Science 25 February 1994: Vol. 263. no. 5150, pp. 1153 - 1156 DOI: 10.1126/science.8108735

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Articles

Chromatin Disassembly from the PHO5 Promoter Is Essential for the Recruitment of the General Transcription Machinery and Coactivators.

M. W. Adkins, S. K. Williams, J. Linger, and J. K. Tyler (2007)
Mol. Cell. Biol. 27, 6372-6382
 |  Abstract »  |  Full Text »  |  PDF »

Constitutive Expression of Functionally Active Cyclin-Dependent Kinases and Their Binding Partners Suggests Noncanonical Functions of Cell Cycle Regulators in Differentiated Neurons.

S. Schmetsdorf, U. Gartner, and T. Arendt (2007)
Cereb Cortex 17, 1821-1829
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of a Cyclin-CDK-CDK Inhibitor Complex by Inositol Pyrophosphates.

Y.-S. Lee, S. Mulugu, J. D. York, and E. K. O'Shea (2007)
Science 316, 109-112
 |  Abstract »  |  Full Text »  |  PDF »

Nucleocytoplasmic Shuttling of the Retinoblastoma Tumor Suppressor Protein via Cdk Phosphorylation-dependent Nuclear Export.

W. Jiao, J. Datta, H.-M. Lin, M. Dundr, and S. G. Rane (2006)
J. Biol. Chem. 281, 38098-38108
 |  Abstract »  |  Full Text »  |  PDF »

A Quantitative Results-driven Approach to Analyzing Multisite Protein Phosphorylation: The Phosphate-dependent Phosphorylation Profile of the Transcription Factor Pho4.

F. Zappacosta, T. S. Collingwood, M. J. Huddleston, and R. S. Annan (2006)
Mol. Cell. Proteomics 5, 2019-2030
 |  Abstract »  |  Full Text »  |  PDF »

DNA bending by bHLH charge variants.

R. J. McDonald, J. D. Kahn, and L. J. Maher III (2006)
Nucleic Acids Res. 34, 4846-4856
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of the Oxidative Stress Response Through Slt2p-Dependent Destruction of Cyclin C in Saccharomyces cerevisiae.

E. Krasley, K. F. Cooper, M. J. Mallory, R. Dunbrack, and R. Strich (2006)
Genetics 172, 1477-1486
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Combining chemical genetics and proteomics to identify protein kinase substrates.

N. Dephoure, R. W. Howson, J. D. Blethrow, K. M. Shokat, and E. K. O'Shea (2005)
PNAS 102, 17940-17945
 |  Abstract »  |  Full Text »  |  PDF »

Direct Labeling of Polyphosphate at the Ultrastructural Level in Saccharomyces cerevisiae by Using the Affinity of the Polyphosphate Binding Domain of Escherichia coli Exopolyphosphatase.

K. Saito, R. Ohtomo, Y. Kuga-Uetake, T. Aono, and M. Saito (2005)
Appl. Envir. Microbiol. 71, 5692-5701
 |  Abstract »  |  Full Text »  |  PDF »

An intracellular phosphate buffer filters transient fluctuations in extracellular phosphate levels.

M. R. Thomas and E. K. O'Shea (2005)
PNAS 102, 9565-9570
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Plc1p, Arg82p, and Kcs1p, Enzymes Involved in Inositol Pyrophosphate Synthesis, Are Essential for Phosphate Regulation and Polyphosphate Accumulation in Saccharomyces cerevisiae.

C. Auesukaree, H. Tochio, M. Shirakawa, Y. Kaneko, and S. Harashima (2005)
J. Biol. Chem. 280, 25127-25133
 |  Abstract »  |  Full Text »  |  PDF »

A Systematic High-Throughput Screen of a Yeast Deletion Collection for Mutants Defective in PHO5 Regulation.

S. Huang and E. K. O'Shea (2005)
Genetics 169, 1859-1871
 |  Abstract »  |  Full Text »  |  PDF »

Genomic Analysis of PIS1 Gene Expression.

