Science 2 September 1994: Vol. 265. no. 5177, pp. 1395 - 1400 DOI: 10.1126/science.8073282

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Articles

TCR Down-Regulation Controls T Cell Homeostasis.

L. Boding, C. M. Bonefeld, B. L. Nielsen, J. P. H. Lauritsen, M. R. von Essen, A. K. Hansen, J. M. Larsen, M. M. Nielsen, N. Odum, and C. Geisler (2009)
J. Immunol. 183, 4994-5005
 |  Abstract »  |  Full Text »  |  PDF »

A hassle a day may keep the pathogens away: The fight-or-flight stress response and the augmentation of immune function.

F. S. Dhabhar (2009)
Integr. Comp. Biol. 49, 215-236
 |  Abstract »  |  Full Text »  |  PDF »

Protective CD8 T Cell Memory Is Impaired during Chronic CD70-Driven Costimulation.

K. P. J. M. van Gisbergen, R. W. van Olffen, J. van Beek, K. F. van der Sluijs, R. Arens, M. A. Nolte, and R. A. van Lier (2009)
J. Immunol. 182, 5352-5362
 |  Abstract »  |  Full Text »  |  PDF »

Homeostatic Proliferation of Lymphocytes Results in Augmented Memory-Like Function and Accelerated Allograft Rejection.

V. F. Moxham, J. Karegli, R. E. Phillips, K. L. Brown, T. T. Tapmeier, R. Hangartner, S. H. Sacks, and W. Wong (2008)
J. Immunol. 180, 3910-3918
 |  Abstract »  |  Full Text »  |  PDF »

The Magnitude of the Antibody and Memory B Cell Responses during Priming with a Protein-Polysaccharide Conjugate Vaccine in Human Infants Is Associated with the Persistence of Antibody and the Intensity of Booster Response.

G. B. Rohner, M. D. Snape, D. F. Kelly, T. John, A. Morant, L.-M. Yu, A. Borkowski, F. Ceddia, R. Borrow, C.-A. Siegrist, et al. (2008)
J. Immunol. 180, 2165-2173
 |  Abstract »  |  Full Text »  |  PDF »

Comprehensive Assessment and Mathematical Modeling of T Cell Population Dynamics and Homeostasis.

V. Thomas-Vaslin, H. K. Altes, R. J. de Boer, and D. Klatzmann (2008)
J. Immunol. 180, 2240-2250
 |  Abstract »  |  Full Text »  |  PDF »

CD4+CD25int T Cells in Inflammatory Diseases Refractory to Treatment with Glucocorticoids.

R. W. J. Lee, T. J. Creed, L. P. Schewitz, P. V. Newcomb, L. B. Nicholson, A. D. Dick, and C. M. Dayan (2007)
J. Immunol. 179, 7941-7948
 |  Abstract »  |  Full Text »  |  PDF »

Persistent Antigen Presentation after Acute Vesicular Stomatitis Virus Infection.

D. L. Turner, L. S. Cauley, K. M. Khanna, and L. Lefrancois (2007)
J. Virol. 81, 2039-2046
 |  Abstract »  |  Full Text »  |  PDF »

CD27low CD4 T Lymphocytes That Accumulate in the Mouse Lungs during Mycobacterial Infection Differentiate from CD27high Precursors In Situ, Produce IFN-{gamma}, and Protect the Host against Tuberculosis Infection.

M. A. Kapina, G. S. Shepelkova, V. V. Mischenko, P. Sayles, P. Bogacheva, G. Winslow, A. S. Apt, and I. V. Lyadova (2007)
J. Immunol. 178, 976-985
 |  Abstract »  |  Full Text »  |  PDF »

Murine isolated lymphoid follicles contain follicular B lymphocytes with a mucosal phenotype.

C. Wang, K. G. McDonald, J. S. McDonough, and R. D. Newberry (2006)
Am J Physiol Gastrointest Liver Physiol 291, G595-G604
 |  Abstract »  |  Full Text »  |  PDF »

Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C.

