Science 22 April 1994: Vol. 264. no. 5158, pp. 569 - 571 DOI: 10.1126/science.7512751

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Articles

Alternatively spliced tissue factor induces angiogenesis through integrin ligation.

Y. W. van den Berg, L. G. van den Hengel, H. R. Myers, O. Ayachi, E. Jordanova, W. Ruf, C. A. Spek, P. H. Reitsma, V. Y. Bogdanov, and H. H. Versteeg (2009)
PNAS 106, 19497-19502
 |  Abstract »  |  Full Text »  |  PDF »

{beta}3-Integrin Expression on Tumor Cells Inhibits Tumor Progression, Reduces Metastasis, and Is Associated with a Favorable Prognosis in Patients with Ovarian Cancer.

S. Kaur, H. A. Kenny, S. Jagadeeswaran, M. R. Zillhardt, A. G. Montag, E. Kistner, S. D. Yamada, A. K. Mitra, and E. Lengyel (2009)
Am. J. Pathol. 175, 2184-2196
 |  Abstract »  |  Full Text »  |  PDF »

Sphingosine Kinase-1 Associates with Integrin {alpha}V{beta}3 to Mediate Endothelial Cell Survival.

J. R. Gamble, W. Y. Sun, X. Li, C. N. Hahn, S. M. Pitson, M. A. Vadas, and C. S. Bonder (2009)
Am. J. Pathol. 175, 2217-2225
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of {alpha}v{beta}3 Integrin-Targeted Positron Emission Tomography Tracer 18F-Galacto-RGD for Imaging of Vascular Inflammation in Atherosclerotic Mice.

I. Laitinen, A. Saraste, E. Weidl, T. Poethko, A. W. Weber, S. G. Nekolla, P. Leppanen, S. Yla-Herttuala, G. Holzlwimmer, A. Walch, et al. (2009)
Circ Cardiovasc Imaging 2, 331-338
 |  Abstract »  |  Full Text »  |  PDF »

Activation of tumor cell integrin {alpha}v{beta}3 controls angiogenesis and metastatic growth in the brain.

M. Lorger, J. S. Krueger, M. O'Neal, K. Staflin, and B. Felding-Habermann (2009)
PNAS 106, 10666-10671
 |  Abstract »  |  Full Text »  |  PDF »

Polymeric micelles from poly(ethylene glycol)-poly(amino acid) block copolymer for drug and gene delivery.

K. Osada, R. J. Christie, and K. Kataoka (2009)
J R Soc Interface 6, S325-S339
 |  Abstract »  |  Full Text »  |  PDF »

Rifampicin as an Oral Angiogenesis Inhibitor Targeting Hepatic Cancers.

M. Shichiri, N. Fukai, Y. Kono, and Y. Tanaka (2009)
Cancer Res. 69, 4760-4768
 |  Abstract »  |  Full Text »  |  PDF »

Integrin {alpha}{nu}{beta}3 is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase {beta}/{zeta}.

C. Mikelis, E. Sfaelou, M. Koutsioumpa, N. Kieffer, and E. Papadimitriou (2009)
FASEB J 23, 1459-1469
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Imaging of Tumor Blood Vessels in Prostate Cancer.

D. TILKI, M. SEITZ, B. B. SINGER, S. IRMAK, C. G. STIEF, O. REICH, and S. ERGUN (2009)
Anticancer Res 29, 1823-1829
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Biphasic Role for Genistein in the Regulation of Prostate Cancer Growth and Metastasis.

L. H. El Touny and P. P. Banerjee (2009)
Cancer Res. 69, 3695-3703
 |  Abstract »  |  Full Text »  |  PDF »

111In-LLP2A-DOTA Polyethylene Glycol-Targeting {alpha}4{beta}1 Integrin: Comparative Pharmacokinetics for Imaging and Therapy of Lymphoid Malignancies.

S. J. DeNardo, R. Liu, H. Albrecht, A. Natarajan, J. L. Sutcliffe, C. Anderson, L. Peng, R. Ferdani, S. R. Cherry, and K. S. Lam (2009)
J. Nucl. Med. 50, 625-634
 |  Abstract »  |  Full Text »  |  PDF »

Syndecan-1 regulates {alpha}v{beta}3 and {alpha}v{beta}5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor.

