Science 20 May 1994: Vol. 264. no. 5162, pp. 1152 - 1156 DOI: 10.1126/science.8178175

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Articles

Schistosoma mansoni Antigens Modulate Experimental Allergic Asthma in a Murine Model: a Major Role for CD4+ CD25+ Foxp3+ T Cells Independent of Interleukin-10.

L. G. G. Pacifico, F. A. V. Marinho, C. T. Fonseca, M. M. Barsante, V. Pinho, P. A. Sales-Junior, L. S. Cardoso, M. I. Araujo, E. M. Carvalho, G. D. Cassali, et al. (2009)
Infect. Immun. 77, 98-107
 |  Abstract »  |  Full Text »  |  PDF »

Endotoxin Exposure, CD14, and Allergic Disease: An Interaction between Genes and the Environment.

A. Simpson, S. L. John, F. Jury, R. Niven, A. Woodcock, W. E. R. Ollier, and A. Custovic (2006)
Am. J. Respir. Crit. Care Med. 174, 386-392
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Dissection of Complex Traits.

E. S. Lander and N. J. Schork (2006)
Focus 4, 442
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Carriage of DRB1*13 Is Associated with Increased Posttreatment IgE Levels against Schistosoma mansoni Antigens and Lower Long-Term Reinfection Levels..

M. Booth, M. A. Shaw, D. Carpenter, S. Joseph, N. B. Kabatereine, H. C. Kariuki, J. K. Mwatha, F. M. Jones, B. J. Vennervald, J. H. Ouma, et al. (2006)
J. Immunol. 176, 7112-7118
 |  Abstract »  |  Full Text »  |  PDF »

Th2 cytokine genotypes are associated with a milder form of primary Sjogren's syndrome.

M Pertovaara, J Antonen, and M Hurme (2006)
Ann Rheum Dis 65, 666-670
 |  Abstract »  |  Full Text »  |  PDF »

Helminth-Modified Pulmonary Immune Response Protects Mice from Allergen-Induced Airway Hyperresponsiveness.

N. E. Mangan, N. van Rooijen, A. N. J. McKenzie, and P. G. Fallon (2006)
J. Immunol. 176, 138-147
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IL-9 Promotes but Is Not Necessary for Systemic Anaphylaxis.

L. Knoops, J. Louahed, J. Van Snick, and J.-C. Renauld (2005)
J. Immunol. 175, 335-341
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IgE Generation and Mast Cell Effector Function in Mice Deficient in IL-4 and IL-13.

S. C. Fish, D. D. Donaldson, S. J. Goldman, C. M. M. Williams, and M. T. Kasaian (2005)
J. Immunol. 174, 7716-7724
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The CD14 C-159T polymorphism is not associated with asthma or asthma severity in an Australian adult population.

M-A Kedda, F Lose, D Duffy, E Bell, P J Thompson, and J Upham (2005)
Thorax 60, 211-214
 |  Abstract »  |  Full Text »  |  PDF »

The Inherent Complexities of Gene-Environment Interactions.

E. L. Grigorenko (2005)
J. Gerontol. B. Psychol. Sci. Soc. Sci. 60, 53-64
 |  Abstract »  |  Full Text »  |  PDF »

Susceptibility to neoplastic and non-neoplastic pulmonary diseases in mice: genetic similarities.

A. K. Bauer, A. M. Malkinson, and S. R. Kleeberger (2004)
Am J Physiol Lung Cell Mol Physiol 287, L685-L703
 |  Abstract »  |  Full Text »  |  PDF »

Environmental genomics: a key to understanding biology, pathophysiology and disease.

D. A. Schwartz, J. H. Freedman, and E. A. Linney (2004)
Hum. Mol. Genet. 13, R217-R224
 |  Abstract »  |  Full Text »  |  PDF »

An IL-4R{alpha} Allelic Variant, I50, Acts as a Gain-of-Function Variant Relative to V50 for Stat6, But Not Th2 Differentiation.

