Science 9 September 1994: Vol. 265. no. 5178, pp. 1596 - 1599 DOI: 10.1126/science.8079174

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Articles

p75 and TrkA Signaling Regulates Sympathetic Neuronal Firing Patterns via Differential Modulation of Voltage-Gated Currents.

J. A. Luther and S. J. Birren (2009)
J. Neurosci. 29, 5411-5424
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Cardiovascular Actions of Neurotrophins.

A. Caporali and C. Emanueli (2009)
Physiol Rev 89, 279-308
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Mitochondrial Superoxide Production and Nuclear Factor Erythroid 2-Related Factor 2 Activation in p75 Neurotrophin Receptor-Induced Motor Neuron Apoptosis.

M. Pehar, M. R. Vargas, K. M. Robinson, P. Cassina, P. J. Diaz-Amarilla, T. M. Hagen, R. Radi, L. Barbeito, and J. S. Beckman (2007)
J. Neurosci. 27, 7777-7785
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BEX2 Is Overexpressed in a Subset of Primary Breast Cancers and Mediates Nerve Growth Factor/Nuclear Factor-{kappa}B Inhibition of Apoptosis in Breast Cancer Cell Lines.

A. Naderi, A. E. Teschendorff, J. Beigel, M. Cariati, I. O. Ellis, J. D. Brenton, and C. Caldas (2007)
Cancer Res. 67, 6725-6736
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PSA-NCAM in postnatally generated immature neurons of the olfactory bulb: a crucial role in regulating p75 expression and cell survival.

E. Gascon, L. Vutskits, B. Jenny, P. Durbec, and J. Z. Kiss (2007)
Development 134, 1181-1190
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Unraveling the Story of NGF-mediated Sensitization of Nociceptive Sensory Neurons: ON or OFF the Trks?.

G. D. Nicol and M. R. Vasko (2007)
Mol. Interv. 7, 26-41
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Neurotrophin-regulated signalling pathways.

L. F Reichardt (2006)
Phil Trans R Soc B 361, 1545-1564
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Intracellular sphingosine 1-phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons.

Y. H. Zhang, M. R. Vasko, and G. D. Nicol (2006)
J. Physiol. 575, 101-113
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Role for calcium/calmodulin-dependent protein kinase II in the p75-mediated regulation of sympathetic cholinergic transmission.

J. D. Slonimsky, M. D. Mattaliano, J.-i. Moon, L. C. Griffith, and S. J. Birren (2006)
PNAS 103, 2915-2919
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Sensory Neurons From Nf1 Haploinsufficient Mice Exhibit Increased Excitability.

Y. Wang, G. D. Nicol, D. W. Clapp, and C. M. Hingtgen (2005)
J Neurophysiol 94, 3670-3676
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Microglia-derived Pronerve Growth Factor Promotes Photoreceptor Cell Death via p75 Neurotrophin Receptor.

B. Srinivasan, C. H. Roque, B. L. Hempstead, M. R. Al-Ubaidi, and R. S. Roque (2004)
J. Biol. Chem. 279, 41839-41845
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Brain metastases in melanoma: Roles of neurotrophins.

Y. Denkins, J. Reiland, M. Roy, N. D. Sinnappah-Kang, J. Galjour, B. P. Murry, J. Blust, R. Aucoin, and D. Marchetti (2004)
Neuro-oncol 6, 154-165
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Regulation of Interleukin Receptor-associated Kinase (IRAK) Phosphorylation and Signaling by Iota Protein Kinase C.

V. Mamidipudi, C. Lin, M. L. Seibenhener, and M. W. Wooten (2004)
J. Biol. Chem. 279, 4161-4165
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Nerve Growth Factor-induced Glutamate Release Is via p75 Receptor, Ceramide, and Ca2+ from Ryanodine Receptor in Developing Cerebellar Neurons.

