Science 1 July 1994: Vol. 265. no. 5168, pp. 103 - 106 DOI: 10.1126/science.8016642

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Articles

Extra-Germ Cell Expression of Mouse Nuclear Receptor Subfamily 6, Group A, Member 1 (NR6A1).

Z.-J. Lan, X. Xu, A. C.-K. Chung, and A. J. Cooney (2009)
Biol Reprod 80, 905-912
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Knock-In Mouse Lines Expressing either Mitochondrial or Microsomal CYP1A1: Differing Responses to Dietary Benzo[a]pyrene as Proof of Principle.

H. Dong, T. P. Dalton, M. L. Miller, Y. Chen, S. Uno, Z. Shi, H. G. Shertzer, S. Bansal, N. G. Avadhani, and D. W. Nebert (2009)
Mol. Pharmacol. 75, 555-567
 |  Abstract »  |  Full Text »  |  PDF »

Multiplex RT-PCR Expression Analysis of Developmentally Important Genes in Individual Mouse Preimplantation Embryos and Blastomeres.

A. May, R. Kirchner, H. Muller, P. Hartmann, N. El Hajj, A. Tresch, U. Zechner, W. Mann, and T. Haaf (2009)
Biol Reprod 80, 194-202
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Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of {beta}-catenin in mice.

T. Grigoryan, P. Wend, A. Klaus, and W. Birchmeier (2008)
Genes & Dev. 22, 2308-2341
 |  Abstract »  |  Full Text »  |  PDF »

Optimized adeno-associated virus 8 produces hepatocyte-specific Cre-mediated recombination without toxicity or affecting liver regeneration.

K. J. Ho, C. E. Bass, A. H. K. Kroemer, C. Ma, E. Terwilliger, and S. J. Karp (2008)
Am J Physiol Gastrointest Liver Physiol 295, G412-G419
 |  Abstract »  |  Full Text »  |  PDF »

Loss of Glucocorticoid Receptor Function in the Pituitary Results in Early Postnatal Lethality.

G. Erdmann, G. Schutz, and S. Berger (2008)
Endocrinology 149, 3446-3451
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Peripheral T Cells Are the Therapeutic Targets of Glucocorticoids in Experimental Autoimmune Encephalomyelitis.

S. Wust, J. van den Brandt, D. Tischner, A. Kleiman, J. P. Tuckermann, R. Gold, F. Luhder, and H. M. Reichardt (2008)
J. Immunol. 180, 8434-8443
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Txnip balances metabolic and growth signaling via PTEN disulfide reduction.

S. T. Y. Hui, A. M. Andres, A. K. Miller, N. J. Spann, D. W. Potter, N. M. Post, A. Z. Chen, S. Sachithanantham, D. Y. Jung, J. K. Kim, et al. (2008)
PNAS 105, 3921-3926
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Early Neuronal and Glial Fate Restriction of Embryonic Neural Stem Cells.

D. Delaunay, K. Heydon, A. Cumano, M. H. Schwab, J.-L. Thomas, U. Suter, K.-A. Nave, B. Zalc, and N. Spassky (2008)
J. Neurosci. 28, 2551-2562
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Cytokine knockouts in reproduction: the use of gene ablation to dissect roles of cytokines in reproductive biology.

W. V. Ingman and R. L. Jones (2008)
Hum. Reprod. Update 14, 179-192
 |  Abstract »  |  Full Text »  |  PDF »

Use of a Cryptic Splice Site for the Expression of Huntingtin Interacting Protein 1 in Select Normal and Neoplastic Tissues.

C. W. Graves, S. T. Philips, S. V. Bradley, K. I. Oravecz-Wilson, L. Li, A. Gauvin, and T. S. Ross (2008)
Cancer Res. 68, 1064-1073
 |  Abstract »  |  Full Text »  |  PDF »

Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast cell lines to methylmethane sulfonate treatment: implication of base excision repair pathways.

C. N. Kundu, R. Balusu, A. S. Jaiswal, and S. Narayan (2007)
Carcinogenesis 28, 2089-2095
 |  Abstract »  |  Full Text »  |  PDF »

Targeting Cre Recombinase to Specific Neuron Populations with Bacterial Artificial Chromosome Constructs.

