Science 16 September 1994: Vol. 265. no. 5179, pp. 1706 - 1709 DOI: 10.1126/science.8085156

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Articles

CDKL5 influences RNA splicing activity by its association to the nuclear speckle molecular machinery.

S. Ricciardi, C. Kilstrup-Nielsen, T. Bienvenu, A. Jacquette, N. Landsberger, and V. Broccoli (2009)
Hum. Mol. Genet. 18, 4590-4602
 |  Abstract »  |  Full Text »  |  PDF »

Functional properties and evolutionary splicing constraints on a composite exonic regulatory element of splicing in CFTR exon 12.

A. Haque, E. Buratti, and F. E. Baralle (2009)
Nucleic Acids Res.
 |  Abstract »  |  Full Text »  |  PDF »

Proteomic Analysis of Phosphorylated Nuclear Proteins Underscores Novel Roles for Rapid Actions of Retinoic Acid in the Regulation of mRNA Splicing and Translation.

E. J. Laserna, M. L. Valero, L. Sanz, M. M. Sanchez del Pino, J. J. Calvete, and D. Barettino (2009)
Mol. Endocrinol. 23, 1799-1814
 |  Abstract »  |  Full Text »  |  PDF »

Blom7{alpha} Is a Novel Heterogeneous Nuclear Ribonucleoprotein K Homology Domain Protein Involved in Pre-mRNA Splicing That Interacts with SNEVPrp19-Pso4.

J. Grillari, M. Loscher, M. Denegri, K. Lee, K. Fortschegger, F. Eisenhaber, P. Ajuh, A. I. Lamond, H. Katinger, and R. Grillari-Voglauer (2009)
J. Biol. Chem. 284, 29193-29204
 |  Abstract »  |  Full Text »  |  PDF »

Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease.

A. Belfiore, F. Frasca, G. Pandini, L. Sciacca, and R. Vigneri (2009)
Endocr. Rev. 30, 586-623
 |  Abstract »  |  Full Text »  |  PDF »

Auto- and Cross-Regulation of the hnRNP L Proteins by Alternative Splicing.

O. Rossbach, L.-H. Hung, S. Schreiner, I. Grishina, M. Heiner, J. Hui, and A. Bindereif (2009)
Mol. Cell. Biol. 29, 1442-1451
 |  Abstract »  |  Full Text »  |  PDF »

Spatial mapping of splicing factor complexes involved in exon and intron definition.

J. D. Ellis, D. Lleres, M. Denegri, A. I. Lamond, and J. F. Caceres (2008)
J. Cell Biol. 181, 921-934
 |  Abstract »  |  Full Text »  |  PDF »

Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.

S. Ahmed, H. Marotte, K. Kwan, J. H. Ruth, P. L. Campbell, B. J. Rabquer, A. Pakozdi, and A. E. Koch (2008)
PNAS 105, 14692-14697
 |  Abstract »  |  Full Text »  |  PDF »

Epstein-Barr Virus SM Protein Functions as an Alternative Splicing Factor.

D. Verma and S. Swaminathan (2008)
J. Virol. 82, 7180-7188
 |  Abstract »  |  Full Text »  |  PDF »

Multifactorial Interplay Controls the Splicing Profile of Alu-Derived Exons.

O. Ram, S. Schwartz, and G. Ast (2008)
Mol. Cell. Biol. 28, 3513-3525
 |  Abstract »  |  Full Text »  |  PDF »

Combination of Clk family kinase and SRp75 modulates alternative splicing of Adenovirus E1A..

J.-i. Yomoda, M. Muraki, N. Kataoka, T. Hosoya, M. Suzuki, M. Hagiwara, and H. Kimura (2008)
Genes Cells 13, 233-244
 |  Abstract »  |  Full Text »  |  PDF »

Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics.

X. Roca, A. J. Olson, A. R. Rao, E. Enerly, V. N. Kristensen, A.-L. Borresen-Dale, B. S. Andresen, A. R. Krainer, and R. Sachidanandam (2008)
Genome Res. 18, 77-87
 |  Abstract »  |  Full Text »  |  PDF »

The Transcription-Dependent Dissociation of P-TEFb-HEXIM1-7SK RNA Relies upon Formation of hnRNP-7SK RNA Complexes.