T. Numakawa, H. Nakayama, S. Suzuki, T. Kubo, F. Nara, Y. Numakawa, D. Yokomaku, T. Araki, T. Ishimoto, A. Ogura, et al. (2003)
J. Biol. Chem. 278, 41259-41269
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p75 Neurotrophin Receptor Protects Primary Cultures of Human Neurons against Extracellular Amyloid {beta} Peptide Cytotoxicity.

Y. Zhang, Y. Hong, Y. Bounhar, M. Blacker, X. Roucou, O. Tounekti, E. Vereker, W. J. Bowers, H. J. Federoff, C. G. Goodyer, et al. (2003)
J. Neurosci. 23, 7385-7394
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Ceramide in Nitric Oxide Inhibition of Glioma Cell Growth. EVIDENCE FOR THE INVOLVEMENT OF CERAMIDE TRAFFIC.

P. Viani, P. Giussani, L. Brioschi, R. Bassi, V. Anelli, G. Tettamanti, and L. Riboni (2003)
J. Biol. Chem. 278, 9592-9601
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Programmed cell death in the developing inner ear is balanced by nerve growth factor and insulin-like growth factor I.

L. M. Frago, S. Canon, E. J. de la Rosa, Y. Leon, and I. Varela-Nieto (2003)
J. Cell Sci. 116, 475-486
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Role of ceramide in TNF-alpha -induced impairment of endothelium-dependent vasorelaxation in coronary arteries.

D. X. Zhang, F.-X. Yi, A.-P. Zou, and P.-L. Li (2002)
Am J Physiol Heart Circ Physiol 283, H1785-H1794
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Ceramide, a putative second messenger for nerve growth factor, modulates the TTX-resistant Na+ current and delayed rectifier K+ current in rat sensory neurons.

Y H Zhang, M R Vasko, and G D Nicol (2002)
J. Physiol. 544, 385-402
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Testis Developmental Phenotypes in Neurotropin Receptor trkA and trkC Null Mutations: Role in Formation of Seminiferous Cords and Germ Cell Survival.

A. S. Cupp, L. Tessarollo, and M. K. Skinner (2002)
Biol Reprod 66, 1838-1845
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Nerve Growth Factor-induced p75-mediated Death of Cultured Hippocampal Neurons Is Age-dependent and Transduced through Ceramide Generated by Neutral Sphingomyelinase.

A. B. Brann, M. Tcherpakov, I. M. Williams, A. H. Futerman, and M. Fainzilber (2002)
J. Biol. Chem. 277, 9812-9818
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Nerve Growth Factor Regulates Dopamine D2 Receptor Expression in Prolactinoma Cell Lines via p75NGFR-Mediated Activation of Nuclear Factor-{kappa}B.

C. Fiorentini, N. Guerra, M. Facchetti, A. Finardi, L. Tiberio, L. Schiaffonati, P. Spano, and C. Missale (2002)
Mol. Endocrinol. 16, 353-366
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Activation of Rac GTPase by p75 Is Necessary for c-jun N-Terminal Kinase-Mediated Apoptosis.

A. W. Harrington, J. Y. Kim, and S. O. Yoon (2002)
J. Neurosci. 22, 156-166
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A Novel p75NTR Signaling Pathway Promotes Survival, Not Death, of Immunopurified Neocortical Subplate Neurons.

M. F. DeFreitas, P. S. McQuillen, and C. J. Shatz (2001)
J. Neurosci. 21, 5121-5129
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Sphingomyelin metabolites inhibit sphingomyelin synthase and CTP:phosphocholine cytidylyltransferase.

J. Vivekananda, D. Smith, and R. J. King (2001)
Am J Physiol Lung Cell Mol Physiol 281, L98-L107
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Nerve Growth Factor Is Required for Early Follicular Development in the Mammalian Ovary.

G. A. Dissen, C. Romero, A. N. Hirshfield, and S. R. Ojeda (2001)
Endocrinology 142, 2078-2086
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Subtype-Specific Translocation of the {delta} Subtype of Protein Kinase C and Its Activation by Tyrosine Phosphorylation Induced by Ceramide in HeLa Cells.

