Science 1 July 1994: Vol. 265. no. 5168, pp. 106 - 109 DOI: 10.1126/science.8016643

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Articles

Role of Plasmacytoid Dendritic Cells for Aberrant Class II Expression in Exocrine Glands from Estrogen-Deficient Mice of Healthy Background.

R. Arakaki, A. Nagaoka, N. Ishimaru, A. Yamada, S. Yoshida, and Y. Hayashi (2009)
Am. J. Pathol. 174, 1715-1724
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Major Histocompatibility Class II Transactivator Expression in Smooth Muscle Cells from A2b Adenosine Receptor Knock-out Mice: CROSS-TALK BETWEEN THE ADENOSINE AND INTERFERON-{gamma} SIGNALING.

Y. Xu, K. Ravid, and B. D. Smith (2008)
J. Biol. Chem. 283, 14213-14220
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The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions.

P. Majumder, J. A. Gomez, B. P. Chadwick, and J. M. Boss (2008)
J. Exp. Med. 205, 785-798
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Mitogen-activated Protein Kinase ERK1/2 Regulates the Class II Transactivator.

L. N. Voong, A. R. Slater, S. Kratovac, and D. E. Cressman (2008)
J. Biol. Chem. 283, 9031-9039
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Down-Regulation of MHC II in Mesenchymal Stem Cells at High IFN-{gamma} Can Be Partly Explained by Cytoplasmic Retention of CIITA.

K. C. Tang, K. A. Trzaska, S. V. Smirnov, S. V. Kotenko, S. K. Schwander, J. J. Ellner, and P. Rameshwar (2008)
J. Immunol. 180, 1826-1833
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CIITA Mediates Interferon-{gamma} Repression of Collagen Transcription through Phosphorylation-dependent Interactions with Co-repressor Molecules.

Y. Xu, J. A. Harton, and B. D. Smith (2008)
J. Biol. Chem. 283, 1243-1256
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GTP-dependent Recruitment of CIITA to the Class II Major Histocompatibility Complex Promoter.

N. N. Bewry, S. C. E. Bolick, K. L. Wright, and J. A. Harton (2007)
J. Biol. Chem. 282, 26178-26184
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Genome-wide analysis of PPAR{alpha} activation in murine small intestine.

M. Bunger, H. M. van den Bosch, J. van der Meijde, S. Kersten, G. J. E. J. Hooiveld, and M. Muller (2007)
Physiol Genomics 30, 192-204
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Controlling the Ir Genes.

J. M. Boss (2007)
J. Immunol. 178, 6675-6676
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Minocycline Down-regulates MHC II Expression in Microglia and Macrophages through Inhibition of IRF-1 and Protein Kinase C (PKC){alpha}/betaII.

M. Nikodemova, J. J. Watters, S. J. Jackson, S. K. Yang, and I. D. Duncan (2007)
J. Biol. Chem. 282, 15208-15216
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Dynamic Changes in Pro- and Anti-Inflammatory Cytokine Profiles and Gamma Interferon Receptor Signaling Integrity Correlate with Tuberculosis Disease Activity and Response to Curative Treatment.

E. Sahiratmadja, B. Alisjahbana, T. de Boer, I. Adnan, A. Maya, H. Danusantoso, R. H. H. Nelwan, S. Marzuki, J. W. M. van der Meer, R. van Crevel, et al. (2007)
Infect. Immun. 75, 820-829
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Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis.

S. Kanazawa, S. Ota, C. Sekine, T. Tada, T. Otsuka, T. Okamoto, G. Sonderstrup, and B. M. Peterlin (2006)
PNAS 103, 14465-14470
 |  Abstract »  |  Full Text »  |  PDF »

Epigenetic Regulation during B Cell Differentiation Controls CIITA Promoter Accessibility.

M. R. Green, H. Yoon, and J. M. Boss (2006)
J. Immunol. 177, 3865-3873
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Pravastatin prolongs graft survival in an allogeneic rat model of orthotopic single lung transplantation..