C. Barrandon, F. Bonnet, V. T. Nguyen, V. Labas, and O. Bensaude (2007)
Mol. Cell. Biol. 27, 6996-7006
 |  Abstract »  |  Full Text »  |  PDF »

HMGA1a: sequence-specific RNA-binding factor causing sporadic Alzheimer's disease-linked exon skipping of presenilin-2 pre-mRNA.

T. Manabe, K. Ohe, T. Katayama, S. Matsuzaki, T. Yanagita, H. Okuda, Y. Bando, K. Imaizumi, R. Reeves, M. Tohyama, et al. (2007)
Genes Cells 12, 1179-1191
 |  Abstract »  |  Full Text »  |  PDF »

The U1 snRNP-associated factor Luc7p affects 5' splice site selection in yeast and human.

O. Puig, E. Bragado-Nilsson, T. Koski, and B. Seraphin (2007)
Nucleic Acids Res. 35, 5874-5885
 |  Abstract »  |  Full Text »  |  PDF »

Members of the Heterogeneous Nuclear Ribonucleoprotein H Family Activate Splicing of an HIV-1 Splicing Substrate by Promoting Formation of ATP-dependent Spliceosomal Complexes.

M. C. Schaub, S. R. Lopez, and M. Caputi (2007)
J. Biol. Chem. 282, 13617-13626
 |  Abstract »  |  Full Text »  |  PDF »

Regulated nucleo-cytoplasmic shuttling of human aci-reductone dioxygenase (hADI1) and its potential role in mRNA processing..

I. Gotoh, T. Uekita, and M. Seiki (2007)
Genes Cells 12, 105-117
 |  Abstract »  |  Full Text »  |  PDF »

Concentration dependent selection of targets by an SR splicing regulator results in tissue-specific RNA processing.

J. Qi, S. Su, M. E. McGuffin, and W. Mattox (2006)
Nucleic Acids Res. 34, 6256-6263
 |  Abstract »  |  Full Text »  |  PDF »

Activation of {alpha}-Tropomyosin Exon 2 Is Regulated by the SR Protein 9G8 and Heterogeneous Nuclear Ribonucleoproteins H and F.

J. B. Crawford and J. G. Patton (2006)
Mol. Cell. Biol. 26, 8791-8802
 |  Abstract »  |  Full Text »  |  PDF »

Human sat III and Drosophila hsr{omega} transcripts: a common paradigm for regulation of nuclear RNA processing in stressed cells.

C. Jolly and S. C. Lakhotia (2006)
Nucleic Acids Res. 34, 5508-5514
 |  Abstract »  |  Full Text »  |  PDF »

hnRNP A1 Relocalization to the Stress Granules Reflects a Role in the Stress Response.

S. Guil, J. C. Long, and J. F. Caceres (2006)
Mol. Cell. Biol. 26, 5744-5758
 |  Abstract »  |  Full Text »  |  PDF »

Alternative splicing factor ASF/SF2 is down regulated in inflamed muscle.

Z Xiong, A Shaibani, Y-P Li, Y Yan, S Zhang, Y Yang, F Yang, H Wang, and X-F Yang (2006)
J. Clin. Pathol. 59, 855-861
 |  Abstract »  |  Full Text »  |  PDF »

Defective splicing, disease and therapy: searching for master checkpoints in exon definition.

E. Buratti, M. Baralle, and F. E. Baralle (2006)
Nucleic Acids Res. 34, 3494-3510
 |  Abstract »  |  Full Text »  |  PDF »

Spi-1/PU.1 Oncoprotein Affects Splicing Decisions in a Promoter Binding-dependent Manner.

C. Guillouf, I. Gallais, and F. Moreau-Gachelin (2006)
J. Biol. Chem. 281, 19145-19155
 |  Abstract »  |  Full Text »  |  PDF »

Cryptic splice site usage in exon 7 of the human fibrinogen B{beta}-chain gene is regulated by a naturally silent SF2/ASF binding site within this exon.