T. Kajimoto, S. Ohmori, Y. Shirai, N. Sakai, and N. Saito (2001)
Mol. Cell. Biol. 21, 1769-1783
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Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system.

M. Bibel and Y.-A. Barde (2000)
Genes & Dev. 14, 2919-2937
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Neurotrophins Induce Death of Hippocampal Neurons via the p75 Receptor.

W. J. Friedman (2000)
J. Neurosci. 20, 6340-6346
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NG2-Positive Oligodendrocyte Progenitor Cells in Adult Human Brain and Multiple Sclerosis Lesions.

A. Chang, A. Nishiyama, J. Peterson, J. Prineas, and B. D. Trapp (2000)
J. Neurosci. 20, 6404-6412
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Intraovarian Excess of Nerve Growth Factor Increases Androgen Secretion and Disrupts Estrous Cyclicity in the Rat.

G. A. Dissen, H. E. Lara, V. Leyton, A. Paredes, D. F. Hill, M. E. Costa, A. Martinez-Serrano, and S. R. Ojeda (2000)
Endocrinology 141, 1073-1082
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Unscheduled re-entry into the cell cycle induced by NGF precedes cell death in nascent retinal neurones.

J. Frade (2000)
J. Cell Sci. 113, 1139-1148
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Role of Neurotropins in Rat Embryonic Testis Morphogenesis (Cord Formation).

E. Levine, A. S. Cupp, and M. K. Skinner (2000)
Biol Reprod 62, 132-142
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CD40 Signals Apoptosis through FAN-regulated Activation of the Sphingomyelin-Ceramide Pathway.

B. Segui, N. Andrieu-Abadie, S. Adam-Klages, O. Meilhac, D. Kreder, V. Garcia, A. P. Bruno, J.-P. Jaffrezou, R. Salvayre, M. Kronke, et al. (1999)
J. Biol. Chem. 274, 37251-37258
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Nerve Growth Factor Signaling in Caveolae-like Domains at the Plasma Membrane.

C.-s. Huang, J. Zhou, A. K. Feng, C. C. Lynch, J. Klumperman, S. J. DeArmond, and W. C. Mobley (1999)
J. Biol. Chem. 274, 36707-36714
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Adenosine A2A Receptor mRNA Regulation by Nerve Growth Factor Is TrkA-, Src-, and Ras-dependent via Extracellular Regulated Kinase and Stress-activated Protein Kinase/c-Jun NH2-terminal Kinase.

R. L. Malek, Z. Nie, V. Ramkumar, and N. H. Lee (1999)
J. Biol. Chem. 274, 35499-35504
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Cholinergic Septal Afferent Terminals Preferentially Contact Neuropeptide Y-Containing Interneurons Compared to Parvalbumin-Containing Interneurons in the Rat Dentate Gyrus.

K. D. Dougherty and T. A. Milner (1999)
J. Neurosci. 19, 10140-10152
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Caveolins, Liquid-Ordered Domains, and Signal Transduction.

E. J. Smart, G. A. Graf, M. A. McNiven, W. C. Sessa, J. A. Engelman, P. E. Scherer, T. Okamoto, and M. P. Lisanti (1999)
Mol. Cell. Biol. 19, 7289-7304
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Aberrant Sphingolipid Signaling Is Involved in the Resistance of Prostate Cancer Cell Lines to Chemotherapy.

X.-Z. Wang, J. R. Beebe, L. Pwiti, A. Bielawska, and M. J. Smyth (1999)
Cancer Res. 59, 5842-5848
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A Role of p75 in NGF-Mediated Down-Regulation of the A2A Adenosine Receptors in PC12 Cells.

Z. Nie, Y. Mei, R. L. Malek, A. Marcuzzi, N. H. Lee, and V. Ramkumar (1999)
Mol. Pharmacol. 56, 947-954
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Mass Spectrometric Identification of Increased C16 Ceramide Levels During Apoptosis.

