Science 2 September 1994: Vol. 265. no. 5177, pp. 1464 - 1467 DOI: 10.1126/science.8073293

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Articles

A Role for Synaptic Zinc in Activity-Dependent A{beta} Oligomer Formation and Accumulation at Excitatory Synapses.

A. Deshpande, H. Kawai, R. Metherate, C. G. Glabe, and J. Busciglio (2009)
J. Neurosci. 29, 4004-4015
 |  Abstract »  |  Full Text »  |  PDF »

Structure of the Zinc Transporter YiiP.

M. Lu and D. Fu (2007)
Science 317, 1746-1748
 |  Abstract »  |  Full Text »  |  PDF »

Engineering metal ion coordination to regulate amyloid fibril assembly and toxicity.

J. Dong, J. M. Canfield, A. K. Mehta, J. E. Shokes, B. Tian, W. S. Childers, J. A. Simmons, Z. Mao, R. A. Scott, K. Warncke, et al. (2007)
PNAS 104, 13313-13318
 |  Abstract »  |  Full Text »  |  PDF »

Rodent Abeta Modulates the Solubility and Distribution of Amyloid Deposits in Transgenic Mice.

J. L. Jankowsky, L. H. Younkin, V. Gonzales, D. J. Fadale, H. H. Slunt, H. A. Lester, S. G. Younkin, and D. R. Borchelt (2007)
J. Biol. Chem. 282, 22707-22720
 |  Abstract »  |  Full Text »  |  PDF »

Subunit-specific modulation of T-type calcium channels by zinc.

A. Traboulsie, J. Chemin, M. Chevalier, J.-F. Quignard, J. Nargeot, and P. Lory (2007)
J. Physiol. 578, 159-171
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced Amyloidogenic Metabolism of the Amyloid beta-Protein Precursor in the X11L-deficient Mouse Brain.

Y. Sano, A. Syuzo-Takabatake, T. Nakaya, Y. Saito, S. Tomita, S. Itohara, and T. Suzuki (2006)
J. Biol. Chem. 281, 37853-37860
 |  Abstract »  |  Full Text »  |  PDF »

Alzheimer's centennial legacy: prospects for rational therapeutic intervention targeting the A{beta} amyloid pathway.

C. L. Masters and K. Beyreuther (2006)
Brain 129, 2823-2839
 |  Abstract »  |  Full Text »  |  PDF »

Acceleration of Amyloid beta-Peptide Aggregation by Physiological Concentrations of Calcium.

A. M. Isaacs, D. B. Senn, M. Yuan, J. P. Shine, and B. A. Yankner (2006)
J. Biol. Chem. 281, 27916-27923
 |  Abstract »  |  Full Text »  |  PDF »

Elevated cortical zinc in Alzheimer disease..

D. Religa, D. Strozyk, R. A. Cherny, I. Volitakis, V. Haroutunian, B. Winblad, J. Naslund, and A. I. Bush (2006)
Neurology 67, 69-75
 |  Abstract »  |  Full Text »  |  PDF »

Nicotine attenuates {beta}-amyloid-induced neurotoxicity by regulating metal homeostasis.

J. Zhang, Q. Liu, Q. Chen, N.-Q. Liu, F.-L. Li, Z.-B. Lu, C. Qin, H. Zhu, Y.-Y. Huang, W. He, et al. (2006)
FASEB J 20, 1212-1214
 |  Abstract »  |  Full Text »  |  PDF »

The Effect of A{beta} Conformation on the Metal Affinity and Aggregation Mechanism Studied by Circular Dichroism Spectroscopy..

Y.R. Chen, H.B. Huang, C.L. Chyan, M.S. Shiao, T.H. Lin, and Y.C. Chen (2006)
J. Biochem. 139, 733-740
 |  Abstract »  |  Full Text »  |  PDF »

Structural Changes of Region 1-16 of the Alzheimer Disease Amyloid beta-Peptide upon Zinc Binding and in Vitro Aging.

S. Zirah, S. A. Kozin, A. K. Mazur, A. Blond, M. Cheminant, I. Segalas-Milazzo, P. Debey, and S. Rebuffat (2006)
J. Biol. Chem. 281, 2151-2161
 |  Abstract »  |  Full Text »  |  PDF »

Perinatal {omega}-3 polyunsaturated fatty acid supply modifies brain zinc homeostasis during adulthood.