D. M. Beauvais, B. J. Ell, A. R. McWhorter, and A. C. Rapraeger (2009)
J. Exp. Med. 206, 691-705
 |  Abstract »  |  Full Text »  |  PDF »

Engineered Knottin Peptides: A New Class of Agents for Imaging Integrin Expression in Living Subjects.

R. H. Kimura, Z. Cheng, S. S. Gambhir, and J. R. Cochran (2009)
Cancer Res. 69, 2435-2442
 |  Abstract »  |  Full Text »  |  PDF »

Anti-angiogenic effects of green tea catechin on an experimental endometriosis mouse model.

H. Xu, W.T. Lui, C.Y. Chu, P.S. Ng, C.C. Wang, and M.S. Rogers (2009)
Hum. Reprod. 24, 608-618
 |  Abstract »  |  Full Text »  |  PDF »

Multimodality Cardiovascular Molecular Imaging, Part II.

M. Nahrendorf, D. E. Sosnovik, B. A. French, F. K. Swirski, F. Bengel, M. M. Sadeghi, J. R. Lindner, J. C. Wu, D. L. Kraitchman, Z. A. Fayad, et al. (2009)
Circ Cardiovasc Imaging 2, 56-70
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The angiogenic response is dictated by {beta}3 integrin on bone marrow-derived cells.

W. Feng, N. P. McCabe, G. H. Mahabeleshwar, P. R. Somanath, D. R. Phillips, and T. V. Byzova (2008)
J. Cell Biol. 183, 1145-1157
 |  Abstract »  |  Full Text »  |  PDF »

{alpha}v{beta}3 Integrin-dependent antiangiogenic activity of resveratrol stereoisomers.

M. Belleri, D. Ribatti, M. Savio, L. A. Stivala, L. Forti, E. Tanghetti, P. Alessi, D. Coltrini, A. Bugatti, S. Mitola, et al. (2008)
Mol. Cancer Ther. 7, 3761-3770
 |  Abstract »  |  Full Text »  |  PDF »

Fluorescence Reflectance Imaging of Macrophage-Rich Atherosclerotic Plaques Using an {alpha}v{beta}3 Integrin-Targeted Fluorochrome.

J. Waldeck, F. Hager, C. Holtke, C. Lanckohr, A. von Wallbrunn, G. Torsello, W. Heindel, G. Theilmeier, M. Schafers, and C. Bremer (2008)
J. Nucl. Med. 49, 1845-1851
 |  Abstract »  |  Full Text »  |  PDF »

Functional analysis of the cytoplasmic domain of the integrin {alpha}1 subunit in endothelial cells.

T. D. Abair, N. Bulus, C. Borza, M. Sundaramoorthy, R. Zent, and A. Pozzi (2008)
Blood 112, 3242-3254
 |  Abstract »  |  Full Text »  |  PDF »

Rab-coupling protein coordinates recycling of {alpha}5{beta}1 integrin and EGFR1 to promote cell migration in 3D microenvironments.

P. T. Caswell, M. Chan, A. J. Lindsay, M. W. McCaffrey, D. Boettiger, and J. C. Norman (2008)
J. Cell Biol. 183, 143-155
 |  Abstract »  |  Full Text »  |  PDF »

Integrins: The Keys to Unlocking Angiogenesis.

R. Silva, G. D'Amico, K. M. Hodivala-Dilke, and L. E. Reynolds (2008)
Arterioscler Thromb Vasc Biol 28, 1703-1713
 |  Abstract »  |  Full Text »  |  PDF »

Capillary Sprout Endothelial Cells Exhibit a CD36low Phenotype: Regulation by Shear Stress and Vascular Endothelial Growth Factor-Induced Mechanism for Attenuating Anti-Proliferative Thrombospondin-1 Signaling.

C. R. Anderson, N. E. Hastings, B. R. Blackman, and R. J. Price (2008)
Am. J. Pathol. 173, 1220-1228
 |  Abstract »  |  Full Text »  |  PDF »

Radionuclide imaging a molecular key to the atherosclerotic plaque..