L. Stephenson, M. H. Johns, E. Woodward, A. L. Mora, and M. Boothby (2004)
J. Immunol. 173, 4523-4528
 |  Abstract »  |  Full Text »  |  PDF »

Linkage/association study of a locus modulating total serum IgE on chromosome 14q13-24 in families with asthma.

A H Mansur, D T Bishop, S T Holgate, A F Markham, and J F J Morrison (2004)
Thorax 59, 876-882
 |  Abstract »  |  Full Text »  |  PDF »

Signal Transducer and Activator of Transcription 6 Haplotypes and Asthma in the Indian Population.

R. Nagarkatti, C. B-Rao, V. Vijayan, S. K. Sharma, and B. Ghosh (2004)
Am. J. Respir. Cell Mol. Biol. 31, 317-321
 |  Abstract »  |  Full Text »  |  PDF »

Functional Analysis of -571 IL-10 Promoter Polymorphism Reveals a Repressor Element Controlled by Sp1.

J. W. Steinke, E. Barekzi, J. Hagman, and L. Borish (2004)
J. Immunol. 173, 3215-3222
 |  Abstract »  |  Full Text »  |  PDF »

Role of NFAT Proteins in IL13 Gene Transcription in Mast Cells.

S. Monticelli, D. C. Solymar, and A. Rao (2004)
J. Biol. Chem. 279, 36210-36218
 |  Abstract »  |  Full Text »  |  PDF »

Transgenic mice which overproduce Th2 cytokines develop spontaneous atopic dermatitis and asthma.

G. R. Lee and R. A. Flavell (2004)
Int. Immunol. 16, 1155-1160
 |  Abstract »  |  Full Text »  |  PDF »

Lymphomagenesis, Hydronephrosis, and Autoantibodies Result from Dysregulation of IL-9 and Are Differentially Dependent on Th2 Cytokines.

A. J. Lauder, H. E. Jolin, P. Smith, J. G. van den Berg, A. Jones, W. Wisden, K. G. C. Smith, A. Dasvarma, P. G. Fallon, and A. N. J. McKenzie (2004)
J. Immunol. 173, 113-122
 |  Abstract »  |  Full Text »  |  PDF »

Studies of Congenic Lines in the Brown Norway Rat Model of Th2-Mediated Immunopathological Disorders Show That the Aurothiopropanol Sulfonate-Induced Immunological Disorder (Aiid3) Locus on Chromosome 9 Plays a Major Role Compared to Aiid2 on Chromosome 10.

M. Mas, P. Cavailles, C. Colacios, J.-F. Subra, D. Lagrange, M. Calise, M.-O. Christen, P. Druet, L. Pelletier, D. Gauguier, et al. (2004)
J. Immunol. 172, 6354-6361
 |  Abstract »  |  Full Text »  |  PDF »

Genetics and the Dutch Hypothesis.

C E Ruse and S G Parker (2004)
Chronic Respiratory Disease 1, 105-113
 |  Abstract »  |  PDF »

Immunocompetence and Allergy.

S. J. McGeady (2004)
Pediatrics 113, 1107-1113
 |  Abstract »  |  Full Text »  |  PDF »

Mapping Susceptibility Genes for Allergic Diseases.

T. D. Howard, D. A. Meyers, and E. R. Bleecker (2003)
Chest 123 , 363S-368S
 |  Abstract »  |  Full Text »  |  PDF »

Pediatric Asthma: An Approach to Pharmacogenetics Analysis.

S. J. Szefler (2003)
Chest 123 , 434S-438S
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Genetic and Perinatal Risk Factors for Asthma Onset and Severity: A Review and Theoretical Analysis.

M. B. Bracken, K. Belanger, W. O. Cookson, E. Triche, D. C. Christiani, and B. P. Leaderer (2002)
Epidemiol. Rev. 24, 176-189
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A Functional Polymorphism in the RANTES Gene Promoter Is Associated with the Development of Late-Onset Asthma.