T. Manigold, E.-C. Shin, E. Mizukoshi, K. Mihalik, K. K. Murthy, C. M. Rice, C. A. Piccirillo, and B. Rehermann (2006)
Blood 107, 4424-4432
 |  Abstract »  |  Full Text »  |  PDF »

Secondary memory CD8+ T cells are more protective but slower to acquire a central-memory phenotype.

A. Jabbari and J. T. Harty (2006)
J. Exp. Med. 203, 919-932
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus Type 1 Can Establish Latent Infection in Resting CD4+ T Cells in the Absence of Activating Stimuli.

W. J. Swiggard, C. Baytop, J. J. Yu, J. Dai, C. Li, R. Schretzenmair, T. Theodosopoulos, and U. O'Doherty (2005)
J. Virol. 79, 14179-14188
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Gene Therapy for Tolerance: B7 Signaling Is Required for Peptide-IgG Gene-Transferred Tolerance Induction.

M. T. Litzinger, Y. Su, T. C. Lei, N. Soukhareva, and D. W. Scott (2005)
J. Immunol. 175, 780-787
 |  Abstract »  |  Full Text »  |  PDF »

Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation.

K. Viswanathan and F. S. Dhabhar (2005)
PNAS 102, 5808-5813
 |  Abstract »  |  Full Text »  |  PDF »

Direct Cross-Priming by Th Lymphocytes Generates Memory Cytotoxic T Cell Responses.

R. Kennedy, A. H. Undale, W. C. Kieper, M. S. Block, L. R. Pease, and E. Celis (2005)
J. Immunol. 174, 3967-3977
 |  Abstract »  |  Full Text »  |  PDF »

Bone Marrow Microenvironmental Changes Underlie Reduced RAG-mediated Recombination and B Cell Generation in Aged Mice.

J. E. Labrie III, A. P. Sah, D. M. Allman, M. P. Cancro, and R. M. Gerstein (2004)
J. Exp. Med. 200, 411-423
 |  Abstract »  |  Full Text »  |  PDF »

De novo T-cell generation in patients at different ages and stages of HIV-1 disease.

M. Nobile, R. Correa, J. A. M. Borghans, C. D'Agostino, P. Schneider, R. J. de Boer, and G. Pantaleo (2004)
Blood 104, 470-477
 |  Abstract »  |  Full Text »  |  PDF »

IL-2 Induces a Competitive Survival Advantage in T Lymphocytes.

H. Dooms, E. Kahn, B. Knoechel, and A. K. Abbas (2004)
J. Immunol. 172, 5973-5979
 |  Abstract »  |  Full Text »  |  PDF »

B Cell-Dependent TCR Diversification.

C. Joao, B. M. Ogle, C. Gay-Rabinstein, J. L. Platt, and M. Cascalho (2004)
J. Immunol. 172, 4709-4716
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency of the Cyclin Kinase Inhibitor p21(WAF-1/CIP-1) Promotes Apoptosis of Activated/Memory T Cells and Inhibits Spontaneous Systemic Autoimmunity.

B. R. Lawson, R. Baccala, J. Song, M. Croft, D. H. Kono, and A. N. Theofilopoulos (2004)
J. Exp. Med. 199, 547-557
 |  Abstract »  |  Full Text »  |  PDF »

Photoperiod Influences the Effects of Exercise and Food Restriction on an Antigen-Specific Immune Response in Siberian Hamsters.

S. D. Bilbo and R. J. Nelson (2004)
Endocrinology 145, 556-564
 |  Abstract »  |  Full Text »  |  PDF »

Turning immunological memory into amnesia by depletion of dividing T cells.

B. Bellier, V. Thomas-Vaslin, M.-F. Saron, and D. Klatzmann (2003)
PNAS 100, 15017-15022
 |  Abstract »  |  Full Text »  |  PDF »

Leptin Induces Growth Hormone Secretion from Peripheral Blood Mononuclear Cells via a Protein Kinase C- and Nitric Oxide-Dependent Mechanism.

