Science 26 August 1994: Vol. 265. no. 5176, pp. 1237 - 1240 DOI: 10.1126/science.7520605

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Articles

Lethal Effect of CD3-Specific Antibody in Mice Deficient in TGF-{beta}1 by Uncontrolled Flu-Like Syndrome.

S. Perruche, P. Zhang, T. Maruyama, J. A. Bluestone, P. Saas, and W. Chen (2009)
J. Immunol. 183, 953-961
 |  Abstract »  |  Full Text »  |  PDF »

Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells.

C. E. von Allmen, N. Schmitz, M. Bauer, H. J. Hinton, M. O. Kurrer, R. B. Buser, M. Gwerder, S. Muntwiler, T. Sparwasser, R. R. Beerli, et al. (2009)
PNAS 106, 11673-11678
 |  Abstract »  |  Full Text »  |  PDF »

Primary High-Dose Murine Norovirus 1 Infection Fails To Protect from Secondary Challenge with Homologous Virus.

G. Liu, S. M. Kahan, Y. Jia, and S. M. Karst (2009)
J. Virol. 83, 6963-6968
 |  Abstract »  |  Full Text »  |  PDF »

Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population.

B. Blanco, J. A. Perez-Simon, L. I. Sanchez-Abarca, T. Caballero-Velazquez, S. Gutierrez-Cossio, P. Hernandez-Campo, M. Diez-Campelo, C. Herrero-Sanchez, C. Rodriguez-Serrano, C. Santamaria, et al. (2009)
Haematologica 94, 975-983
 |  Abstract »  |  Full Text »  |  PDF »

Restricted Autoantigen Recognition Associated with Deletional and Adaptive Regulatory Mechanisms.

J. A. Gebe, B. B. Yue, K. A. Unrath, B. A. Falk, and G. T. Nepom (2009)
J. Immunol. 183, 59-65
 |  Abstract »  |  Full Text »  |  PDF »

IL-21 ensures TGF-{beta}1-induced IgA isotype expression in mouse Peyer's patches.

G.-Y. Seo, J. Youn, and P.-H. Kim (2009)
J. Leukoc. Biol. 85, 744-750
 |  Abstract »  |  Full Text »  |  PDF »

Vaccination Route That Induces Transforming Growth Factor {beta} Production Fails To Elicit Protective Immunity against Leishmania donovani Infection.

S. Bhowmick, T. Mazumdar, and N. Ali (2009)
Infect. Immun. 77, 1514-1523
 |  Abstract »  |  Full Text »  |  PDF »

Alveolar Type II Epithelial Cells Present Antigen to CD4+ T Cells and Induce Foxp3+ Regulatory T Cells.

M. Gereke, S. Jung, J. Buer, and D. Bruder (2009)
Am. J. Respir. Crit. Care Med. 179, 344-355
 |  Abstract »  |  Full Text »  |  PDF »

The Surprising Discovery That TGF{beta} Specifically Induces the IgA Class Switch.

J. Stavnezer and J. Kang (2009)
J. Immunol. 182, 5-7
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In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure.

F. Meiler, J. Zumkehr, S. Klunker, B. Ruckert, C. A. Akdis, and M. Akdis (2008)
J. Exp. Med. 205, 2887-2898
 |  Abstract »  |  Full Text »  |  PDF »

CXCL12 (SDF-1{alpha}) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells.

M. Meiron, Y. Zohar, R. Anunu, G. Wildbaum, and N. Karin (2008)
J. Exp. Med. 205, 2643-2655
 |  Abstract »  |  Full Text »  |  PDF »

Transplantation Survival Is Maintained by Granzyme B+ Regulatory Cells and Adaptive Regulatory T Cells.

D. C. Gondek, V. DeVries, E. C. Nowak, L.-F. Lu, K. A. Bennett, Z. A. Scott, and R. J. Noelle (2008)
J. Immunol. 181, 4752-4760
 |  Abstract »  |  Full Text »  |  PDF »

Linked Suppression across an MHC-Mismatched Barrier in a Miniature Swine Kidney Transplantation Model.