H. F. Langer, R. Haubner, B. J. Pichler, and M. Gawaz (2008)
J. Am. Coll. Cardiol. 52, 1-12
 |  Abstract »  |  Full Text »  |  PDF »

The Future of Cardiovascular Imaging in the Diagnosis and Management of Heart Failure, Part 1: Tasks and Tools.

T. H. Marwick and M. Schwaiger (2008)
Circ Cardiovasc Imaging 1, 58-69
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Antimigratory effect of TK1-2 is mediated in part by interfering with integrin {alpha}2{beta}1.

H.-K. Kim, D.-S. Oh, S.-B. Lee, J.-M. Ha, and Y. A. Joe (2008)
Mol. Cancer Ther. 7, 2133-2141
 |  Abstract »  |  Full Text »  |  PDF »

Direct Binding of Integrin {alpha}v{beta}3 to FGF1 Plays a Role in FGF1 Signaling.

S. Mori, C.-Y. Wu, S. Yamaji, J. Saegusa, B. Shi, Z. Ma, Y. Kuwabara, K. S. Lam, R. R. Isseroff, Y. K. Takada, et al. (2008)
J. Biol. Chem. 283, 18066-18075
 |  Abstract »  |  Full Text »  |  PDF »

Targeted imaging of hypoxia-induced integrin activation in myocardium early after infarction.

L. Kalinowski, L. W. Dobrucki, D. F. Meoli, D. P. Dione, M. M. Sadeghi, J. A. Madri, and A. J. Sinusas (2008)
J Appl Physiol 104, 1504-1512
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Angiogenic Mediators Are Required for Basic Fibroblast Growth Factor- and Vascular Endothelial Growth Factor-induced Angiogenesis: The Role of Cytoplasmic Tyrosine Kinase c-Abl in Tumor Angiogenesis.

W. Yan, B. Bentley, and R. Shao (2008)
Mol. Biol. Cell 19, 2278-2288
 |  Abstract »  |  Full Text »  |  PDF »

Assessment of {alpha}v{beta}3 integrin expression after myocardial infarction by positron emission tomography.

T. Higuchi, F. M. Bengel, S. Seidl, P. Watzlowik, H. Kessler, R. Hegenloh, S. Reder, S. G. Nekolla, H. J. Wester, and M. Schwaiger (2008)
Cardiovasc Res 78, 395-403
 |  Abstract »  |  Full Text »  |  PDF »

Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.

S. M. Weis, S.-T. Lim, K. M. Lutu-Fuga, L. A. Barnes, X. L. Chen, J. R. Gothert, T.-L. Shen, J.-L. Guan, D. D. Schlaepfer, and D. A. Cheresh (2008)
J. Cell Biol. 181, 43-50
 |  Abstract »  |  Full Text »  |  PDF »

Streptococcal Pyrogenic Exotoxin B-Induced Apoptosis in A549 Cells Is Mediated through {alpha}v{beta}3 Integrin and Fas.

W.-H. Tsai, C.-W. Chang, Y.-S. Lin, W.-J. Chuang, J.-J. Wu, C.-C. Liu, P.-J. Tsai, and M. T. Lin (2008)
Infect. Immun. 76, 1349-1357
 |  Abstract »  |  Full Text »  |  PDF »

Integrins and Matrix in the Glomerulus: Old Mysteries and New Insights.

J. A. Kreidberg (2008)
J. Am. Soc. Nephrol. 19, 650-651
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{alpha}2{beta}1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner.

Z. Zhang, N. E. Ramirez, T. E. Yankeelov, Z. Li, L. E. Ford, Y. Qi, A. Pozzi, and M. M. Zutter (2008)
Blood 111, 1980-1988
 |  Abstract »  |  Full Text »  |  PDF »

Integrin {alpha}V 3 Binds to the RGD Motif of Glycoprotein B of Kaposi's Sarcoma-Associated Herpesvirus and Functions as an RGD-Dependent Entry Receptor.