V. D. Dixit, M. Mielenz, D. D. Taub, and N. Parvizi (2003)
Endocrinology 144, 5595-5603
 |  Abstract »  |  Full Text »  |  PDF »

Sustained Response Initiation Is Required for T Cell Clonal Expansion But Not for Effector or Memory Development In Vivo.

L. Lefrancois, A. Marzo, and K. Williams (2003)
J. Immunol. 171, 2832-2839
 |  Abstract »  |  Full Text »  |  PDF »

Phosphatidylinositol 3-Kinase Regulates the CD4/CD8 T Cell Differentiation Ratio.

L. Rodriguez-Borlado, D. F. Barber, C. Hernandez, M. A. Rodriguez-Marcos, A. Sanchez, E. Hirsch, M. Wymann, C. Martinez-A., and A. C. Carrera (2003)
J. Immunol. 170, 4475-4482
 |  Abstract »  |  Full Text »  |  PDF »

Expression of a Constitutively Active Stat6 In Vivo Alters Lymphocyte Homeostasis with Distinct Effects in T and B Cells.

H. A. Bruns, U. Schindler, and M. H. Kaplan (2003)
J. Immunol. 170, 3478-3487
 |  Abstract »  |  Full Text »  |  PDF »

Pentoxifylline Functions As an Adjuvant In Vivo to Enhance T Cell Immune Responses by Inhibiting Activation-Induced Death.

R. Suresh, M. Vig, S. Bhatia, E. P. B. Goodspeed, B. John, U. Kandpal, S. Srivastava, A. George, R. Sen, V. Bal, et al. (2002)
J. Immunol. 169, 4262-4272
 |  Abstract »  |  Full Text »  |  PDF »

A Hassle a Day May Keep the Doctor Away: Stress and the Augmentation of Immune Function.

F. S. Dhabhar (2002)
Integr. Comp. Biol. 42, 556-564
 |  Abstract »  |  Full Text »  |  PDF »

Memory Functions and Death Proneness in Three CD4+CD45RO+ Human T Cell Subsets.

T. Ohara, K. Koyama, Y. Kusunoki, T. Hayashi, N. Tsuyama, Y. Kubo, and S. Kyoizumi (2002)
J. Immunol. 169, 39-48
 |  Abstract »  |  Full Text »  |  PDF »

Conversion of Naive T Cells to a Memory-Like Phenotype in Lymphopenic Hosts Is Not Related to a Homeostatic Mechanism That Fills the Peripheral Naive T Cell Pool.

C. Tanchot, A. Le Campion, B. Martin, S. Leaument, N. Dautigny, and B. Lucas (2002)
J. Immunol. 168, 5042-5046
 |  Abstract »  |  Full Text »  |  PDF »

Memorizing innate instructions requires a sufficiently specific adaptive immune system.

J. A. M. Borghans and R. J. De Boer (2002)
Int. Immunol. 14, 525-532
 |  Abstract »  |  Full Text »  |  PDF »

Naive T cells proliferate strongly in neonatal mice in response to self-peptide/self-MHC complexes.

A. Le Campion, C. Bourgeois, F. Lambolez, B. Martin, S. Leaument, N. Dautigny, C. Tanchot, C. Penit, and B. Lucas (2002)
PNAS 99, 4538-4543
 |  Abstract »  |  Full Text »  |  PDF »

Preexisting Inflammation Due to Mycobacterium bovis BCG Infection Differentially Modulates T-Cell Priming against a Replicating or Nonreplicating Immunogen.

R. Dudani, Y. Chapdelaine, H. van Faassen, D. K. Smith, H. Shen, L. Krishnan, and S. Sad (2002)
Infect. Immun. 70, 1957-1964
 |  Abstract »  |  Full Text »  |  PDF »

Short day lengths augment stress-induced leukocyte trafficking and stress-induced enhancement of skin immune function.