A. D. Griesemer, J. C. LaMattina, M. Okumi, J. D. Etter, A. Shimizu, D. H. Sachs, and K. Yamada (2008)
J. Immunol. 181, 4027-4036
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Variants in T Helper Cell Type 1, 2 and 3 Pathways and Gastric Cancer Risk in a Polish Population.

R. Mahajan, E. M. El-Omar, J. Lissowska, P. Grillo, C. S. Rabkin, A. Baccarelli, M. Yeager, L. H. Sobin, W. Zatonski, S. J. Channock, et al. (2008)
Jpn. J. Clin. Oncol. 38, 626-633
 |  Abstract »  |  Full Text »  |  PDF »

The B Subunit of Escherichia coli Heat-Labile Enterotoxin Inhibits Th1 but Not Th17 Cell Responses in Established Experimental Autoimmune Uveoretinitis.

B. J. E. Raveney, C. Richards, M.-L. Aknin, D. A. Copland, B. R. Burton, E. Kerr, L. B. Nicholson, N. A. Williams, and A. D. Dick (2008)
Invest. Ophthalmol. Vis. Sci. 49, 4008-4017
 |  Abstract »  |  Full Text »  |  PDF »

CD4 T cells: fates, functions, and faults.

J. Zhu and W. E. Paul (2008)
Blood 112, 1557-1569
 |  Abstract »  |  Full Text »  |  PDF »

CD46-Induced Immunomodulatory CD4+ T Cells Express the Adhesion Molecule and Chemokine Receptor Pattern of Intestinal T Cells.

S. K. Alford, G. D. Longmore, W. F. Stenson, and C. Kemper (2008)
J. Immunol. 181, 2544-2555
 |  Abstract »  |  Full Text »  |  PDF »

Resolving the Conundrum of Islet Transplantation by Linking Metabolic Dysregulation, Inflammation, and Immune Regulation.

X. Huang, D. J. Moore, R. J. Ketchum, C. S. Nunemaker, B. Kovatchev, A. L. McCall, and K. L. Brayman (2008)
Endocr. Rev. 29, 603-630
 |  Abstract »  |  Full Text »  |  PDF »

Polyclonal Adaptive Regulatory CD4 Cells That Can Reverse Type I Diabetes Become Oligoclonal Long-Term Protective Memory Cells.

E. Godebu, D. Summers-Torres, M. M. Lin, B. J. G. Baaten, and L. M. Bradley (2008)
J. Immunol. 181, 1798-1805
 |  Abstract »  |  Full Text »  |  PDF »

Latency-Associated Peptide Identifies a Novel CD4+CD25+ Regulatory T Cell Subset with TGF{beta}-Mediated Function and Enhanced Suppression of Experimental Autoimmune Encephalomyelitis.

M.-L. Chen, B.-S. Yan, Y. Bando, V. K. Kuchroo, and H. L. Weiner (2008)
J. Immunol. 180, 7327-7337
 |  Abstract »  |  Full Text »  |  PDF »

IL-10: The Master Regulator of Immunity to Infection.

K. N. Couper, D. G. Blount, and E. M. Riley (2008)
J. Immunol. 180, 5771-5777
 |  Abstract »  |  Full Text »  |  PDF »

Low-Dose Tolerance Is Mediated by the Microfold Cell Ligand, Reovirus Protein {sigma}1.

A. Rynda, M. Maddaloni, D. Mierzejewska, J. Ochoa-Reparaz, T. Maslanka, K. Crist, C. Riccardi, B. Barszczewska, K. Fujihashi, J. R. McGhee, et al. (2008)
J. Immunol. 180, 5187-5200
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Adaptive T Regulatory Cells That Suppress the Allergic Response by Coimmunization of DNA and Protein Vaccines.

H. Jin, Y. Kang, L. Zhao, C. Xiao, Y. Hu, R. She, Y. Yu, X. Du, G. Zhao, T. Ng, et al. (2008)
J. Immunol. 180, 5360-5372
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Regulation of Experimental Autoimmune Encephalomyelitis by NK Cells: Alteration of Primary Adaptive Responses.