M. E. Gardocki, M. Bakewell, D. Kamath, K. Robinson, K. Borovicka, and J. M. Lopes (2005)
Eukaryot. Cell 4, 604-614
 |  Abstract »  |  Full Text »  |  PDF »

Coevolution of Cyclin Pcl5 and Its Substrate Gcn4.

T. Gildor, R. Shemer, A. Atir-Lande, and D. Kornitzer (2005)
Eukaryot. Cell 4, 310-318
 |  Abstract »  |  Full Text »  |  PDF »

Inaugural Article: Biography of Erin K. O'Shea.

M. Marino (2004)
PNAS 101, 14312-14314
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Low Affinity Orthophosphate Carriers Regulate PHO Gene Expression Independently of Internal Orthophosphate Concentration in Saccharomyces cerevisiae.

B. Pinson, M. Merle, J.-M. Franconi, and B. Daignan-Fornier (2004)
J. Biol. Chem. 279, 35273-35280
 |  Abstract »  |  Full Text »  |  PDF »

The Trypanosoma brucei Cyclin, CYC2, Is Required for Cell Cycle Progression through G1 Phase and for Maintenance of Procyclic Form Cell Morphology.

T. C. Hammarton, M. Engstler, and J. C. Mottram (2004)
J. Biol. Chem. 279, 24757-24764
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Phosphate Serves as a Signal for the Regulation of the PHO Pathway in Saccharomyces cerevisiae.

C. Auesukaree, T. Homma, H. Tochio, M. Shirakawa, Y. Kaneko, and S. Harashima (2004)
J. Biol. Chem. 279, 17289-17294
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative Analysis of GAL Genetic Switch of Saccharomyces cerevisiae Reveals That Nucleocytoplasmic Shuttling of Gal80p Results in a Highly Sensitive Response to Galactose.

M. Verma, P. J. Bhat, and K. V. Venkatesh (2003)
J. Biol. Chem. 278, 48764-48769
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Chromatin Remodeling by Inositol Polyphosphates.

D. J. Steger, E. S. Haswell, A. L. Miller, S. R. Wente, and E. K. O'Shea (2003)
Science 299, 114-116
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorus Effects on Metabolic Processes in Monoxenic Arbuscular Mycorrhiza Cultures.

P. A. Olsson, I. M. van Aarle, W. G. Allaway, A. E. Ashford, and H. Rouhier (2002)
Plant Physiology 130, 1162-1171
 |  Abstract »  |  Full Text »  |  PDF »

Reconstitution of Nucleosome Positioning, Remodeling, Histone Acetylation, and Transcriptional Activation on the PHO5 Promoter.

A. R. Terrell, S. Wongwisansri, J. L. Pilon, and P. J. Laybourn (2002)
J. Biol. Chem. 277, 31038-31047
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of the Transcription Factor Gcn4 by Pho85 Cyclin Pcl5.

R. Shemer, A. Meimoun, T. Holtzman, and D. Kornitzer (2002)
Mol. Cell. Biol. 22, 5395-5404
 |  Abstract »  |  Full Text »  |  PDF »

Dissection of a Complex Phenotype by Functional Genomics Reveals Roles for the Yeast Cyclin-Dependent Protein Kinase Pho85 in Stress Adaptation and Cell Integrity.

D. Huang, J. Moffat, and B. Andrews (2002)
Mol. Cell. Biol. 22, 5076-5088
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Regulatory Roles of a Novel Saccharomyces cerevisiae Protein, Encoded by YOL002c, in Lipid and Phosphate Metabolism.

I. V. Karpichev, L. Cornivelli, and G. M. Small (2002)
J. Biol. Chem. 277, 19609-19617
 |  Abstract »  |  Full Text »  |  PDF »

Novel Fission Yeast Cdc7-Dbf4-Like Kinase Complex Required for the Initiation and Progression of Meiotic Second Division.