N. Hizawa, E. Yamaguchi, S. Konno, Y. Tanino, E. Jinushi, and M. Nishimura (2002)
Am. J. Respir. Crit. Care Med. 166, 686-690
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Association of asthma and total IgE levels with human leucocyte antigen-DR in patients with grass allergy.

G. Woszczek, M.L. Kowalski, and M. Borowiec (2002)
Eur. Respir. J. 20, 79-85
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Asthma Genetics.

W. O. C. Cookson (2002)
Chest 121 , 7S-13S
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Itch, sneeze and wheeze: the genetics of atopic allergy.

A. Sheikh (2002)
J R Soc Med 95, 14-17
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The IL-4 production capability of different strains of naive CD4+ T cells controls the direction of the Th cell response.

R. Yagi, W. Suzuki, N. Seki, M. Kohyama, T. Inoue, T. Arai, and M. Kubo (2002)
Int. Immunol. 14, 1-11
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of a Calcium-Activated Chloride Channel as a Shared Target of Th2 Cytokine Pathways and Its Potential Involvement in Asthma.

Y. Zhou, Q. Dong, J. Louahed, C. Dragwa, D. Savio, M. Huang, C. Weiss, Y. Tomer, M. P. McLane, N. C. Nicolaides, et al. (2001)
Am. J. Respir. Cell Mol. Biol. 25, 486-491
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Association of Polymorphisms in the Interleukin-13 Gene with Asthma and Atopy in a Dutch Population.

T. D. Howard, P. A. Whittaker, A. L. Zaiman, G. H. Koppelman, J. Xu, M. T. Hanley, D. A. Meyers, D. S. Postma, and E. R. Bleecker (2001)
Am. J. Respir. Cell Mol. Biol. 25, 377-384
 |  Abstract »  |  Full Text »  |  PDF »

New insights into the role of cytokines in asthma.

J-C Renauld (2001)
J. Clin. Pathol. 54, 577-589
 |  Abstract »  |  Full Text »  |  PDF »

Meta-analysis for linkage to asthma and atopy in the chromosome 5q31-33 candidate region.

L. J. Palmer, K. C. Barnes, P. R. Burton, H. Chen, W. O.C.M. Cookson, Collaborative Study on the Genetics of Asthma, K. A. Deichmann, R. C. Elston, J. W. Holloway, K. B. Jacobs, et al. (2001)
Hum. Mol. Genet. 10, 891-899
 |  Abstract »  |  Full Text »  |  PDF »

Association of a Promoter Polymorphism of the CD14 Gene and Atopy.

G. H. KOPPELMAN, N. E. REIJMERINK, O. COLIN STINE, T. D. HOWARD, P. A. WHITTAKER, D. A. MEYERS, D. S. POSTMA, and E. R. BLEECKER (2001)
Am. J. Respir. Crit. Care Med. 163, 965-969
 |  Abstract »  |  Full Text »

The Balance Between CD45RChigh and CD45RClow CD4 T Cells in Rats Is Intrinsic to Bone Marrow-Derived Cells and Is Genetically Controlled.

J.-F. Subra, B. Cautain, E. Xystrakis, M. Mas, D. Lagrange, H. van der Heijden, M.-J. van de Gaar, P. Druet, G. J. Fournie, A. Saoudi, et al. (2001)
J. Immunol. 166, 2944-2952
 |  Abstract »  |  Full Text »  |  PDF »

IL-13 Overexpression Predisposes to Anaphylaxis Following Antigen Sensitization.

P. G. Fallon, C. L. Emson, P. Smith, and A. N. J. McKenzie (2001)
J. Immunol. 166, 2712-2716
 |  Abstract »  |  Full Text »  |  PDF »

Functional Expression of IL-9 Receptor by Human Neutrophils from Asthmatic Donors: Role in IL-8 Release.

S. G. Abdelilah, K. Latifa, N. Esra, L. Cameron, L. Bouchaib, N. C. Nicolaides, R. C. Levitt, and Q. Hamid (2001)
J. Immunol. 166, 2768-2774
 |  Abstract »  |  Full Text »  |  PDF »

Allergy and Allergic Diseases- First of Two Parts.

