Science 3 June 1994: Vol. 264. no. 5164, pp. 1415 - 1421 DOI: 10.1126/science.8197455

Prev | Table of Contents | Next

Articles

Stat3 promotes directional cell migration by regulating Rac1 activity via its activator {beta}PIX.

T. S. Teng, B. Lin, E. Manser, D. C. H. Ng, and X. Cao (2009)
J. Cell Sci. 122, 4150-4159
 |  Abstract »  |  Full Text »  |  PDF »

Adenosine Blocks IFN-{gamma}-Induced Phosphorylation of STAT1 on Serine 727 to Reduce Macrophage Activation.

K. E. Barnholt, R. S. Kota, H. H. Aung, and J. C. Rutledge (2009)
J. Immunol. 183, 6767-6777
 |  Abstract »  |  Full Text »  |  PDF »

Role of STAT1, NF-{kappa}B, and C/EBP{beta} in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-{gamma}.

F. B. Sow, G. R. Alvarez, R. P. Gross, A. R. Satoskar, L. S. Schlesinger, B. S. Zwilling, and W. P. Lafuse (2009)
J. Leukoc. Biol. 86, 1247-1258
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-resistant Daudi Cell Line with a Stat2 Defect Is Resistant to Apoptosis Induced by Chemotherapeutic Agents.

Z. Du, M. Fan, J.-G. Kim, D. Eckerle, L. Lothstein, L. Wei, and L. M. Pfeffer (2009)
J. Biol. Chem. 284, 27808-27815
 |  Abstract »  |  Full Text »  |  PDF »

Similarities and Differences in Antagonism of Neuron Alpha/Beta Interferon Responses by Venezuelan Equine Encephalitis and Sindbis Alphaviruses.

J. Yin, C. L. Gardner, C. W. Burke, K. D. Ryman, and W. B. Klimstra (2009)
J. Virol. 83, 10036-10047
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of JAK2 by miR-135a: prognostic impact in classic Hodgkin lymphoma.

A. Navarro, T. Diaz, A. Martinez, A. Gaya, A. Pons, B. Gel, C. Codony, G. Ferrer, C. Martinez, E. Montserrat, et al. (2009)
Blood 114, 2945-2951
 |  Abstract »  |  Full Text »  |  PDF »

Expression of renin-angiotensin system signalling compounds in maternal protein-restricted rats: effect on renal sodium excretion and blood pressure.

F. F. Mesquita, J. A. R. Gontijo, and P. A. Boer (2009)
Nephrol. Dial. Transplant.
 |  Abstract »  |  Full Text »  |  PDF »

Role of Schlafen 2 (SLFN2) in the Generation of Interferon {alpha}-induced Growth Inhibitory Responses.

E. Katsoulidis, N. Carayol, J. Woodard, I. Konieczna, B. Majchrzak-Kita, A. Jordan, A. Sassano, E. A. Eklund, E. N. Fish, and L. C. Platanias (2009)
J. Biol. Chem. 284, 25051-25064
 |  Abstract »  |  Full Text »  |  PDF »

Alpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43.

M. Sarasin-Filipowicz, X. Wang, M. Yan, F. H. T. Duong, V. Poli, D. J. Hilton, D.-E. Zhang, and M. H. Heim (2009)
Mol. Cell. Biol. 29, 4841-4851
 |  Abstract »  |  Full Text »  |  PDF »

Nipah Virus Sequesters Inactive STAT1 in the Nucleus via a P Gene-Encoded Mechanism.

M. J. Ciancanelli, V. A. Volchkova, M. L. Shaw, V. E. Volchkov, and C. F. Basler (2009)
J. Virol. 83, 7828-7841
 |  Abstract »  |  Full Text »  |  PDF »

Comparative aspects of implantation.

F. W Bazer, T. E Spencer, G. A Johnson, R. C Burghardt, and G. Wu (2009)
Reproduction 138, 195-209
 |  Abstract »  |  Full Text »  |  PDF »

Prolactin regulates ZNT2 expression through the JAK2/STAT5 signaling pathway in mammary cells.