S. Spena, M. L. Tenchini, and E. Buratti (2006)
RNA 12, 948-958
 |  Abstract »  |  Full Text »  |  PDF »

Exon Selection in {alpha}-Tropomyosin mRNA Is Regulated by the Antagonistic Action of RBM4 and PTB.

J.-C. Lin and W.-Y. Tarn (2005)
Mol. Cell. Biol. 25, 10111-10121
 |  Abstract »  |  Full Text »  |  PDF »

TDP-43 Binds Heterogeneous Nuclear Ribonucleoprotein A/B through Its C-terminal Tail: AN IMPORTANT REGION FOR THE INHIBITION OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR EXON 9 SPLICING.

E. Buratti, A. Brindisi, M. Giombi, S. Tisminetzky, Y. M. Ayala, and F. E. Baralle (2005)
J. Biol. Chem. 280, 37572-37584
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of the Epstein-Barr Virus mRNA Export Factor EB2 with Human Spen Proteins SHARP, OTT1, and a Novel Member of the Family, OTT3, Links Spen Proteins with Splicing Regulation and mRNA Export.

E. Hiriart, H. Gruffat, M. Buisson, I. Mikaelian, S. Keppler, P. Meresse, T. Mercher, O. A. Bernard, A. Sergeant, and E. Manet (2005)
J. Biol. Chem. 280, 36935-36945
 |  Abstract »  |  Full Text »  |  PDF »

The Switch in Alternative Splicing of Cyclic AMP-response Element Modulator Protein CREM{tau}2{alpha} (Activator) to CREM{alpha} (Repressor) in Human Myometrial Cells Is Mediated by SRp40.

A. J. Tyson-Capper, J. Bailey, A. R. Krainer, S. C. Robson, and G. N. Europe-Finner (2005)
J. Biol. Chem. 280, 34521-34529
 |  Abstract »  |  Full Text »  |  PDF »

The Oncogenic TLS-ERG Fusion Protein Exerts Different Effects in Hematopoietic Cells and Fibroblasts.

J. Zou, H. Ichikawa, M. L. Blackburn, H.-M. Hu, A. Zielinska-Kwiatkowska, Q. Mei, G. J. Roth, H. A. Chansky, and L. Yang (2005)
Mol. Cell. Biol. 25, 6235-6246
 |  Abstract »  |  Full Text »  |  PDF »

Exonization of AluYa5 in the human ACE gene requires mutations in both 3' and 5' splice sites and is facilitated by a conserved splicing enhancer.

H. Lei, I. N. M. Day, and I. Vorechovsky (2005)
Nucleic Acids Res. 33, 3897-3906
 |  Abstract »  |  Full Text »  |  PDF »

Global analysis of positive and negative pre-mRNA splicing regulators in Drosophila.

M. Blanchette, R. E. Green, S. E. Brenner, and D. C. Rio (2005)
Genes & Dev. 19, 1306-1314
 |  Abstract »  |  Full Text »  |  PDF »

Determinants of the inherent strength of human 5' splice sites.

X. ROCA, R. SACHIDANANDAM, and A. R. KRAINER (2005)
RNA 11, 683-698
 |  Abstract »  |  Full Text »  |  PDF »

A Novel SR-Related Protein Is Required for the Second Step of Pre-mRNA Splicing.

D. Cazalla, K. Newton, and J. F. Caceres (2005)
Mol. Cell. Biol. 25, 2969-2980
 |  Abstract »  |  Full Text »  |  PDF »

Molecular and Genetic Studies Imply Akt-mediated Signaling Promotes Protein Kinase C{beta}II Alternative Splicing via Phosphorylation of Serine/Arginine-rich Splicing Factor SRp40.