R. Winkler-Pickett, H. A. Young, J. M. Cherry, J. Diehl, J. Wine, T. Back, W. E. Bere, A. T. Mason, and J. R. Ortaldo (2008)
J. Immunol. 180, 4495-4506
 |  Abstract »  |  Full Text »  |  PDF »

Essential roles of TGF-{beta} in anti-CD3 antibody therapy: reversal of diabetes in nonobese diabetic mice independent of Foxp3+CD4+ regulatory T cells.

G. Chen, G. Han, J. Wang, R. Wang, R. Xu, B. Shen, J. Qian, and Y. Li (2008)
J. Leukoc. Biol. 83, 280-287
 |  Abstract »  |  Full Text »  |  PDF »

A regulatory role of interleukin 15 in wound healing and mucosal infection in mice.

Y. Kagimoto, H. Yamada, T. Ishikawa, N. Maeda, F. Goshima, Y. Nishiyama, M. Furue, and Y. Yoshikai (2008)
J. Leukoc. Biol. 83, 165-172
 |  Abstract »  |  Full Text »  |  PDF »

Developmental Exposure to Noninherited Maternal Antigens Induces CD4+ T Regulatory Cells: Relevance to Mechanism of Heart Allograft Tolerance.

M. L. Molitor-Dart, J. Andrassy, J. Kwun, H. A. Kayaoglu, D. A. Roenneburg, L. D. Haynes, J. R. Torrealba, J. L. Bobadilla, H. W. Sollinger, S. J. Knechtle, et al. (2007)
J. Immunol. 179, 6749-6761
 |  Abstract »  |  Full Text »  |  PDF »

Trans-Sialidase Recombinant Protein Mixed with CpG Motif-Containing Oligodeoxynucleotide Induces Protective Mucosal and Systemic Trypanosoma cruzi Immunity Involving CD8+ CTL and B Cell-Mediated Cross-Priming.

D. F. Hoft, C. S. Eickhoff, O. K. Giddings, J. R. C. Vasconcelos, and M. M. Rodrigues (2007)
J. Immunol. 179, 6889-6900
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40.

W. Niedbala, B. Cai, H. Liu, N. Pitman, L. Chang, and F. Y. Liew (2007)
PNAS 104, 15478-15483
 |  Abstract »  |  Full Text »  |  PDF »

NKT Cell-Derived Urokinase-Type Plasminogen Activator Promotes Peripheral Tolerance Associated with Eye.

K.-H. Sonoda, T. Nakamura, H. A. Young, D. Hart, P. Carmeliet, and J. Stein-Streilein (2007)
J. Immunol. 179, 2215-2222
 |  Abstract »  |  Full Text »  |  PDF »

IL-10 Is Excluded from the Functional Cytokine Memory of Human CD4+ Memory T Lymphocytes.

J. Dong, C. Ivascu, H.-D. Chang, P. Wu, R. Angeli, L. Maggi, F. Eckhardt, L. Tykocinski, C. Haefliger, B. Mowes, et al. (2007)
J. Immunol. 179, 2389-2396
 |  Abstract »  |  Full Text »  |  PDF »

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid.

C.-M. Sun, J. A. Hall, R. B. Blank, N. Bouladoux, M. Oukka, J. R. Mora, and Y. Belkaid (2007)
J. Exp. Med. 204, 1775-1785
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Autoimmune Diabetes by Oral Administration of Anti-CD3 Monoclonal Antibody.

H. Ishikawa, H. Ochi, M.-L. Chen, D. Frenkel, R. Maron, and H. L. Weiner (2007)
Diabetes 56, 2103-2109
 |  Abstract »  |  Full Text »  |  PDF »

HLA-G expression defines a novel regulatory T-cell subset present in human peripheral blood and sites of inflammation.

