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Science 10 June 1994:
Vol. 264. no. 5165, pp. 1560 - 1563
DOI: 10.1126/science.264.5165.1560

Articles

Force Detection of Nuclear Magnetic Resonance

D. Rugar 1, O. Züger 1, S. Hoen 1, C. S. Yannoni 1, H.-M. Vieth 1, and R. D. Kendrick 1

1 IBM Research Division, Almaden Research Center, 650 Harry Road, San Jose, CA 95120, USA.

Micromechanical sensing of magnetic force was used to detect nuclear magnetic resonance with exceptional sensitivity and spatial resolution. With a 900 angstrom thick silicon nitride cantilever capable of detecting subfemtonewton forces, a single shot sensitivity of 1.6 x 1013 protons was achieved for an ammonium nitrate sample mounted on the cantilever. A nearby millimeter-size iron particle produced a 600 tesla per meter magnetic field gradient, resulting in a spatial resolution of 2.6 micrometers in one dimension. These results suggest that magnetic force sensing is a viable approach for enhancing the sensitivity and spatial resolution of nuclear magnetic resonance microimaging.

Submitted on January 27, 1994
Accepted on April 25, 1994


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