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Science 8 April 1994:
Vol. 264. no. 5156, pp. 270 - 273
DOI: 10.1126/science.8146661
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Articles

Science, Vol 264, Issue 5156, 270-273
Copyright © 1994 by American Association for the Advancement of Science

articles

Telomere-led premeiotic chromosome movement in fission yeast

Y Chikashige, DQ Ding, H Funabiki, T Haraguchi, S Mashiko, M Yanagida, and Y Hiraoka

Kansai Advanced Research Center, Communications Research Laboratory, Kobe, Japan.

The movement of chromosomes that precedes meiosis was observed in living cells of fission yeast by fluorescence microscopy. Further analysis by in situ hybridization revealed that the telomeres remain clustered at the leading end of premeiotic chromosome movement, unlike mitotic chromosome movement in which the centromere leads. Once meiotic chromosome segregation starts, however, centromeres resume the leading position in chromosome movement, as they do in mitosis. Although the movement of the telomere first has not been observed before, the clustering of telomeres is reminiscent of the bouquet structure of meiotic-prophase chromosomes observed in higher eukaryotes, which suggests that telomeres perform specific functions required for premeiotic chromosomal events generally in eukaryotes.


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   Abstract »    Full Text »    PDF »
Role for Telomere Cap Structure in Meiosis.
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Mol. Biol. Cell 12, 3191-3203
   Abstract »    Full Text »    PDF »
Meiotic recombination and chromosome segregation in Schizosaccharomyces pombe.
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   Abstract »    Full Text »    PDF »
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   Abstract »    Full Text »
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   Abstract »    Full Text »    PDF »
Cytoplasmic microtubular system implicated in de novo formation of a Rabl-like orientation of chromosomes in fission yeast.
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   Abstract »    Full Text »    PDF »
Sequence-specific binding of Taz1p dimers to fission yeast telomeric DNA.
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   Abstract »    Full Text »    PDF »
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J. Cell Sci. 113, 4177-4191
   Abstract »    PDF »
Evidence for the coincident initiation of homolog pairing and synapsis during the telomere-clustering (bouquet) stage of meiotic prophase.
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J. Cell Sci. 113, 1033-1042
   Abstract »    PDF »
Meiotic DNA replication checkpoint control in fission yeast.
H. Murakami and P. Nurse (1999)
Genes & Dev. 13, 2581-2593
   Abstract »    Full Text »
Active-Site Mutations in the Xrn1p Exoribonuclease of Saccharomyces cerevisiae Reveal a Specific Role in Meiosis.
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Mol. Cell. Biol. 19, 5930-5942
   Abstract »    Full Text »    PDF »
Meiotic Chromosome Dynamics Dependent Upon the rec8+, rec10+ and rec11+ Genes of the Fission Yeast Schizosaccharomyces pombe.
M. D. Krawchuk, L. C. DeVeaux, and W. P. Wahls (1999)
Genetics 153, 57-68
   Abstract »    Full Text »
Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation.
G. Goshima, S. Saitoh, and M. Yanagida (1999)
Genes & Dev. 13, 1664-1677
   Abstract »    Full Text »
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A. Yamamoto, R. R. West, J. R. McIntosh, and Y. Hiraoka (1999)
J. Cell Biol. 145, 1233-1250
   Abstract »    Full Text »    PDF »
Rec8p, a Meiotic Recombination and Sister Chromatid Cohesion Phosphoprotein of the Rad21p Family Conserved from Fission Yeast to Humans.
S. Parisi, M. J. McKay, M. Molnar, M. A. Thompson, P. J. van der Spek, E. van Drunen-Schoenmaker, R. Kanaar, E. Lehmann, J. H. J. Hoeijmakers, and J. Kohli (1999)
Mol. Cell. Biol. 19, 3515-3528
   Abstract »    Full Text »    PDF »
Cell cycle dependent localization of the telomeric PARP, tankyrase, to nuclear pore complexes and centrosomes.
S Smith and T de Lange (1999)
J. Cell Sci. 112, 3649-3656
   Abstract »    PDF »
Bouquet formation in budding yeast: initiation of recombination is not required for meiotic telomere clustering.
E Trelles-Sticken, J Loidl, and H Scherthan (1999)
J. Cell Sci. 112, 651-658
   Abstract »    PDF »
Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase.
K. Furuya, K. Takahashi, and M. Yanagida (1998)
Genes & Dev. 12, 3408-3418
   Abstract »    Full Text »
Dynamics of Centromeres during Metaphase-Anaphase Transition in Fission Yeast: Dis1 Is Implicated in Force Balance in Metaphase Bipolar Spindle.