U. Feger, E. Tolosa, Y.-H. Huang, A. Waschbisch, T. Biedermann, A. Melms, and H. Wiendl (2007)
Blood 110, 568-577
 |  Abstract »  |  Full Text »  |  PDF »

IL-10 Regulates Movement of Intestinally Derived CD4+ T Cells to the Liver.

S. K. Bliss, S. P. Bliss, D. P. Beiting, A. Alcaraz, and J. A. Appleton (2007)
J. Immunol. 178, 7974-7983
 |  Abstract »  |  Full Text »  |  PDF »

Intestinal epithelial cells from inflammatory bowel disease patients preferentially stimulate CD4+ T cells to proliferate and secrete interferon-{gamma}.

I. Dotan, M. Allez, A. Nakazawa, J. Brimnes, M. Schulder-Katz, and L. Mayer (2007)
Am J Physiol Gastrointest Liver Physiol 292, G1630-G1640
 |  Abstract »  |  Full Text »  |  PDF »

Minimally Activated CD8 Autoreactive T Cells Specific for IRBP Express a High Level of Foxp3 and Are Functionally Suppressive.

Y. Peng, H. Shao, Y. Ke, P. Zhang, G. Han, H. J. Kaplan, and D. Sun (2007)
Invest. Ophthalmol. Vis. Sci. 48, 2178-2184
 |  Abstract »  |  Full Text »  |  PDF »

Immunopathogenesis of IBD: insufficient suppressor function in the gut?.

I L Huibregtse, A U van Lent, and S J H van Deventer (2007)
Gut 56, 584-592
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TGF-beta1-Mediated Control of Central Nervous System Inflammation and Autoimmunity through the Inhibitory Receptor CD26.

V. Preller, A. Gerber, S. Wrenger, M. Togni, D. Marguet, J. Tadje, U. Lendeckel, C. Rocken, J. Faust, K. Neubert, et al. (2007)
J. Immunol. 178, 4632-4640
 |  Abstract »  |  Full Text »  |  PDF »

Role of Naturally Occurring CD4+CD25+ Regulatory T Cells in Experimental Atherosclerosis.

A. Mor, D. Planer, G. Luboshits, A. Afek, S. Metzger, T. Chajek-Shaul, G. Keren, and J. George (2007)
Arterioscler. Thromb. Vasc. Biol. 27, 893-900
 |  Abstract »  |  Full Text »  |  PDF »

Th3 Cells in Peripheral Tolerance. II. TGF-beta-Transgenic Th3 Cells Rescue IL-2-Deficient Mice from Autoimmunity.

Y. Carrier, J. Yuan, V. K. Kuchroo, and H. L. Weiner (2007)
J. Immunol. 178, 172-178
 |  Abstract »  |  Full Text »  |  PDF »

Th3 Cells in Peripheral Tolerance. I. Induction of Foxp3-Positive Regulatory T Cells by Th3 Cells Derived from TGF-beta T Cell-Transgenic Mice.

Y. Carrier, J. Yuan, V. K. Kuchroo, and H. L. Weiner (2007)
J. Immunol. 178, 179-185
 |  Abstract »  |  Full Text »  |  PDF »

A Regulatory CD4+ T Cell Subset in the BB Rat Model of Autoimmune Diabetes Expresses Neither CD25 Nor Foxp3.

J.-L. Hillebrands, B. Whalen, J. T. J. Visser, J. Koning, K. D. Bishop, J. Leif, J. Rozing, J. P. Mordes, D. L. Greiner, and A. A. Rossini (2006)
J. Immunol. 177, 7820-7832
 |  Abstract »  |  Full Text »  |  PDF »

Coadministration of Plasmid DNA Constructs Encoding an Encephalitogenic Determinant and IL-10 Elicits Regulatory T Cell-Mediated Protective Immunity in the Central Nervous System.

S. Schif-Zuck, G. Wildbaum, and N. Karin (2006)
J. Immunol. 177, 8241-8247
 |  Abstract »  |  Full Text »  |  PDF »

Role of nitric oxide in the regulation of T cell functions.