A.B. Kay (2001)
N. Engl. J. Med. 344, 30-37
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T Helper Cell Type 2 Cytokines Coordinately Regulate Immunoglobulin E-Dependent Cysteinyl Leukotriene Production by Human Cord Blood-Derived Mast Cells: Profound Induction of Leukotriene C4 Synthase Expression by Interleukin 4.

F. H. Hsieh, B. K. Lam, J. F. Penrose, K. F. Austen, and J. A. Boyce (2001)
J. Exp. Med. 193, 123-134
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for Genetic Associations between Asthma, Atopy, and Bronchial Hyperresponsiveness . A Study of 8- to 18-Yr-Old Twins.

J. R. CLARKE, M. A. JENKINS, J. L. HOPPER, J. B. CARLIN, C. MAYNE, D. G. CLAYTON, M. F. DALTON, D. P. HOLST, and C. F. ROBERTSON (2000)
Am. J. Respir. Crit. Care Med. 162, 2188-2193
 |  Abstract »  |  Full Text »

Proceedings of the ATS Workshop on Refractory Asthma . Current Understanding, Recommendations, and Unanswered Questions.

S. Wenzel (2000)
Am. J. Respir. Crit. Care Med. 162, 2341-2351
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Genetics of asthma and allergic disease.

W. O.C. Cookson and M. F. Moffatt (2000)
Hum. Mol. Genet. 9, 2359-2364
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative Trait Loci Controlling Allergen-Induced Airway Hyperresponsiveness in Inbred Mice.

S. L. Ewart, D. Kuperman, E. Schadt, C. Tankersley, A. Grupe, D. M. Shubitowski, G. Peltz, and M. Wills-Karp (2000)
Am. J. Respir. Cell Mol. Biol. 23, 537-545
 |  Abstract »  |  Full Text »

A first trial of retrospective collaboration for positional cloning in complex inheritance: Assay of the cytokine region on chromosome 5 by the Consortium on Asthma Genetics (COAG).

C. Lonjou, K. Barnes, H. Chen, W. O. C. M. Cookson, K. A. Deichmann, I. P. Hall, J. W. Holloway, T. Laitinen, L. J. Palmer, M. Wjst, et al. (2000)
PNAS 97, 10942-10947
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-9 enhances interleukin-5 receptor expression, differentiation, and survival of human eosinophils.

A. S. Gounni, B. Gregory, E. Nutku, F. Aris, K. Latifa, E. Minshall, J. North, J. Tavernier, R. Levit, N. Nicolaides, et al. (2000)
Blood 96, 2163-2171
 |  Abstract »  |  Full Text »  |  PDF »

Genomic Approaches to Understanding Asthma.

L. J. Palmer and W. O.C.M. Cookson (2000)
Genome Res. 10, 1280-1287
 |  Abstract »  |  Full Text »

Viruses and Atopic Sensitization in the First Years of Life.

F. D. MARTINEZ (2000)
Am. J. Respir. Crit. Care Med. 162, S95-99
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Immune Parameters in High-risk Atopic Individuals during Early Childhood.

H. F. J. SAVELKOUL (2000)
Am. J. Respir. Crit. Care Med. 162, S100-104
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The Genetics of Atopy and Airway Hyperresponsiveness.

D. S. POSTMA, G. H. KOPPELMAN, and D. A. MEYERS (2000)
Am. J. Respir. Crit. Care Med. 162, S118-123
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beta 2-Adrenergic Receptor Arg16/Arg16 Genotype Is Associated with Reduced Lung Function, but Not with Asthma, in the Hutterites.

E. SUMMERHILL, S. A. LEAVITT, H. GIDLEY, R. PARRY, J. SOLWAY, and C. OBER (2000)
Am. J. Respir. Crit. Care Med. 162, 599-602
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Mapping of Two Murine Loci that Influence the Development of IL-4-Producing Thy-1dull {gamma}{delta} Thymocytes.