Y. Li, T. Koster, C. Morike, S. v. Horsten, U. Martin, M. Bader, A. Haverich, and A. R. Simon (2006)
Eur. J. Cardiothorac. Surg. 30, 515-524
 |  Abstract »  |  Full Text »  |  PDF »

ERK and p38 MAPK Signaling Pathways Negatively Regulate CIITA Gene Expression in Dendritic Cells and Macrophages.

Y. Yao, Q. Xu, M.-J. Kwon, R. Matta, Y. Liu, S.-C. Hong, and C.-H. Chang (2006)
J. Immunol. 177, 70-76
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Self-Antigen Maintains the Innate Antibacterial Function of Self-Specific CD8 T Cells In Vivo.

S. Dhanji, M. T. Chow, and H.-S. Teh (2006)
J. Immunol. 177, 138-146
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Presence and regulation of messenger ribonucleic acids encoding components of the class II major histocompatibility complex-associated antigen processing pathway in the bovine corpus luteum..

M. J Cannon, J. S Davis, and J. L Pate (2006)
Reproduction 131, 689-698
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MHC class II expression through a hitherto unknown pathway supports T helper cell-dependent immune responses: implications for MHC class II deficiency.

T. Buch, B. Polic, B. E. Clausen, S. Weiss, O. Akilli-Ozturk, C.-H. Chang, R. Flavell, A. Schulz, S. Jonjic, A. Waisman, et al. (2006)
Blood 107, 1434-1444
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Cells Transduced with the MHC Class II Transactivator and CD80 Activate Tumor-Specific CD4+ T Cells Whether or Not They Are Silenced for Invariant Chain.

J. A. Thompson, S. K. Dissanayake, B. R. Ksander, K. L. Knutson, M. L. Disis, and S. Ostrand-Rosenberg (2006)
Cancer Res. 66, 1147-1154
 |  Abstract »  |  Full Text »  |  PDF »

Mycobacterium bovis BCG Attenuates Surface Expression of Mature Class II Molecules through IL-10-Dependent Inhibition of Cathepsin S.

K. Sendide, A.-E. Deghmane, D. Pechkovsky, Y. Av-Gay, A. Talal, and Z. Hmama (2005)
J. Immunol. 175, 5324-5332
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Characterizing the Mechanisms of Progression in Multiple Sclerosis: Evidence and New Hypotheses for Future Directions.

E. M. Frohman, M. Filippi, O. Stuve, S. G. Waxman, J. Corboy, J. T. Phillips, C. Lucchinetti, J. Wilken, N. Karandikar, B. Hemmer, et al. (2005)
Arch Neurol 62, 1345-1356
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A Defective Viral Superantigen-Presenting Phenotype in HLA-DR Transfectants Is Corrected by CIITA.

G. A. Azar, R.-P. Sekaly, and J. Thibodeau (2005)
J. Immunol. 174, 7548-7557
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Collagen {alpha}1(I) Gene (COL1A1) Is Repressed by RFX Family.

P. Sengupta, Y. Xu, L. Wang, R. Widom, and B. D. Smith (2005)
J. Biol. Chem. 280, 21004-21014
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Mycobacteria Inhibition of IFN-{gamma} Induced HLA-DR Gene Expression by Up-Regulating Histone Deacetylation at the Promoter Region in Human THP-1 Monocytic Cells.

Y. Wang, H. M. Curry, B. S. Zwilling, and W. P. Lafuse (2005)
J. Immunol. 174, 5687-5694
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Long Distance Control of MHC Class II Expression by Multiple Distal Enhancers Regulated by Regulatory Factor X Complex and CIITA.

M. Krawczyk, N. Peyraud, N. Rybtsova, K. Masternak, P. Bucher, E. Barras, and W. Reith (2004)
J. Immunol. 173, 6200-6210
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CHARACTERIZATION OF THE EARLY CELLULAR IMMUNE RESPONSE TO LEISHMANIA MAJOR USING PERIPHERAL BLOOD MONONUCLEAR CELLS FROM LEISHMANIA-NAIVE HUMANS.