K. Nabeshima, T. Nakagawa, A. F. Straight, A. Murray, Y. Chikashige, Y. M. Yamashita, Y. Hiraoka, and M. Yanagida (1998)
Mol. Biol. Cell 9, 3211-3225
   Abstract »    Full Text »
Two Modes of Survival of Fission Yeast Without Telomerase.
T. M. Nakamura, J. P. Cooper, and T. R. Cech (1998)
Science 282, 493-496
   Abstract »    Full Text »
The Role of Topoisomerase II in Meiotic Chromosome Condensation and Segregation in Schizosaccharomyces pombe.
E. Hartsuiker, J. Bähler, and J. Kohli (1998)
Mol. Biol. Cell 9, 2739-2750
   Abstract »    Full Text »
cut11+: A Gene Required for Cell Cycle-dependent Spindle Pole Body Anchoring in the Nuclear Envelope and Bipolar Spindle Formation in Schizosaccharomyces pombe.
R. R. West, E. V. Vaisberg, R. Ding, P. Nurse, and J. R. McIntosh (1998)
Mol. Biol. Cell 9, 2839-2855
   Abstract »    Full Text »
Telomere-mediated chromosome pairing during meiosis in budding yeast.
B. Rockmill and G. S. Roeder (1998)
Genes & Dev. 12, 2574-2586
   Abstract »    Full Text »
FH3, A Domain Found in Formins, Targets the Fission Yeast Formin Fus1 to the Projection Tip During Conjugation.
J. Petersen, O. Nielsen, R. Egel, and I. M. Hagan (1998)
J. Cell Biol. 141, 1217-1228
   Abstract »    Full Text »    PDF »
Homologous Chromosome Pairing in Drosophila melanogaster Proceeds through Multiple Independent Initiations.
J. C. Fung, W. F. Marshall, A. Dernburg, D. A. Agard, and J. W. Sedat (1998)
J. Cell Biol. 141, 5-20
   Abstract »    Full Text »    PDF »
A Novel Fission Yeast Gene, tht1+, Is Required for the Fusion of Nuclear Envelopes during Karyogamy.
Y. Tange, T. Horio, M. Shimanuki, D.-Q. Ding, Y. Hiraoka, and O. Niwa (1998)
J. Cell Biol. 140, 247-258
   Abstract »    Full Text »    PDF »
Aspects of three-dimensional chromosome reorganization during the onset of human male meiotic prophase.
H Scherthan, R Eils, E Trelles-Sticken, S Dietzel, T Cremer, H Walt, and A Jauch (1998)
J. Cell Sci. 111, 2337-2351
   Abstract »    PDF »
The fission yeast microtubule cytoskeleton.
I. Hagan (1998)
J. Cell Sci. 111, 1603-1612
   Abstract »    PDF »
F-actin distribution and function during sexual differentiation in Schizosaccharomyces pombe.
J Petersen, O Nielsen, R Egel, and I. Hagan (1998)
J. Cell Sci. 111, 867-876
   Abstract »    PDF »
Oscillatory nuclear movement in fission yeast meiotic prophase is driven by astral microtubules, as revealed by continuous observation of chromosomes and microtubules in living cells.
D. Ding, Y Chikashige, T Haraguchi, and Y Hiraoka (1998)
J. Cell Sci. 111, 701-712
   Abstract »    PDF »
Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis.
M. Shen, C. Haggblom, M. Vogt, T. Hunter, and K. P. Lu (1997)
PNAS 94, 13618-13623
   Abstract »    Full Text »    PDF »
Functionally interacting telomerase RNAs in the yeast telomerase complex.
J. Prescott and E. H. Blackburn (1997)
Genes & Dev. 11, 2790-2800
   Abstract »    Full Text »    PDF »
Meiotic chromosomes: it takes two to tango.
G. S. Roeder (1997)
Genes & Dev. 11, 2600-2621
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Telomeres Cluster De Novo before the Initiation of Synapsis: A Three-dimensional Spatial Analysis of Telomere Positions before and during Meiotic Prophase.
H. W. Bass, W. F. Marshall, J. W. Sedat, D. A. Agard, and W. Z. Cande (1997)
J. Cell Biol. 137, 5-18
   Abstract »    Full Text »    PDF »
The meiotic recombination hot spot created by the single-base substitution ade6-M26 results in remodeling of chromatin structure in fission yeast..
K Mizuno, Y Emura, M Baur, J Kohli, K Ohta, and T Shibata (1997)
Genes & Dev. 11, 876-886
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Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro..
J Prescott and E H Blackburn (1997)
Genes & Dev. 11, 528-540
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Evidence for cell cycle-specific, spindle pole body-mediated, nuclear positioning in the fission yeast Schizosaccharomyces pombe.
I Hagan and M Yanagida (1997)
J. Cell Sci. 110, 1851-1866
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The transcriptional basis of chromosome pairing.
P. Cook (1997)
J. Cell Sci. 110, 1033-1040
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Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function.
K Ekwall, E. Nimmo, J. Javerzat, B Borgstrom, R Egel, G Cranston, and R Allshire (1996)
J. Cell Sci. 109, 2637-2648
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An unusual sequence arrangement in the telomeres of the germ-line micronucleus in Tetrahymena thermophila..
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Aging mechanisms.
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