S. D. Bilbo, F. S. Dhabhar, K. Viswanathan, A. Saul, S. M. Yellon, and R. J. Nelson (2002)
PNAS 99, 4067-4072
 |  Abstract »  |  Full Text »  |  PDF »

Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naive and memory T cell compartments.

Q. Ge, H. Hu, H. N. Eisen, and J. Chen (2002)
PNAS 99, 2989-2994
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative and Qualitative Adjustment of Thymic T Cell Production by Clonal Expansion of Premigrant Thymocytes.

A. Le Campion, B. Lucas, N. Dautigny, S. Leaument, F. Vasseur, and C. Penit (2002)
J. Immunol. 168, 1664-1671
 |  Abstract »  |  Full Text »  |  PDF »

Aire deficient mice develop multiple features of APECED phenotype and show altered immune response.

C. Ramsey, O. Winqvist, L. Puhakka, M. Halonen, A. Moro, O. Kampe, P. Eskelin, M. Pelto-Huikko, and L. Peltonen (2002)
Hum. Mol. Genet. 11, 397-409
 |  Abstract »  |  Full Text »  |  PDF »

Aqueous Humor in Primary Open-Angle Glaucoma Contains an Increased Level of CD44S.

P. A. Knepper, C. S. K. Mayanil, W. Goossens, R. D. Wertz, C. Holgren, R. Ritch, and R. R. Allingham (2002)
Invest. Ophthalmol. Vis. Sci. 43, 133-139
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Secondary Lymphoid Organs Are Essential for Maintaining the CD4, But Not CD8, Naive T Cell Pool.

Z. Dai and F. G. Lakkis (2001)
J. Immunol. 167, 6711-6715
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Dynamically Distinct Subpopulations of T Lymphocytes That Are Differentially Affected by HIV.

J. A. Kovacs, R. A. Lempicki, I. A. Sidorov, J. W. Adelsberger, B. Herpin, J. A. Metcalf, I. Sereti, M. A. Polis, R. T. Davey, J. Tavel, et al. (2001)
J. Exp. Med. 194, 1731-1741
 |  Abstract »  |  Full Text »  |  PDF »

Cross-Reactivity between Hepatitis C Virus and Influenza A Virus Determinant-Specific Cytotoxic T Cells.

H. Wedemeyer, E. Mizukoshi, A. R. Davis, J. R. Bennink, and B. Rehermann (2001)
J. Virol. 75, 11392-11400
 |  Abstract »  |  Full Text »

Cutting Edge: Induction of Follicular Homing Precedes Effector Th Cell Development.

P. Schaerli, P. Loetscher, and B. Moser (2001)
J. Immunol. 167, 6082-6086
 |  Abstract »  |  Full Text »  |  PDF »

Neonatal thymectomy identifies two major pools of sessile and recirculating peripheral T cells which appear to be under separate homeostatic control.

C. P. Cunningham, W. G. Kimpton, A. Fernando, and R. N. P. Cahill (2001)
Int. Immunol. 13, 1351-1359
 |  Abstract »  |  Full Text »  |  PDF »

Extracellular Nicotinamide Adenine Dinucleotide Induces T Cell Apoptosis In Vivo and In Vitro.

Z.-X. Liu, O. Azhipa, S. Okamoto, S. Govindarajan, and G. Dennert (2001)
J. Immunol. 167, 4942-4947
 |  Abstract »  |  Full Text »  |  PDF »

Expansion of the Antigenic Repertoire of a Single T Cell Receptor upon T Cell Activation.

A. Amrani, P. Serra, J. Yamanouchi, J. D. Trudeau, R. Tan, J. F. Elliott, and P. Santamaria (2001)
J. Immunol. 167, 655-666
 |  Abstract »  |  Full Text »  |  PDF »

Enforced Expression of GATA-3 During T Cell Development Inhibits Maturation of CD8 Single-Positive Cells and Induces Thymic Lymphoma in Transgenic Mice.