K. A. ROGERS and R. G. TITUS (2004)
Am J Trop Med Hyg 71, 568-576
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Altered Th1 Cell Differentiation Programming by CIITA Deficiency.

D. R. Patel, M. H. Kaplan, and C.-H. Chang (2004)
J. Immunol. 173, 5501-5508
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Major Histocompatibility Class II Transactivator (CIITA) Mediates Repression of Collagen (COL1A2) Transcription by Interferon {gamma} (IFN-{gamma}).

Y. Xu, L. Wang, G. Buttice, P. K. Sengupta, and B. D. Smith (2004)
J. Biol. Chem. 279, 41319-41332
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T cell expression of CIITA represses Th1 immunity.

W. S. Park, Y. Bae, D. H. Chung, Y.-L. Choi, B. K. Kim, Y. C. Sung, E. Y. Choi, S. H. Park, and K. C. Jung (2004)
Int. Immunol. 16, 1355-1364
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Dissection of the HLA-DR4 Peptide Repertoire in Endocrine Epithelial Cells: Strong Influence of Invariant Chain and HLA-DM Expression on the Nature of Ligands.

A. Muntasell, M. Carrascal, I. Alvarez, L. Serradell, P. van Veelen, F. A. W. Verreck, F. Koning, J. Abian, and D. Jaraquemada (2004)
J. Immunol. 173, 1085-1093
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Oct-1 Maintains an Intermediate, Stable State of HLA-DRA Promoter Repression in Rb-defective Cells: AN Oct-1-CONTAINING REPRESSOSOME THAT PREVENTS NF-Y BINDING TO THE HLA-DRA PROMOTER.

A. R. Osborne, H. Zhang, G. Fejer, K. M. Palubin, M. I. Niesen, and G. Blanck (2004)
J. Biol. Chem. 279, 28911-28919
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Mycobacterium bovis BCG Urease Attenuates Major Histocompatibility Complex Class II Trafficking to the Macrophage Cell Surface.

K. Sendide, A.-E. Deghmane, J.-M. Reyrat, A. Talal, and Z. Hmama (2004)
Infect. Immun. 72, 4200-4209
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Serine Residues 286, 288, and 293 within the CIITA: A Mechanism for Down-Regulating CIITA Activity through Phosphorylation.

S. F. Greer, J. A. Harton, M. W. Linhoff, C. A. Janczak, J. P.-Y. Ting, and D. E. Cressman (2004)
J. Immunol. 173, 376-383
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Statins as Immunomodulatory Agents.

F. Mach (2004)
Circulation 109, II-15-II-17
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Mycobacterium tuberculosis Inhibits Macrophage Responses to IFN-{gamma} through Myeloid Differentiation Factor 88-Dependent and -Independent Mechanisms.

S. M. Fortune, A. Solache, A. Jaeger, P. J. Hill, J. T. Belisle, B. R. Bloom, E. J. Rubin, and J. D. Ernst (2004)
J. Immunol. 172, 6272-6280
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Importance of class II transactivator leucine-rich repeats for dominant-negative function and nucleo-cytoplasmic transport.

M. M. Camacho-Carvajal, S. Klingler, F. Schnappauf, S. B. Hake, and V. Steimle (2004)
Int. Immunol. 16, 65-75
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Interferon {gamma} Repression of Collagen (COL1A2) Transcription Is Mediated by the RFX5 Complex.

Y. Xu, L. Wang, G. Buttice, P. K. Sengupta, and B. D. Smith (2003)
J. Biol. Chem. 278, 49134-49144
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Steroid Receptor Coactivator 1 Links the Steroid and Interferon {gamma} Response Pathways.