L. Qian, V. Lopez, Y. A. Seo, and S. L. Kelleher (2009)
Am J Physiol Cell Physiol 297, C369-C377
 |  Abstract »  |  Full Text »  |  PDF »

Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses.

S. Joshi, S. Kaur, A. J. Redig, K. Goldsborough, K. David, T. Ueda, R. Watanabe-Fukunaga, D. P. Baker, E. N. Fish, R. Fukunaga, et al. (2009)
PNAS 106, 12097-12102
 |  Abstract »  |  Full Text »  |  PDF »

Adapter Protein SH2B1{beta} Cross-Links Actin Filaments and Regulates Actin Cytoskeleton.

L. Rider, J. Tao, S. Snyder, B. Brinley, J. Lu, and M. Diakonova (2009)
Mol. Endocrinol. 23, 1065-1076
 |  Abstract »  |  Full Text »  |  PDF »

The 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Janus kinase 2-signal transducer and activator of transcription-5B-dependent expression of interleukin-8.

S. Y. Cheranov, D. Wang, V. Kundumani-Sridharan, M. Karpurapu, Q. Zhang, K. R. Chava, and G. N. Rao (2009)
Blood 113, 6023-6033
 |  Abstract »  |  Full Text »  |  PDF »

Impaired interferon signaling is a common immune defect in human cancer.

R. J. Critchley-Thorne, D. L. Simons, N. Yan, A. K. Miyahira, F. M. Dirbas, D. L. Johnson, S. M. Swetter, R. W. Carlson, G. A. Fisher, A. Koong, et al. (2009)
PNAS 106, 9010-9015
 |  Abstract »  |  Full Text »  |  PDF »

Perspectives for Cancer Prevention With Natural Compounds.

A.R.M. R. Amin, O. Kucuk, F. R. Khuri, and D. M. Shin (2009)
J. Clin. Oncol. 27, 2712-2725
 |  Abstract »  |  Full Text »  |  PDF »

Unraveling Viral Interleukin-6 Binding to gp130 and Activation of STAT-Signaling Pathways Independently of the Interleukin-6 Receptor.

N. Adam, B. Rabe, J. Suthaus, J. Grotzinger, S. Rose-John, and J. Scheller (2009)
J. Virol. 83, 5117-5126
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-Dependent Engagement of Eukaryotic Initiation Factor 4B via S6 Kinase (S6K)- and Ribosomal Protein S6K-Mediated Signals.

B. Kroczynska, S. Kaur, E. Katsoulidis, B. Majchrzak-Kita, A. Sassano, S. C. Kozma, E. N. Fish, and L. C. Platanias (2009)
Mol. Cell. Biol. 29, 2865-2875
 |  Abstract »  |  Full Text »  |  PDF »

Tristetraprolin Mediates Interferon-{gamma} mRNA Decay.

R. L. Ogilvie, J. R. SternJohn, B. Rattenbacher, I. A. Vlasova, D. A. Williams, H. H. Hau, P. J. Blackshear, and P. R. Bohjanen (2009)
J. Biol. Chem. 284, 11216-11223
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Protein Kinase C{eta} by Type I Interferons.

A. J. Redig, A. Sassano, B. Majchrzak-Kita, E. Katsoulidis, H. Liu, J. K. Altman, E. N. Fish, A. Wickrema, and L. C. Platanias (2009)
J. Biol. Chem. 284, 10301-10314
 |  Abstract »  |  Full Text »  |  PDF »

Role of c-Myb during Prolactin-Induced Signal Transducer and Activator of Transcription 5a Signaling in Breast Cancer Cells.

F. Fang, M. A. Rycyzyn, and C. V. Clevenger (2009)
Endocrinology 150, 1597-1606
 |  Abstract »  |  Full Text »  |  PDF »

Loss of Mandibular Lymph Node Integrity Is Associated with an Increase in Sensitivity to HSV-1 Infection in CD118-Deficient Mice.

C. D. Conrady, M. Thapa, T. Wuest, and D. J. J. Carr (2009)
J. Immunol. 182, 3678-3687
 |  Abstract »  |  Full Text »  |  PDF »

Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2.

I. De Domenico, E. Lo, D. M. Ward, and J. Kaplan (2009)
PNAS 106, 3800-3805
 |  Abstract »  |  Full Text »  |  PDF »

PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts.