N. A. Patel, S. Kaneko, H. S. Apostolatos, S. S. Bae, J. E. Watson, K. Davidowitz, D. S. Chappell, M. J. Birnbaum, J. Q. Cheng, and D. R. Cooper (2005)
J. Biol. Chem. 280, 14302-14309
 |  Abstract »  |  Full Text »  |  PDF »

Hrp59, an hnRNP M protein in Chironomus and Drosophila, binds to exonic splicing enhancers and is required for expression of a subset of mRNAs.

E. Kiesler, M. E. Hase, D. Brodin, and N. Visa (2005)
J. Cell Biol. 168, 1013-1025
 |  Abstract »  |  Full Text »  |  PDF »

An erythroid differentiation-specific splicing switch in protein 4.1R mediated by the interaction of SF2/ASF with an exonic splicing enhancer.

G. Yang, S.-C. Huang, J. Y. Wu, and E. J. Benz Jr (2005)
Blood 105, 2146-2153
 |  Abstract »  |  Full Text »  |  PDF »

Branch site haplotypes that control alternative splicing.

J. Kralovicova, S. Houngninou-Molango, A. Kramer, and I. Vorechovsky (2004)
Hum. Mol. Genet. 13, 3189-3202
 |  Abstract »  |  Full Text »  |  PDF »

The WW Domain-Containing Proteins Interact with the Early Spliceosome and Participate in Pre-mRNA Splicing In Vivo.

K.-T. Lin, R.-M. Lu, and W.-Y. Tarn (2004)
Mol. Cell. Biol. 24, 9176-9185
 |  Abstract »  |  Full Text »  |  PDF »

SF2/ASF Binds the Human Papillomavirus Type 16 Late RNA Control Element and Is Regulated during Differentiation of Virus-Infected Epithelial Cells.

M. G. McPhillips, T. Veerapraditsin, S. A. Cumming, D. Karali, S. G. Milligan, W. Boner, I. M. Morgan, and S. V. Graham (2004)
J. Virol. 78, 10598-10605
 |  Abstract »  |  Full Text »  |  PDF »

Genome-wide analysis of alternative pre-mRNA splicing in Arabidopsis thaliana based on full-length cDNA sequences.

K. Iida, M. Seki, T. Sakurai, M. Satou, K. Akiyama, T. Toyoda, A. Konagaya, and K. Shinozaki (2004)
Nucleic Acids Res. 32, 5096-5103
 |  Abstract »  |  Full Text »  |  PDF »

RNA recognition motif 2 directs the recruitment of SF2/ASF to nuclear stress bodies.

I. Chiodi, M. Corioni, M. Giordano, R. Valgardsdottir, C. Ghigna, F. Cobianchi, R.-M. Xu, S. Riva, and G. Biamonti (2004)
Nucleic Acids Res. 32, 4127-4136
 |  Abstract »  |  Full Text »  |  PDF »

Manipulation of Alternative Splicing by a Newly Developed Inhibitor of Clks.

M. Muraki, B. Ohkawara, T. Hosoya, H. Onogi, J. Koizumi, T. Koizumi, K. Sumi, J.-i. Yomoda, M. V. Murray, H. Kimura, et al. (2004)
J. Biol. Chem. 279, 24246-24254
 |  Abstract »  |  Full Text »  |  PDF »

Polypyrimidine Tract-binding Protein Is Involved in Vivo in Repression of a Composite Internal/3' -Terminal Exon of the Xenopus {alpha}-Tropomyosin Pre-mRNA.

S. Hamon, C. Le Sommer, A. Mereau, M.-R. Allo, and S. Hardy (2004)
J. Biol. Chem. 279, 22166-22175
 |  Abstract »  |  Full Text »  |  PDF »

A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2.

H. SHEN, J. L.C. KAN, C. GHIGNA, G. BIAMONTI, and M. R. GREEN (2004)
RNA 10, 787-794
 |  Abstract »  |  Full Text »  |  PDF »

Insulin Regulates Protein Kinase C{beta}II Alternative Splicing in Multiple Target Tissues: Development of a Hormonally Responsive Heterologous Minigene.

N. A. Patel, H. S. Apostolatos, K. Mebert, C. E. Chalfant, J. E. Watson, T. S. Pillay, J. Sparks, and D. R. Cooper (2004)
Mol. Endocrinol. 18, 899-911
 |  Abstract »  |  Full Text »  |  PDF »

A novel role for shuttling SR proteins in mRNA translation.