V. Azuara and P. Pereira (2000)
J. Immunol. 165, 42-48
 |  Abstract »  |  Full Text »  |  PDF »

Independent Inheritance of Serum Immunoglobulin E Concentrations and Airway Responsiveness.

L. J. PALMER, P. R. BURTON, J. A. FAUX, A. L. JAMES, A. WILLIAM MUSK, and W. O. C. M. COOKSON (2000)
Am. J. Respir. Crit. Care Med. 161, 1836-1843
 |  Abstract »  |  Full Text »

Polymorphisms of the IL-4, TNF-alpha , and Fcalpha RIbeta Genes and the Risk of Allergic Disorders in At-risk Infants.

S. ZHU, M. CHAN-YEUNG, A. B. BECKER, H. DIMICH-WARD, A. C. FERGUSON, J. MANFREDA, W. T. A. WATSON, P. D. PARÉ, and A. J. SANDFORD (2000)
Am. J. Respir. Crit. Care Med. 161, 1655-1659
 |  Abstract »  |  Full Text »

Baseline Airway Hyperreactivity in A/J Mice Is not Mediated by Cells of the Adaptive Immune System.

H. Hadeiba, D. B. Corry, and R. M. Locksley (2000)
J. Immunol. 164, 4933-4940
 |  Abstract »  |  Full Text »  |  PDF »

Genetic variants of IL-13 signalling and human asthma and atopy.

A. Heinzmann, X.-Q. Mao, M. Akaiwa, R.T. Kreomer, P.-S. Gao, K. Ohshima, R. Umeshita, Y. Abe, S. Braun, T. Yamashita, et al. (2000)
Hum. Mol. Genet. 9, 549-559
 |  Abstract »  |  Full Text »  |  PDF »

The Genetics of Asthma . The Important Questions.

A. J. SANDFORD and P. D. PARE (2000)
Am. J. Respir. Crit. Care Med. 161, S202-206
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Anti-IL-9 vaccination prevents worm expulsion and blood eosinophilia in Trichuris muris-infected mice.

M. Richard, R. K. Grencis, N. E. Humphreys, J.-C. Renauld, and J. Van Snick (2000)
PNAS 97, 767-772
 |  Abstract »  |  Full Text »  |  PDF »

Soluble IL-4 Receptor Inhibits Airway Inflammation Following Allergen Challenge in a Mouse Model of Asthma.

W. R. Henderson Jr., E. Y. Chi, and C. R. Maliszewski (2000)
J. Immunol. 164, 1086-1095
 |  Abstract »  |  Full Text »  |  PDF »

AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23).

T. Taki, H. Kano, M. Taniwaki, M. Sako, M. Yanagisawa, and Y. Hayashi (1999)
PNAS 96, 14535-14540
 |  Abstract »  |  Full Text »  |  PDF »

Polymorphism in the IL-13 Promoter.

T. C. d. P. Kraan, L. A. Aarden, C. L. Verweij;, K. M. Gillespie, K. L. Anderson, and P. W. Mathieson; (1999)
Science 286, 1647b-1647
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Genetic Evidence for Lyn as a Negative Regulator of IL-4 Signaling.

M. L. Janas, P. Hodgkin, M. Hibbs, and D. Tarlinton (1999)
J. Immunol. 163, 4192-4198
 |  Abstract »  |  Full Text »  |  PDF »

Association Between a Sequence Variant in the IL-4 Gene Promoter and FEV1 in Asthma.

E. G. BURCHARD, E. K. SILVERMAN, L. J. ROSENWASSER, L. BORISH, C. YANDAVA, A. PILLARI, S. T. WEISS, J. HASDAY, C. M. LILLY, J. G. FORD, et al. (1999)
Am. J. Respir. Crit. Care Med. 160, 919-922
 |  Abstract »  |  Full Text »

T Helper Cell Type 2 Cytokine-Mediated Comitogenic Responses and Ccr3 Expression during Differentiation of Human Mast Cells in Vitro.