R. L. Thomas Jr., C. M. Matsko, M. T. Lotze, and A. A. Amoscato (1999)
J. Biol. Chem. 274, 30580-30588
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Ceramide Signaling Downstream of the p75 Neurotrophin Receptor Mediates the Effects of Nerve Growth Factor on Outgrowth of Cultured Hippocampal Neurons.

A. B. Brann, R. Scott, Y. Neuberger, D. Abulafia, S. Boldin, M. Fainzilber, and A. H. Futerman (1999)
J. Neurosci. 19, 8199-8206
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Spatiotemporal Patterns of Expression of Neurotrophins and Neurotrophin Receptors in Mice Suggest Functional Roles in Testicular and Epididymal Morphogenesis.

M.A. Russo, M.L. Giustizieri, A. Favale, M.C. Fantini, L. Campagnolo, D. Konda, F. Germano, D. Farini, C. Manna, and G. Siracusa (1999)
Biol Reprod 61, 1123-1132
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Nerve Growth Factor (NGF)-induced Calcium Influx and Intracellular Calcium Mobilization in 3T3 Cells Expressing NGF Receptors.

H. Jiang, K. Takeda, P. Lazarovici, Y. Katagiri, Z.-X. Yu, G. Dickens, A. Chabuk, X.-W. Liu, V. Ferrans, and G. Guroff (1999)
J. Biol. Chem. 274, 26209-26216
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Regulation of Mitogen-Activated Protein Kinases by Sphingolipid Products in Oligodendrocytes.

H. Hida, S. Nagano, M. Takeda, and B. Soliven (1999)
J. Neurosci. 19, 7458-7467
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p75 Neurotrophin Receptor Expression Is Induced in Apoptotic Neurons After Seizure.

P. P. Roux, M. A. Colicos, P. A. Barker, and T. E. Kennedy (1999)
J. Neurosci. 19, 6887-6896
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Divergent Cellular Differentiation Pathways during the Invasive Stage of Cutaneous Malignant Melanoma Progression.

J. A. Reed, B. Finnerty, and A. P. Albino (1999)
Am. J. Pathol. 155, 549-555
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Role of Sphingosine 1-Phosphate in the Mitogenesis Induced by Oxidized Low Density Lipoprotein in Smooth Muscle Cells via Activation of Sphingomyelinase, Ceramidase, and Sphingosine Kinase.

N. Auge, M. Nikolova-Karakashian, S. Carpentier, S. Parthasarathy, A. Negre-Salvayre, R. Salvayre, A. H. Merrill Jr., and T. Levade (1999)
J. Biol. Chem. 274, 21533-21538
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The p75 Neurotrophin Receptor (p75NTR) Alters Tumor Necrosis Factor-mediated NF-kappa B Activity under Physiological Conditions, but Direct p75NTR-mediated NF-kappa B Activation Requires Cell Stress.

A. L. Bhakar, P. P. Roux, C. Lachance, D. Kryl, C. Zeindler, and P. A. Barker (1999)
J. Biol. Chem. 274, 21443-21449
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Functionally Antagonistic Interactions between the TrkA and p75 Neurotrophin Receptors Regulate Sympathetic Neuron Growth and Target Innervation.

J. Kohn, R. S. Aloyz, J. G. Toma, M. Haak-Frendscho, and F. D. Miller (1999)
J. Neurosci. 19, 5393-5408
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced Neurotrophin-Induced Axon Growth in Myelinated Portions of the CNS in Mice Lacking the p75 Neurotrophin Receptor.

G. S. Walsh, K. M. Krol, K. A. Crutcher, and M. D. Kawaja (1999)
J. Neurosci. 19, 4155-4168
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Pathway for Tumor Necrosis Factor-alpha and Ceramide Signaling Involving Sequential Activation of Tyrosine Kinase, p21ras, and Phosphatidylinositol 3-Kinase.