W Niedbala, B Cai, and F Y Liew (2006)
Ann Rheum Dis 65, iii37-iii40
 |  Abstract »  |  Full Text »  |  PDF »

Heat shock proteins induce T cell regulation of chronic inflammation.

F Hauet-Broere, L Wieten, T Guichelaar, S Berlo, R van der Zee, and W Van Eden (2006)
Ann Rheum Dis 65, iii65-iii68
 |  Abstract »  |  Full Text »  |  PDF »

Dysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice.

P. J. Lucas, S.-J. Kim, C. L. Mackall, W. G. Telford, Y.-W. Chu, F. T. Hakim, and R. E. Gress (2006)
Blood 108, 2789-2795
 |  Abstract »  |  Full Text »  |  PDF »

Human CD4+ T lymphocytes with increased intracellular cAMP levels exert regulatory functions by releasing extracellular cAMP.

S. Vendetti, M. Patrizio, A. Riccomi, and M. T. De Magistris (2006)
J. Leukoc. Biol. 80, 880-888
 |  Abstract »  |  Full Text »  |  PDF »

Gliadin-Specific Type 1 Regulatory T Cells from the Intestinal Mucosa of Treated Celiac Patients Inhibit Pathogenic T Cells.

C. Gianfrani, M. K. Levings, C. Sartirana, G. Mazzarella, G. Barba, D. Zanzi, A. Camarca, G. Iaquinto, N. Giardullo, S. Auricchio, et al. (2006)
J. Immunol. 177, 4178-4186
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory T Cells, a Potent Immunoregulatory Target for CAM Researchers: Modulating Tumor Immunity, Autoimmunity and Alloreactive Immunity (III).

A. Vojdani and J. Erde (2006)
Evid. Based Complement. Altern. Med. 3, 309-316
 |  Abstract »  |  Full Text »  |  PDF »

CD103 Is a Marker for Alloantigen-Induced Regulatory CD8+ T Cells..

E. Uss, A. T. Rowshani, B. Hooibrink, N. M. Lardy, R. A. W. van Lier, and I. J. M. ten Berge (2006)
J. Immunol. 177, 2775-2783
 |  Abstract »  |  Full Text »  |  PDF »

FOXP3+CD4+CD25+ Adaptive Regulatory T Cells Express Cyclooxygenase-2 and Suppress Effector T Cells by a Prostaglandin E2-Dependent Mechanism.

M. Mahic, S. Yaqub, C. C. Johansson, K. Tasken, and E. M. Aandahl (2006)
J. Immunol. 177, 246-254
 |  Abstract »  |  Full Text »  |  PDF »

Emerging possibilities in the development and function of regulatory T cells.

K. Wing, Z. Fehervari, and S. Sakaguchi (2006)
Int. Immunol. 18, 991-1000
 |  Abstract »  |  Full Text »  |  PDF »

ERK1-/- Mice Exhibit Th1 Cell Polarization and Increased Susceptibility to Experimental Autoimmune Encephalomyelitis.

A. Agrawal, S. Dillon, T. L. Denning, and B. Pulendran (2006)
J. Immunol. 176, 5788-5796
 |  Abstract »  |  Full Text »  |  PDF »

Toll-like receptor 2 signaling modulates the functions of CD4+CD25+ regulatory T cells.

H. Liu, M. Komai-Koma, D. Xu, and F. Y. Liew (2006)
PNAS 103, 7048-7053
 |  Abstract »  |  Full Text »  |  PDF »

Antigen-Induced IL-10+ Regulatory T Cells Are Independent of CD25+ Regulatory Cells for Their Growth, Differentiation, and Function.

K. S. Nicolson, E. J. O'Neill, A. Sundstedt, H. B. Streeter, S. Minaee, and D. C. Wraith (2006)
J. Immunol. 176, 5329-5337
 |  Abstract »  |  Full Text »  |  PDF »

Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways.

A. Tedgui and Z. Mallat (2006)
Physiol Rev 86, 515-581
 |  Abstract »  |  Full Text »  |  PDF »

Recovery from experimental allergic encephalomyelitis is TGF-{beta} dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells.