J. R. Sanford, N. K. Gray, K. Beckmann, and J. F. Caceres (2004)
Genes & Dev. 18, 755-768
 |  Abstract »  |  Full Text »  |  PDF »

An Intronic Enhancer Regulates Splicing of the Twintron of Drosophila melanogaster prospero Pre-mRNA by Two Different Spliceosomes.

P. Scamborova, A. Wong, and J. A. Steitz (2004)
Mol. Cell. Biol. 24, 1855-1869
 |  Abstract »  |  Full Text »  |  PDF »

Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA.

P. Stoilov, R. Daoud, O. Nayler, and S. Stamm (2004)
Hum. Mol. Genet. 13, 509-524
 |  Abstract »  |  Full Text »  |  PDF »

Rescue of a human mRNA splicing defect by the plant cytokinin kinetin.

S. A. Slaugenhaupt, J. Mull, M. Leyne, M. P. Cuajungco, S. P. Gill, M. M. Hims, F. Quintero, F. B. Axelrod, and J. F. Gusella (2004)
Hum. Mol. Genet. 13, 429-436
 |  Abstract »  |  Full Text »  |  PDF »

Human RNPS1 and Its Associated Factors: a Versatile Alternative Pre-mRNA Splicing Regulator In Vivo.

E. Sakashita, S. Tatsumi, D. Werner, H. Endo, and A. Mayeda (2004)
Mol. Cell. Biol. 24, 1174-1187
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Alternative Splicing by SRrp86 and Its Interacting Proteins.

J. Li, I. C. Hawkins, C. D. Harvey, J. L. Jennings, A. J. Link, and J. G. Patton (2003)
Mol. Cell. Biol. 23, 7437-7447
 |  Abstract »  |  Full Text »  |  PDF »

Intrinsic differences between authentic and cryptic 5' splice sites.

X. Roca, R. Sachidanandam, and A. R. Krainer (2003)
Nucleic Acids Res. 31, 6321-6333
 |  Abstract »  |  Full Text »  |  PDF »

Pinin/DRS/memA Interacts with SRp75, SRm300 and SRrp130 in Corneal Epithelial Cells.

G. Zimowska, J. Shi, G. Munguba, M. R. Jackson, R. Alpatov, M. N. Simmons, Y. Shi, and S. P. Sugrue (2003)
Invest. Ophthalmol. Vis. Sci. 44, 4715-4723
 |  Abstract »  |  Full Text »  |  PDF »

Monochloramine induces reorganization of nuclear speckles and phosphorylation of SRp30 in human colonic epithelial cells: role of protein kinase C.

Y.-Q. Zhu, Y. Lu, and X.-D. Tan (2003)
Am J Physiol Cell Physiol 285, C1294-C1303
 |  Abstract »  |  Full Text »  |  PDF »

B-cell and plasma-cell splicing differences: A potential role in regulated immunoglobulin RNA processing.

S. R. BRUCE, R.W. C. DINGLE, and M. L. PETERSON (2003)
RNA 9, 1264-1273
 |  Abstract »  |  Full Text »  |  PDF »

Complementary DNA macroarray analyses of differential gene expression in porcine fetal and postnatal muscle.

S.-H. Zhao, D. Nettleton, W. Liu, C. Fitzsimmons, C.W. Ernst, N. E. Raney, and C. K. Tuggle (2003)
J Anim Sci 81, 2179-2188
 |  Abstract »  |  Full Text »  |  PDF »

Missense, Nonsense, and Neutral Mutations Define Juxtaposed Regulatory Elements of Splicing in Cystic Fibrosis Transmembrane Regulator Exon 9.

F. Pagani, E. Buratti, C. Stuani, and F. E. Baralle (2003)
J. Biol. Chem. 278, 26580-26588
 |  Abstract »  |  Full Text »  |  PDF »

New type of disease causing mutations: the example of the composite exonic regulatory elements of splicing in CFTR exon 12.