S. Gong, M. Doughty, C. R. Harbaugh, A. Cummins, M. E. Hatten, N. Heintz, and C. R. Gerfen (2007)
J. Neurosci. 27, 9817-9823
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A randomized library approach to identifying functional lox site domains for the Cre recombinase.

J. Sheren, S. J. Langer, and L. A. Leinwand (2007)
Nucleic Acids Res.
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Repressor Erf Determines Extraembryonic Ectoderm Differentiation.

C. Papadaki, M. Alexiou, G. Cecena, M. Verykokakis, A. Bilitou, J. C. Cross, R. G. Oshima, and G. Mavrothalassitis (2007)
Mol. Cell. Biol. 27, 5201-5213
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Genetically manipulated mice: a powerful tool with unsuspected caveats.

K. I. Matthaei (2007)
J. Physiol. 582, 481-488
 |  Abstract »  |  Full Text »  |  PDF »

Conditional Mutagenesis of the Genome Using Site-Specific DNA Recombination.

K. Ohtsubo and J. D. Marth (2007)
CSH Protocols 2007, pdb.top12
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Conditional Inactivation of the E-Cadherin Gene in Thyroid Follicular Cells Affects Gland Development but Does Not Impair Junction Formation.

G. Cali, M. Zannini, P. Rubini, C. Tacchetti, B. D'Andrea, A. Affuso, T. Wintermantel, O. Boussadia, D. Terracciano, D. Silberschmidt, et al. (2007)
Endocrinology 148, 2737-2746
 |  Abstract »  |  Full Text »  |  PDF »

Mammary carcinogenesis in transgenic mice expressing a dominant-negative mutant of DNA polymerase {beta} in their mammary glands.

L. Wang, N. Bhattacharyya, T. Rabi, L. Wang, and S. Banerjee (2007)
Carcinogenesis 28, 1356-1363
 |  Abstract »  |  Full Text »  |  PDF »

Manipulating Mitotic Recombination in the Zebrafish Embryo Through RecQ Helicases.

J. Xie, S. L. Bessling, T. K. Cooper, H. C. Dietz, A. S. McCallion, and S. Fisher (2007)
Genetics 176, 1339-1342
 |  Abstract »  |  Full Text »  |  PDF »

DMP1-targeted Cre Expression in Odontoblasts and Osteocytes.

Y. Lu, Y. Xie, S. Zhang, V. Dusevich, L.F. Bonewald, and J.Q. Feng (2007)
Journal of Dental Research 86, 320-325
 |  Abstract »  |  Full Text »  |  PDF »

Conditional Knockout Mice Reveal an Essential Role of Protein Phosphatase 4 in Thymocyte Development and Pre-T-Cell Receptor Signaling.

J.-W. Shui, M. C.-T. Hu, and T.-H. Tan (2007)
Mol. Cell. Biol. 27, 79-91
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Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton.

T. A. Kalfa, S. Pushkaran, N. Mohandas, J. H. Hartwig, V. M. Fowler, J. F. Johnson, C. H. Joiner, D. A. Williams, and Y. Zheng (2006)
Blood 108, 3637-3645
 |  Abstract »  |  Full Text »  |  PDF »

Haploinsufficiency in DNA Polymerase {beta} Increases Cancer Risk with Age and Alters Mortality Rate..

D. C. Cabelof, Y. Ikeno, A. Nyska, R. A. Busuttil, N. Anyangwe, J. Vijg, L. H. Matherly, J. D. Tucker, S. H. Wilson, A. Richardson, et al. (2006)
Cancer Res. 66, 7460-7465
 |  Abstract »  |  Full Text »  |  PDF »

Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci.

M. A. Inlay, T. Lin, H. H. Gao, and Y. Xu (2006)
J. Exp. Med. 203, 1721-1732
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alx, a Zebrafish Homolog of Chx10, Marks Ipsilateral Descending Excitatory Interneurons That Participate in the Regulation of Spinal Locomotor Circuits.

Y. Kimura, Y. Okamura, and S.-i. Higashijima (2006)
J. Neurosci. 26, 5684-5697
 |  Abstract »  |  Full Text »  |  PDF »

Early Embryonic Lethality Due to Targeted Inactivation of DNA Ligase III.

N. Puebla-Osorio, D. B. Lacey, F. W. Alt, and C. Zhu (2006)
Mol. Cell. Biol. 26, 3935-3941
 |  Abstract »  |  Full Text »  |  PDF »

Requirement of Rac1 in the development of cardiac hypertrophy.

