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Science 3 June 1994: Vol. 264. no. 5164, pp. 1455 - 1458 DOI: 10.1126/science.8197458
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Articles
Science, Vol 264, Issue 5164, 1455-1458
Copyright © 1994 by American Association for the Advancement of Science
Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription
S Halachmi,
E Marden,
G Martin,
H MacKay,
C Abbondanza,
and
M Brown
Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA.
The estrogen receptor is a transcription factor which, when bound to estradiol, binds DNA and regulates expression of estrogen-responsive genes. A 160-kilodalton estrogen receptor-associated protein, ERAP160, was identified that exhibits estradiol-dependent binding to the receptor. Mutational analysis of the receptor shows that its ability to activate transcription parallels its ability to bind ERAP160. Antiestrogens are unable to promote ERAP160 binding and can block the estrogen-dependent interaction of the receptor and ERAP160 in a dose-dependent manner. This evidence suggests that ERAP160 may mediate estradiol-dependent transcriptional activation by the estrogen receptor. Furthermore, the ability of antiestrogens to block estrogen receptor-ERAP160 complex formation could account for their therapeutic effects in breast cancer.
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| Abstract »
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| Abstract »
| Full Text »
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| Abstract »
| Full Text »
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| Abstract »
| Full Text »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
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| Full Text »
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| Abstract »
| Full Text »
| PDF »
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19, 6509-6522
| Abstract »
| Full Text »
| PDF »
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- S. Cresci, M. L. Clabby, and D. P. Kelly (1999)
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274, 25668-25674
| Abstract »
| Full Text »
| PDF »
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19, 6323-6332
| Abstract »
| Full Text »
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- J. Zhang, X. Hu, and M. A. Lazar (1999)
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| Abstract »
| Full Text »
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| PDF »
- Retinoid X Receptor (RXR) Agonist-Induced Activation of Dominant-Negative RXR-Retinoic Acid Receptor alpha 403 Heterodimers Is Developmentally Regulated during Myeloid Differentiation.
- B. S. Johnson, R. A. S. Chandraratna, R. A. Heyman, E. A. Allegretto, L. Mueller, and S. J. Collins (1999)
Mol. Cell. Biol.
19, 3372-3382
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- Molecular Determinants of the Estrogen Receptor-Coactivator Interface.
- H. Y. Mak, S. Hoare, P. M. A. Henttu, and M. G. Parker (1999)
Mol. Cell. Biol.
19, 3895-3903
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- Melatonin blocks the activation of estrogen receptor for DNA binding.
- A. GARCÍA RATO, J. GARCÍA PEDRERO, M. A. MARTÍNEZ, B. DEL RIO, P. S. LAZO, and S. RAMOS (1999)
FASEB J
13, 857-868
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- Expression and Up-Regulation of Retinoic Acid Receptor-{beta} Is Associated with Retinoid Sensitivity and Colony Formation in Esophageal Cancer Cell Lines.
- X.-C. Xu, X. Liu, E. Tahara, S. M. Lippman, and R. Lotan (1999)
Cancer Res.
59, 2477-2483
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- Conformational Change in the Human Glucocorticoid Receptor Induced by Ligand Binding Is Altered by Mutation of Isoleucine 747 by a Threonine.
- S. Roux, B. Terouanne, B. Couette, M.-E. Rafestin-Oblin, and J.-C. Nicolas (1999)
J. Biol. Chem.
274, 10059-10065
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- Competition between Thyroid Hormone Receptor-associated Protein (TRAP) 220 and Transcriptional Intermediary Factor (TIF) 2 for Binding to Nuclear Receptors. IMPLICATIONS FOR THE RECRUITMENT OF TRAP AND p160 COACTIVATOR COMPLEXES.
- E. Treuter, L. Johansson, J. S. Thomsen, A. Warnmark, J. Leers, M. Pelto-Huikko, M. Sjoberg, A. P. H. Wright, G. Spyrou, and J.-A. Gustafsson (1999)
J. Biol. Chem.
274, 6667-6677
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- Clinical Effects of Raloxifene Hydrochloride in Women.
