane, J. Yan, R. McPherson, and J. F. Hancock (1997)
J. Biol. Chem. 272, 20139-20145
 |  Abstract »  |  Full Text »  |  PDF »

Raf-1 Kinase and Exoenzyme S Interact with 14-3-3zeta through a Common Site Involving Lysine 49.

L. Zhang, H. Wang, D. Liu, R. Liddington, and H. Fu (1997)
J. Biol. Chem. 272, 13717-13724
 |  Abstract »  |  Full Text »  |  PDF »

Protein binding and signaling properties of RIN1 suggest a unique effector function.

L. Han, D. Wong, A. Dhaka, D. Afar, M. White, W. Xie, H. Herschman, O. Witte, and J. Colicelli (1997)
PNAS 94, 4954-4959
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila..

H C Chang and G M Rubin (1997)
Genes & Dev. 11, 1132-1139
 |  Abstract »  |  PDF »

Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor development..

L Kockel, G Vorbruggen, H Jackle, M Mlodzik, and D Bohmann (1997)
Genes & Dev. 11, 1140-1147
 |  Abstract »  |  PDF »

14-3-3 (epsilon ) Interacts with the Insulin-like Growth Factor I Receptor and Insulin Receptor Substrate I in a Phosphoserine-dependent Manner.

A. Craparo, R. Freund, and T. A. Gustafson (1997)
J. Biol. Chem. 272, 11663-11669
 |  Abstract »  |  Full Text »  |  PDF »

Serine Phosphorylation of Cbl Induced by Phorbol Ester Enhances Its Association with 14-3-3Proteins in T Cells via a Novel Serine-rich 14-3-3-binding Motif.

Y.-C. Liu, Y. Liu, C. Elly, H. Yoshida, S. Lipkowitz, and A. Altman (1997)
J. Biol. Chem. 272, 9979-9985
 |  Abstract »  |  Full Text »  |  PDF »

Negative Modulation of Membrane Localization of the Raf-1 Protein Kinase by Hyperphosphorylation.

M. Wartmann, P. Hofer, P. Turowski, A. R. Saltiel, and N. E. Hynes (1997)
J. Biol. Chem. 272, 3915-3923
 |  Abstract »  |  Full Text »  |  PDF »

The Drosophila 14-3-3 protein Leonardo enhances Torso signaling through D-Raf in a Ras 1-dependent manner.

W Li, E. Skoulakis, R. Davis, and N Perrimon (1997)
Development 124, 4163-4171
 |  Abstract »  |  PDF »

The 14-3-3 Brain Protein in Cerebrospinal Fluid as a Marker for Transmissible Spongiform Encephalopathies.

G. Hsich, K. Kenney, C. J. Gibbs, K. H. Lee, and M. G. Harrington (1996)
N. Engl. J. Med. 335, 924-930
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3 Proteins Associate with A20 in an Isoform-specific Manner and Function Both as Chaperone and Adapter Molecules.

C. Vincenz and V. M. Dixit (1996)
J. Biol. Chem. 271, 20029-20034
 |  Abstract »  |  Full Text »  |  PDF »

Activation-modulated Association of 14-3-3Proteins with Cbl in T Cells.

Y.-C. Liu, C. Elly, H. Yoshida, N. Bonnefoy-Berard, and A. Altman (1996)
J. Biol. Chem. 271, 14591-14595
 |  Abstract »  |  Full Text »  |  PDF »

PKN Associates and Phosphorylates the Head-Rod Domain of Neurofilament Protein.

H. Mukai, M. Toshimori, H. Shibata, M. Kitagawa, M. Shimakawa, M. Miyahara, H. Sunakawa, and Y. Ono (1996)
J. Biol. Chem. 271, 9816-9822
 |  Abstract »  |  Full Text »  |  PDF »

Raf-1 Kinase Possesses Distinct Binding Domains for Phosphatidylserine and Phosphatidic Acid.

S. Ghosh, J. C. Strum, V. A. Sciorra, L. Daniel, and R. M. Bell (1996)
J. Biol. Chem. 271, 8472-8480
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Binding Sequence for the 14-3-3 Protein within the Cytoplasmic Domain of the Adhesion Receptor, Platelet Glycoprotein Ibalpha.

X. Du, J. E. Fox, and S. Pei (1996)
J. Biol. Chem. 271, 7362-7367
 |  Abstract »  |  Full Text »  |  PDF »

Ras Interaction with Two Distinct Binding Domains in Raf-1 May Be Required for Ras Transformation.

J. K. Drugan, R. Khosravi-Far, M. A. White, C. J. Der, Y.-J. Sung, Y.-W. Hwang, and S. L. Campbell (1996)
J. Biol. Chem. 271, 233-237
 |  Abstract »  |  Full Text »  |  PDF »

Identification of the 14.3.3 [IMAGE] Domains Important for Self-association and Raf Binding.