A. N. Hanna, E. Y. W. Chan, J. Xu, J. C. Stone, and D. N. Brindley (1999)
J. Biol. Chem. 274, 12722-12729
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The Signaling Adapter FRS-2 Competes with Shc for Binding to the Nerve Growth Factor Receptor TrkA. A MODEL FOR DISCRIMINATING PROLIFERATION AND DIFFERENTIATION.

S. O. Meakin, J. I. S. MacDonald, E. A. Gryz, C. J. Kubu, and J. M. Verdi (1999)
J. Biol. Chem. 274, 9861-9870
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Bradykinin inhibits ceramide production and activates phospholipase D in rabbit cortical collecting duct cells.

G. Liu, L. Kleine, R. Nasrallah, and R. L. Hebert (1999)
Am J Physiol Renal Physiol 276, F589-F598
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Caveolin Interacts with Trk A and p75NTR and Regulates Neurotrophin Signaling Pathways.

T. R. Bilderback, V.-R. Gazula, M. P. Lisanti, and R. T. Dobrowsky (1999)
J. Biol. Chem. 274, 257-263
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Absence of the p75 Neurotrophin Receptor Alters the Pattern of Sympathosensory Sprouting in the Trigeminal Ganglia of Mice Overexpressing Nerve Growth Factor.

G. S. Walsh, K. M. Krol, and M. D. Kawaja (1999)
J. Neurosci. 19, 258-273
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Purification and Characterization of a Membrane Bound Neutral pH Optimum Magnesium-dependent and Phosphatidylserine-stimulated Sphingomyelinase from Rat Brain.

B. Liu, D. F. Hassler, G. K. Smith, K. Weaver, and Y. A. Hannun (1998)
J. Biol. Chem. 273, 34472-34479
 |  Abstract »  |  Full Text »  |  PDF »

Ceramide Regulates the Transcription of Cyclooxygenase-2. EVIDENCE FOR INVOLVEMENT OF EXTRACELLULAR SIGNAL-REGULATED KINASE/c-Jun N-TERMINAL KINASE AND p38 MITOGEN-ACTIVATED PROTEIN KINASE PATHWAYS.

K. Subbaramaiah, W. J. Chung, and A. J. Dannenberg (1998)
J. Biol. Chem. 273, 32943-32949
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Involvement of Ras/MAP Kinase in the Regulation of Ca2+ Channels in Adult Bullfrog Sympathetic Neurons by Nerve Growth Factor.

S. Lei, W. F. Dryden, and P. A. Smith (1998)
J Neurophysiol 80, 1352-1361
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Ceramide, a mediator of interleukin 1, tumour necrosis factor alpha , as well as Fas receptor signalling, induces apoptosis of rheumatoid arthritis synovial cells.

N. Mizushima, H. Kohsaka, and N. Miyasaka (1998)
Ann Rheum Dis 57, 495-499
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Ceramide Activates NFkappa B by Inducing the Processing of p105.

M. P. Boland and L. A. J. O'Neill (1998)
J. Biol. Chem. 273, 15494-15500
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Nerve growth factor abrogates the tumorigenicity of human small cell lung cancer cell lines.

C. Missale, A. Codignola, S. Sigala, A. Finardi, M. Paez-Pereda, E. Sher, and P. Spano (1998)
PNAS 95, 5366-5371
 |  Abstract »  |  Full Text »  |  PDF »

Cloned mammalian neutral sphingomyelinase: Functions in sphingolipid signaling?.

S. Tomiuk, K. Hofmann, M. Nix, M. Zumbansen, and W. Stoffel (1998)
PNAS 95, 3638-3643
 |  Abstract »  |  Full Text »  |  PDF »

Ceramide Formation Leads to Caspase-3 Activation during Hypoxic PC12 Cell Death. INHIBITORY EFFECTS OF Bcl-2 ON CERAMIDE FORMATION AND CASPASE-3 ACTIVATION.