M. Satoh, H. Ogita, K. Takeshita, Y. Mukai, D. J. Kwiatkowski, and J. K. Liao (2006)
PNAS 103, 7432-7437
 |  Abstract »  |  Full Text »  |  PDF »

Base excision repair fidelity in normal and cancer cells.

K. K.L. Chan, Q.-M. Zhang, and G. L. Dianov (2006)
Mutagenesis 21, 173-178
 |  Abstract »  |  Full Text »  |  PDF »

Generation and characterization of telomere length maintenance in tankyrase 2-deficient mice..

Y. J. Chiang, M.-L. Nguyen, S. Gurunathan, P. Kaminker, L. Tessarollo, J. Campisi, and R. J. Hodes (2006)
Mol. Cell. Biol. 26, 2037-2043
 |  Abstract »  |  Full Text »  |  PDF »

Inducible model for {beta}-six-mediated site-specific recombination in mammalian cells.

P. Servert, J. Garcia-Castro, V. Diaz, D. Lucas, M. A. Gonzalez, C. Martinez-A, and A. Bernad (2006)
Nucleic Acids Res. 34, e1
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Decreased mutant frequency in embryonic brain of DNA polymerase {beta} null mice.

N. Niimi, N. Sugo, Y. Aratani, Y. Gondo, M. Katsuki, and H. Koyama (2006)
Mutagenesis 21, 55-59
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From the Cover: Epicardial retinoid X receptor {alpha} is required for myocardial growth and coronary artery formation.

E. Merki, M. Zamora, A. Raya, Y. Kawakami, J. Wang, X. Zhang, J. Burch, S. W. Kubalak, P. Kaliman, J. C. I. Belmonte, et al. (2005)
PNAS 102, 18455-18460
 |  Abstract »  |  Full Text »  |  PDF »

Targeted Deletion of Integrin-Linked Kinase Reveals a Role in T-Cell Chemotaxis and Survival.

E. Liu, S. Sinha, C. Williams, M. Cyrille, E. Heller, S. B. Snapper, K. Georgopoulos, R. St-Arnaud, T. Force, S. Dedhar, et al. (2005)
Mol. Cell. Biol. 25, 11145-11155
 |  Abstract »  |  Full Text »  |  PDF »

Apoptosis of Oligodendrocytes via Fas and TNF-R1 Is a Key Event in the Induction of Experimental Autoimmune Encephalomyelitis.

N. Hovelmeyer, Z. Hao, K. Kranidioti, G. Kassiotis, T. Buch, F. Frommer, L. von Hoch, D. Kramer, L. Minichiello, G. Kollias, et al. (2005)
J. Immunol. 175, 5875-5884
 |  Abstract »  |  Full Text »  |  PDF »

Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctions.

V Valiunas, Y. Y Polosina, H Miller, I. A Potapova, L Valiuniene, S Doronin, R. T Mathias, R. B Robinson, M. R Rosen, I. S Cohen, et al. (2005)
J. Physiol. 568, 459-468
 |  Abstract »  |  Full Text »  |  PDF »

The Hydrophobic Hinge Region of Rat DNA Polymerase {beta} Is Critical for Substrate Binding Pocket Geometry.

D. Starcevic, S. Dalal, J. Jaeger, and J. B. Sweasy (2005)
J. Biol. Chem. 280, 28388-28393
 |  Abstract »  |  Full Text »  |  PDF »

Frequent Coinfection of Cells Explains Functional In Vivo Complementation between Cytomegalovirus Variants in the Multiply Infected Host.

L. Cicin-Sain, J. Podlech, M. Messerle, M. J. Reddehase, and U. H. Koszinowski (2005)
J. Virol. 79, 9492-9502
 |  Abstract »  |  Full Text »  |  PDF »

Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia.

D. M. Langenau, H. Feng, S. Berghmans, J. P. Kanki, J. L. Kutok, and A. T. Look (2005)
PNAS 102, 6068-6073
 |  Abstract »  |  Full Text »  |  PDF »

Contribution of DNA polymerase {eta} to immunoglobulin gene hypermutation in the mouse.