H. J. Garrigues, Y. E. Rubinchikova, C. M. DiPersio, and T. M. Rose (2008)
J. Virol. 82, 1570-1580
 |  Abstract »  |  Full Text »  |  PDF »

Targeting the Tumor Vasculature to Improve the Efficacy of Oncolytic Virus Therapy.

J. H. Rhim and G. Tosato (2007)
J Natl Cancer Inst 99, 1739-1741
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Angiogenesis Inhibition and Choroidal Neovascularization Suppression by Sustained Delivery of an Integrin Antagonist, EMD478761.

Y. Fu, M. L. Ponce, M. Thill, P. Yuan, N. S. Wang, and K. G. Csaky (2007)
Invest. Ophthalmol. Vis. Sci. 48, 5184-5190
 |  Abstract »  |  Full Text »  |  PDF »

Angiogenesis Inhibitors and the Need for Anti-angiogenic Therapeutics.

C.R. Dass, T.M.N. Tran, and P.F.M. Choong (2007)
Journal of Dental Research 86, 927-936
 |  Abstract »  |  Full Text »  |  PDF »

Treatment of hypoxia-induced retinopathy with targeted proapoptotic peptidomimetic in a mouse model of disease.

J. Lahdenranta, R. L. Sidman, R. Pasqualini, and W. Arap (2007)
FASEB J 21, 3272-3278
 |  Abstract »  |  Full Text »  |  PDF »

The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy.

Y. Yang, V. MacLeod, Y. Dai, Y. Khotskaya-Sample, Z. Shriver, G. Venkataraman, R. Sasisekharan, A. Naggi, G. Torri, B. Casu, et al. (2007)
Blood 110, 2041-2048
 |  Abstract »  |  Full Text »  |  PDF »

Cadherins, RhoA, and Rac1 Are Differentially Required for Stretch-Mediated Proliferation in Endothelial Versus Smooth Muscle Cells.

W. F. Liu, C. M. Nelson, J. L. Tan, and C. S. Chen (2007)
Circ. Res. 101, e44-e52
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Imaging of Cardiovascular Disease.

F. A. Jaffer, P. Libby, and R. Weissleder (2007)
Circulation 116, 1052-1061
 |  Full Text »  |  PDF »

Akt1 Signaling Regulates Integrin Activation, Matrix Recognition, and Fibronectin Assembly.

P. R. Somanath, E. S. Kandel, N. Hay, and T. V. Byzova (2007)
J. Biol. Chem. 282, 22964-22976
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of IGF-I Signaling in Retinal Endothelial Cells by Hyperglycemia.

E. C. Miller, B. E. Capps, R. R. Sanghani, D. R. Clemmons, and L. A. Maile (2007)
Invest. Ophthalmol. Vis. Sci. 48, 3878-3887
 |  Abstract »  |  Full Text »  |  PDF »

Assessment of the biological and pharmacological effects of the {alpha}{nu}{beta}3 and {alpha}{nu}{beta}5 integrin receptor antagonist, cilengitide (EMD 121974), in patients with advanced solid tumors.

S Hariharan, D Gustafson, S Holden, D McConkey, D Davis, M Morrow, M Basche, L Gore, C Zang, C. O'Bryant, et al. (2007)
Ann. Onc. 18, 1400-1407
 |  Abstract »  |  Full Text »  |  PDF »

64Cu-Labeled Tetrameric and Octameric RGD Peptides for Small-Animal PET of Tumor {alpha}v{beta}3 Integrin Expression.

Z.-b. Li, W. Cai, Q. Cao, K. Chen, Z. Wu, L. He, and X. Chen (2007)
J. Nucl. Med. 48, 1162-1171
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Inflammatory Lymphangiogenesis by Integrin {alpha}5 Blockade.

T. Dietrich, J. Onderka, F. Bock, F. E. Kruse, D. Vossmeyer, R. Stragies, G. Zahn, and C. Cursiefen (2007)
Am. J. Pathol. 171, 361-372
 |  Abstract »  |  Full Text »  |  PDF »

Necl-5/Poliovirus Receptor Interacts in cis with Integrin {alpha}Vbeta3 and Regulates Its Clustering and Focal Complex Formation.