A. P. Jayasooriya, M. L. Ackland, M. L. Mathai, A. J. Sinclair, H. S. Weisinger, R. S. Weisinger, J. E. Halver, K. Kitajka, and L. G. Puskas (2005)
PNAS 102, 7133-7138
 |  Abstract »  |  Full Text »  |  PDF »

Catechol Oxidase-like Oxidation Chemistry of the 1-20 and 1-16 Fragments of Alzheimer's Disease-related {beta}-Amyloid Peptide: THEIR STRUCTURE-ACTIVITY CORRELATION AND THE FATE OF HYDROGEN PEROXIDE.

G. F. Z. da Silva, W. M. Tay, and L.-J. Ming (2005)
J. Biol. Chem. 280, 16601-16609
 |  Abstract »  |  Full Text »  |  PDF »

Autoantibodies to Redox-modified Oligomeric A{beta} Are Attenuated in the Plasma of Alzheimer's Disease Patients.

R. D. Moir, K. A. Tseitlin, S. Soscia, B. T. Hyman, M. C. Irizarry, and R. E Tanzi (2005)
J. Biol. Chem. 280, 17458-17463
 |  Abstract »  |  Full Text »  |  PDF »

Metal Ion-dependent Effects of Clioquinol on the Fibril Growth of an Amyloid {beta} Peptide.

B. Raman, T. Ban, K.-i. Yamaguchi, M. Sakai, T. Kawai, H. Naiki, and Y. Goto (2005)
J. Biol. Chem. 280, 16157-16162
 |  Abstract »  |  Full Text »  |  PDF »

Impact of antioxidants, zinc, and copper on cognition in the elderly: A randomized, controlled trial.

Age-Related Eye Disease Study Research Group (2004)
Neurology 63, 1705-1707
 |  Abstract »  |  Full Text »  |  PDF »

Increased tau Phosphorylation in Apolipoprotein E4 Transgenic Mice Is Associated with Activation of Extracellular Signal-regulated Kinase: MODULATION BY ZINC.

F. M. Harris, W. J. Brecht, Q. Xu, R. W. Mahley, and Y. Huang (2004)
J. Biol. Chem. 279, 44795-44801
 |  Abstract »  |  Full Text »  |  PDF »

Ionic Strength and Transition Metals Control PrPSc Protease Resistance and Conversion-inducing Activity.

K. Nishina, S. Jenks, and S. Supattapone (2004)
J. Biol. Chem. 279, 40788-40794
 |  Abstract »  |  Full Text »  |  PDF »

Copper Binding to the Amyloid-{beta} (A{beta}) Peptide Associated with Alzheimer's Disease: FOLDING, COORDINATION GEOMETRY, pH DEPENDENCE, STOICHIOMETRY, AND AFFINITY OF A{beta}-(1-28): INSIGHTS FROM A RANGE OF COMPLEMENTARY SPECTROSCOPIC TECHNIQUES.

C. D. Syme, R. C. Nadal, S. E. J. Rigby, and J. H. Viles (2004)
J. Biol. Chem. 279, 18169-18177
 |  Abstract »  |  Full Text »  |  PDF »

Neuronal Zinc Exchange with the Blood Vessel Wall Promotes Cerebral Amyloid Angiopathy in an Animal Model of Alzheimer's Disease.

A. L. Friedlich, J.-Y. Lee, T. van Groen, R. A. Cherny, I. Volitakis, T. B. Cole, R. D. Palmiter, J.-Y. Koh, and A. I. Bush (2004)
J. Neurosci. 24, 3453-3459
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen Decreases Zinc Transporter 3 Expression and Synaptic Vesicle Zinc Levels in Mouse Brain.

J.-Y. Lee, J.-H. Kim, S. H. Hong, J. Y. Lee, R. A. Cherny, A. I. Bush, R. D. Palmiter, and J.-Y. Koh (2004)
J. Biol. Chem. 279, 8602-8607
 |  Abstract »  |  Full Text »  |  PDF »

Metal Chelation Therapy for Alzheimer Disease.

R. N. Rosenberg (2003)
Arch Neurol 60, 1678-1679
 |  Full Text »  |  PDF »

Detangling Alzheimer's Disease.