F. Delbos, A. De Smet, A. Faili, S. Aoufouchi, J.-C. Weill, and C.-A. Reynaud (2005)
J. Exp. Med. 201, 1191-1196
 |  Abstract »  |  Full Text »  |  PDF »

The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells.

E. S. Ng, L. Azzola, K. Sourris, L. Robb, E. G. Stanley, and A. G. Elefanty (2005)
Development 132, 873-884
 |  Abstract »  |  Full Text »  |  PDF »

Gene trap and gene inversion methods for conditional gene inactivation in the mouse.

H.-B. Xin, K.-Y. Deng, B. Shui, S. Qu, Q. Sun, J. Lee, K. S. Greene, J. Wilson, Y. Yu, M. Feldman, et al. (2005)
Nucleic Acids Res. 33, e14
 |  Abstract »  |  Full Text »  |  PDF »

The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase {beta} defective mammalian cells.

B. Pascucci, M. T. Russo, M. Crescenzi, M. Bignami, and E. Dogliotti (2005)
Nucleic Acids Res. 33, 280-288
 |  Abstract »  |  Full Text »  |  PDF »

Technical Assessment of the First 20 Years of Research Using Mouse Embryonic Stem Cell Lines.

G. J. Downing and J. F. Battey Jr. (2004)
Stem Cells 22, 1168-1180
 |  Abstract »  |  Full Text »  |  PDF »

p53 Deficiency Rescues Neuronal Apoptosis but Not Differentiation in DNA Polymerase {beta}-Deficient Mice.

N. Sugo, N. Niimi, Y. Aratani, K. Takiguchi-Hayashi, and H. Koyama (2004)
Mol. Cell. Biol. 24, 9470-9477
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Nuclear Protein, MGC5306 Interacts with DNA Polymerase {beta} and Has a Potential Role in Cellular Phenotype.

L. Wang, N. Bhattacharyya, D. M. Chelsea, P. F. Escobar, and S. Banerjee (2004)
Cancer Res. 64, 7673-7677
 |  Abstract »  |  Full Text »  |  PDF »

Differential Oocyte-Specific Expression of Cre Recombinase Activity in GDF-9-iCre, Zp3cre, and Msx2Cre Transgenic Mice.

Z.-J. Lan, X. Xu, and A. J. Cooney (2004)
Biol Reprod 71, 1469-1474
 |  Abstract »  |  Full Text »  |  PDF »

Requirement of c-myb in T cell development and in mature T cell function.

Y. K. Lieu, A. Kumar, A. G. Pajerowski, T. J. Rogers, and E. P. Reddy (2004)
PNAS 101, 14853-14858
 |  Abstract »  |  Full Text »  |  PDF »

The Loss of PTEN Allows TCR {alpha}{beta} Lineage Thymocytes to Bypass IL-7 and Pre-TCR-mediated Signaling.

T. J. Hagenbeek, M. Naspetti, F. Malergue, F. Garcon, J. A. Nunes, K. B.J.M. Cleutjens, J. Trapman, P. Krimpenfort, and H. Spits (2004)
J. Exp. Med. 200, 883-894
 |  Abstract »  |  Full Text »  |  PDF »

Lung-targeted VEGF inactivation leads to an emphysema phenotype in mice.

K. Tang, H. B. Rossiter, P. D. Wagner, and E. C. Breen (2004)
J Appl Physiol 97, 1559-1566
 |  Abstract »  |  Full Text »  |  PDF »

Imbalanced Base Excision Repair in Response to Folate Deficiency Is Accelerated by Polymerase {beta} Haploinsufficiency.

D. C. Cabelof, J. J. Raffoul, J. Nakamura, D. Kapoor, H. Abdalla, and A. R. Heydari (2004)
J. Biol. Chem. 279, 36504-36513
 |  Abstract »  |  Full Text »  |  PDF »

Deletion of the alternatively spliced fibronectin EIIIA domain in mice reduces atherosclerosis.

M. H. Tan, Z. Sun, S. L. Opitz, T. E. Schmidt, J. H. Peters, and E. L. George (2004)
Blood 104, 11-18
 |  Abstract »  |  Full Text »  |  PDF »

Capillary regression in vascular endothelial growth factor-deficient skeletal muscle.