Y. Minami, W. Ikeda, M. Kajita, T. Fujito, H. Amano, Y. Tamaru, K. Kuramitsu, Y. Sakamoto, M. Monden, and Y. Takai (2007)
J. Biol. Chem. 282, 18481-18496
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Osteopontin in Tumor Progression and Metastasis in Breast Cancer.

L. R. Rodrigues, J. A. Teixeira, F. L. Schmitt, M. Paulsson, and H. Lindmark-Mansson (2007)
Cancer Epidemiol. Biomarkers Prev. 16, 1087-1097
 |  Abstract »  |  Full Text »  |  PDF »

Nonclassic Endogenous Novel Regulators of Angiogenesis.

D. Ribatti, M. T. Conconi, and G. G. Nussdorfer (2007)
Pharmacol. Rev. 59, 185-205
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms initiating integrin-stimulated flow recruitment in arteriolar networks.

M. D. Frame, R. J. Rivers, O. Altland, and S. Cameron (2007)
J Appl Physiol 102, 2279-2287
 |  Abstract »  |  Full Text »  |  PDF »

Angiogenesis blockade as a new therapeutic approach to experimental colitis.

S. Danese, M. Sans, D. M Spencer, I. Beck, F. Donate, M. L Plunkett, C. de la Motte, R. Redline, D. E Shaw, A. D Levine, et al. (2007)
Gut 56, 855-862
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Angiogenesis and Tumor Metastasis by Targeting a Matrix Immobilized Cryptic Extracellular Matrix Epitope in Laminin.

A. Akalu, J. M. Roth, M. Caunt, D. Policarpio, L. Liebes, and P. C. Brooks (2007)
Cancer Res. 67, 4353-4363
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Cell-Organ Microenvironment Interactions in the Pathogenesis of Cancer Metastasis.

R. R. Langley and I. J. Fidler (2007)
Endocr. Rev. 28, 297-321
 |  Abstract »  |  Full Text »  |  PDF »

Phase I Evaluation of a Fully Human Anti-{alpha}v Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors.

S. A. Mullamitha, N. C. Ton, G. J.M. Parker, A. Jackson, P. J. Julyan, C. Roberts, G. A. Buonaccorsi, Y. Watson, K. Davies, S. Cheung, et al. (2007)
Clin. Cancer Res. 13, 2128-2135
 |  Abstract »  |  Full Text »  |  PDF »

Cooperation between VEGF and {beta}3 integrin during cardiac vascular development.

S. M. Weis, J. N. Lindquist, L. A. Barnes, K. M. Lutu-Fuga, J. Cui, M. R. Wood, and D. A. Cheresh (2007)
Blood 109, 1962-1970
 |  Abstract »  |  Full Text »  |  PDF »

Specific Targeting of Tumor Angiogenesis by RGD-Conjugated Ultrasmall Superparamagnetic Iron Oxide Particles Using a Clinical 1.5-T Magnetic Resonance Scanner.

C. Zhang, M. Jugold, E. C. Woenne, T. Lammers, B. Morgenstern, M. M. Mueller, H. Zentgraf, M. Bock, M. Eisenhut, W. Semmler, et al. (2007)
Cancer Res. 67, 1555-1562
 |  Abstract »  |  Full Text »  |  PDF »

Favorable Biokinetic and Tumor-Targeting Properties of 99mTc-Labeled Glucosamino RGD and Effect of Paclitaxel Therapy.

K.-H. Jung, K.-H. Lee, J.-Y. Paik, B.-H. Ko, J.-S. Bae, B. C. Lee, H. J. Sung, D. H. Kim, Y. S. Choe, and D. Y. Chi (2006)
J. Nucl. Med. 47, 2000-2007
 |  Abstract »  |  Full Text »  |  PDF »

Direct targeting of {alpha}v{beta}3 integrin on tumor cells with a monoclonal antibody, AbegrinTM.

K. Mulgrew, K. Kinneer, X.-T. Yao, B. K. Ward, M. M. Damschroder, B. Walsh, S.-Y. Mao, C. Gao, P. A. Kiener, S. Coats, et al. (2006)
Mol. Cancer Ther. 5, 3122-3129
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of {alpha}vbeta3 and {alpha}vbeta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.