F. Pagani, C. Stuani, M. Tzetis, E. Kanavakis, A. Efthymiadou, S. Doudounakis, T. Casals, and F. E. Baralle (2003)
Hum. Mol. Genet. 12, 1111-1120
 |  Abstract »  |  Full Text »  |  PDF »

Splicing Factor SRp30c Interaction with Y-box Protein-1 Confers Nuclear YB-1 Shuttling and Alternative Splice Site Selection.

U. Raffetseder, B. Frye, T. Rauen, K. Jurchott, H.-D. Royer, P. L. Jansen, and P. R. Mertens (2003)
J. Biol. Chem. 278, 18241-18248
 |  Abstract »  |  Full Text »  |  PDF »

Roles of hnRNP A1, SR Proteins, and p68 Helicase in c-H-ras Alternative Splicing Regulation.

S. Guil, R. Gattoni, M. Carrascal, J. Abian, J. Stevenin, and M. Bach-Elias (2003)
Mol. Cell. Biol. 23, 2927-2941
 |  Abstract »  |  Full Text »  |  PDF »

Antagonistic regulation of {alpha}-actinin alternative splicing by CELF proteins and polypyrimidine tract binding protein.

N. GROMAK, A. J. MATLIN, T. A. COOPER, and C. W.J. SMITH (2003)
RNA 9, 443-456
 |  Abstract »  |  Full Text »  |  PDF »

Roles for SR Proteins and hnRNP A1 in the Regulation of c-src Exon N1.

N. Rooke, V. Markovtsov, E. Cagavi, and D. L. Black (2003)
Mol. Cell. Biol. 23, 1874-1884
 |  Abstract »  |  Full Text »  |  PDF »

Promoter Architecture Modulates CFTR Exon 9 Skipping.

F. Pagani, C. Stuani, E. Zuccato, A. R. Kornblihtt, and F. E. Baralle (2003)
J. Biol. Chem. 278, 1511-1517
 |  Abstract »  |  Full Text »  |  PDF »

A Non-sequence-specific Double-stranded RNA Structural Element Regulates Splicing of Two Mutually Exclusive Exons of Fibroblast Growth Factor Receptor 2 (FGFR2).

S. J. Muh, R. H. Hovhannisyan, and R. P. Carstens (2002)
J. Biol. Chem. 277, 50143-50154
 |  Abstract »  |  Full Text »  |  PDF »

Human Autoimmune Sera as Molecular Probes for the Identification of an Autoantigen Kinase Signaling Pathway.

M. Kamachi, T. M. Le, S. J. Kim, M. E. Geiger, P. Anderson, and P. J. Utz (2002)
J. Exp. Med. 196, 1213-1226
 |  Abstract »  |  Full Text »  |  PDF »

Temperature-dependent splicing of {beta}-globin pre-mRNA.

F. Gemignani, P. Sazani, P. Morcos, and R. Kole (2002)
Nucleic Acids Res. 30, 4592-4598
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Export and Retention Signals in the RS Domain of SR Proteins.

D. Cazalla, J. Zhu, L. Manche, E. Huber, A. R. Krainer, and J. F. Caceres (2002)
Mol. Cell. Biol. 22, 6871-6882
 |  Abstract »  |  Full Text »  |  PDF »

Ischemia Induces a Translocation of the Splicing Factor tra2-beta 1 and Changes Alternative Splicing Patterns in the Brain.

R. Daoud, G. Mies, A. Smialowska, L. Olah, K.-A. Hossmann, and S. Stamm (2002)
J. Neurosci. 22, 5889-5899
 |  Abstract »  |  Full Text »  |  PDF »

Alternative Splice Variants of Doublecortin-like Kinase Are Differentially Expressed and Have Different Kinase Activities.

H. A. Burgess and O. Reiner (2002)
J. Biol. Chem. 277, 17696-17705
 |  Abstract »  |  Full Text »  |  PDF »

Alternative Splicing of the Adenylyl Cyclase Stimulatory G-protein Galpha s Is Regulated by SF2/ASF and Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNPA1) and Involves the Use of an Unusual TG 3'-Splice Site.