E. Tzortzakaki, C. Spilianakis, E. Zika, A. Kretsovali, and J. Papamatheakis (2003)
Mol. Endocrinol. 17, 2509-2518
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Differential Usage of Class II Transactivator Promoters PI and PIV during Inflammation and Injury in Kidney.

O. Takeuchi, T. N. Sims, Y. Takei, V. Ramassar, K. S. Famulski, and P. F. Halloran (2003)
J. Am. Soc. Nephrol. 14, 2823-2832
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IFN-{gamma}-Induced MHC Class II Expression: Transactivation of Class II Transactivator Promoter IV by IFN Regulatory Factor-1 is Regulated by Protein Kinase C-{alpha}.

M. Giroux, M. Schmidt, and A. Descoteaux (2003)
J. Immunol. 171, 4187-4194
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Phosphorylation of class II transactivator regulates its interaction ability and transactivation function.

T. J. Sisk, K. Nickerson, R. P. S. Kwok, and C.-H. Chang (2003)
Int. Immunol. 15, 1195-1205
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CpG DNA Induces a Class II Transactivator-Independent Increase in Class II MHC by Stabilizing Class II MHC mRNA in B Lymphocytes.

J. Kuchtey, M. Pennini, R. K. Pai, and C. V. Harding (2003)
J. Immunol. 171, 2320-2325
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Class II Transactivator (CIITA) Promoter Methylation Does Not Correlate with Silencing of CIITA Transcription in Trophoblasts.

R. Holtz, J. C. Choi, M. G. Petroff, J. F. Piskurich, and S. P. Murphy (2003)
Biol Reprod 69, 915-924
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Human cytomegalovirus protein pp65 mediates accumulation of HLA-DR in lysosomes and destruction of the HLA-DR {alpha}-chain.

J. Odeberg, B. Plachter, L. Branden, and C. Soderberg-Naucler (2003)
Blood 101, 4870-4877
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Normal Human Kidney HLA-DR-Expressing Renal Microvascular Endothelial Cells: Characterization, Isolation, and Regulation of MHC Class II Expression.

K. A. Muczynski, D. M. Ekle, D. M. Coder, and S. K. Anderson (2003)
J. Am. Soc. Nephrol. 14, 1336-1348
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Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells.

J.-M. Waldburger, S. Rossi, G. A. Hollander, H.-R. Rodewald, W. Reith, and H. Acha-Orbea (2003)
Blood 101, 3550-3559
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ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro.

H. Tsujimura, T. Tamura, C. Gongora, J. Aliberti, C. Reis e Sousa, A. Sher, and K. Ozato (2003)
Blood 101, 961-969
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The GTP-Binding Domain of Class II Transactivator Regulates Its Nuclear Export.

A. Raval, J. D. Weissman, T. K. Howcroft, and D. S. Singer (2003)
J. Immunol. 170, 922-930
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Role for RFX Transcription Factors in Non-neuronal Cell-specific Inactivation of the Microtubule-associated Protein MAP1A Promoter.

A. Nakayama, H. Murakami, N. Maeyama, N. Yamashiro, A. Sakakibara, N. Mori, and M. Takahashi (2003)
J. Biol. Chem. 278, 233-240
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Transcriptional Regulation of the MHC Class II Trans-Activator (CIITA) Promoter III: Identification of a Novel Regulatory Region in the 5'-Untranslated Region and an Important Role for cAMP-Responsive Element Binding Protein 1 and Activating Transcription Factor-1 in CIITA-Promoter III Transcriptional Activation in B Lymphocytes.

N. van der Stoep, E. Quinten, and P. J. van den Elsen (2002)
J. Immunol. 169, 5061-5071
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Modulation of Gene Expression by the MHC Class II Transactivator.

U. M. Nagarajan, A. Bushey, and J. M. Boss (2002)
J. Immunol. 169, 5078-5088
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DNA Alkylating Agents Alleviate Silencing of Class II Transactivator Gene Expression in L1210 Lymphoma Cells.