S. Maubant, D. Saint-Dizier, M. Boutillon, F. Perron-Sierra, P. J. Casara, J. A. Hickman, G. C. Tucker, and E. Van Obberghen-Schilling (2006)
Blood 108, 3035-3044
 |  Abstract »  |  Full Text »  |  PDF »

Integrin signaling is critical for pathological angiogenesis.

G. H. Mahabeleshwar, W. Feng, D. R. Phillips, and T. V. Byzova (2006)
J. Exp. Med. 203, 2495-2507
 |  Abstract »  |  Full Text »  |  PDF »

In vitro and In vivo Characterization of 64Cu-Labeled AbegrinTM, a Humanized Monoclonal Antibody against Integrin {alpha}v{beta}3.

W. Cai, Y. Wu, K. Chen, Q. Cao, D. A. Tice, and X. Chen (2006)
Cancer Res. 66, 9673-9681
 |  Abstract »  |  Full Text »  |  PDF »

Magnetic resonance visualization of tumor angiogenesis by targeting neural cell adhesion molecules with the highly sensitive gadolinium-loaded apoferritin probe..

S. Geninatti Crich, B. Bussolati, L. Tei, C. Grange, G. Esposito, S. Lanzardo, G. Camussi, and S. Aime (2006)
Cancer Res. 66, 9196-9201
 |  Abstract »  |  Full Text »  |  PDF »

Cerebral Perfusion in a High-Grade Glioma Evaluated With Sonographic Contrast Pulse Sequencing Technology..

E. Vicenzini, M. C. Ricciardi, F. Puccinelli, and G. L. Lenzi (2006)
J. Ultrasound Med. 25, 1215-1218
 |  Full Text »  |  PDF »

Integrin Receptor Imaging of Breast Cancer: A Proof-of-Concept Study to Evaluate 99mTc-NC100692.

T. Bach-Gansmo, R. Danielsson, A. Saracco, B. Wilczek, T. V. Bogsrud, A. Fangberget, A. Tangerud, and D. Tobin (2006)
J. Nucl. Med. 47, 1434-1439
 |  Abstract »  |  Full Text »  |  PDF »

Fibroblast Growth Factor-2 Failed to Induce Angiogenesis in Junctional Adhesion Molecule-A-Deficient Mice.

V. G. Cooke, M. U. Naik, and U. P. Naik (2006)
Arterioscler Thromb Vasc Biol 26, 2005-2011
 |  Abstract »  |  Full Text »  |  PDF »

Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration.

B. Favier, A. Alam, P. Barron, J. Bonnin, P. Laboudie, P. Fons, M. Mandron, J.-P. Herault, G. Neufeld, P. Savi, et al. (2006)
Blood 108, 1243-1250
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Sokotrasterol Sulfate As a Novel Proangiogenic Steroid.

S. Murphy, B. Larrivee, I. Pollet, K. S. Craig, D. E. Williams, X.-H. Huang, M. Abbott, F. Wong, C. Curtis, T. P. Conrads, et al. (2006)
Circ. Res. 99, 257-265
 |  Abstract »  |  Full Text »  |  PDF »

Transduction of a Mesenchyme-specific Gene Periostin into 293T Cells Induces Cell Invasive Activity through Epithelial-Mesenchymal Transformation.

W. Yan and R. Shao (2006)
J. Biol. Chem. 281, 19700-19708
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Integrin {alpha}v{beta}3 Ameliorates Focal Cerebral Ischemic Damage in the Rat Middle Cerebral Artery Occlusion Model.

N. Shimamura, G. Matchett, H. Yatsushige, J. W. Calvert, H. Ohkuma, and J. Zhang (2006)
Stroke 37, 1902-1909
 |  Abstract »  |  Full Text »  |  PDF »

Suppression and Regression of Choroidal Neovascularization by Systemic Administration of an {alpha}5beta1 Integrin Antagonist.