M. C. Nawijn, R. Ferreira, G. M. Dingjan, O. Kahre, D. Drabek, A. Karis, F. Grosveld, and R. W. Hendriks (2001)
J. Immunol. 167, 715-723
 |  Abstract »  |  Full Text »  |  PDF »

The search for new vaccines against tuberculosis.

I. M. Orme (2001)
J. Leukoc. Biol. 70, 1-10
 |  Abstract »  |  Full Text »  |  PDF »

Extensive Somatic Microsatellite Mutations in Normal Human Tissue.

S. Vilkki, J.-L. Tsao, A. Loukola, M. Poyhonen, O. Vierimaa, R. Herva, L. A. Aaltonen, and D. Shibata (2001)
Cancer Res. 61, 4541-4544
 |  Abstract »  |  Full Text »  |  PDF »

CD4+Thy1- thymocytes with a Th-type 2 cytokine response.

D. M. Cerasoli, G. Kelsoe, and M. Sarzotti (2001)
Int. Immunol. 13, 75-83
 |  Abstract »  |  Full Text »  |  PDF »

Priming by Microbial Antigens from the Intestinal Flora Determines the Ability of CD4+ T Cells to Rapidly Secrete IL-4 in BALB/c Mice Infected with Leishmania major.

V. Julia, S. S. McSorley, L. Malherbe, J.-P. Breittmayer, F. Girard-Pipau, A. Beck, and N. Glaichenhaus (2000)
J. Immunol. 165, 5637-5645
 |  Abstract »  |  Full Text »  |  PDF »

Homeostatic T Cell Proliferation: How Far Can T Cells Be Activated to Self-Ligands?.

C. D. Surh and J. Sprent (2000)
J. Exp. Med. 192, 9-14
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{alpha}{beta}TCR+ Cells Are a Minimal Fraction of Peripheral CD8+ Pool in MHC Class I-Deficient Mice.

D. Nesic, F. R. Santori, and S. Vukmanovic (2000)
J. Immunol. 165, 1896-1901
 |  Abstract »  |  Full Text »  |  PDF »

Insulin-Like Growth Factor 1 Promotes Cord Blood T Cell Maturation and Inhibits Its Spontaneous and Phytohemagglutinin-Induced Apoptosis Through Different Mechanisms.

W. Tu, P.-T. Cheung, and Y.-L. Lau (2000)
J. Immunol. 165, 1331-1336
 |  Abstract »  |  Full Text »  |  PDF »

Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo.

L. R.-BORLADO, C. REDONDO, B. ALVAREZ, C. JIMENEZ, L. M. CRIADO, J. FLORES, M. A. R. MARCOS, C. MARTINEZ-A, D. BALOMENOS, and A. C. CARRERA (2000)
FASEB J 14, 895-903
 |  Abstract »  |  Full Text »

Disruption of T Cell Homeostasis in Mice Expressing a T Cell-Specific Dominant Negative Transforming Growth Factor {beta} II Receptor.

P. J. Lucas, S.-J. Kim, S. J. Melby, and R. E. Gress (2000)
J. Exp. Med. 191, 1187-1196
 |  Abstract »  |  Full Text »  |  PDF »

Comparative Pharmacodynamics of Keliximab and Clenoliximab in Transgenic Mice Bearing Human CD4.

A. Sharma, C. B. Davis, L. A. P. Tobia, D. C. Kwok, M. G. Tucci, E. R. Gore, D. J. Herzyk, and T. K. Hart (2000)
J. Pharmacol. Exp. Ther. 293, 33-41
 |  Abstract »  |  Full Text »

The role of antigen-independent persistence of memory cytotoxic T lymphocytes.

D. Wodarz, R. M. May, and M. A. Nowak (2000)
Int. Immunol. 12, 467-477
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Lymphoid Homeostasis by IL-2 Receptor Signals In Vivo.