S. P. Murphy, R. Holtz, N. Lewandowski, T. B. Tomasi, and H. Fuji (2002)
J. Immunol. 169, 3085-3093
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A Novel Transactivating Factor That Regulates Interferon-gamma -dependent Gene Expression.

J. Hu, Q. Meng, S. K. Roy, A. Raha, J. Hu, J. Zhang, K. Hashimoto, and D. V. Kalvakolanu (2002)
J. Biol. Chem. 277, 30253-30263
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Isoforms of the class II transactivator protein.

G. Barbieri, V. Deffrennes, T. Prod'homme, J. Vedrenne, F. Baton, C. Cortes, A. Fischer, M.-R. Bono, B. Lisowska-Grospierre, D. Charron, et al. (2002)
Int. Immunol. 14, 839-848
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Regulation of Class II MHC Expression in APCs: Roles of Types I, III, and IV Class II Transactivator.

R. K. Pai, D. Askew, W. H. Boom, and C. V. Harding (2002)
J. Immunol. 169, 1326-1333
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Inhibition of Major Histocompatibility Complex Class II Gene Transcription by Nitric Oxide and Antioxidants.

M. Grimm, M. Spiecker, R. De Caterina, W. S. Shin, and J. K. Liao (2002)
J. Biol. Chem. 277, 26460-26467
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The RFX Family Interacts at the Collagen (COL1A2) Start Site and Represses Transcription.

P. K. Sengupta, J. Fargo, and B. D. Smith (2002)
J. Biol. Chem. 277, 24926-24937
 |  Abstract »  |  Full Text »  |  PDF »

Kinetics of a Gamma Interferon Response: Expression and Assembly of CIITA Promoter IV and Inhibition by Methylation.

A. C. Morris, G. W. Beresford, M. R. Mooney, and J. M. Boss (2002)
Mol. Cell. Biol. 22, 4781-4791
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Complicated Mechanisms of Class II Transactivator Transcription Deficiency in Small Cell Lung Cancer and Neuroblastoma.

T. Yazawa, T. Ito, H. Kamma, T. Suzuki, K. Okudela, H. Hayashi, H. Horiguchi, T. Ogata, H. Mitsui, M. Ikeda, et al. (2002)
Am. J. Pathol. 161, 291-300
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MEKK1 plays a critical role in activating the transcription factor C/EBP-beta -dependent gene expression in response to IFN-gamma.

S. K. Roy, J. Hu, Q. Meng, Y. Xia, P. S. Shapiro, S. P. M. Reddy, L. C. Platanias, D. J. Lindner, P. F. Johnson, C. Pritchard, et al. (2002)
PNAS 99, 7945-7950
 |  Abstract »  |  Full Text »  |  PDF »

Control of Expression of Major Histocompatibility Complex Genes in Horse Trophoblast.

S.J. Bacon, S.A. Ellis, and D.F. Antczak (2002)
Biol Reprod 66, 1612-1620
 |  Abstract »  |  Full Text »  |  PDF »

MHC class II-deficient tumor cell lines with a defective expression of the class II transactivator.

R. Naves, A. M. Lennon, G. Barbieri, L. Reyes, G. Puga, L. Salas, V. Deffrennes, M. Rosemblatt, M. Fellous, D. Charron, et al. (2002)
Int. Immunol. 14, 481-491
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Aberrant Expression of Fas Ligand in Mice Deficient for the MHC Class II Transactivator.

T. S. Gourley, D. R. Patel, K. Nickerson, S.-C. Hong, and C.-H. Chang (2002)
J. Immunol. 168, 4414-4419
 |  Abstract »  |  Full Text »  |  PDF »

De Novo Central Nervous System Processing of Myelin Antigen Is Required for the Initiation of Experimental Autoimmune Encephalomyelitis.

S. M. Tompkins, J. Padilla, M. C. Dal Canto, J. P.-Y. Ting, L. Van Kaer, and S. D. Miller (2002)
J. Immunol. 168, 4173-4183
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{alpha} as an immunotherapeutic protein.