N. Umeda, S. Kachi, H. Akiyama, G. Zahn, D. Vossmeyer, R. Stragies, and P. A. Campochiaro (2006)
Mol. Pharmacol. 69, 1820-1828
 |  Abstract »  |  Full Text »  |  PDF »

The Protease Complex Consisting of Dipeptidyl Peptidase IV and Seprase Plays a Role in the Migration and Invasion of Human Endothelial Cells in Collagenous Matrices..

G. Ghersi, Q. Zhao, M. Salamone, Y. Yeh, S. Zucker, and W.-T. Chen (2006)
Cancer Res. 66, 4652-4661
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Experimental Metastasis by Targeting the HUIV26 Cryptic Epitope in Collagen.

J. M. Roth, M. Caunt, A. Cretu, A. Akalu, D. Policarpio, X. Li, P. Gagne, S. Formenti, and P. C. Brooks (2006)
Am. J. Pathol. 168, 1576-1586
 |  Abstract »  |  Full Text »  |  PDF »

The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin.

Y. Huang, H. Shi, H. Zhou, X. Song, S. Yuan, and Y. Luo (2006)
Blood 107, 3564-3571
 |  Abstract »  |  Full Text »  |  PDF »

SB-267268, a Nonpeptidic Antagonist of {alpha}v{beta}3 and {alpha}v{beta}5 Integrins, Reduces Angiogenesis and VEGF Expression in a Mouse Model of Retinopathy of Prematurity..

J. L. Wilkinson-Berka, D. Jones, G. Taylor, K. Jaworski, D. J. Kelly, S. B. Ludbrook, R. N. Willette, S. Kumar, and R. E. Gilbert (2006)
Invest. Ophthalmol. Vis. Sci. 47, 1600-1605
 |  Abstract »  |  Full Text »  |  PDF »

Junctional adhesion molecule-A-induced endothelial cell migration on vitronectin is integrin {alpha}v{beta}3 specific.

M. U. Naik and U. P. Naik (2006)
J. Cell Sci. 119, 490-499
 |  Abstract »  |  Full Text »  |  PDF »

FGF-2 binding to fibrin(ogen) is required for augmented angiogenesis.

A. Sahni, A. A. Khorana, R. B. Baggs, H. Peng, and C. W. Francis (2006)
Blood 107, 126-131
 |  Abstract »  |  Full Text »  |  PDF »

Vascular Targeting of Ocular Neovascularization with a Vascular Endothelial Growth Factor121/Gelonin Chimeric Protein.

H. Akiyama, K. A. Mohamedali, R. L. e Silva, S. Kachi, J. Shen, C. Hatara, N. Umeda, S. F. Hackett, S. Aslam, M. Krause, et al. (2005)
Mol. Pharmacol. 68, 1543-1550
 |  Abstract »  |  Full Text »  |  PDF »

Biological and molecular properties of a new {alpha}v{beta}3/{alpha}v{beta}5 integrin antagonist.

L. Belvisi, T. Riccioni, M. Marcellini, L. Vesci, I. Chiarucci, D. Efrati, D. Potenza, C. Scolastico, L. Manzoni, K. Lombardo, et al. (2005)
Mol. Cancer Ther. 4, 1670-1680
 |  Abstract »  |  Full Text »  |  PDF »

Phase I Trial of a Monoclonal Antibody Specific for {alpha}v{beta}3 Integrin (MEDI-522) in Patients with Advanced Malignancies, Including an Assessment of Effect on Tumor Perfusion.

D. G. McNeel, J. Eickhoff, F. T. Lee, D. M. King, D. Alberti, J. P. Thomas, A. Friedl, J. Kolesar, R. Marnocha, J. Volkman, et al. (2005)
Clin. Cancer Res. 11, 7851-7860
 |  Abstract »  |  Full Text »  |  PDF »

microPET Imaging of Glioma Integrin {alpha}v{beta}3 Expression Using 64Cu-Labeled Tetrameric RGD Peptide.

Y. Wu, X. Zhang, Z. Xiong, Z. Cheng, D. R. Fisher, S. Liu, S. S. Gambhir, and X. Chen (2005)
J. Nucl. Med. 46, 1707-1718
 |  Abstract »  |  Full Text »  |  PDF »

Role of Angiogenesis in Cardiovascular Disease: A Critical Appraisal.

