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Science 25 March 1994:
Vol. 263. no. 5154, pp. 1715 - 1720
DOI: 10.1126/science.8134835
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Articles

Science, Vol 263, Issue 5154, 1715-1720
Copyright © 1994 by American Association for the Advancement of Science

articles

New challenges in biomaterials

NA Peppas and R Langer

School of Chemical Engineering, Purdue University, West Lafayette, IN 47907-1283.

Significant opportunities and challenges exist in the creation and characterization of biomaterials. Materials have been designed for contact with blood, as replacements for soft and hard tissues, as adhesives, and as dental materials. Current methods of synthesis and characterization of these materials are outlined. Approaches for controlling the interface between tissue and biomaterials and ways in which the engineered materials may contribute to medicine are considered.


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Evidence of Chemical Bonding at Biomaterial-Hard Tissue Interfaces.
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Photolithographic Synthesis of Intelligent Microgels.
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Soft Tissue and Epithelial Models.
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Advances in Dental Research 13, 57-66
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Reversible Hydrogels from Self-Assembling Artificial Proteins.
W. A. Petka, J. L. Harden, K. P. McGrath, D. Wirtz, and D. A. Tirrell (1998)
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Measurements of attractive forces between proteins and end-grafted poly(ethylene glycol) chains.
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Monitoring Degradation by Controlled Cooling of Absorbing Polymers.
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