D. L. Brassard, M. J. Grace, and R. W. Bordens (2002)
J. Leukoc. Biol. 71, 565-581
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Nuclear Gamma Interferon Gene Expression by Interleukin 12 (IL-12) and IL-2 Represents a Novel Form of Posttranscriptional Control.

D. L. Hodge, A. Martinez, J. G. Julias, L. S. Taylor, and H. A. Young (2002)
Mol. Cell. Biol. 22, 1742-1753
 |  Abstract »  |  Full Text »  |  PDF »

PPAR{gamma} but not PPAR{alpha} Ligands Are Potent Repressors of Major Histocompatibility Complex Class II Induction in Atheroma-Associated Cells.

B. R. Kwak, S. Myit, F. Mulhaupt, N. Veillard, N. Rufer, E. Roosnek, and F. Mach (2002)
Circ. Res. 90, 356-362
 |  Abstract »  |  Full Text »  |  PDF »

Class II Transactivator Is Required for Maximal Expression of HLA-DOB in B Cells.

U. M. Nagarajan, J. Lochamy, X. Chen, G. W. Beresford, R. Nilsen, P. E. Jensen, and J. M. Boss (2002)
J. Immunol. 168, 1780-1786
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Levels of Activation of Murine CD8+ Intraepithelial Lymphocytes Defined by OX40 (CD134) Expression: Effects on Cell-Mediated Cytotoxicity, IFN-{gamma}, and IL-10 Regulation.

H.-C. Wang and J. R. Klein (2001)
J. Immunol. 167, 6717-6723
 |  Abstract »  |  Full Text »  |  PDF »

A 36-Amino-Acid Region of CIITA Is an Effective Inhibitor of CBP: Novel Mechanism of Gamma Interferon-Mediated Suppression of Collagen {alpha}2(I) and Other Promoters.

X.-S. Zhu and J. P.-Y. Ting (2001)
Mol. Cell. Biol. 21, 7078-7088
 |  Abstract »  |  Full Text »  |  PDF »

Antiviral Actions of Interferons.

C. E. Samuel (2001)
Clin. Microbiol. Rev. 14, 778-809
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Nuclear Import and Export That Control the Subcellular Localization of Class II Transactivator.

D. E. Cressman, W. J. O'Connor, S. F. Greer, X.-S. Zhu, and J. P.-Y. Ting (2001)
J. Immunol. 167, 3626-3634
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Class II Expression in Monocytic Cells after HIV-1 Infection.

S. Rakoff-Nahoum, H. Chen, T. Kraus, I. George, E. Oei, M. Tyorkin, E. Salik, P. Beuria, and K. Sperber (2001)
J. Immunol. 167, 2331-2342
 |  Abstract »  |  Full Text »  |  PDF »

Maturation of Dendritic Cells Is Accompanied by Rapid Transcriptional Silencing of Class II Transactivator (CIITA) Expression.

S. Landmann, A. Muhlethaler-Mottet, L. Bernasconi, T. Suter, J.-M. Waldburger, K. Masternak, J.-F. Arrighi, C. Hauser, A. Fontana, and W. Reith (2001)
J. Exp. Med. 194, 379-392
 |  Abstract »  |  Full Text »  |  PDF »

Self-Association of CIITA and Its Transactivation Potential.

T. J. Sisk, S. Roys, and C.-H. Chang (2001)
Mol. Cell. Biol. 21, 4919-4928
 |  Abstract »  |  Full Text »  |  PDF »

Mutation in the Class II trans-Activator Leading to a Mild Immunodeficiency.

W. Wiszniewski, M.-C. Fondaneche, F. Le Deist, M. Kanariou, F. Selz, N. Brousse, V. Steimle, G. Barbieri, C. Alcaide-Loridan, D. Charron, et al. (2001)
J. Immunol. 167, 1787-1794
 |  Abstract »  |  Full Text »  |  PDF »

Downregulation of CIITA Function by Protein Kinase A (PKA)-Mediated Phosphorylation: Mechanism of Prostaglandin E, Cyclic AMP, and PKA Inhibition of Class II Major Histocompatibility Complex Expression in Monocytic Lines.