K. Tang, E. C. Breen, H.-P. Gerber, N. M. A. Ferrara, and P. D. Wagner (2004)
Physiol Genomics 18, 63-69
 |  Abstract »  |  Full Text »  |  PDF »

Cardiac-specific Knock-out of Lipoprotein Lipase Alters Plasma Lipoprotein Triglyceride Metabolism and Cardiac Gene Expression.

A. Augustus, H. Yagyu, G. Haemmerle, A. Bensadoun, R. K. Vikramadithyan, S.-Y. Park, J. K. Kim, R. Zechner, and I. J. Goldberg (2004)
J. Biol. Chem. 279, 25050-25057
 |  Abstract »  |  Full Text »  |  PDF »

Control of siRNA expression using the Cre-loxP recombination system.

V. Kasim, M. Miyagishi, and K. Taira (2004)
Nucleic Acids Res. 32, e66
 |  Abstract »  |  Full Text »  |  PDF »

Melanocytes and Pigmentation Are Affected in Dopachrome Tautomerase Knockout Mice.

L. Guyonneau, F. Murisier, A. Rossier, A. Moulin, and F. Beermann (2004)
Mol. Cell. Biol. 24, 3396-3403
 |  Abstract »  |  Full Text »  |  PDF »

Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities.

M. Bjarnegard, M. Enge, J. Norlin, S. Gustafsdottir, S. Fredriksson, A. Abramsson, M. Takemoto, E. Gustafsson, R. Fassler, and C. Betsholtz (2004)
Development 131, 1847-1857
 |  Abstract »  |  Full Text »  |  PDF »

Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair.

C.-G. Huh, V. M. Factor, A. Sanchez, K. Uchida, E. A. Conner, and S. S. Thorgeirsson (2004)
PNAS 101, 4477-4482
 |  Abstract »  |  Full Text »  |  PDF »

Conditional Ablation of the Neural Cell Adhesion Molecule Reduces Precision of Spatial Learning, Long-Term Potentiation, and Depression in the CA1 Subfield of Mouse Hippocampus.

O. Bukalo, N. Fentrop, A. Y. W. Lee, B. Salmen, J. W. S. Law, C. T. Wotjak, M. Schweizer, A. Dityatev, and M. Schachner (2004)
J. Neurosci. 24, 1565-1577
 |  Abstract »  |  Full Text »  |  PDF »

Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation.

J. A. Davies, M. Ladomery, P. Hohenstein, L. Michael, A. Shafe, L. Spraggon, and N. Hastie (2004)
Hum. Mol. Genet. 13, 235-246
 |  Abstract »  |  Full Text »  |  PDF »

Embryonic atrial function is essential for mouse embryogenesis, cardiac morphogenesis and angiogenesis.

C. Huang, F. Sheikh, M. Hollander, C. Cai, D. Becker, P.-H. Chu, S. Evans, and J. Chen (2003)
Development 130, 6111-6119
 |  Abstract »  |  Full Text »  |  PDF »

Cardiomyocyte-Specific Endothelin A Receptor Knockout Mice Have Normal Cardiac Function and an Unaltered Hypertrophic Response to Angiotensin II and Isoproterenol.

R. M. Kedzierski, P. A. Grayburn, Y. Y. Kisanuki, C. S. Williams, R. E. Hammer, J. A. Richardson, M. D. Schneider, and M. Yanagisawa (2003)
Mol. Cell. Biol. 23, 8226-8232
 |  Abstract »  |  Full Text »  |  PDF »

Decreased Anxiety, Altered Place Learning, and Increased CA1 Basal Excitatory Synaptic Transmission in Mice with Conditional Ablation of the Neural Cell Adhesion Molecule L1.

J. W. S. Law, A. Y. W. Lee, M. Sun, A. G. Nikonenko, S. K. Chung, A. Dityatev, M. Schachner, and F. Morellini (2003)
J. Neurosci. 23, 10419-10432
 |  Abstract »  |  Full Text »  |  PDF »

Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5.

W. Long, K.-U. Wagner, K. C. K. Lloyd, N. Binart, J. M. Shillingford, L. Hennighausen, and F. E. Jones (2003)
Development 130, 5257-5268
 |  Abstract »  |  Full Text »  |  PDF »

Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases.

Y. Gu, M.-D. Filippi, J. A. Cancelas, J. E. Siefring, E. P. Williams, A. C. Jasti, C. E. Harris, A. W. Lee, R. Prabhakar, S. J. Atkinson, et al. (2003)
Science 302, 445-449
 |  Abstract »  |  Full Text »  |  PDF »

Base Excision Repair Intermediates Induce p53-independent Cytotoxic and Genotoxic Responses.