Z.-j. Luo, X.-f. Zhang, U. Rapp, and J. Avruch (1995)
J. Biol. Chem. 270, 23681-23687
 |  Abstract »  |  Full Text »  |  PDF »

Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases.

P Dent, T Jelinek, D. Morrison, M. Weber, and T. Sturgill (1995)
Science 268, 1902-1906
 |  Abstract »  |  PDF »

A Direct Interaction between G-Protein [IMAGE][IMAGE] Subunits and the Raf-1 Protein Kinase.

K. M. Pumiglia, H. LeVine, T. Haske, T. Habib, R. Jove, and S. J. Decker (1995)
J. Biol. Chem. 270, 14251-14254
 |  Abstract »  |  Full Text »  |  PDF »

Purification of a Ras-dependent Mitogen-activated Protein Kinase Kinase Kinase from Bovine Brain Cytosol and Its Identification as a Complex of B-Raf and 14-3-3 Proteins.

B. Yamamori, S. Kuroda, K. Shimizu, K. Fukui, T. Ohtsuka, and Y. Takai (1995)
J. Biol. Chem. 270, 11723-11726
 |  Abstract »  |  Full Text »  |  PDF »

Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation..

K Galaktionov, C Jessus, and D Beach (1995)
Genes & Dev. 9, 1046-1058
 |  Abstract »  |  PDF »

Localization of protein kinases by anchoring proteins: a theme in signal transduction.

D Mochly-Rosen (1995)
Science 268, 247-251
 |  Abstract »  |  PDF »

14-3-3 alpha and [IMAGE] Are the Phosphorylated Forms of Raf-activating 14-3-3 beta and [IMAGE].

A. Aitken, S. Howell, D. Jones, J. Madrazo, and Y. Patel (1995)
J. Biol. Chem. 270, 5706-5709
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Activation of Mitogen-activated Protein Kinase by Arachidonic Acid in Rat Liver Epithelial WB Cells by a Protein Kinase C-dependent Mechanism.

C. S. T. Hii, A. Ferrante, Y. S. Edwards, Z. H. Huang, P. J. Hartfield, D. A. Rathjen, A. Poulos, and A. W. Murray (1995)
J. Biol. Chem. 270, 4201-4204
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A Constitutive Effector Region on the C-terminal Side of Switch I of the Ras Protein.

J. Fujita-Yoshigaki, M. Shirouzu, Y. Ito, S. Hattori, S. Furuyama, S. Nishimura, and S. Yokoyama (1995)
J. Biol. Chem. 270, 4661-4667
 |  Abstract »  |  Full Text »  |  PDF »

Stratifin, a keratinocyte specific 14-3-3 protein, harbors a pleckstrin homology (PH) domain and enhances protein kinase C activity.

E Dellambra, M Patrone, B Sparatore, A Negri, F Ceciliani, S Bondanza, F Molina, F. Cancedda, and M De Luca (1995)
J. Cell Sci. 108, 3569-3579
 |  Abstract »  |  PDF »

14-3-3: modulators of signaling proteins?.

D Morrison (1994)
Science 266, 56-57
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Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase.

K Irie, Y Gotoh, B. Yashar, B Errede, E Nishida, and K Matsumoto (1994)
Science 265, 1716-1719
 |  Abstract »  |  PDF »

Proteins of the 14-3-3 Family Associate with Raf and Contribute to Its Activation.

E. Freed, F. McCormick, and R. Ruggieri (1994)
Cold Spring Harb Symp Quant Biol 59, 187-193
 |  Abstract »  |  PDF »

Calyculin A-induced Vimentin Phosphorylation Sequesters 14-3-3 and Displaces Other 14-3-3 Partners in Vivo.

G. Tzivion, Z.-J. Luo, and J. Avruch (2000)
J. Biol. Chem. 275, 29772-29778
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The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras.

M. A. Rizzo, K. Shome, S. C. Watkins, and G. Romero (2000)
J. Biol. Chem. 275, 23911-23918
 |  Abstract »  |  Full Text »  |  PDF »

14-3-3zeta Is an Effector of Tau Protein Phosphorylation.

M. Hashiguchi, K. Sobue, and H. K. Paudel (2000)
J. Biol. Chem. 275, 25247-25254
 |  Abstract »  |  Full Text »  |  PDF »

Signal Transduction by the CEACAM1 Tumor Suppressor. PHOSPHORYLATION OF SERINE 503 IS REQUIRED FOR GROWTH-INHIBITORY ACTIVITY.

V. T. Estrera, D.-T. Chen, W. Luo, D. C. Hixson, and S.-H. Lin (2001)
J. Biol. Chem. 276, 15547-15553
 |  Abstract »  |  Full Text »  |  PDF »

Anti-apoptotic Signaling of the Insulin-like Growth Factor-I Receptor through Mitochondrial Translocation of c-Raf and Nedd4.

F. Peruzzi, M. Prisco, A. Morrione, B. Valentinis, and R. Baserga (2001)
J. Biol. Chem. 276, 25990-25996
 |  Abstract »  |  Full Text »  |  PDF »

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