- W. Khovidhunkit and D. M. Shoback (1999)
Ann Intern Med
130, 431-439
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- Selective Interaction of Vitamin D Receptor with Transcriptional Coactivators by a Vitamin D Analog.
- K.-I. Takeyama, Y. Masuhiro, H. Fuse, H. Endoh, A. Murayama, S. Kitanaka, M. Suzawa, J. Yanagisawa, and S. Kato (1999)
Mol. Cell. Biol.
19, 1049-1055
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- Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ER{alpha} and ER{beta} Expressed in Chinese Hamster Ovary Cells.
- M. Razandi, A. Pedram, G. L. Greene, and E. R. Levin (1999)
Mol. Endocrinol.
13, 307-319
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- Transcriptional Regulation by a Naturally Occurring Truncated Rat Estrogen Receptor (ER), Truncated ER Product-1 (TERP-1).
- D. A. Schreihofer, E. M. Resnick, A. Y. Soh, and M. A. Shupnik (1999)
Mol. Endocrinol.
13, 320-329
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- Segregation of steroid receptor coactivator-1 from steroid receptors in mammary epithelium.
- W.-S. Shim, J. DiRenzo, J. A. DeCaprio, R. J. Santen, M. Brown, and M.-H. Jeng (1999)
PNAS
96, 208-213
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- Functional Analysis of a Novel Estrogen Receptor-{beta} Isoform.
- B. Hanstein, H. Liu, M. C. Yancisin, and M. Brown (1999)
Mol. Endocrinol.
13, 129-137
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- Calmodulin Is Essential for Estrogen Receptor Interaction with Its Motif and Activation of Responsive Promoter.
- D. K. Biswas, P. V. Reddy, M. Pickard, B. Makkad, N. Pettit, and A. B. Pardee (1998)
J. Biol. Chem.
273, 33817-33824
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- A Potent Antidiabetic Thiazolidinedione with Unique Peroxisome Proliferator-activated Receptor gamma -activating Properties.
- M. J. Reginato, S. T. Bailey, S. L. Krakow, C. Minami, S. Ishii, H. Tanaka, and M. A. Lazar (1998)
J. Biol. Chem.
273, 32679-32684
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- Bcl3, an Ikappa B Protein, as a Novel Transcription Coactivator of the Retinoid X Receptor.
- S.-Y. Na, H.-S. Choi, J. W. Kim, D. S. Na, and J. W. Lee (1998)
J. Biol. Chem.
273, 30933-30938
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- Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation.
- E. M. McInerney, D. W. Rose, S. E. Flynn, S. Westin, T.-M. Mullen, A. Krones, J. Inostroza, J. Torchia, R. T. Nolte, N. Assa-Munt, et al. (1998)
Genes & Dev.
12, 3357-3368
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- Coactivator TIF1beta Interacts with Transcription Factor C/EBPbeta and Glucocorticoid Receptor To Induce alpha 1-Acid Glycoprotein Gene Expression.
- C.-J. Chang, Y.-L. Chen, and S.-C. Lee (1998)
Mol. Cell. Biol.
18, 5880-5887
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- Distinct steady-state nuclear receptor coregulator complexes exist in vivo.
- N. J. McKenna, Z. Nawaz, S. Y. Tsai, M.-J. Tsai, and B. W. O'Malley (1998)
PNAS
95, 11697-11702
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- Identification of a Novel RING Finger Protein as a Coregulator in Steroid Receptor-Mediated Gene Transcription.
- A.-M. Moilanen, H. Poukka, U. Karvonen, M. Häkli, O. A. Jänne, and J. J. Palvimo (1998)
Mol. Cell. Biol.
18, 5128-5139
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- Tuberous Sclerosis Gene 2 Product Modulates Transcription Mediated by Steroid Hormone Receptor Family Members.
- K. W. Henry, X. Yuan, N. J. Koszewski, H. Onda, D. J. Kwiatkowski, and D. J. Noonan (1998)
J. Biol. Chem.
273, 20535-20539
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