T. Nakamura, M. Nakamura-Kubo, T. Nakamura, and C. Shimoda (2002)
Mol. Cell. Biol. 22, 309-320
 |  Abstract »  |  Full Text »  |  PDF »

Phosphate Transport and Sensing in Saccharomyces cerevisiae.

D. D. Wykoff and E. K. O'Shea (2001)
Genetics 159, 1491-1499
 |  Abstract »  |  Full Text »  |  PDF »

Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response.

A. S. Carroll, A. C. Bishop, J. L. DeRisi, K. M. Shokat, and E. K. O'Shea (2001)
PNAS 98, 12578-12583
 |  Abstract »  |  Full Text »  |  PDF »

Functional Analysis of the Cyclin-Dependent Kinase Inhibitor Pho81 Identifies a Novel Inhibitory Domain.

S. Huang, D. A. Jeffery, M. D. Anthony, and E. K. O'Shea (2001)
Mol. Cell. Biol. 21, 6695-6705
 |  Abstract »  |  Full Text »  |  PDF »

Antagonistic Controls of Autophagy and Glycogen Accumulation by Snf1p, the Yeast Homolog of AMP-Activated Protein Kinase, and the Cyclin-Dependent Kinase Pho85p.

Z. Wang, W. A. Wilson, M. A. Fujino, and P. J. Roach (2001)
Mol. Cell. Biol. 21, 5742-5752
 |  Abstract »  |  Full Text »  |  PDF »

A Pcl-Like Cyclin of Aspergillus nidulans Is Transcriptionally Activated by Developmental Regulators and Is Involved in Sporulation.

N. Schier, R. Liese, and R. Fischer (2001)
Mol. Cell. Biol. 21, 4075-4088
 |  Abstract »  |  Full Text »

Regulation of Fumonisin B1 Biosynthesis and Conidiation in Fusarium verticillioides by a Cyclin-Like (C-Type) Gene, FCC1.

W.-B. Shim and C. P. Woloshuk (2001)
Appl. Envir. Microbiol. 67, 1607-1612
 |  Abstract »  |  Full Text »

BUR1 and BUR2 Encode a Divergent Cyclin-Dependent Kinase-Cyclin Complex Important for Transcription In Vivo.

S. Yao, A. Neiman, and G. Prelich (2000)
Mol. Cell. Biol. 20, 7080-7087
 |  Abstract »  |  Full Text »

A Pcl-like Cyclin Activates the Res2p-Cdc10p Cell Cycle "Start" Transcriptional Factor Complex in Fission Yeast.

K. Tanaka and H. Okayama (2000)
Mol. Biol. Cell 11, 2845-2862
 |  Abstract »  |  Full Text »

Mitochondria-to-Nuclear Signaling Is Regulated by the Subcellular Localization of the Transcription Factors Rtg1p and Rtg3p.

T. Sekito, J. Thornton, and R. A. Butow (2000)
Mol. Biol. Cell 11, 2103-2115
 |  Abstract »  |  Full Text »

SURVEY AND SUMMARY: Saccharomyces cerevisiae basic helix-loop-helix proteins regulate diverse biological processes.

K. A. Robinson and J. M. Lopes (2000)
Nucleic Acids Res. 28, 1499-1505
 |  Abstract »  |  Full Text »  |  PDF »

Isolation of Trypanosoma brucei CYC2 and CYC3 Cyclin Genes by Rescue of a Yeast G1 Cyclin Mutant. FUNCTIONAL CHARACTERIZATION OF CYC2.

J. J. Van Hellemond, P. Neuville, R. T. Schwarz, K. R. Matthews, and J. C. Mottram (2000)
J. Biol. Chem. 275, 8315-8323
 |  Abstract »  |  Full Text »  |  PDF »

Degradation of the Transcription Factor Gcn4 Requires the Kinase Pho85 and the SCFCDC4 Ubiquitin-Ligase Complex.