D. T. M. Leung, S. Morefield, and D. M. Willerford (2000)
J. Immunol. 164, 3527-3534
 |  Abstract »  |  Full Text »  |  PDF »

Qualitative Changes Accompany Memory T Cell Generation: Faster, More Effective Responses at Lower Doses of Antigen.

P. R. Rogers, C. Dubey, and S. L. Swain (2000)
J. Immunol. 164, 2338-2346
 |  Abstract »  |  Full Text »  |  PDF »

CD4+ T-Cell Subsets That Mediate Immunological Memory to Mycobacterium tuberculosis Infection in Mice.

P. Andersen and B. Smedegaard (2000)
Infect. Immun. 68, 621-629
 |  Abstract »  |  Full Text »  |  PDF »

Antiviral B Cell Memory in the Absence of Mature Follicular Dendritic Cell Networks and Classical Germinal Centers in TNFR1-/- Mice.

U. Karrer, C. Lopez-Macias, A. Oxenius, B. Odermatt, M. F. Bachmann, U. Kalinke, H. Bluethmann, H. Hengartner, and R. M. Zinkernagel (2000)
J. Immunol. 164, 768-778
 |  Abstract »  |  Full Text »  |  PDF »

Selective Expansion of Cross-Reactive Cd8+ Memory T Cells by Viral Variants.

J. B.A.G. Haanen, M. C. Wolkers, A. M. Kruisbeek, and T. N.M. Schumacher (1999)
J. Exp. Med. 190, 1319-1328
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of T Cells in Paroxysmal Nocturnal Hemoglobinuria Provides Direct Evidence That Thymic T-Cell Production Declines With Age.

S. J. Richards, G. J. Morgan, and P. Hillmen (1999)
Blood 94, 2790-2799
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the Transcription Factor Lung Kruppel-Like Factor Is Regulated by Cytokines and Correlates with Survival of Memory T Cells In Vitro and In Vivo.

S. L. Schober, C. T. Kuo, K. S. Schluns, L. Lefrancois, J. M. Leiden, and S. C. Jameson (1999)
J. Immunol. 163, 3662-3667
 |  Abstract »  |  Full Text »  |  PDF »

Markers of Lymphocyte Homing Distinguish CD4 T Cell Subsets That Turn Over in Response to HIV-1 Infection in Humans.

R. L. Hengel, B. M. Jones, M. S. Kennedy, M. R. Hubbard, and J. S. McDougal (1999)
J. Immunol. 163, 3539-3548
 |  Abstract »  |  Full Text »  |  PDF »

Turnover of T Cells in Murine Gammaherpesvirus 68-Infected Mice.

A. M. Hamilton-Easton, J. P. Christensen, and P. C. Doherty (1999)
J. Virol. 73, 7866-7869
 |  Abstract »  |  Full Text »

A central role for thymic emigrants in peripheral T cell homeostasis.

S. P. Berzins, D. I. Godfrey, J. F. A. P. Miller, and R. L. Boyd (1999)
PNAS 96, 9787-9791
 |  Abstract »  |  Full Text »  |  PDF »

Cd4+ T Cell Division in Irradiated Mice Requires Peptides Distinct from Those Responsible for Thymic Selection.

J. Bender, T. Mitchell, J. Kappler, and P. Marrack (1999)
J. Exp. Med. 190, 367-374
 |  Abstract »  |  Full Text »  |  PDF »

On the Lifespan of Virgin T Lymphocytes.

F. Di Rosa, S. Ramaswamy, J. P. Ridge, and P. Matzinger (1999)
J. Immunol. 163, 1253-1257
 |  Abstract »  |  Full Text »  |  PDF »

Massive Activation-Induced Cell Death of Alloreactive T Cells With Apoptosis of Bystander Postthymic T Cells Prevents Immune Reconstitution in Mice With Graft-Versus-Host Disease.

S. Brochu, B. Rioux-Masse, J. Roy, D.-C. Roy, and C. Perreault (1999)
Blood 94, 390-400
 |  Abstract »  |  Full Text »  |  PDF »

Dichotomy between naive and memory CD4+ T cell responses to Fas engagement.