R. W. Sobol, M. Kartalou, K. H. Almeida, D. F. Joyce, B. P. Engelward, J. K. Horton, R. Prasad, L. D. Samson, and S. H. Wilson (2003)
J. Biol. Chem. 278, 39951-39959
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation.

E. Ennifar, J. E. W. Meyer, F. Buchholz, A. F. Stewart, and D. Suck (2003)
Nucleic Acids Res. 31, 5449-5460
 |  Abstract »  |  Full Text »  |  PDF »

Base Excision Repair Deficiency Caused by Polymerase {beta} Haploinsufficiency: Accelerated DNA Damage and Increased Mutational Response to Carcinogens.

D. C. Cabelof, Z. Guo, J. J. Raffoul, R. W. Sobol, S. H. Wilson, A. Richardson, and A. R. Heydari (2003)
Cancer Res. 63, 5799-5807
 |  Abstract »  |  Full Text »  |  PDF »

Newer Approaches to Genetic Modeling in Mice: Tissue-Specific Protein Expression as Studied Using Angiotensin-Converting Enzyme (ACE).

H. D. Xiao, S. Fuchs, K. Frenzel, J. M. Cole, and K. E. Bernstein (2003)
Am. J. Pathol. 163, 807-817
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Focal Deletion of the Adenosine A1 Receptor in Adult Mice Using an Adeno-Associated Viral Vector.

T. E. Scammell, E. Arrigoni, M. A. Thompson, P. J. Ronan, C. B. Saper, and R. W. Greene (2003)
J. Neurosci. 23, 5762-5770
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Promoter in Maintaining Transcriptionally Active Chromatin Structure and DNA Methylation Patterns In Vivo.

S.-H. L. Kang, C. Mione Kiefer, and T. P. Yang (2003)
Mol. Cell. Biol. 23, 4150-4161
 |  Abstract »  |  Full Text »  |  PDF »

Poly(ADP-ribose) Polymerase-1 (PARP-1) Is Required in Murine Cell Lines for Base Excision Repair of Oxidative DNA Damage in the Absence of DNA Polymerase beta.

F. Le Page, V. Schreiber, C. Dherin, G. de Murcia, and S. Boiteux (2003)
J. Biol. Chem. 278, 18471-18477
 |  Abstract »  |  Full Text »  |  PDF »

IKK{beta} Is Required for Peripheral B Cell Survival and Proliferation.

Z.-W. Li, S. A. Omori, T. Labuda, M. Karin, and R. C. Rickert (2003)
J. Immunol. 170, 4630-4637
 |  Abstract »  |  Full Text »  |  PDF »

Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1{beta}.

C. Coffinier, L. Gresh, L. Fiette, F. Tronche, G. Schutz, C. Babinet, M. Pontoglio, M. Yaniv, and J. Barra (2003)
Development 129, 1829-1838
 |  Abstract »  |  Full Text »  |  PDF »

Ends-out, or replacement, gene targeting in Drosophila.

W. J. Gong and K. G. Golic (2003)
PNAS 100, 2556-2561
 |  Abstract »  |  Full Text »  |  PDF »

Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles.

P. Leneuve, S. Colnot, G. Hamard, F. Francis, M. Niwa-Kawakita, M. Giovannini, and M. Holzenberger (2003)
Nucleic Acids Res. 31, e21
 |  Abstract »  |  Full Text »  |  PDF »

Rapid generation of inducible mouse mutants.

J. Seibler, B. Zevnik, B. Kuter-Luks, S. Andreas, H. Kern, T. Hennek, A. Rode, C. Heimann, N. Faust, G. Kauselmann, et al. (2003)
Nucleic Acids Res. 31, e12
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of the Regulatory {beta} Subunit of Protein Kinase CK2 in Mice Leads to a Cell-Autonomous Defect and Early Embryonic Lethality.

T. Buchou, M. Vernet, O. Blond, H. H. Jensen, H. Pointu, B. B. Olsen, C. Cochet, O.-G. Issinger, and B. Boldyreff (2003)
Mol. Cell. Biol. 23, 908-915
 |  Abstract »  |  Full Text »

Signal-Transducing Adaptor Molecules STAM1 and STAM2 Are Required for T-Cell Development and Survival.