X. Zhang, J. Reddy, H. Ochi, D. Frenkel, V. K. Kuchroo, and H. L. Weiner (2006)
Int. Immunol. 18, 495-503
 |  Abstract »  |  Full Text »  |  PDF »

IL-7 Is a Critical Factor in Modulating Lesion Development in Skn-Directed Autoimmunity.

P. J. Staton, A. B. Carpenter, and S. H. Jackman (2006)
J. Immunol. 176, 3978-3986
 |  Abstract »  |  Full Text »  |  PDF »

Inhalation Tolerance Is Induced Selectively in Thoracic Lymph Nodes but Executed Pervasively at Distant Mucosal and Nonmucosal Tissues.

D. Alvarez, F. K. Swirski, T.-C. Yang, R. Fattouh, K. Croitoru, J. L. Bramson, M. R. Stampfli, and M. Jordana (2006)
J. Immunol. 176, 2568-2580
 |  Abstract »  |  Full Text »  |  PDF »

B Cells Are Crucial for Determinant Spreading of T Cell Autoimmunity among beta Cell Antigens in Diabetes-Prone Nonobese Diabetic Mice.

J. Tian, D. Zekzer, Y. Lu, H. Dang, and D. L. Kaufman (2006)
J. Immunol. 176, 2654-2661
 |  Abstract »  |  Full Text »  |  PDF »

Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation.

W. Barchet, J. D. Price, M. Cella, M. Colonna, S. K. MacMillan, J. P. Cobb, P. A. Thompson, K. M. Murphy, J. P. Atkinson, and C. Kemper (2006)
Blood 107, 1497-1504
 |  Abstract »  |  Full Text »  |  PDF »

Splenic Dendritic Cells Induced by Oral Antigen Administration Are Important for the Transfer of Oral Tolerance in an Experimental Model of Asthma.

K. Nagatani, M. Dohi, Y. To, R. Tanaka, K. Okunishi, K. Nakagome, K. Sagawa, Y. Tanno, Y. Komagata, and K. Yamamoto (2006)
J. Immunol. 176, 1481-1489
 |  Abstract »  |  Full Text »  |  PDF »

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host.

B. Huang, P.-Y. Pan, Q. Li, A. I. Sato, D. E. Levy, J. Bromberg, C. M. Divino, and S.-H. Chen (2006)
Cancer Res. 66, 1123-1131
 |  Abstract »  |  Full Text »  |  PDF »

A Case for Regulatory B Cells.

A. Mizoguchi and A. K. Bhan (2006)
J. Immunol. 176, 705-710
 |  Abstract »  |  Full Text »  |  PDF »

The ICOS Molecule Plays a Crucial Role in the Development of Mucosal Tolerance.

K. Miyamoto, C. I. Kingsley, X. Zhang, C. Jabs, L. Izikson, R. A. Sobel, H. L. Weiner, V. K. Kuchroo, and A. H. Sharpe (2005)
J. Immunol. 175, 7341-7347
 |  Abstract »  |  Full Text »  |  PDF »

A Live Diarrheal Vaccine Imprints a Th2 Cell Bias and Acts as an Anti-Inflammatory Vaccine.

S. Jun, W. Gilmore, G. Callis, A. Rynda, A. Haddad, and D. W. Pascual (2005)
J. Immunol. 175, 6733-6740
 |  Abstract »  |  Full Text »  |  PDF »

Selective Modulation of CD4+ T Cells from Lupus Patients by a Promiscuous, Protective Peptide Analog.

F. Monneaux, J. Hoebeke, C. Sordet, C. Nonn, J.-P. Briand, B. Maillere, J. Sibillia, and S. Muller (2005)
J. Immunol. 175, 5839-5847
 |  Abstract »  |  Full Text »  |  PDF »

Toll-like receptor 2 signalling and inflammation.

F Y Liew, M Patel, and D Xu (2005)
Ann Rheum Dis 64, iv104-iv105
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Dendritic cells differentiated in the presence of IFN-{beta} and IL-3 are potent inducers of an antigen-specific CD8+ T cell response.