T. Hikata, H. Takaishi, J. Takito, A. Hakozaki, M. Furukawa, S. Uchikawa, T. Kimura, Y. Okada, M. Matsumoto, A. Yoshimura, et al. (2009)
Blood 113, 2202-2212
 |  Abstract »  |  Full Text »  |  PDF »

Reovirus {micro}2 Protein Inhibits Interferon Signaling through a Novel Mechanism Involving Nuclear Accumulation of Interferon Regulatory Factor 9.

J. Zurney, T. Kobayashi, G. H. Holm, T. S. Dermody, and B. Sherry (2009)
J. Virol. 83, 2178-2187
 |  Abstract »  |  Full Text »  |  PDF »

A Specific Epitope of Protein Inhibitor of Activated STAT3 Is Responsible for the Induction of Apoptosis in Rat Transformed Mast Cells.

Z. Yagil, G. Kay, H. Nechushtan, and E. Razin (2009)
J. Immunol. 182, 2168-2175
 |  Abstract »  |  Full Text »  |  PDF »

Curcumin Suppresses the Induction of Indoleamine 2,3-Dioxygenase by Blocking the Janus-activated Kinase-Protein Kinase C{delta}-STAT1 Signaling Pathway in Interferon-{gamma}-stimulated Murine Dendritic Cells.

Y.-I. Jeong, S. W. Kim, I. D. Jung, J. S. Lee, J. H. Chang, C.-M. Lee, S. H. Chun, M.-S. Yoon, G. T. Kim, S. W. Ryu, et al. (2009)
J. Biol. Chem. 284, 3700-3708
 |  Abstract »  |  Full Text »  |  PDF »

Missense mutations that cause Van der Woude syndrome and popliteal pterygium syndrome affect the DNA-binding and transcriptional activation functions of IRF6.

H. J. Little, N. K. Rorick, L.-I Su, C. Baldock, S. Malhotra, T. Jowitt, L. Gakhar, R. Subramanian, B. C. Schutte, M. J. Dixon, et al. (2009)
Hum. Mol. Genet. 18, 535-545
 |  Abstract »  |  Full Text »  |  PDF »

Delayed and acute effects of interferon-{gamma} on activity of an inwardly rectifying K+ channel in cultured human proximal tubule cells.

K. Nakamura, Y. Komagiri, T. Kojo, and M. Kubokawa (2009)
Am J Physiol Renal Physiol 296, F46-F53
 |  Abstract »  |  Full Text »  |  PDF »

DNA Methylation Represses IFN-{gamma}-Induced and Signal Transducer and Activator of Transcription 1-Mediated IFN Regulatory Factor 8 Activation in Colon Carcinoma Cells.

J. M. McGough, D. Yang, S. Huang, D. Georgi, S. M. Hewitt, C. Rocken, M. Tanzer, M. P.A. Ebert, and K. Liu (2008)
Mol. Cancer Res. 6, 1841-1851
 |  Abstract »  |  Full Text »  |  PDF »

Ligand-independent Homomeric and Heteromeric Complexes between Interleukin-2 or -9 Receptor Subunits and the {gamma} Chain.

Y. Malka, T. Hornakova, Y. Royer, L. Knoops, J.-C. Renauld, S. N. Constantinescu, and Y. I. Henis (2008)
J. Biol. Chem. 283, 33569-33577
 |  Abstract »  |  Full Text »  |  PDF »

Non-DNA-binding platinum anticancer agents: Cytotoxic activities of platinum-phosphato complexes towards human ovarian cancer cells.

R. N. Bose, L. Maurmann, R. J. Mishur, L. Yasui, S. Gupta, W. S. Grayburn, H. Hofstetter, and T. Salley (2008)
PNAS 105, 18314-18319
 |  Abstract »  |  Full Text »  |  PDF »

Dual Regulatory Roles of Phosphatidylinositol 3-Kinase in IFN Signaling.

