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Science 22 April 1994:
Vol. 264. no. 5158, pp. 572 - 575
DOI: 10.1126/science.8160014
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Articles

Science, Vol 264, Issue 5158, 572-575
Copyright © 1994 by American Association for the Advancement of Science

articles

Bacillus subtilis spoIIIE protein required for DNA segregation during asymmetric cell division

LJ Wu and J Errington

Sir William Dunn School of Pathology, University of Oxford, UK.

Sporulation in Bacillus subtilis begins with an asymmetric cell division, producing a smaller prespore and a larger mother cell, both of which contain intact copies of the chromosome. The spoIIIE gene is required for chromosome segregation into the prespore compartment. The effects of the spoIIIE36 mutation on sigma F-dependent transcription are an indirect consequence of the failure of certain genes to enter the cellular compartment in which their transcription factor has become active. SpoIIIE may also be required to prevent sigma F from becoming active in the mother cell.


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   Abstract »    Full Text »
Prespore-specific gene expression in Bacillus subtilis is driven by sequestration of SpoIIE phosphatase to the prespore side of the asymmetric septum.
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   Abstract »    Full Text »
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Dynamic, mitotic-like behavior of a bacterial protein required for accurate chromosome partitioning..
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   Abstract »    PDF »
Bipolar localization of a chromosome partition protein in Bacillus subtilis.
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Establishment of Cell Type in a Primitive Organism by Cell-specific Elimination and Proteolytic Activation of a Transcription Factor.
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Cold Spring Harb Symp Quant Biol 62, 49-55
   Abstract »    PDF »
Localization of Protein Implicated in Establishment of Cell Type to Sites of Asymmetric Division.
F. Arigoni, K. Pogliano, C. D. Webb, P. Stragier, and R. Losick (1995)
Science 270, 637-640
   Abstract »    PDF »
A conjugation-like mechanism for prespore chromosome partitioning during sporulation in Bacillus subtilis..
L J Wu, P J Lewis, R Allmansberger, P M Hauser, and J Errington (1995)
Genes & Dev. 9, 1316-1326
   Abstract »    PDF »
Cell-cell signaling pathway activating a developmental transcription factor in Bacillus subtilis..
J A Londono-Vallejo and P Stragier (1995)
Genes & Dev. 9, 503-508
   Abstract »    PDF »
Effects of replication termination mutants on chromosome partitioning in Bacillussubtilis.
K. P. Lemon, I. Kurtser, and A. D. Grossman (2001)
PNAS 98, 212-217
   Abstract »    Full Text »    PDF »
Development of a two-part transcription probe to determine the completeness of temporal and spatial compartmentalization of gene expression during bacterial development.
Z. Li and P. J. Piggot (2001)
PNAS 98, 12538-12543
   Abstract »    Full Text »    PDF »


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