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Science 1 July 1994:
Vol. 265. no. 5168, pp. 53 - 60
DOI: 10.1126/science.8016655
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Articles

Science, Vol 265, Issue 5168, 53-60
Copyright © 1994 by American Association for the Advancement of Science

articles

Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex

J Cote, J Quinn, JL Workman, and CL Peterson

Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park 16802.

The SWI/SNF protein complex is required for the enhancement of transcription by many transcriptional activators in yeast. Here it is shown that the purified SWI/SNF complex is composed of 10 subunits and includes the SWI1, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products. The complex exhibited DNA-stimulated adenosine triphosphatase (ATPase) activity, but lacked helicase activity. The SWI/SNF complex caused a 10- to 30-fold stimulation in the binding of GAL4 derivatives to nucleosomal DNA in a reaction that required adenosine triphosphate (ATP) hydrolysis but was activation domain-independent. Stimulation of GAL4 binding by the complex was abolished by a mutant SWI2 subunit, and was increased by the presence of a histone-binding protein, nucleoplasmin. A direct ATP-dependent interaction between the SWI/SNF complex and nucleosomal DNA was detected. These observations suggest that a primary role of the SWI/SNF complex is to promote activator binding to nucleosomal DNA.


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ATP-dependent remodeling and acetylation as regulators of chromatin fluidity.
R. E. Kingston and G. J. Narlikar (1999)
Genes & Dev. 13, 2339-2352
   Full Text »
Recruitment of the SWI/SNF chromatin remodeling complex by transcriptional activators.
N. Yudkovsky, C. Logie, S. Hahn, and C. L. Peterson (1999)
Genes & Dev. 13, 2369-2374
   Abstract »    Full Text »
Identification of a Novel SNF2/SWI2 Protein Family Member, SRCAP, Which Interacts with CREB-binding Protein.
H. Johnston, J. Kneer, I. Chackalaparampil, P. Yaciuk, and J. Chrivia (1999)
J. Biol. Chem. 274, 16370-16376
   Abstract »    Full Text »    PDF »
Nuclear Receptor Coregulators: Cellular and Molecular Biology.
N. J. McKenna, R. B. Lanz, and B. W. O’Malley (1999)
Endocr. Rev. 20, 321-344
   Abstract »    Full Text »
Cell cycle-regulated histone acetylation required for expression of the yeast HO gene.
J. E. Krebs, M.-H. Kuo, C. D. Allis, and C. L. Peterson (1999)
Genes &