L. Helmuth (2003)
Sci. Aging Knowl. Environ. 2003, oa2-2
 |  Abstract »  |  Full Text »  |  PDF »

Cu2+-induced modification of the kinetics of A{beta}(1-42) channels.

R. Bahadi, P. V. Farrelly, B. L. Kenna, C. C. Curtain, C. L. Masters, R. Cappai, K. J. Barnham, and J. I. Kourie (2003)
Am J Physiol Cell Physiol 285, C873-C880
 |  Abstract »  |  Full Text »  |  PDF »

Copper, {beta}-amyloid, and Alzheimer's disease: Tapping a sensitive connection.

A. I. Bush, C. L. Masters, and R. E. Tanzi (2003)
PNAS 100, 11193-11194
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Mindful of Metal.

M. Leslie (2003)
Sci. Aging Knowl. Environ. 2003, nf6-6
 |  Abstract »  |  Full Text »

Metal Ions, pH, and Cholesterol Regulate the Interactions of Alzheimer's Disease Amyloid-beta Peptide with Membrane Lipid.

C. C. Curtain, F. E. Ali, D. G. Smith, A. I. Bush, C. L. Masters, and K. J. Barnham (2003)
J. Biol. Chem. 278, 2977-2982
 |  Abstract »  |  Full Text »  |  PDF »

Zn(II)-free Dimethylargininase-1 (DDAH-1) Is Inhibited upon Specific Cys-S-Nitrosylation.

M. Knipp, O. Braun, P. M. Gehrig, R. Sack, and M. Vasak (2003)
J. Biol. Chem. 278, 3410-3416
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of Alzheimer's Disease Amyloid-beta Opposes the Age-dependent Elevations of Brain Copper and Iron.

C. J. Maynard, R. Cappai, I. Volitakis, R. A. Cherny, A. R. White, K. Beyreuther, C. L. Masters, A. I. Bush, and Q.-X. Li (2002)
J. Biol. Chem. 277, 44670-44676
 |  Abstract »  |  Full Text »  |  PDF »

An Iron-responsive Element Type II in the 5'-Untranslated Region of the Alzheimer's Amyloid Precursor Protein Transcript.

J. T. Rogers, J. D. Randall, C. M. Cahill, P. S. Eder, X. Huang, H. Gunshin, L. Leiter, J. McPhee, S. S. Sarang, T. Utsuki, et al. (2002)
J. Biol. Chem. 277, 45518-45528
 |  Abstract »  |  Full Text »  |  PDF »

Metalloenzyme-like Activity of Alzheimer's Disease beta -Amyloid. Cu-DEPENDENT CATALYTIC CONVERSION OF DOPAMINE, CHOLESTEROL, AND BIOLOGICAL REDUCING AGENTS TO NEUROTOXIC H2O2.

C. Opazo, X. Huang, R. A. Cherny, R. D. Moir, A. E. Roher, A. R. White, R. Cappai, C. L. Masters, R. E. Tanzi, N. C. Inestrosa, et al. (2002)
J. Biol. Chem. 277, 40302-40308
 |  Abstract »  |  Full Text »  |  PDF »

Amyloid Precursor Protein, Presenilins, and alpha -Synuclein: Molecular Pathogenesis and Pharmacological Applications in Alzheimer's Disease.

Y.-H. Suh and F. Checler (2002)
Pharmacol. Rev. 54, 469-525
 |  Abstract »  |  Full Text »  |  PDF »

Zinc Status Influences Zinc Transport by Porcine Brain Capillary Endothelial Cells.

H. M. Lehmann, B. B. Brothwell, L. P. Volak, and D. J. Bobilya (2002)
J. Nutr. 132, 2763-2768
 |  Abstract »  |  Full Text »  |  PDF »

Age-Related Eye Disease Study Caveats.

J. Ambati, B. K. Ambati, F. L. Ferris III, A. S. Lindblad, and R. C. Milton (2002)
Arch Ophthalmol 120, 997-999
 |  Full Text »  |  PDF »

A Novel Function of Monomeric Amyloid beta -Protein Serving as an Antioxidant Molecule against Metal-Induced Oxidative Damage.

K. Zou, J.-S. Gong, K. Yanagisawa, and M. Michikawa (2002)
J. Neurosci. 22, 4833-4841
 |  Abstract »  |  Full Text »  |  PDF »

The galvanization of beta -amyloid in Alzheimer's disease.