A. Meimoun, T. Holtzman, Z. Weissman, H. J. McBride, D. J. Stillman, G. R. Fink, and D. Kornitzer (2000)
Mol. Biol. Cell 11, 915-927
 |  Abstract »  |  Full Text »

Mammalian Cdk5 is a functional homologue of the budding yeast Pho85 cyclin-dependent protein kinase.

D. Huang, G. Patrick, J. Moffat, L.-H. Tsai, and B. Andrews (1999)
PNAS 96, 14445-14450
 |  Abstract »  |  Full Text »  |  PDF »

Mouse Cyclin-dependent Kinase (Cdk) 5 Is a Functional Homologue of a Yeast Cdk, Pho85 Kinase.

M. Nishizawa, Y. Kanaya, and A. Toh-e (1999)
J. Biol. Chem. 274, 33859-33862
 |  Abstract »  |  Full Text »  |  PDF »

The Saccharomyces cerevisiae RanGTP-Binding Protein Msn5p Is Involved in Different Signal Transduction Pathways.

P. M. Alepuz, D. Matheos, K. W. Cunningham, and F. Estruch (1999)
Genetics 153, 1219-1231
 |  Abstract »  |  Full Text »

Substrate Targeting of the Yeast Cyclin-Dependent Kinase Pho85p by the Cyclin Pcl10p.

W. A. Wilson, A. M. Mahrenholz, and P. J. Roach (1999)
Mol. Cell. Biol. 19, 7020-7030
 |  Abstract »  |  Full Text »  |  PDF »

An Arabidopsis Cell Cycle -Dependent Kinase-Related Gene, CDC2b, Plays a Role in Regulating Seedling Growth in Darkness.

T. Yoshizumi, N. Nagata, H. Shimada, and M. Matsui (1999)
PLANT CELL 11, 1883-1896
 |  Abstract »  |  Full Text »

An In Vitro System Recapitulates Chromatin Remodeling at the PHO5 Promoter.

E. S. Haswell and E. K. O'Shea (1999)
Mol. Cell. Biol. 19, 2817-2827
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Cdc28 Cyclin-Dependent Protein Kinase Activity during the Cell Cycle of the Yeast Saccharomyces cerevisiae.

M. D. Mendenhall and A. E. Hodge (1998)
Microbiol. Mol. Biol. Rev. 62, 1191-1243
 |  Abstract »  |  Full Text »  |  PDF »

A Genetic Study of Signaling Processes for Repression of PHO5 Transcription in Saccharomyces cerevisiae.

W.-T. W. Lau, K. R. Schneider, and E. K. O'Shea (1998)
Genetics 150, 1349-1359
 |  Abstract »  |  Full Text »

Requirements for Chromatin Modulation and Transcription Activation by the Pho4 Acidic Activation Domain.

P. C. McAndrew, J. Svaren, S. R. Martin, W. Hörz, and C. R. Goding (1998)
Mol. Cell. Biol. 18, 5818-5827
 |  Abstract »  |  Full Text »

Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121.

A. Kaffman, N. M. Rank, and E. K. O'Shea (1998)
Genes & Dev. 12, 2673-2683
 |  Abstract »  |  Full Text »

Phosphorylation of Sic1, a Cyclin-dependent Kinase (Cdk) Inhibitor, by Cdk Including Pho85 Kinase Is Required for Its Prompt Degradation.

M. Nishizawa, M. Kawasumi, M. Fujino, and A. Toh-e (1998)
Mol. Biol. Cell 9, 2393-2405
 |  Abstract »  |  Full Text »

Cyclin Partners Determine Pho85 Protein Kinase Substrate Specificity In Vitro and In Vivo: Control of Glycogen Biosynthesis by Pcl8 and Pcl10.

D. Huang, J. Moffat, W. A. Wilson, L. Moore, C. Cheng, P. J. Roach, and B. Andrews (1998)
Mol. Cell. Biol. 18, 3289-3299
 |  Abstract »  |  Full Text »

Cooperative Pho2-Pho4 Interactions at the PHO5 Promoter Are Critical for Binding of Pho4 to UASp1 and for Efficient Transactivation by Pho4 at UASp2.