G. Li, J. A. Harton, X. Zhu, and J. P.-Y. Ting (2001)
Mol. Cell. Biol. 21, 4626-4635
 |  Abstract »  |  Full Text »  |  PDF »

Combinations of dominant-negative class II transactivator, p300 or CDK9 proteins block the expression of MHC II genes.

S. Kanazawa and B. M. Peterlin (2001)
Int. Immunol. 13, 951-958
 |  Abstract »  |  Full Text »  |  PDF »

Constitutive Expression of MHC Class II Genes in Melanoma Cell Lines Results from the Transcription of Class II Transactivator Abnormally Initiated from Its B Cell-Specific Promoter.

V. Deffrennes, J. Vedrenne, M.-C. Stolzenberg, J. Piskurich, G. Barbieri, J. P. Ting, D. Charron, and C. Alcaide-Loridan (2001)
J. Immunol. 167, 98-106
 |  Abstract »  |  Full Text »  |  PDF »

The Smad3 Protein Is Involved in TGF-{{beta}} Inhibition of Class II Transactivator and Class II MHC Expression.

Y. Dong, L. Tang, J. J. Letterio, and E. N. Benveniste (2001)
J. Immunol. 167, 311-319
 |  Abstract »  |  Full Text »  |  PDF »

Varying Functions of Specific Major Histocompatibility Class II Transactivator Promoter III and IV Elements in Melanoma Cell Lines.

B. L. Goodwin, H. Xi, R. Tejiram, D. D. Eason, N. Ghosh, K. L. Wright, U. Nagarajan, J. M. Boss, and G. Blanck (2001)
Cell Growth Differ. 12, 327-335
 |  Abstract »  |  Full Text »  |  PDF »

Two Distinct Domains within CIITA Mediate Self-Association: Involvement of the GTP-Binding and Leucine-Rich Repeat Domains.

M. W. Linhoff, J. A. Harton, D. E. Cressman, B. K. Martin, and J. P.-Y. Ting (2001)
Mol. Cell. Biol. 21, 3001-3011
 |  Abstract »  |  Full Text »

IFN-{{gamma}} Regulation of Class II Transactivator Promoter IV in Macrophages and Microglia: Involvement of the Suppressors of Cytokine Signaling-1 Protein.

G. M. O'Keefe, V. T. Nguyen, L. Ping Tang, and E. N. Benveniste (2001)
J. Immunol. 166, 2260-2269
 |  Abstract »  |  Full Text »  |  PDF »

Human Parainfluenza Virus Type 3 Inhibits Gamma Interferon-Induced Major Histocompatibility Complex Class II Expression Directly and by Inducing Alpha/Beta Interferon.

J. Gao, B. P. De, Y. Han, S. Choudhary, R. Ransohoff, and A. K. Banerjee (2001)
J. Virol. 75, 1124-1131
 |  Abstract »  |  Full Text »

Differential Gene Expression Profiles of Scirrhous Gastric Cancer Cells with High Metastatic Potential to Peritoneum or Lymph Nodes.

Y. Hippo, M. Yashiro, M. Ishii, H. Taniguchi, S. Tsutsumi, K. Hirakawa, T. Kodama, and H. Aburatani (2001)
Cancer Res. 61, 889-895
 |  Abstract »  |  Full Text »

New Evidence for Beneficial Effects of Statins Unrelated to Lipid Lowering.

W. Palinsk (2001)
Arterioscler. Thromb. Vasc. Biol. 21, 3-5
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The Expression of MHC Class II Genes in Macrophages Is Cell Cycle Dependent.