S. Kaur, A. Sassano, A. M. Joseph, B. Majchrzak-Kita, E. A. Eklund, A. Verma, S. M. Brachmann, E. N. Fish, and L. C. Platanias (2008)
J. Immunol. 181, 7316-7323
 |  Abstract »  |  Full Text »  |  PDF »

The STAT3 NH2-terminal Domain Stabilizes Enhanceosome Assembly by Interacting with the p300 Bromodomain.

T. Hou, S. Ray, C. Lee, and A. R. Brasier (2008)
J. Biol. Chem. 283, 30725-30734
 |  Abstract »  |  Full Text »  |  PDF »

Activation of signal transducer and activator of transcription 3 correlates with cell proliferation and renal injury in human glomerulonephritis.

T. Arakawa, T. Masaki, T. Hirai, S. Doi, M. Kuratsune, K. Arihiro, N. Kohno, and N. Yorioka (2008)
Nephrol. Dial. Transplant. 23, 3418-3426
 |  Abstract »  |  Full Text »  |  PDF »

Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas.

F. Yang, T. E. Van Meter, R. Buettner, M. Hedvat, W. Liang, C. M. Kowolik, N. Mepani, J. Mirosevich, S. Nam, M. Y. Chen, et al. (2008)
Mol. Cancer Ther. 7, 3519-3526
 |  Abstract »  |  Full Text »  |  PDF »

Hyaluronan-Mediated Leukocyte Adhesion and Dextran Sulfate Sodium-Induced Colitis Are Attenuated in the Absence of Signal Transducer and Activator of Transcription 1.

S. K. Bandyopadhyay, C. A. de la Motte, S. P. Kessler, V. C. Hascall, D. R. Hill, and S. A. Strong (2008)
Am. J. Pathol. 173, 1361-1368
 |  Abstract »  |  Full Text »  |  PDF »

The genetics of SLE: an update in the light of genome-wide association studies.

B. Rhodes and T. J. Vyse (2008)
Rheumatology 47, 1603-1611
 |  Abstract »  |  Full Text »  |  PDF »

IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma.

K. R. Calvo, B. Dabir, A. Kovach, C. Devor, R. Bandle, A. Bond, J. H. Shih, and E. S. Jaffe (2008)
Blood 112, 3818-3826
 |  Abstract »  |  Full Text »  |  PDF »

BDNF Selectively Regulates GABAA Receptor Transcription by Activation of the JAK/STAT Pathway.

I. V. Lund, Y. Hu, Y. H. Raol, R. S. Benham, R. Faris, S. J. Russek, and A. R. Brooks-Kayal (2008)
Science Signaling 1, ra9
 |  Abstract »  |  Full Text »  |  PDF »

Constitutively Activated STAT3 Frequently Coexpresses with Epidermal Growth Factor Receptor in High-Grade Gliomas and Targeting STAT3 Sensitizes Them to Iressa and Alkylators.

H.-W. Lo, X. Cao, H. Zhu, and F. Ali-Osman (2008)
Clin. Cancer Res. 14, 6042-6054
 |  Abstract »  |  Full Text »  |  PDF »

Aberrant expression of BAFF receptor, a member of the tumor necrosis factor receptor family, in malignant cells of nonhematopoietic origins.

T. Kohno, T. Daa, H. Otani, I. Shimokawa, S. Yokoyama, and T. Matsuyama (2008)
Genes Cells 13, 1061-1073
 |  Abstract »  |  Full Text »  |  PDF »

Modelling non-stationary gene regulatory processes with a non-homogeneous Bayesian network and the allocation sampler.

M. Grzegorczyk, D. Husmeier, K. D. Edwards, P. Ghazal, and A. J. Millar (2008)
Bioinformatics 24, 2071-2078
 |  Abstract »  |  Full Text »  |  PDF »

Virus Infection Triggers SUMOylation of IRF3 and IRF7, Leading to the Negative Regulation of Type I Interferon Gene Expression.

T. Kubota, M. Matsuoka, T.-H. Chang, P. Tailor, T. Sasaki, M. Tashiro, A. Kato, and K. Ozato (2008)
J. Biol. Chem. 283, 25660-25670
 |  Abstract »  |  Full Text »  |  PDF »

Prognostic Value of Signal Transducers and Activators of Transcription 3 in Breast Cancer.