S.-i. Yoshimura, Y. Banno, S. Nakashima, K. Takenaka, H. Sakai, Y. Nishimura, N. Sakai, S. Shimizu, Y. Eguchi, Y. Tsujimoto, et al. (1998)
J. Biol. Chem. 273, 6921-6927
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Necrosis Factor-alpha Stimulates the Maturation of Sterol Regulatory Element Binding Protein-1 in Human Hepatocytes through the Action of Neutral Sphingomyelinase.

J. F. Lawler Jr., M. Yin, A. M. Diehl, E. Roberts, and S. Chatterjee (1998)
J. Biol. Chem. 273, 5053-5059
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The p75 Neurotrophin Receptor Mediates Neuronal Apoptosis and Is Essential for Naturally Occurring Sympathetic Neuron Death.

S. X. Bamji, M. Majdan, C. D. Pozniak, D. J. Belliveau, R. Aloyz, J. Kohn, C. G. Causing, and F. D. Miller (1998)
J. Cell Biol. 140, 911-923
 |  Abstract »  |  Full Text »  |  PDF »

p75 Neurotrophin Receptor Expression on Adult Human Oligodendrocytes: Signaling without Cell Death in Response to NGF.

U. Ladiwala, C. Lachance, S. J. J. Simoneau, A. Bhakar, P. A. Barker, and J. P. Antel (1998)
J. Neurosci. 18, 1297-1304
 |  Abstract »  |  Full Text »  |  PDF »

Nerve growth factor and ceramides modulate cell death in the early developing inner ear.

L. Frago, Y Leon, E. de la Rosa, A Gomez-Munoz, and I Varela-Nieto (1998)
J. Cell Sci. 111, 549-556
 |  Abstract »  |  PDF »

Retrograde Signaling in the Development and Modification of Synapses.

R. M. FITZSIMONDS and M.-M. POO (1998)
Physiol Rev 78, 143-170
 |  Abstract »  |  Full Text »  |  PDF »

A Second Determinant of Binding to the p75 Neurotrophin Receptor Revealed by Alanine-scanning Mutagenesis of a Conserved Loop in Nerve Growth Factor.

M. Ryden and C. F. Ibanez (1997)
J. Biol. Chem. 272, 33085-33091
 |  Abstract »  |  Full Text »  |  PDF »

Nerve Growth Factor Modulates Synaptic Transmission between Sympathetic Neurons and Cardiac Myocytes.

S. T. Lockhart, G. G. Turrigiano, and S. J. Birren (1997)
J. Neurosci. 17, 9573-9582
 |  Abstract »  |  Full Text »  |  PDF »

Absence of p75NTR Causes Increased Basal Forebrain Cholinergic Neuron Size, Choline Acetyltransferase Activity, and Target Innervation.

T. T. Yeo, J. Chua-Couzens, L. L. Butcher, D. E. Bredesen, J. D. Cooper, J. S. Valletta, W. C. Mobley, and F. M. Longo (1997)
J. Neurosci. 17, 7594-7605
 |  Abstract »  |  Full Text »  |  PDF »

Brain-derived Neurotrophic Factor Binding to the p75 Neurotrophin Receptor Reduces TrkA Signaling While Increasing Serine Phosphorylation in the TrkA Intracellular Domain.

I. J. MacPhee and P. A. Barker (1997)
J. Biol. Chem. 272, 23547-23551
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of Sphingosine 1-Phosphate in Nerve Growth Factor-Mediated Neuronal Survival and Differentiation.

L. C. Edsall, G. G. Pirianov, and S. Spiegel (1997)
J. Neurosci. 17, 6952-6960
 |  Abstract »  |  Full Text »  |  PDF »

Transgenic Mice Expressing the Intracellular Domain of the p75 Neurotrophin Receptor Undergo Neuronal Apoptosis.