S. Barbaric, M. Münsterkötter, C. Goding, and W. Hörz (1998)
Mol. Cell. Biol. 18, 2629-2639
 |  Abstract »  |  Full Text »

Physiological Regulation of the Derepressible Phosphate Transporter in Saccharomyces cerevisiae.

P. Martinez, R. Zvyagilskaya, P. Allard, and B. L. Persson (1998)
J. Bacteriol. 180, 2253-2256
 |  Abstract »  |  Full Text »

Swi5 Controls a Novel Wave of Cyclin Synthesis in Late Mitosis.

B. L. Aerne, A. L. Johnson, J. H. Toyn, and L. H. Johnston (1998)
Mol. Biol. Cell 9, 945-956
 |  Abstract »  |  Full Text »

An Essential Function of a Phosphoinositide-Specific Phospholipase C Is Relieved by Inhibition of a Cyclin-Dependent Protein Kinase in the Yeast Saccharomyces cerevisiae.

(1998)
Genetics 148, 33-48

Nucleosome Transactions on the Promoters of the Yeast GAL and PHO Genes.

D. Lohr (1997)
J. Biol. Chem. 272, 26795-26798
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Cyclin G2 Is Up-regulated during Growth Inhibition and B Cell Antigen Receptor-mediated Cell Cycle Arrest.

M. C. Horne, K. L. Donaldson, G. L. Goolsby, D. Tran, M. Mulheisen, J. W. Hell, and A. F. Wahl (1997)
J. Biol. Chem. 272, 12650-12661
 |  Abstract »  |  Full Text »  |  PDF »

Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae..

I B Castano, P M Brzoska, B U Sadoff, H Chen, and M F Christman (1996)
Genes & Dev. 10, 2564-2576
 |  Abstract »  |  PDF »

Cyclin G1 and Cyclin G2 Comprise a New Family of Cyclins with Contrasting Tissue-specific and Cell Cycle-regulated Expression.

M. C. Horne, G. L. Goolsby, K. L. Donaldson, D. Tran, M. Neubauer, and A. F. Wahl (1996)
J. Biol. Chem. 271, 6050-6061
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitors of mammalian G1 cyclin-dependent kinases..

C J Sherr and J M Roberts (1995)
Genes & Dev. 9, 1149-1163
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Cell cycle control by a complex of the cyclin HCS26 (PCL1) and the kinase PHO85.

F. Espinoza, J Ogas, I Herskowitz, and D. Morgan (1994)
Science 266, 1388-1391
 |  Abstract »  |  PDF »

The PCL2 (ORFD)-PHO85 cyclin-dependent kinase complex: a cell cycle regulator in yeast.

V Measday, L Moore, J Ogas, M Tyers, and B Andrews (1994)
Science 266, 1391-1395
 |  Abstract »  |  PDF »

Phosphate-regulated inactivation of the kinase PHO80-PHO85 by the CDK inhibitor PHO81.

K. Schneider, R. Smith, and E. O'Shea (1994)
Science 266, 122-126
 |  Abstract »  |  PDF »

Differential regulation of E2F transactivation by cyclin/cdk2 complexes..

B D Dynlacht, O Flores, J A Lees, and E Harlow (1994)
Genes & Dev. 8, 1772-1786
 |  Abstract »  |  PDF »

Researchers find new role for cell cycle proteins.

J Marx (1994)
Science 263, 1093
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Transcriptional Regulation of the Yeast PHO8 Promoter in Comparison to the Coregulated PHO5 Promoter.

M. Munsterkotter, S. Barbaric, and W. Horz (2000)
J. Biol. Chem. 275, 22678-22685
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of the Yeast Transcriptional Factor PHO2 Activity by Phosphorylation.

C. Liu, Z. Yang, J. Yang, Z. Xia, and S. Ao (2000)
J. Biol. Chem. 275, 31972-31978
 |  Abstract »  |  Full Text »  |  PDF »

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