H. Ochi, W. M. Hirani, Q. Yuan, D. S. Friend, K. F. Austen, and J. A. Boyce (1999)
J. Exp. Med. 190, 267-280
 |  Abstract »  |  Full Text »  |  PDF »

Suggestive Evidence for Genetic Linkage Between IgE Phenotypes and Chromosome 14q Markers.

A. H. MANSUR, D. T. BISHOP, A. F. MARKHAM, N. E. MORTON, S. T. HOLGATE, and J. F. J. MORRISON (1999)
Am. J. Respir. Crit. Care Med. 159, 1796-1802
 |  Abstract »  |  Full Text »

Polymorphisms Not Found in the IL-13 Gene Promoter.

K. L. Anderson, P. W. Mathieson, K. M. Gillespie;, M. Wills-Karp, and L. J. Rosenwasser; (1999)
Science 284, 1431a-1431
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Simultaneous Disruption of Interleukin (IL)-4 and IL-13 Defines Individual Roles in T Helper Cell Type 2-mediated Responses.

G. J. McKenzie, P. G. Fallon, C. L. Emson, R. K. Grencis, and A. N.J. McKenzie (1999)
J. Exp. Med. 189, 1565-1572
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 9-induced In Vivo Expansion of the B-1 Lymphocyte Population.

A. Vink, G. Warnier, F. Brombacher, and J.-C. Renauld (1999)
J. Exp. Med. 189, 1413-1423
 |  Abstract »  |  Full Text »  |  PDF »

A Polymorphism* in the 5' Flanking Region of the CD14 Gene Is Associated with Circulating Soluble CD14 Levels and with Total Serum Immunoglobulin E.

M. Baldini, I. Carla Lohman, M. Halonen, R. P. Erickson, P. G. Holt, and F. D. Martinez (1999)
Am. J. Respir. Cell Mol. Biol. 20, 976-983
 |  Abstract »  |  Full Text »

Cutting Edge: Effects of an Allergy-Associated Mutation in the Human IL-4R{alpha} (Q576R) on Human IL-4-Induced Signal Transduction.

H. Y. Wang, C. P. Shelburne, J. Zamorano, A. E. Kelly, J. J. Ryan, and A. D. Keegan (1999)
J. Immunol. 162, 4385-4389
 |  Abstract »  |  Full Text »  |  PDF »

A Genome-Wide Search Identifies Two Susceptibility Loci for Experimental Autoimmune Encephalomyelitis on Rat Chromosomes 4 and 10.

M.-P. Roth, C. Viratelle, L. Dolbois, M. Delverdier, N. Borot, L. Pelletier, P. Druet, M. Clanet, and H. Coppin (1999)
J. Immunol. 162, 1917-1922
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for suppressed activity of the transcription factor NFAT1 at its proximal binding element P0 in the IL-4 promoter associated with enhanced IL-4 gene transcription in T cells of atopic patients.

E. A. Wierenga, M. Walchner, G. Kick, M. L. Kapsenberg, E. H. Weiss, and G. Messer (1999)
Int. Immunol. 11, 297-306
 |  Abstract »  |  Full Text »  |  PDF »

Tpm1, a Locus Controlling IL-12 Responsiveness, Acts by a Cell-Autonomous Mechanism.

M. L. Guler, J. D. Gorham, W. F. Dietrich, T. L. Murphy, R. G. Steen, C. A. Parvin, D. Fenoglio, A. Grupe, G. Peltz, and K. M. Murphy (1999)
J. Immunol. 162, 1339-1347
 |  Abstract »  |  Full Text »  |  PDF »

Asthma, Wheezy Bronchitis, and Atopy across Two Generations.