M. Yamada, N. Ishii, H. Asao, K. Murata, C. Kanazawa, H. Sasaki, and K. Sugamura (2002)
Mol. Cell. Biol. 22, 8648-8658
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Lineage-specific requirements of {beta}-catenin in neural crest development.

L. Hari, V. Brault, M. Kleber, H.-Y. Lee, F. Ille, R. Leimeroth, C. Paratore, U. Suter, R. Kemler, and L. Sommer (2002)
J. Cell Biol. 159, 867-880
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Tools for targeted manipulation of the mouse genome.

L. van der Weyden, D. J. Adams, and A. Bradley (2002)
Physiol Genomics 11, 133-164
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Inactivation of the F4/80 Glycoprotein in the Mouse Germ Line.

E. Schaller, A. J. Macfarlane, R. A. Rupec, S. Gordon, A. J. McKnight, and K. Pfeffer (2002)
Mol. Cell. Biol. 22, 8035-8043
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Loss of Brca2 and p53 Synergistically Promotes Genomic Instability and Deregulation of T-cell Apoptosis.

A. M. Y. Cheung, M. P. Hande, F. Jalali, M.-S. Tsao, B. Skinnider, A. Hirao, J. P. McPherson, J. Karaskova, A. Suzuki, A. Wakeham, et al. (2002)
Cancer Res. 62, 6194-6204
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The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6.

H. Akiyama, M.-C. Chaboissier, J. F. Martin, A. Schedl, and B. de Crombrugghe (2002)
Genes & Dev. 16, 2813-2828
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Mice Lacking the EDB Segment of Fibronectin Develop Normally but Exhibit Reduced Cell Growth and Fibronectin Matrix Assembly in Vitro.

T. Fukuda, N. Yoshida, Y. Kataoka, R.-i. Manabe, Y. Mizuno-Horikawa, M. Sato, K. Kuriyama, N. Yasui, and K. Sekiguchi (2002)
Cancer Res. 62, 5603-5610
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Threonine 79 Is a Hinge Residue That Governs the Fidelity of DNA Polymerase beta by Helping to Position the DNA within the Active Site.

M. Maitra, A. Gudzelak Jr., S.-X. Li, Y. Matsumoto, K. A. Eckert, J. Jager, and J. B. Sweasy (2002)
J. Biol. Chem. 277, 35550-35560
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Smooth muscle expression of Cre recombinase and eGFP in transgenic mice.

H.-B. Xin, K.-Y. Deng, M. Rishniw, G. Ji, and M. I. Kotlikoff (2002)
Physiol Genomics 10, 211-215
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Induction of DNA polymerase {beta}-dependent base excision repair in response to oxidative stress in vivo.

D. C. Cabelof, J. J. Raffoul, S. Yanamadala, Z. Guo, and A. R. Heydari (2002)
Carcinogenesis 23, 1419-1425
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Impairment of L-type Ca2+ Channel-Dependent Forms of Hippocampal Synaptic Plasticity in Mice Deficient in the Extracellular Matrix Glycoprotein Tenascin-C.

M. R. Evers, B. Salmen, O. Bukalo, A. Rollenhagen, M. R. Bosl, F. Morellini, U. Bartsch, A. Dityatev, and M. Schachner (2002)
J. Neurosci. 22, 7177-7194
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Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable.

P. Leveen, J. Larsson, M. Ehinger, C. M. Cilio, M. Sundler, L. J. Sjostrand, R. Holmdahl, and S. Karlsson (2002)
Blood 100, 560-568
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Directed evolution of the site specificity of Cre recombinase.

S. W. Santoro and P. G. Schultz (2002)
PNAS 99, 4185-4190
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Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: A tool for efficient genetic engineering of mammalian genomes.

M. Peitz, K. Pfannkuche, K. Rajewsky, and F. Edenhofer (2002)
PNAS 99, 4489-4494
 |  Abstract »  |  Full Text »  |  PDF »

Insulin-Like Growth Factor-I: Compartmentalization Within the Somatotropic Axis?.

A. A. Butler, S. Yakar, and D. LeRoith (2002)
Physiology 17, 82-85
 |  Abstract »  |  Full Text »  |  PDF »

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