M. Majdan, C. Lachance, A. Gloster, R. Aloyz, C. Zeindler, S. Bamji, A. Bhakar, D. Belliveau, J. Fawcett, F. D. Miller, et al. (1997)
J. Neurosci. 17, 6988-6998
 |  Abstract »  |  Full Text »  |  PDF »

A signaling organelle containing the nerve growth factor-activated receptor tyrosine kinase, TrkA.

M. L. Grimes, E. Beattie, and W. C. Mobley (1997)
PNAS 94, 9909-9914
 |  Abstract »  |  Full Text »  |  PDF »

Implication of Mitochondrial Hydrogen Peroxide Generation in Ceramide-induced Apoptosis.

A. Quillet-Mary, J.-P. Jaffrezou, V. Mansat, C. Bordier, J. Naval, and G. Laurent (1997)
J. Biol. Chem. 272, 21388-21395
 |  Abstract »  |  Full Text »  |  PDF »

The trkA Receptor Mediates Growth Cone Turning toward a Localized Source of Nerve Growth Factor.

G. Gallo, F. B. Lefcort, and P. C. Letourneau (1997)
J. Neurosci. 17, 5445-5454
 |  Abstract »  |  Full Text »  |  PDF »

Phospholipase A2 Is Necessary for Tumor Necrosis Factor alpha -induced Ceramide Generation in L929 Cells.

S. Jayadev, H. L. Hayter, N. Andrieu, C. J. Gamard, B. Liu, R. Balu, M. Hayakawa, F. Ito, and Y. A. Hannun (1997)
J. Biol. Chem. 272, 17196-17203
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of the Neutral Magnesium-dependent Sphingomyelinase by Glutathione.

B. Liu and Y. A. Hannun (1997)
J. Biol. Chem. 272, 16281-16287
 |  Abstract »  |  Full Text »  |  PDF »

Differential Modulation of Neuron Survival during Development by Nerve Growth Factor Binding to the p75 Neurotrophin Receptor.

M. Ryden, B. Hempstead, and C. F. Ibanez (1997)
J. Biol. Chem. 272, 16322-16328
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Neurotrophins Protect Cultured Cerebellar Granule Neurons against the Early Phase of Cell Death by a TwoComponent Mechanism.

M. J. Courtney, K. E. O. Akerman, and E. T. Coffey (1997)
J. Neurosci. 17, 4201-4211
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The Low-Affinity Neurotrophin Receptor p75 Regulates the Function But Not the Selective Survival of Specific Subpopulations of Sensory Neurons.

C. L. Stucky and M. Koltzenburg (1997)
J. Neurosci. 17, 4398-4405
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Distinct Roles for Ceramide and Glucosylceramide at Different Stages of Neuronal Growth.

A. Schwarz and A. H. Futerman (1997)
J. Neurosci. 17, 2929-2938
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Association of p75NTR with Caveolin and Localization of Neurotrophin-induced Sphingomyelin Hydrolysis to Caveolae.

T. R. Bilderback, R. J. Grigsby, and R. T. Dobrowsky (1997)
J. Biol. Chem. 272, 10922-10927
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Expression of Neutral Sphingomyelinase Identifies a Distinct Pool of Sphingomyelin Involved in Apoptosis.

P. Zhang, B. Liu, G. M. Jenkins, Y. A. Hannun, and L. M. Obeid (1997)
J. Biol. Chem. 272, 9609-9612
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Pituitary Cytokine and Growth Factor Expression and Action.

D. Ray and S. Melmed (1997)
Endocr. Rev. 18, 206-228
 |  Abstract »  |  Full Text »

Bacterial Attachment To Uro-Epithelial Cells: Mechanisms and Consequences.

H. Connell, M. Hedlund, W. Agace, and C. Svanborg (1997)
Advances in Dental Research 11, 50-58
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Tyrosine Kinase Receptors Concentrated in Caveolae-like Domains from Neuronal Plasma Membrane.