J. Desbarats, T. Wade, W. F. Wade, and M. K. Newell (1999)
PNAS 96, 8104-8109
 |  Abstract »  |  Full Text »  |  PDF »

Developmental Regulation of Lck Targeting to the CD8 Coreceptor Controls Signaling in Naive and Memory T Cells.

M. F. Bachmann, A. Gallimore, S. Linkert, V. Cerundolo, A. Lanzavecchia, M. Kopf, and A. Viola (1999)
J. Exp. Med. 189, 1521-1530
 |  Abstract »  |  Full Text »  |  PDF »

Memory CD44int CD8 T cells show increased proliferative responses and IFN-{gamma} production following antigenic challenge in vitro.

M. Pihlgren, C. Arpin, T. Walzer, M. Tomkowiak, A. Thomas, J. Marvel, and P. M. Dubois (1999)
Int. Immunol. 11, 699-706
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Stable Epigenetic Inheritance of Regional IFN-{gamma} Promoter Demethylation in CD44highCD8+ T Lymphocytes.

D. R. Fitzpatrick, K. M. Shirley, and A. Kelso (1999)
J. Immunol. 162, 5053-5057
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Mucosal Immunity by Inactivated Poliovirus Vaccine Is Dependent on Previous Mucosal Contact with Live Virus.

T. M. P. T. Herremans, J. H. J. Reimerink, A. M. Buisman, T. G. Kimman, and M. P. G. Koopmans (1999)
J. Immunol. 162, 5011-5018
 |  Abstract »  |  Full Text »  |  PDF »

Survival of Naive CD4 T Cells: Roles of Restricting Versus Selecting MHC Class II and Cytokine Milieu.

T. E. Boursalian and K. Bottomly (1999)
J. Immunol. 162, 3795-3801
 |  Abstract »  |  Full Text »  |  PDF »

Functional differences between memory and naive CD8 T cells.

B. K. Cho, C. Wang, S. Sugawa, H. N. Eisen, and J. Chen (1999)
PNAS 96, 2976-2981
 |  Abstract »  |  Full Text »  |  PDF »

B Cell Maintenance in Aged Mice Reflects Both Increased B Cell Longevity and Decreased B Cell Generation.

G. H. Kline, T. A. Hayden, and N. R. Klinman (1999)
J. Immunol. 162, 3342-3349
 |  Abstract »  |  Full Text »  |  PDF »

Maturation of CD4+ Lymphocytes in the Aged Microenvironment Results in a Memory-Enriched Population.

J. A. Timm and M. L. Thoman (1999)
J. Immunol. 162, 711-717
 |  Abstract »  |  Full Text »  |  PDF »

A Single Specific Amino Acid Residue in Peptide Antigens Is Sufficient to Activate Memory CTL: Potential Role of Cross-Reactive Peptides in Memory T Cell Maintenance.

E. Reali, R. Guerrini, M. Marastoni, R. Tomatis, M. Grazia Masucci, S. Traniello, and R. Gavioli (1999)
J. Immunol. 162, 106-113
 |  Abstract »  |  Full Text »  |  PDF »

IL-7-Dependent Extrathymic Expansion of CD45RA+ T Cells Enables Preservation of a Naive Repertoire.

M. Vieira, D. Soares, N. J. Borthwick, M. K. Maini, G. Janossy, M. Salmon, and A. N. Akbar (1998)
J. Immunol. 161, 5909-5917
 |  Abstract »  |  Full Text »  |  PDF »

CD4+ T Cells Prevent Spontaneous Experimental Autoimmune Encephalomyelitis in Anti-Myelin Basic Protein T Cell Receptor Transgenic Mice.

F. Van de Keere and S. Tonegawa (1998)
J. Exp. Med. 188, 1875-1882
 |  Abstract »  |  Full Text »  |  PDF »

Self-Restricted Dual Receptor Memory T Cells.