A. J. Pollard, A. R. Krainer, S. C. Robson, and G. N. Europe-Finner (2002)
J. Biol. Chem. 277, 15241-15251
 |  Abstract »  |  Full Text »  |  PDF »

Positive and Negative Modulation of Human Immunodeficiency Virus Type 1 Rev Function by cis and trans Regulators of Viral RNA Splicing.

J. Pongoski, K. Asai, and A. Cochrane (2002)
J. Virol. 76, 5108-5120
 |  Abstract »  |  Full Text »  |  PDF »

Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1.

J. Vitali, J. Ding, J. Jiang, Y. Zhang, A. R. Krainer, and R.-M. Xu (2002)
Nucleic Acids Res. 30, 1531-1538
 |  Abstract »  |  Full Text »  |  PDF »

An Exonic Splicing Enhancer in Human IGF-I Pre-mRNA Mediates Recognition of Alternative Exon 5 by the Serine-Arginine Protein Splicing Factor-2/ Alternative Splicing Factor.

P. J. Smith, E. L. Spurrell, J. Coakley, C. J. Hinds, R. J. M. Ross, A. R. Krainer, and S. L. Chew (2002)
Endocrinology 143, 146-154
 |  Abstract »  |  Full Text »  |  PDF »

Multiple cis elements regulate an alternative splicing event at 4.1R pre-mRNA during erythroid differentiation.

M. Deguillien, S.-C. Huang, M. Moriniere, N. Dreumont, E. J. Benz Jr, and F. Baklouti (2001)
Blood 98, 3809-3816
 |  Abstract »  |  Full Text »  |  PDF »

Correction of Alternative Splicing of Tau in Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17.

B. Kalbfuss, S. A. Mabon, and T. Misteli (2001)
J. Biol. Chem. 276, 42986-42993
 |  Abstract »  |  Full Text »  |  PDF »

Stress-induced Nuclear Bodies Are Sites of Accumulation of Pre-mRNA Processing Factors.

M. Denegri, I. Chiodi, M. Corioni, F. Cobianchi, S. Riva, and G. Biamonti (2001)
Mol. Biol. Cell 12, 3502-3514
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Characterization of an Alternatively Spliced Form of SR Protein Kinase 1 That Interacts Specifically with Scaffold Attachment Factor-B.

E. Nikolakaki, R. Kohen, A. M. Hartmann, S. Stamm, E. Georgatsou, and T. Giannakouros (2001)
J. Biol. Chem. 276, 40175-40182
 |  Abstract »  |  Full Text »  |  PDF »

5'- and 3'-terminal nucleotides in the FGFR2 ISAR splicing element core have overlapping roles in exon IIIb activation and exon IIIc repression.

R. B. Jones, R. P. Carstens, Y. Luo, and W. L. McKeehan (2001)
Nucleic Acids Res. 29, 3557-3565
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of SR protein localization during development.

J. R. Sanford and J. P. Bruzik (2001)
PNAS 98, 10184-10189
 |  Abstract »  |  Full Text »  |  PDF »

Treatment of spinal muscular atrophy by sodium butyrate.

J.-G. Chang, H.-M. Hsieh-Li, Y.-J. Jong, N. M. Wang, C.-H. Tsai, and H. Li (2001)
PNAS 98, 9808-9813
 |  Abstract »  |  Full Text »  |  PDF »

ZNF265--a novel spliceosomal protein able to induce alternative splicing.

D. J. Adams, L. van der Weyden, A. Mayeda, S. Stamm, B. J. Morris, and J. E.J. Rasko (2001)
J. Cell Biol. 154, 25-32
 |  Abstract »  |  Full Text »  |  PDF »

Human GC-AG alternative intron isoforms with weak donor sites show enhanced consensus at acceptor exon positions.

T. A. Thanaraj and F. Clark (2001)
Nucleic Acids Res. 29, 2581-2593
 |  Abstract »  |  Full Text »  |  PDF »

Polypyrimidine Tract Binding Protein Antagonizes Exon Definition.