S.-M. Sheen-Chen, C.-C. Huang, R.-P. Tang, F.-F. Chou, and H.-L. Eng (2008)
Cancer Epidemiol. Biomarkers Prev. 17, 2286-2290
 |  Abstract »  |  Full Text »  |  PDF »

Requirement of histone deacetylase1 (HDAC1) in signal transducer and activator of transcription 3 (STAT3) nucleocytoplasmic distribution.

S. Ray, C. Lee, T. Hou, I. Boldogh, and A. R. Brasier (2008)
Nucleic Acids Res. 36, 4510-4520
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the JAK/STAT-1 Signaling Pathway by IFN-{gamma} Can Down-Regulate Functional Expression of the MHC Class I-Related Neonatal Fc Receptor for IgG.

X. Liu, L. Ye, Y. Bai, H. Mojidi, N. E. Simister, and X. Zhu (2008)
J. Immunol. 181, 449-463
 |  Abstract »  |  Full Text »  |  PDF »

Genomic dissection of the cytokine-controlled STAT5 signaling network in liver.

A. Hosui and L. Hennighausen (2008)
Physiol Genomics 34, 135-143
 |  Abstract »  |  Full Text »  |  PDF »

Signal transducer and activator of transcription 5A/B in prostate and breast cancers.

S.-H. Tan and M. T Nevalainen (2008)
Endocr. Relat. Cancer 15, 367-390
 |  Abstract »  |  Full Text »  |  PDF »

Methamphetamine Enhances HIV Infection of Macrophages.

H. Liang, X. Wang, H. Chen, L. Song, L. Ye, S.-H. Wang, Y.-J. Wang, L. Zhou, and W.-Z. Ho (2008)
Am. J. Pathol. 172, 1617-1624
 |  Abstract »  |  Full Text »  |  PDF »

Interferon signaling and treatment outcome in chronic hepatitis C.

M. Sarasin-Filipowicz, E. J. Oakeley, F. H. T. Duong, V. Christen, L. Terracciano, W. Filipowicz, and M. H. Heim (2008)
PNAS 105, 7034-7039
 |  Abstract »  |  Full Text »  |  PDF »

Mouse cytomegalovirus inhibits beta interferon (IFN-{beta}) gene expression and controls activation pathways of the IFN-{beta} enhanceosome.

V. T. K. Le, M. Trilling, A. Zimmermann, and H. Hengel (2008)
J. Gen. Virol. 89, 1131-1141
 |  Abstract »  |  Full Text »  |  PDF »

IFP35 Is Involved in the Antiviral Function of Interferon by Association with the Viral Tas Transactivator of Bovine Foamy Virus.

J. Tan, W. Qiao, J. Wang, F. Xu, Y. Li, J. Zhou, Q. Chen, and Y. Geng (2008)
J. Virol. 82, 4275-4283
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Interferon (IFN)-inducible Genes and IFN-mediated Functional Responses in BCR-ABL-expressing Cells.

E. Katsoulidis, A. Sassano, B. Majchrzak-Kita, N. Carayol, P. Yoon, A. Jordan, B. J. Druker, E. N. Fish, and L. C. Platanias (2008)
J. Biol. Chem. 283, 10793-10803
 |  Abstract »  |  Full Text »  |  PDF »

Single-Cell, Phosphoepitope-Specific Analysis Demonstrates Cell Type- and Pathway-Specific Dysregulation of Jak/STAT and MAPK Signaling Associated with In Vivo Human Immunodeficiency Virus Type 1 Infection.

A. W. Lee, E. R. Sharp, A. O'Mahony, M. G. Rosenberg, D. M. Israelski, G. P. Nolan, and D. F. Nixon (2008)
J. Virol. 82, 3702-3712
 |  Abstract »  |  Full Text »  |  PDF »

Leptin-Mediated Hypothalamic Pathway of Cholecystokinin (CCK-8) to Regulate Body Weight in Free-Feeding Rats.

B. Merino, V. Cano, R. Guzman, B. Somoza, and M. Ruiz-Gayo (2008)
Endocrinology 149, 1994-2000
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Akt pathway in mRNA translation of interferon-stimulated genes.