K. Breckpot, J. Corthals, A. Bonehill, A. Michiels, S. Tuyaerts, C. Aerts, C. Heirman, and K. Thielemans (2005)
J. Leukoc. Biol. 78, 898-908
 |  Abstract »  |  Full Text »  |  PDF »

CD4+ regulatory cells as a potential immunotherapy.

Z. Fehervari and S. Sakaguchi (2005)
Phil Trans R Soc B 360, 1647-1661
 |  Abstract »  |  Full Text »  |  PDF »

Treatment of Passive Experimental Autoimmune Encephalomyelitis in SJL Mice with a Recombinant TCR Ligand Induces IL-13 and Prevents Axonal Injury.

H. Offner, S. Subramanian, C. Wang, M. Afentoulis, A. A. Vandenbark, J. Huan, and G. G. Burrows (2005)
J. Immunol. 175, 4103-4111
 |  Abstract »  |  Full Text »  |  PDF »

Stat4-null non-obese diabetic mice: protection from diabetes and experimental allergic encephalomyelitis, but with concomitant epitope spread.

R. J. Boyton, S. Davies, C. Marden, C. Fantino, C. Reynolds, K. Portugal, H. Dewchand, and D. M. Altmann (2005)
Int. Immunol. 17, 1157-1165
 |  Abstract »  |  Full Text »  |  PDF »

Type 1 Immunity Provides Both Optimal Mucosal and Systemic Protection against a Mucosally Invasive, Intracellular Pathogen.

D. F. Hoft and C. S. Eickhoff (2005)
Infect. Immun. 73, 4934-4940
 |  Abstract »  |  Full Text »  |  PDF »

Orally Tolerized T Cells Can Form Conjugates with APCs but Are Defective in Immunological Synapse Formation.

W. Ise, K. Nakamura, N. Shimizu, H. Goto, K. Fujimoto, S. Kaminogawa, and S. Hachimura (2005)
J. Immunol. 175, 829-838
 |  Abstract »  |  Full Text »  |  PDF »

Protection against Experimental Autoimmune Myocarditis Is Mediated by Interleukin-10-Producing T Cells that Are Controlled by Dendritic Cells.

Y. Li, J. S. Heuser, S. D. Kosanke, M. Hemric, and M. W. Cunningham (2005)
Am. J. Pathol. 167, 5-15
 |  Abstract »  |  Full Text »  |  PDF »

TLR2 Agonist Ameliorates Established Allergic Airway Inflammation by Promoting Th1 Response and Not via Regulatory T Cells.

M. Patel, D. Xu, P. Kewin, B. Choo-Kang, C. McSharry, N. C. Thomson, and F. Y. Liew (2005)
J. Immunol. 174, 7558-7563
 |  Abstract »  |  Full Text »  |  PDF »

CD27/CFSE-Based Ex Vivo Selection of Highly Suppressive Alloantigen-Specific Human Regulatory T Cells.

H. J. P. M. Koenen, E. Fasse, and I. Joosten (2005)
J. Immunol. 174, 7573-7583
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In Vivo IL-10 Gene Delivery Suppresses Airway Eosinophilia and Hyperreactivity by Down-Regulating APC Functions and Migration without Impairing the Antigen-Specific Systemic Immune Response in a Mouse Model of Allergic Airway Inflammation.

K. Nakagome, M. Dohi, K. Okunishi, Y. Komagata, K. Nagatani, R. Tanaka, J.-i. Miyazaki, and K. Yamamoto (2005)
J. Immunol. 174, 6955-6966
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Defects in CD8+ Regulatory T Cells in the Lamina Propria of Patients with Inflammatory Bowel Disease.

J. Brimnes, M. Allez, I. Dotan, L. Shao, A. Nakazawa, and L. Mayer (2005)
J. Immunol. 174, 5814-5822
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Preventing Intolerance: The Induction of Nonresponsiveness to Dietary and Microbial Antigens in the Intestinal Mucosa.