W. T. Lee, V. Shiledar-Baxi, G. M. Winslow, D. Mix, and D. B. Murphy (1998)
J. Immunol. 161, 4513-4519
 |  Abstract »  |  Full Text »  |  PDF »

Normal Thymic Selection of TCR Transgenic CD4 T Cells, but Impaired Survival in the Periphery Despite the Presence of Selecting MHC Molecules.

T. Barthlott, R. J. Wright, and B. Stockinger (1998)
J. Immunol. 161, 3992-3999
 |  Abstract »  |  Full Text »  |  PDF »

Resistance to Apoptosis and Elevated Expression of Bcl-2 in Clonally Expanded CD4+CD28- T Cells from Rheumatoid Arthritis Patients.

M. Schirmer, A. N. Vallejo, C. M. Weyand, and J. J. Goronzy (1998)
J. Immunol. 161, 1018-1025
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Methylation of the Interferon {gamma} (IFN-{gamma}) and Interleukin 3 (IL-3) Genes in Newly Activated Primary CD8+ T Lymphocytes: Regional IFN-{gamma} Promoter Demethylation and mRNA Expression Are Heritable in CD44highCD8+ T Cells.

D. R. Fitzpatrick, K. M. Shirley, L. E. McDonald, H. Bielefeldt-Ohmann, G. F. Kay, and A. Kelso (1998)
J. Exp. Med. 188, 103-117
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Renewal Rates, Telomerase, and Telomere Length Shortening.

R. J. De Boer and A. J. Noest (1998)
J. Immunol. 160, 5832-5837
 |  Abstract »  |  Full Text »  |  PDF »

The Role of the Thymus and Recent Thymic Migrants in the Maintenance of the Adult Peripheral Lymphocyte Pool.

S.P. Berzins, R.L. Boyd, and J.F.A.P. Miller (1998)
J. Exp. Med. 187, 1839-1848
 |  Abstract »  |  Full Text »  |  PDF »

Turnover of CD4+ and CD8+ T Lymphocytes in HIV-1 Infection as Measured by Ki-67 Antigen.

N. Sachsenberg, A. S. Perelson, S. Yerly, G. A. Schockmel, D. Leduc, B. Hirschel, and L. Perrin (1998)
J. Exp. Med. 187, 1295-1303
 |  Abstract »  |  Full Text »  |  PDF »

Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off.

L. V. Parijs and A. K. Abbas (1998)
Science 280, 243-248
 |  Abstract »  |  Full Text »

CD8+ Memory T Cells (CD44high, Ly-6C+) Are More Sensitive than Naive Cells (CD44low, Ly-6C-) to TCR/CD8 Signaling in Response to Antigen.

J. M. Curtsinger, D. C. Lins, and M. F. Mescher (1998)
J. Immunol. 160, 3236-3243
 |  Abstract »  |  Full Text »  |  PDF »

Lymphoid Reconstitution After Autologous PBSC Transplantation With FACS-Sorted CD34+ Hematopoietic Progenitors.

C. Bomberger, M. Singh-Jairam, G. Rodey, A. Guerriero, A. M. Yeager, W. H. Fleming, H. K. Holland, and E. K. Waller (1998)
Blood 91, 2588-2600
 |  Abstract »  |  Full Text »  |  PDF »

Rapid Turnover of T Lymphocytes in SIV-Infected Rhesus Macaques.

H. Mohri, S. Bonhoeffer, S. Monard, A. S. Perelson, and D. D. Ho (1998)
Science 279, 1223-1227
 |  Abstract »  |  Full Text »

Pre-Exposure to Oxidative Stress Decreases the Nuclear Factor-{kappa}B-Dependent Transcription in T Lymphocytes.

N. Lahdenpohja, K. Savinainen, and M. Hurme (1998)
J. Immunol. 160, 1354-1358
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge Commentary: Differential TCR Signaling and the Generation of Memory T Cells.

D. L. Farber (1998)
J. Immunol. 160, 535-539
 |  Abstract »  |  Full Text »  |  PDF »

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