J. Xaus, M. Comalada, M. Barrachina, C. Herrero, E. Gonalons, C. Soler, J. Lloberas, and A. Celada (2000)
J. Immunol. 165, 6364-6371
 |  Abstract »  |  Full Text »  |  PDF »

Acetylation by PCAF Enhances CIITA Nuclear Accumulation and Transactivation of Major Histocompatibility Complex Class II Genes.

C. Spilianakis, J. Papamatheakis, and A. Kretsovali (2000)
Mol. Cell. Biol. 20, 8489-8498
 |  Abstract »  |  Full Text »

Cloning of an interferon regulatory factor 2 isoform with different regulatory ability.

S. A. K. Merediz, M. Schmidt, G. J. Hoppe, J. Alfken, D. Meraro, B.-Z. Levi, A. Neubauer, and B. Wittig (2000)
Nucleic Acids Res. 28, 4219-4224
 |  Abstract »  |  Full Text »  |  PDF »

CIITA Leucine-Rich Repeats Control Nuclear Localization, In Vivo Recruitment to the Major Histocompatibility Complex (MHC) Class II Enhanceosome, and MHC Class II Gene Transactivation.

S. B. Hake, K. Masternak, C. Kammerbauer, C. Janzen, W. Reith, and V. Steimle (2000)
Mol. Cell. Biol. 20, 7716-7725
 |  Abstract »  |  Full Text »

Class II Transactivator: Mastering the Art of Major Histocompatibility Complex Expression.

J. A. Harton and J. P.-Y. Ting (2000)
Mol. Cell. Biol. 20, 6185-6194
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Associations and Interactions between Bare Lymphocyte Syndrome Factors.

A. M. DeSandro, U. M. Nagarajan, and J. M. Boss (2000)
Mol. Cell. Biol. 20, 6587-6599
 |  Abstract »  |  Full Text »

Transcriptional Scaffold: CIITA Interacts with NF-Y, RFX, and CREB To Cause Stereospecific Regulation of the Class II Major Histocompatibility Complex Promoter.

X.-S. Zhu, M. W. Linhoff, G. Li, K.-C. Chin, S. N. Maity, and J. P.-Y. Ting (2000)
Mol. Cell. Biol. 20, 6051-6061
 |  Abstract »  |  Full Text »

Identification of Class II Transcriptional Activator-Induced Genes by Representational Difference Analysis: Discoordinate Regulation of the DN{alpha}/DO{beta} Heterodimer.

D. J. Taxman, D. E. Cressman, and J. P.-Y. Ting (2000)
J. Immunol. 165, 1410-1416
 |  Abstract »  |  Full Text »  |  PDF »

An Epithelial Cell Line That Can Stimulate Alloproliferation of Resting CD4+ T Cells, But Not After IFN-{gamma} Stimulation.

C. Lawson, A. M. McCormack, D. Moyes, S. Yun, J. W. Fabre, M. Yacoub, and M. L. Rose (2000)
J. Immunol. 165, 734-742
 |  Abstract »  |  Full Text »  |  PDF »

Synergistic induction of HLA class I expression by RelA and CIITA.

J. Girdlestone (2000)
Blood 95, 3804-3808
 |  Abstract »  |  Full Text »  |  PDF »

A Functionally Essential Domain of RFX5 Mediates Activation of Major Histocompatibility Complex Class II Promoters by Promoting Cooperative Binding between RFX and NF-Y.

J. Villard, M. Peretti, K. Masternak, E. Barras, G. Caretti, R. Mantovani, and W. Reith (2000)
Mol. Cell. Biol. 20, 3364-3376
 |  Abstract »  |  Full Text »

Molecular Anatomy of BCL6 Translocations Revealed by Long-Distance Polymerase Chain Reaction-based Assays.

H. Akasaka, T. Akasaka, M. Kurata, C. Ueda, A. Shimizu, T. Uchiyama, and H. Ohno (2000)
Cancer Res. 60, 2335-2341
 |  Abstract »  |  Full Text »

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