G. L. CHRISTIE, P. J. HELMS, D. J. GODDEN, S. J. ROSS, J. A. R. FRIEND, J. S. LEGGE, N. E. HAITES, and J. G. DOUGLAS (1999)
Am. J. Respir. Crit. Care Med. 159, 125-129
 |  Abstract »  |  Full Text »

Genetics and pulmonary medicine bullet  8: Genetics and pulmonary medicine: asthma.

I P Hall (1999)
Thorax 54, 65-69
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Linkage of Chromosome 5q and 11q Gene Markers to Asthma-associated Quantitative Traits in Australian Children.

L. J. PALMER, S. E. DANIELS, P. J. RYE, N. A. GIBSON, G. K. TAY, W. O. C. M. COOKSON, J. GOLDBLATT, P. R. BURTON, and P. N. LESOUEF (1998)
Am. J. Respir. Crit. Care Med. 158, 1825-1830
 |  Abstract »  |  Full Text »  |  PDF »

Role of T-helper type 2 cytokines in down-modulation of Fas mRNA and receptor on the surface of activated CD4+ T cells: molecular basis for the persistence of the allergic immune response.

F. Spinozzi, E. Agea, M. Fizzotti, G. Bassotti, A. Russano, S. Droetto, O. Bistoni, F. Grignani, and A. Bertotto (1998)
FASEB J 12, 1747-1753
 |  Abstract »  |  Full Text »

Expression of Interleukin 9 in the Lungs of Transgenic Mice Causes Airway Inflammation, Mast Cell Hyperplasia, and Bronchial Hyperresponsiveness.

U.-A. Temann, G. P. Geba, J. A. Rankin, and R. A. Flavell (1998)
J. Exp. Med. 188, 1307-1320
 |  Abstract »  |  Full Text »  |  PDF »

Novel Diversity in Th1, Th2 Type Differentiation of Hemagglutinin-Specific T Cell Clones Elicited by Natural Influenza Virus Infection in Three Major Haplotypes (H-2b,d,k).

C. M. Graham, C. A. Smith, and D. B. Thomas (1998)
J. Immunol. 161, 1094-1103
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Epitopes in Japanese Cedar (Cryptomeria japonica) Pollen Allergens: Choice of Major T Cell Epitopes in Cry j 1 and Cry j 2 Toward Design of the Peptide-Based Immunotherapeutics for the Management of Japanese Cedar Pollinosis.

T. Sone, K. Morikubo, M. Miyahara, N. Komiyama, K. Shimizu, H. Tsunoo, and K. Kino (1998)
J. Immunol. 161, 448-457
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Eosinophilia.

M. E. Rothenberg (1998)
N. Engl. J. Med. 338, 1592-1600
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Genetic Control of Immune Response to Recombinant Antigens Carried by an Attenuated Salmonella typhimurium Vaccine Strain: Nramp1 Influences T-Helper Subset Responses and Protection against Leishmanial Challenge.

S.-S. Soo, B. Villarreal-Ramos, C. M. A. Khan, C. E. Hormaeche, and J. M. Blackwell (1998)
Infect. Immun. 66, 1910-1917
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Molecular biology and genetics of allergy and asthma.

G G Anderson and J F J Morrison (1998)
Arch. Dis. Child. 78, 488-496
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Importance of Genetic Factors in Adolescent Asthma . A Population-based Twin-family Study.

T. LAITINEN, M. RASANEN, J. KAPRIO, M. KOSKENVUO, and L. A. LAITINEN (1998)
Am. J. Respir. Crit. Care Med. 157, 1073-1078
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Recent advances: Immunology.

M. Kemeny and M. Peakman (1998)
BMJ 316, 600-603
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The Association of Atopy with a Gain-of-Function Mutation in the {alpha} Subunit of the Interleukin-4 Receptor.

G. K. K. Hershey, M. F. Friedrich, L. A. Esswein, M. L. Thomas, and T. A. Chatila (1997)
N. Engl. J. Med. 337, 1720-1725
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Interleukin-4 and the Genetics of Atopy.