S. Kaur, A. Sassano, B. Dolniak, S. Joshi, B. Majchrzak-Kita, D. P. Baker, N. Hay, E. N. Fish, and L. C. Platanias (2008)
PNAS 105, 4808-4813
 |  Abstract »  |  Full Text »  |  PDF »

BART is essential for nuclear retention of STAT3.

R. Muromoto, Y. Sekine, S. Imoto, O. Ikeda, T. Okayama, N. Sato, and T. Matsuda (2008)
Int. Immunol. 20, 395-403
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{alpha}-2b-Induced Signal Transduction and Gene Regulation in Patient Peripheral Blood Mononuclear Cells Is Not Enhanced by a Dose Increase from 5 to 10 Megaunits/m2.

J. M. Zimmerer, A. M. Lehman, A. S. Ruppert, C. W. Noble, T. Olencki, M. J. Walker, K. Kendra, and W. E. Carson III (2008)
Clin. Cancer Res. 14, 1438-1445
 |  Abstract »  |  Full Text »  |  PDF »

Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension.

S. Mukhopadhyay, M. Shah, F. Xu, K. Patel, R. M. Tuder, and P. B. Sehgal (2008)
Am J Physiol Lung Cell Mol Physiol 294, L449-L468
 |  Abstract »  |  Full Text »  |  PDF »

Negative Feedback Regulation of IFN-{gamma} Pathway by IFN Regulatory Factor 2 in Esophageal Cancers.

Y. Wang, D. Liu, P. Chen, H. P. Koeffler, X. Tong, and D. Xie (2008)
Cancer Res. 68, 1136-1143
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Novel Direct Stat3 Target Genes for Control of Growth and Differentiation.

M. Snyder, X.-Y. Huang, and J. J. Zhang (2008)
J. Biol. Chem. 283, 3791-3798
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway.

N. de la Iglesia, G. Konopka, S. V. Puram, J. A. Chan, R. M. Bachoo, M. J. You, D. E. Levy, R. A. DePinho, and A. Bonni (2008)
Genes & Dev. 22, 449-462
 |  Abstract »  |  Full Text »  |  PDF »

Dual Role of the Jak1 FERM and Kinase Domains in Cytokine Receptor Binding and in Stimulation-Dependent Jak Activation.

S. Haan, C. Margue, A. Engrand, C. Rolvering, H. Schmitz-Van de Leur, P. C. Heinrich, I. Behrmann, and C. Haan (2008)
J. Immunol. 180, 998-1007
 |  Abstract »  |  Full Text »  |  PDF »

Blockage of JAK/STAT signalling attenuates renal ischaemia-reperfusion injury in rats.

N. Yang, M. Luo, R. Li, Y. Huang, R. Zhang, Q. Wu, F. Wang, Y. Li, and X. Yu (2008)
Nephrol. Dial. Transplant. 23, 91-100
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen and Progesterone are Critical Regulators of Stat5a Expression in the Mouse Mammary Gland.

S. J. Santos, S. Z. Haslam, and S. E. Conrad (2008)
Endocrinology 149, 329-338
 |  Abstract »  |  Full Text »  |  PDF »

Basal Expression Levels of IFNAR and Jak-STAT Components Are Determinants of Cell-Type-Specific Differences in Cardiac Antiviral Responses.

J. Zurney, K. E. Howard, and B. Sherry (2007)
J. Virol. 81, 13668-13680
 |  Abstract »  |  Full Text »  |  PDF »

Stat3 Isoforms, {alpha} and , Demonstrate Distinct Intracellular Dynamics with Prolonged Nuclear Retention of Stat3 Mapping to Its Unique C-terminal End.

Y. Huang, J. Qiu, S. Dong, M. S. Redell, V. Poli, M. A. Mancini, and D. J. Tweardy (2007)
J. Biol. Chem. 282, 34958-34967
 |  Abstract »  |  Full Text »  |  PDF »

The Long Form of the Leptin Receptor Regulates STAT5 and Ribosomal Protein S6 via Alternate Mechanisms.