E. J. Wagner and M. A. Garcia-Blanco (2001)
Mol. Cell. Biol. 21, 3281-3288
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Interaction between hnRNPA1 and I{kappa}B{alpha} Is Required for Maximal Activation of NF-{kappa}B-Dependent Transcription.

D. C. Hay, G. D. Kemp, C. Dargemont, and R. T. Hay (2001)
Mol. Cell. Biol. 21, 3482-3490
 |  Abstract »  |  Full Text »

An Intronic Splicing Enhancer Binds U1 snRNPs To Enhance Splicing and Select 5' Splice Sites.

A. J. McCullough and S. M. Berget (2000)
Mol. Cell. Biol. 20, 9225-9235
 |  Abstract »  |  Full Text »

Role of SR protein modular domains in alternative splicing specificity in vivo.

W. van der Houven van Oordt, K. Newton, G. R. Screaton, and J. F. Caceres (2000)
Nucleic Acids Res. 28, 4822-4831
 |  Abstract »  |  Full Text »  |  PDF »

Uterine expression of alternatively spliced mRNAs of mouse splicing factor SC35 during early pregnancy.

G.-Y. Nie, Y. Li, L. Batten, B. Griffiths, J. Wang, J. K. Findlay, and L. A. Salamonsen (2000)
Mol. Hum. Reprod. 6, 1131-1139
 |  Abstract »  |  Full Text »  |  PDF »

Selection of Alternative 5' Splice Sites: Role of U1 snRNP and Models for the Antagonistic Effects of SF2/ASF and hnRNP A1.

I. C. Eperon, O. V. Makarova, A. Mayeda, S. H. Munroe, J. F. Cáceres, D. G. Hayward, and A. R. Krainer (2000)
Mol. Cell. Biol. 20, 8303-8318
 |  Abstract »  |  Full Text »

Overexpression of Essential Splicing Factor ASF/SF2 Blocks the Temporal Shift in Adenovirus Pre-mRNA Splicing and Reduces Virus Progeny Formation.

M. Molin and G. Akusjärvi (2000)
J. Virol. 74, 9002-9009
 |  Abstract »  |  Full Text »

An Intronic Splicing Silencer Causes Skipping of the IIIb Exon of Fibroblast Growth Factor Receptor 2 through Involvement of Polypyrimidine Tract Binding Protein.

R. P. Carstens, E. J. Wagner, and M. A. Garcia-Blanco (2000)
Mol. Cell. Biol. 20, 7388-7400
 |  Abstract »  |  Full Text »

The Acute Myeloid Leukemia-Associated Protein, Dek, Forms a Splicing-Dependent Interaction with Exon-Product Complexes.

T. McGarvey, E. Rosonina, S. McCracken, Q. Li, R. Arnaout, E. Mientjes, J. A. Nickerson, D. Awrey, J. Greenblatt, G. Grosveld, et al. (2000)
J. Cell Biol. 150, 309-320
 |  Abstract »  |  Full Text »  |  PDF »

Cellular and viral splicing factors can modify the splicing pattern of CFTR transcripts carrying splicing mutations.

M. Nissim-Rafinia, O. Chiba-Falek, G. Sharon, A. Boss, and B. Kerem (2000)
Hum. Mol. Genet. 9, 1771-1778
 |  Abstract »  |  Full Text »  |  PDF »

Optimization of a Weak 3' Splice Site Counteracts the Function of a Bovine Papillomavirus Type 1 Exonic Splicing Suppressor In Vitro and In Vivo.

Z.-M. Zheng, J. Quintero, E. S. Reid, C. Gocke, and C. C. Baker (2000)
J. Virol. 74, 5902-5910
 |  Abstract »  |  Full Text »

TLS-ERG Leukemia Fusion Protein Inhibits RNA Splicing Mediated by Serine-Arginine Proteins.

L. Yang, L. J. Embree, and D. D. Hickstein (2000)
Mol. Cell. Biol. 20, 3345-3354
 |  Abstract »  |  Full Text »

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