D. W. Smith and C. Nagler-Anderson (2005)
J. Immunol. 174, 3851-3857
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Targeted Overexpression of IL-18 Binding Protein at the Central Nervous System Overrides Flexibility in Functional Polarization of Antigen-Specific Th2 Cells.

S. Schif-Zuck, J. Westermann, N. Netzer, Y. Zohar, M. Meiron, G. Wildbaum, and N. Karin (2005)
J. Immunol. 174, 4307-4315
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Isolation and characterization of human antigen-specific TCR{alpha}{beta}+ CD4-CD8- double-negative regulatory T cells.

K. Fischer, S. Voelkl, J. Heymann, G. K. Przybylski, K. Mondal, M. Laumer, L. Kunz-Schughart, C. A. Schmidt, R. Andreesen, and A. Mackensen (2005)
Blood 105, 2828-2835
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De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells.

M. R. Walker, B. D. Carson, G. T. Nepom, S. F. Ziegler, and J. H. Buckner (2005)
PNAS 102, 4103-4108
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Clinical Effects of Lactobacillus acidophilus Strain L-92 on Perennial Allergic Rhinitis: A Double-Blind, Placebo-Controlled Study.

Y. Ishida, F. Nakamura, H. Kanzato, D. Sawada, H. Hirata, A. Nishimura, O. Kajimoto, and S. Fujiwara (2005)
J Dairy Sci 88, 527-533
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IL-2 Overcomes the Unresponsiveness but Fails to Reverse the Regulatory Function of Antigen-Induced T Regulatory Cells.

P. O. Anderson, A. Sundstedt, Z. Yazici, S. Minaee, R. Woolf, K. Nicolson, N. Whitley, L. Li, S. Li, D. C. Wraith, et al. (2005)
J. Immunol. 174, 310-319
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Differential Activation of ERK, p38, and JNK Required for Th1 and Th2 Deviation in Myelin-Reactive T Cells Induced by Altered Peptide Ligand.

R. A. K. Singh and J. Z. Zhang (2004)
J. Immunol. 173, 7299-7307
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Suppression of Ongoing Experimental Autoimmune Encephalomyelitis by Neutralizing the Function of the p28 Subunit of IL-27.

R. Goldberg, Y. Zohar, G. Wildbaum, Y. Geron, G. Maor, and N. Karin (2004)
J. Immunol. 173, 6465-6471
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Reduction of Retrovirus-Induced Immunosuppression by In Vivo Modulation of T Cells during Acute Infection.

H. He, R. J. Messer, S. Sakaguchi, G. Yang, S. J. Robertson, and K. J. Hasenkrug (2004)
J. Virol. 78, 11641-11647
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Induction of a CD4+ T Regulatory Type 1 Response by Cyclooxygenase-2-Overexpressing Glioma.

Y. Akasaki, G. Liu, N. H. C. Chung, M. Ehtesham, K. L. Black, and J. S. Yu (2004)
J. Immunol. 173, 4352-4359
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From the Cover: Delayed neuropathology after carbon monoxide poisoning is immune-mediated.

S. R. Thom, V. M. Bhopale, D. Fisher, J. Zhang, and P. Gimotty (2004)
PNAS 101, 13660-13665
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Suppressor T Cells in Human Diseases.

C. Baecher-Allan and D. A. Hafler (2004)
J. Exp. Med. 200, 273-276
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CD8 + T cells reduce in vitro interferon-g production in Theiler's murine encephalomyelitis virus-induced demyelinating disease model.

P. W Denton, C. M Tello, and R. W Melvold (2004)
Multiple Sclerosis 10, 370-375
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Regulation: the art of control? Regulatory T cells and asthma and allergy.

D S Robinson (2004)
Thorax 59, 640-643
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Suppression of Ongoing Adjuvant-Induced Arthritis by Neutralizing the Function of the p28 Subunit of IL-27.

R. Goldberg, G. Wildbaum, Y. Zohar, G. Maor, and N. Karin (2004)
J. Immunol. 173, 1171-1178
 |  Abstract »  |  Full Text »  |  PDF »

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