R. Khurana, M. Simons, J. F. Martin, and I. C. Zachary (2005)
Circulation 112, 1813-1824
 |  Abstract »  |  Full Text »  |  PDF »

Stable interaction between {alpha}5{beta}1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1.

I. Cascone, L. Napione, F. Maniero, G. Serini, and F. Bussolino (2005)
J. Cell Biol. 170, 993-1004
 |  Abstract »  |  Full Text »  |  PDF »

Targeting Tumor Angiogenesis: Comparison of Peptide and Polymer-Peptide Conjugates.

B. R. Line, A. Mitra, A. Nan, and H. Ghandehari (2005)
J. Nucl. Med. 46, 1552-1560
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of {alpha}v{beta}3 Integrin Survival Signaling Enhances Antiangiogenic and Antitumor Effects of Radiotherapy.

A. Abdollahi, D. W. Griggs, H. Zieher, A. Roth, K. E. Lipson, R. Saffrich, H.-J. Grone, D. E. Hallahan, R. A. Reisfeld, J. Debus, et al. (2005)
Clin. Cancer Res. 11, 6270-6279
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Tumor Growth by RGD Peptide-Directed Delivery of Truncated Tissue Factor to the Tumor Vasculature.

T. Kessler, R. Bieker, T. Padro, C. Schwoppe, T. Persigehl, C. Bremer, M. Kreuter, W. E. Berdel, and R. M. Mesters (2005)
Clin. Cancer Res. 11, 6317-6324
 |  Abstract »  |  Full Text »  |  PDF »

{alpha}v{beta}3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen.

E. Godefroy, A. Moreau-Aubry, E. Diez, B. Dreno, F. Jotereau, and Y. Guilloux (2005)
J. Exp. Med. 202, 61-72
 |  Abstract »  |  Full Text »  |  PDF »

Angiogenesis, Vasculogenesis, and Induction of Healing in Chronic Wounds.

S. M. Bauer, R. J. Bauer, and O. C. Velazquez (2005)
Vascular and Endovascular Surgery 39, 293-306
 |  Abstract »  |  PDF »

Thyroid Hormones: Rapid Reply by Surface Delivery Only.

S. Incerpi (2005)
Endocrinology 146, 2861-2863
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Expression and Function of Laminins in the Embryonic and Mature Vasculature.

R. Hallmann, N. Horn, M. Selg, O. Wendler, F. Pausch, and L. M. Sorokin (2005)
Physiol Rev 85, 979-1000
 |  Abstract »  |  Full Text »  |  PDF »

Uniform Overexpression and Rapid Accessibility of {alpha}5{beta}1 Integrin on Blood Vessels in Tumors.

P. Parsons-Wingerter, I. M. Kasman, S. Norberg, A. Magnussen, S. Zanivan, A. Rissone, P. Baluk, C. J. Favre, U. Jeffry, R. Murray, et al. (2005)
Am. J. Pathol. 167, 193-211
 |  Abstract »  |  Full Text »  |  PDF »

A Novel {alpha}v{beta}3 Integrin Antagonist Suppresses Neointima Formation for More Than 4 Weeks After Balloon Injury in Rats.

Y. Honda, T. Kitano, F. Fukuya, Y. Sato, S. Iwama, T. Morie, and M. Notake (2005)
Arterioscler Thromb Vasc Biol 25, 1376-1382
 |  Abstract »  |  Full Text »  |  PDF »

Assessment of Endogenous and Therapeutic Arteriogenesis by Contrast Ultrasound Molecular Imaging of Integrin Expression.

H. Leong-Poi, J. Christiansen, P. Heppner, C. W. Lewis, A. L. Klibanov, S. Kaul, and J. R. Lindner (2005)
Circulation 111, 3248-3254
 |  Abstract »  |  Full Text »  |  PDF »

Physiological Mechanisms of Tumor-Cell Invasion and Migration.

D. H. Geho, R. W. Bandle, T. Clair, and L. A. Liotta (2005)
Physiology 20, 194-200
 |  Abstract »  |  Full Text »  |  PDF »

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