A. I. Bush and R. E. Tanzi (2002)
PNAS 99, 7317-7319
 |  Full Text »  |  PDF »

From the Cover: Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice.

J.-Y. Lee, T. B. Cole, R. D. Palmiter, S. W. Suh, and J.-Y. Koh (2002)
PNAS 99, 7705-7710
 |  Abstract »  |  Full Text »  |  PDF »

Magnesium Inhibits Spontaneous and Iron-induced Aggregation of alpha -Synuclein.

N. Golts, H. Snyder, M. Frasier, C. Theisler, P. Choi, and B. Wolozin (2002)
J. Biol. Chem. 277, 16116-16123
 |  Abstract »  |  Full Text »  |  PDF »

Amyloid {beta} protein forms ion channels: implications for Alzheimer's disease pathophysiology.

H. LIN, R. BHATIA, and R. LAL (2001)
FASEB J 15, 2433-2444
 |  Abstract »  |  Full Text »  |  PDF »

Detangling Alzheimer's Disease.

L. Helmuth (2001)
Sci. Aging Knowl. Environ. 2001, oa2-2
 |  Abstract »  |  Full Text »  |  PDF »

S100{beta} Interaction with Tau Is Promoted by Zinc and Inhibited by Hyperphosphorylation in Alzheimer's Disease.

W. H. Yu and P. E. Fraser (2001)
J. Neurosci. 21, 2240-2246
 |  Abstract »  |  Full Text »  |  PDF »

Changes in dietary zinc and copper affect zinc-status indicators of postmenopausal women, notably, extracellular superoxide dismutase and amyloid precursor proteins.

C. D Davis, D. B Milne, and F. H Nielsen (2000)
Am. J. Clinical Nutrition 71, 781-788
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative stress and Alzheimer disease1.

Y. Christen (2000)
Am. J. Clinical Nutrition 71, 621s-629s
 |  Abstract »  |  Full Text »  |  PDF »

Zinc Deficiency Exacerbates Loss in Blood-Brain Barrier Integrity Induced by Hyperoxia Measured by Dynamic MRI.

M. D. Noseworthy and T. M. Bray (2000)
Experimental Biology and Medicine 223, 175-182
 |  Abstract »  |  Full Text »

History of Zinc as Related to Brain Function.

H. H. Sandstead, C. J. Frederickson, and J. G. Penland (2000)
J. Nutr. 130, 496
 |  Abstract »  |  Full Text »

Controlling Polymerization of beta -Amyloid and Prion-derived Peptides with Synthetic Small Molecule Ligands.

P. Kuner, B. Bohrmann, L. O. Tjernberg, J. Naslund, G. Huber, S. Celenk, F. Gruninger-Leitch, J. G. Richards, R. Jakob-Roetne, J. A. Kemp, et al. (2000)
J. Biol. Chem. 275, 1673-1678
 |  Abstract »  |  Full Text »  |  PDF »

Aqueous Dissolution of Alzheimer's Disease Abeta Amyloid Deposits by Biometal Depletion.

R. A. Cherny, J. T. Legg, C. A. McLean, D. P. Fairlie, X. Huang, C. S. Atwood, K. Beyreuther, R. E. Tanzi, C. L. Masters, and A. I. Bush (1999)
J. Biol. Chem. 274, 23223-23228
 |  Abstract »  |  Full Text »  |  PDF »

Amyloid beta  Protein-(1-42) Forms Calcium-permeable, Zn2+-sensitive Channel.

S. K. Rhee, A. P. Quist, and R. Lal (1998)
J. Biol. Chem. 273, 13379-13382
 |  Abstract »  |  Full Text »  |  PDF »

Dramatic Aggregation of Alzheimer Abeta by Cu(II) Is Induced by Conditions Representing Physiological Acidosis.

C. S. Atwood, R. D. Moir, X. Huang, R. C. Scarpa, N. M. E. Bacarra, D. M. Romano, M. A. Hartshorn, R. E. Tanzi, and A. I. Bush (1998)
J. Biol. Chem. 273, 12817-12826
 |  Abstract »  |  Full Text »  |  PDF »

The alpha 5beta 1 Integrin Mediates Elimination of Amyloid-beta Peptide and Protects Against Apoptosis.