Y. Gong, R. Ishida-Takahashi, E. C. Villanueva, D. C. Fingar, H. Munzberg, and M. G. Myers Jr. (2007)
J. Biol. Chem. 282, 31019-31027
 |  Abstract »  |  Full Text »  |  PDF »

Epidermal Growth Factor Receptor Cooperates with Signal Transducer and Activator of Transcription 3 to Induce Epithelial-Mesenchymal Transition in Cancer Cells via Up-regulation of TWIST Gene Expression.

H.-W. Lo, S.-C. Hsu, W. Xia, X. Cao, J.-Y. Shih, Y. Wei, J. L. Abbruzzese, G. N. Hortobagyi, and M.-C. Hung (2007)
Cancer Res. 67, 9066-9076
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{epsilon} Mediates TNF-{alpha}-Induced STAT1 Phosphorylation and Induction of Retinoic Acid-Inducible Gene-I in Human Cervical Cancer Cells.

T. Matsumiya, S. M. Prescott, and D. M. Stafforini (2007)
J. Immunol. 179, 4542-4549
 |  Abstract »  |  Full Text »  |  PDF »

IFN Regulatory Factor 8 Mediates Apoptosis in Nonhemopoietic Tumor Cells via Regulation of Fas Expression.

D. Yang, M. Thangaraju, D. D. Browning, Z. Dong, B. Korchin, D. C. Lev, V. Ganapathy, and K. Liu (2007)
J. Immunol. 179, 4775-4782
 |  Abstract »  |  Full Text »  |  PDF »

Live cell imaging of interleukin-6-induced targeting of "transcription factor" STAT3 to sequestering endosomes in the cytoplasm.

F. Xu, S. Mukhopadhyay, and P. B. Sehgal (2007)
Am J Physiol Cell Physiol 293, C1374-C1382
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Activation of Signal Transducer and Activator of Transcription-5B Signaling in the Vessel Wall Reduces Balloon Injury-Induced Neointima Formation.

V. Kundumani-Sridharan, D. Wang, M. Karpurapu, Z. Liu, C. Zhang, N. Dronadula, and G. N. Rao (2007)
Am. J. Pathol. 171, 1381-1394
 |  Abstract »  |  Full Text »  |  PDF »

Histone Deacetylase Inhibitors Induce Cell Death Selectively in Cells That Harbor Activated kRasV12: The Role of Signal Transducers and Activators of Transcription 1 and p21.

L. Klampfer, J. Huang, S. Shirasawa, T. Sasazuki, and L. Augenlicht (2007)
Cancer Res. 67, 8477-8485
 |  Abstract »  |  Full Text »  |  PDF »

Chemotactic Effect of Ciliary Neurotrophic Factor on Macrophages in Retinal Ganglion Cell Survival and Axonal Regeneration.

L.-P. Cen, J.-M. Luo, C.-W. Zhang, Y.-M. Fan, Y. Song, K.-F. So, N. van Rooijen, C. P. Pang, D. S. C. Lam, and Q. Cui (2007)
Invest. Ophthalmol. Vis. Sci. 48, 4257-4266
 |  Abstract »  |  Full Text »  |  PDF »

In spermatozoa, Stat1 is activated during capacitation and the acrosomal reaction.

Y. Bastian, A. Zepeda-Bastida, S. Uribe, and A. Mujica (2007)
Reproduction 134, 425-433
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of interleukin-2 signaling by fatty acids in human lymphocytes.

R. Gorjao, S. M. Hirabara, T. M. de Lima, M. F. Cury-Boaventura, and R. Curi (2007)
J. Lipid Res. 48, 2009-2019
 |  Abstract »  |  Full Text »  |  PDF »

PDGF Synergistically Enhances IFN-{gamma}-Induced Expression of CXCL10 in Blood-Derived Macrophages: Implications for HIV Dementia.

N. K. Dhillon, F. Peng, R. M. Ransohoff, and S. Buch (2007)
J. Immunol. 179, 2722-2730
 |  Abstract »  |  Full Text »  |  PDF »

Melanoma Cells Exhibit Variable Signal Transducer and Activator of Transcription 1 Phosphorylation and a Reduced Response to IFN-{alpha} Compared with Immune Effector Cells.