C. Wu, S. Butz, Y.-s. Ying, and R. G.W. Anderson (1997)
J. Biol. Chem. 272, 3554-3559
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Elevation of Ceramide within Distal Neurites Inhibits Neurite Growth in Cultured Rat Sympathetic Neurons.

E. I.P. de Chaves, M. Bussiere, D. E. Vance, R. B. Campenot, and J. E. Vance (1997)
J. Biol. Chem. 272, 3028-3035
 |  Abstract »  |  Full Text »  |  PDF »

NGF and Neurotrophin-3 Both Activate TrkA on Sympathetic Neurons but Differentially Regulate Survival and Neuritogenesis.

D. J. Belliveau, I. Krivko, J. Kohn, C. Lachance, C. Pozniak, D. Rusakov, D. Kaplan, and F. D. Miller (1997)
J. Cell Biol. 136, 375-388
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Ceramide-induced Translocation of Protein Kinase C-delta and -epsilon to the Cytosol. IMPLICATIONS IN APOPTOSIS.

H. Sawai, T. Okazaki, Y. Takeda, M. Tashima, H. Sawada, M. Okuma, S. Kishi, H. Umehara, and N. Domae (1997)
J. Biol. Chem. 272, 2452-2458
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Ceramide Inhibits Antigen Uptake and Presentation by Dendritic Cells.

F. Sallusto, C. Nicolo, R. De Maria, S. Corinti, and R. Testi (1996)
J. Exp. Med. 184, 2411-2416
 |  Abstract »  |  Full Text »  |  PDF »

Nerve Growth Factor and Neurotrophin-3 Differentially Regulate the Proliferation and Survival of Developing Rat Brain Oligodendrocytes.

R. I. Cohen, R. Marmur, W. T. Norton, M. F. Mehler, and J. A. Kessler (1996)
J. Neurosci. 16, 6433-6442
 |  Abstract »  |  Full Text »  |  PDF »

Mice Lacking Brain-Derived Neurotrophic Factor Exhibit Visceral Sensory Neuron Losses Distinct from Mice Lacking NT4 and Display a Severe Developmental Deficit in Control of Breathing.

J. T. Erickson, J. C. Conover, V. Borday, J. Champagnat, M. Barbacid, G. Yancopoulos, and D. M. Katz (1996)
J. Neurosci. 16, 5361-5371
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Neurotrophins Stimulate the Release of Dopamine from Rat Mesencephalic Neurons via Trk and p75Lntr Receptors.

A. Blochl and C. Sirrenberg (1996)
J. Biol. Chem. 271, 21100-21107
 |  Abstract »  |  Full Text »  |  PDF »

The Sphingomyelin-Ceramide Signaling Pathway Is Involved in Oxidized Low Density Lipoprotein-induced Cell Proliferation.

N. Auge, N. Andrieu, A. Negre-Salvayre, J.-C. Thiers, T. Levade, and R. Salvayre (1996)
J. Biol. Chem. 271, 19251-19255
 |  Abstract »  |  Full Text »  |  PDF »

(1S,2R)-D-erythro-2-(N-Myristoylamino)-1-phenyl-1-propanol as an Inhibitor of Ceramidase.

A. Bielawska, M. S. Greenberg, D. Perry, S. Jayadev, J. A. Shayman, C. McKay, and Y. A. Hannun (1996)
J. Biol. Chem. 271, 12646-12654
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REVIEW {blacksquare} : Keeping Neurons Alive: The Molecular Control of Apoptosis (Part I.

D. E. Bredesen (1996)
Neuroscientist 2, 181-190
 |  Abstract »  |  PDF »

Retrograde Transport of Neurotrophins from the Eye to the Brain in Chick Embryos: Roles of the p75NTR and trkB Receptors.

C. S. von Bartheld, R. Williams, F. Lefcort, D. O. Clary, L. F. Reichardt, and M. Bothwell (1996)
J. Neurosci. 16, 2995-3008
 |  Abstract »  |  Full Text »  |  PDF »

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