M. L. Matter, Z. Zhang, C. Nordstedt, and E. Ruoslahti (1998)
J. Cell Biol. 141, 1019-1030
 |  Abstract »  |  Full Text »  |  PDF »

Fibrillar beta -Amyloid Induces Microglial Phagocytosis, Expression of Inducible Nitric Oxide Synthase, and Loss of a Select Population of Neurons in the Rat CNS In Vivo.

D. T. Weldon, S. D. Rogers, J. R. Ghilardi, M. P. Finke, J. P. Cleary, E. O'Hare, W. P. Esler, J. E. Maggio, and P. W. Mantyh (1998)
J. Neurosci. 18, 2161-2173
 |  Abstract »  |  Full Text »  |  PDF »

Alzheimer-like Changes in Microtubule-associated Protein Tau Induced by Sulfated Glycosaminoglycans. INHIBITION OF MICROTUBULE BINDING, STIMULATION OF PHOSPHORYLATION, AND FILAMENT ASSEMBLY DEPEND ON THE DEGREE OF SULFATION.

M. Hasegawa, R. A. Crowther, R. Jakes, and M. Goedert (1997)
J. Biol. Chem. 272, 33118-33124
 |  Abstract »  |  Full Text »  |  PDF »

Amyloid beta -Protein (Abeta ) 1-40 But Not Abeta 1-42 Contributes to the Experimental Formation of Alzheimer Disease Amyloid Fibrils in Rat Brain.

R.-W. Shin, K. Ogino, A. Kondo, T. C. Saido, J. Q. Trojanowski, T. Kitamoto, and J. Tateishi (1997)
J. Neurosci. 17, 8187-8193
 |  Abstract »  |  Full Text »  |  PDF »

Zinc-induced Alzheimer's Abeta 1-40 Aggregation Is Mediated by Conformational Factors.

X. Huang, C. S. Atwood, R. D. Moir, M. A. Hartshorn, J.-P. Vonsattel, R. E. Tanzi, and A. I. Bush (1997)
J. Biol. Chem. 272, 26464-26470
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structures of the copper and nickel complexes of RNase A: Metal-induced interprotein interactions and identification of a novel copper binding motif.

R. Balakrishnan, N. Ramasubbu, K. I. Varughese, and R. Parthasarathy (1997)
PNAS 94, 9620-9625
 |  Abstract »  |  Full Text »  |  PDF »

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals.

M. A. Smith, P. L. R. Harris, L. M. Sayre, and G. Perry (1997)
PNAS 94, 9866-9868
 |  Abstract »  |  Full Text »  |  PDF »

Soluble Amyloid Abeta -(1-40) Exists as a Stable Dimer at Low Concentrations.

W. Garzon-Rodriguez, M. Sepulveda-Becerra, S. Milton, and C. G. Glabe (1997)
J. Biol. Chem. 272, 21037-21044
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of the Metallothionein-III Gene in Mice: Analysis of Brain Zinc, Behavior, and Neuron Vulnerability to Metals, Aging, and Seizures.

J. C. Erickson, G. Hollopeter, S. A. Thomas, G. J. Froelick, and R. D. Palmiter (1997)
J. Neurosci. 17, 1271-1281
 |  Abstract »  |  Full Text »  |  PDF »

The "Nonamyloidogenic" p3 Fragment (Amyloid beta 17-42) Is a Major Constituent of Down's Syndrome Cerebellar Preamyloid.

M. Lalowski, A. Golabek, C. A. Lemere, D. J. Selkoe, H. M. Wisniewski, R. C. Beavis, B. Frangione, and T. Wisniewski (1996)
J. Biol. Chem. 271, 33623-33631
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced Amyloidogenic Processing of the beta -Amyloid Precursor Protein in Gene-targeted Mice Bearing the Swedish Familial Alzheimer's Disease Mutations and a ``Humanized'' Abeta Sequence.

A. G. Reaume, D. S. Howland, S. P. Trusko, M. J. Savage, D. M. Lang, B. D. Greenberg, R. Siman, and R. W. Scott (1996)
J. Biol. Chem. 271, 23380-23388
 |  Abstract »  |  Full Text »  |  PDF »

The Serpin-Enzyme Complex Receptor Recognizes Soluble, Nontoxic Amyloid-beta Peptide but Not Aggregated, Cytotoxic Amyloid-beta Peptide.