G. B. Lesinski, J. Trefry, M. Brasdovich, S. V. Kondadasula, K. Sackey, J. M. Zimmerer, A. R. Chaudhury, L. Yu, X. Zhang, T. R. Crespin, et al. (2007)
Clin. Cancer Res. 13, 5010-5019
 |  Abstract »  |  Full Text »  |  PDF »

Tissue-Specific and Inducer-Specific Differential Induction of ISG56 and ISG54 in Mice.

F. Terenzi, C. White, S. Pal, B. R. G. Williams, and G. C. Sen (2007)
J. Virol. 81, 8656-8665
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear receptor ERR{alpha} and coactivator PGC-1beta are effectors of IFN-{gamma}-induced host defense.

J. Sonoda, J. Laganiere, I. R. Mehl, G. D. Barish, L.-W. Chong, X. Li, I. E. Scheffler, D. C. Mock, A. R. Bataille, F. Robert, et al. (2007)
Genes & Dev. 21, 1909-1920
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{gamma} Suppresses Cyclooxygenase-2 Promoter Activity by Inhibiting C-Jun and C/EBP{beta} Binding.

W.-G. Deng, A. J. Montero, and K. K. Wu (2007)
Arterioscler Thromb Vasc Biol 27, 1752-1759
 |  Abstract »  |  Full Text »  |  PDF »

Induction of MxA Gene Expression by Influenza A Virus Requires Type I or Type III Interferon Signaling.

D. Holzinger, C. Jorns, S. Stertz, S. Boisson-Dupuis, R. Thimme, M. Weidmann, J.-L. Casanova, O. Haller, and G. Kochs (2007)
J. Virol. 81, 7776-7785
 |  Abstract »  |  Full Text »  |  PDF »

The Interferons: 50 Years after Their Discovery, There Is Much More to Learn.

S. Pestka (2007)
J. Biol. Chem. 282, 20047-20051
 |  Abstract »  |  Full Text »  |  PDF »

Control of specificity and magnitude of NF-{kappa}B and STAT1-mediated gene activation through PIASy and PIAS1 cooperation.

S. Tahk, B. Liu, V. Chernishof, K. A. Wong, H. Wu, and K. Shuai (2007)
PNAS 104, 11643-11648
 |  Abstract »  |  Full Text »  |  PDF »

Epstein-Barr virus induces a distinct form of DNA-bound STAT1 compared with that found in interferon-stimulated B lymphocytes.

J. McLaren, M. Rowe, and P. Brennan (2007)
J. Gen. Virol. 88, 1876-1886
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the signal transducer and activator of transcription-1 in diffuse proliferative lupus nephritis.

L. Martinez-Lostao, J. Ordi-Ros, E. Balada, A. Segarra-Medrano, J. Majo-Masferrer, M. Labrador-Horrillo, and M. Vilardell-Tarres (2007)
Lupus 16, 483-488
 |  Abstract »  |  PDF »

Stat2-Dependent Regulation of MHC Class II Expression.

W. Zhao, E. N. Cha, C. Lee, C. Y. Park, and C. Schindler (2007)
J. Immunol. 179, 463-471
 |  Abstract »  |  Full Text »  |  PDF »

Ubp43 regulates BCR-ABL leukemogenesis via the type 1 interferon receptor signaling.

M. Yan, J.-K. Luo, K. J. Ritchie, I. Sakai, K. Takeuchi, R. Ren, and D.-E. Zhang (2007)
Blood 110, 305-312
 |  Abstract »  |  Full Text »  |  PDF »

IL-21 Promotes Differentiation of Naive CD8 T Cells to a Unique Effector Phenotype.

K. A. Casey and M. F. Mescher (2007)
J. Immunol. 178, 7640-7648
 |  Abstract »  |  Full Text »  |  PDF »

Selective blockade of the inhibitory Fc{gamma} receptor (Fc{gamma}RIIB) in human dendritic cells and monocytes induces a type I interferon response program.

K. M. Dhodapkar, D. Banerjee, J. Connolly, A. Kukreja, E. Matayeva, M. C. Veri, J. V. Ravetch, R. M. Steinman, and M. V. Dhodapkar (2007)
J. Exp. Med. 204, 1359-1369
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products