L. J. Rosenwasser (1997)
N. Engl. J. Med. 337, 1766-1767
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Asthma.

R. F. Lemanske Jr and W. W. Busse (1997)
JAMA 278, 1855-1873
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Evidence for Linkage Between Asthma/Atopy in Childhood and Chromosome 5q31-q33 in a Japanese Population.

E. NOGUCHI, M. SHIBASAKI, T. ARINAMI, K. TAKEDA, T. MAKI, T. MIYAMOTO, T. KAWASHIMA, K. KOBAYASHI, and H. HAMAGUCHI (1997)
Am. J. Respir. Crit. Care Med. 156, 1390-1393
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HLA Class II Genes in Soybean Epidemic Asthma Patients.

J. B. SORIANO, G. ERCILLA, J. SUNYER, F. X. REAL, C. LÁZARO, M. J. RODRIGO, X. ESTIVILL, J. ROCA, R. RODRÍGUEZ-ROISÍN, F. MORELL, et al. (1997)
Am. J. Respir. Crit. Care Med. 156, 1394-1398
 |  Abstract »  |  Full Text »

Evidence for Multiple Genetic Susceptibility Loci for Asthma.

E. R. BLEECKER, D. S. POSTMA, and D. A. MEYERS (1997)
Am. J. Respir. Crit. Care Med. 156, S113-S116
 |  Abstract »  |  Full Text »  |  PDF »

Epidemiological Study of the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and Atopy . Phenotype Issues.

F. KAUFFMANN, M.-H. DIZIER, I. PIN, E. PATY, F. GORMAND, D. VERVLOET, J. BOUSQUET, F. NEUKIRCH, I. ANNESI, M.-P. ORYSZCZYN, et al. (1997)
Am. J. Respir. Crit. Care Med. 156, S123-S129
 |  Abstract »  |  Full Text »  |  PDF »

Approaches toward the Genetic Analysis of Complex Traits . Asthma and Atopy.

D. G. MARSH (1997)
Am. J. Respir. Crit. Care Med. 156, S133-S138
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Genetics of Atopy and Asthma: The Rationale behind Promoter-based Candidate Gene Studies (IL-4 and IL-10).

L. J. ROSENWASSER and L. BORISH (1997)
Am. J. Respir. Crit. Care Med. 156, S152-S155
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Growth and Development on Lung Function . Models for Study of Childhood Asthma.

W. W. BUSSE, S. P. BANKS-SCHLEGEL, and G. L. LARSEN (1997)
Am. J. Respir. Crit. Care Med. 156, 314-319
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Computational and Biological Analysis of 680 kb of DNA Sequence from the Human 5q31 Cytokine Gene Cluster Region.

K. A. Frazer, Y. Ueda, Y. Zhu, V. R. Gifford, M. R. Garofalo, N. Mohandas, C. H. Martin, M. J. Palazzolo, J.-F. Cheng, and E. M. Rubin (1997)
Genome Res. 7, 495-512
 |  Abstract »  |  Full Text »  |  PDF »

Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis a virus.

P. M Matricardi, F. Rosmini, L. Ferrigno, R. Nisini, M. Rapicetta, P. Chionne, T. Stroffolini, P. Pasquini, and R. D'Amelio (1997)
BMJ 314, 999
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Allergy and Immunology.

J. R. Baker Jr and J. L. Baldwin (1996)
JAMA 275, 1794-1795
 |  Abstract »  |  PDF »

Genetic Susceptibility to Asthma -- Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy.

D. S. Postma, E. R. Bleecker, P. J. Amelung, K. J. Holroyd, J. Xu, C. I.M. Panhuysen, D. A. Meyers, and R. C. Levitt (1995)
N. Engl. J. Med. 333, 894-900
 |  Abstract »  |  Full Text »  |  PDF »

Fc(epsilon)RI-(beta) polymorphism and risk of atopy in a general population sample.

M R Hill, A L James, J A Faux, G Ryan, J M Hopkin, P le Souef, A W Musk, and W O C M Cookson (1995)
BMJ 311, 776-779
 |  Abstract »  |  Full Text »

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