K. Boland, M. Behrens, D. Choi, K. Manias, and DavidH. Perlmutter (1996)
J. Biol. Chem. 271, 18032-18044
 |  Abstract »  |  Full Text »  |  PDF »

The Interaction between Apolipoprotein E and Alzheimer's Amyloid beta-Peptide Is Dependent on beta-Peptide Conformation.

A. A. Golabek, C. Soto, T. Vogel, and T. Wisniewski (1996)
J. Biol. Chem. 271, 10602-10606
 |  Abstract »  |  Full Text »  |  PDF »

Water-soluble Abeta(N-40, N-42) Oligomers in Normal and Alzheimer Disease Brains.

Y.-M. Kuo, M. R. Emmerling, C. Vigo-Pelfrey, T. C. Kasunic, J. B. Kirkpatrick, G. H. Murdoch, M. J. Ball, and A. E. Roher (1996)
J. Biol. Chem. 271, 4077-4081
 |  Abstract »  |  Full Text »  |  PDF »

Neuronal Sorting and Processing of Amyloid Precursor Protein: Implications for Alzheimer's Disease.

P.J. Tienari, B. De Strooper, E. Ikonen, N. Ida, M. Simons, C.L. Masters, C.G. Dotti, and K. Beyreuther (1996)
Cold Spring Harb Symp Quant Biol 61, 575-585
 |  Abstract »  |  PDF »

Response.

A. I. Bush, R. D. Moir, K. M. Rosenkranz, and R. E. Tanzi (1995)
Science 268, 1921-1923
 |  PDF »

Neurology.

R. J. Joynt (1995)
JAMA 273, 1695-1697
 |  Abstract »  |  PDF »

Aggregation of Secreted Amyloid [IMAGE]-Protein into Sodium Dodecyl Sulfate-stable Oligomers in Cell Culture.

M. B. Podlisny, B. L. Ostaszewski, S. L. Squazzo, E. H. Koo, R. E. Rydell, D. B. Teplow, and D. J. Selkoe (1995)
J. Biol. Chem. 270, 9564-9570
 |  Abstract »  |  Full Text »  |  PDF »

Alzheimer's: could there be a zinc link?.

J Kaiser (1994)
Science 265, 1365
 |  PDF »

Evidence that the beta -Amyloid Plaques of Alzheimer's Disease Represent the Redox-silencing and Entombment of Abeta by Zinc.

M. P. Cuajungco, L. E. Goldstein, A. Nunomura, M. A. Smith, J. T. Lim, C. S. Atwood, X. Huang, Y. W. Farrag, G. Perry, and A. I. Bush (2000)
J. Biol. Chem. 275, 19439-19442
 |  Abstract »  |  Full Text »  |  PDF »

New Insights on How Metals Disrupt Amyloid beta -Aggregation and Their Effects on Amyloid-beta Cytotoxicity.

Y. Yoshiike, K. Tanemura, O. Murayama, T. Akagi, M. Murayama, S. Sato, X. Sun, N. Tanaka, and A. Takashima (2001)
J. Biol. Chem. 276, 32293-32299
 |  Abstract »  |  Full Text »  |  PDF »

Alzheimer's Disease Amyloid-beta Binds Copper and Zinc to Generate an Allosterically Ordered Membrane-penetrating Structure Containing Superoxide Dismutase-like Subunits.

C. C. Curtain, F. Ali, I. Volitakis, R. A. Cherny, R. S. Norton, K. Beyreuther, C. J. Barrow, C. L. Masters, A. I. Bush, and K. J. Barnham (2001)
J. Biol. Chem. 276, 20466-20473
 |  Abstract »  |  Full Text »  |  PDF »

Structural and Functional Characterization of the Zn(II) Site in Dimethylargininase-1 (DDAH-1) from Bovine Brain. Zn(II) RELEASE ACTIVATES DDAH-1.

M. Knipp, J. M. Charnock, C. D. Garner, and M. Vasak (2001)
J. Biol. Chem. 276, 40449-40456
 |  Abstract »  |  Full Text »  |  PDF »

Histochemically Reactive Zinc in Plaques of the Swedish Mutant {beta}-Amyloid Precursor Protein Transgenic Mice.

J.-Y. Lee, I. Mook-Jung, and J.-Y. Koh (1999)
J. Neurosci. 19, RC10
 |  Abstract »  |  Full Text »  |  PDF »

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