Science 25 February 1994: Vol. 263. no. 5150, pp. 1139 - 1143 DOI: 10.1126/science.7509084

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Articles

Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells.

L. Gabrysova, K. S. Nicolson, H. B. Streeter, J. Verhagen, C. A. Sabatos-Peyton, D. J. Morgan, and D. C. Wraith (2009)
J. Exp. Med. 206, 1755-1767
 |  Abstract »  |  Full Text »  |  PDF »

Autoantigen Immunization at Different Sites Reveals a Role for Anti-Inflammatory Effects of IFN-{gamma} in Regulating Susceptibility to Experimental Autoimmune Encephalomyelitis.

S. Pastor, A. Minguela, W. Mi, and E. S. Ward (2009)
J. Immunol. 182, 5268-5275
 |  Abstract »  |  Full Text »  |  PDF »

Targeting of Myelin Protein Zero in a Spontaneous Autoimmune Polyneuropathy.

H.-J. Kim, C.-G. Jung, M. A. Jensen, D. Dukala, and B. Soliven (2008)
J. Immunol. 181, 8753-8760
 |  Abstract »  |  Full Text »  |  PDF »

TCR Down-Regulation Controls Virus-Specific CD8+ T Cell Responses.

C. M. Bonefeld, M. Haks, B. Nielsen, M. von Essen, L. Boding, A. K. Hansen, J. M. Larsen, N. Odum, P. Krimpenfort, A. Kruisbeek, et al. (2008)
J. Immunol. 181, 7786-7799
 |  Abstract »  |  Full Text »  |  PDF »

Antigen-Driven Interactions with Dendritic Cells and Expansion of Foxp3+ Regulatory T Cells Occur in the Absence of Inflammatory Signals.

P. Chappert, M. Leboeuf, P. Rameau, D. Stockholm, R. Liblau, O. Danos, J. M. Davoust, and D.-A. Gross (2008)
J. Immunol. 180, 327-334
 |  Abstract »  |  Full Text »  |  PDF »

Sex-Defined T-Cell Responses to Cardiac Self Determine Differential Outcomes of Murine Dilated Cardiomyopathy.

D. Jane-wit, C. Z. Altuntas, J. Monti, J. M. Johnson, T. G. Forsthuber, and V. K. Tuohy (2008)
Am. J. Pathol. 172, 11-21
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Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis.

F. Odoardi, N. Kawakami, Z. Li, C. Cordiglieri, K. Streyl, M. Nosov, W. E. F. Klinkert, J. W. Ellwart, J. Bauer, H. Lassmann, et al. (2007)
PNAS 104, 920-925
 |  Abstract »  |  Full Text »  |  PDF »

Feedback Regulation of Murine Autoimmunity via Dominant Anti-Inflammatory Effects of Interferon {gamma}.

A. Minguela, S. Pastor, W. Mi, J. A. Richardson, and E. S. Ward (2007)
J. Immunol. 178, 134-144
 |  Abstract »  |  Full Text »  |  PDF »

Loss of the Surface Antigen 3G11 Characterizes a Distinct Population of Anergic/Regulatory T Cells in Experimental Autoimmune Encephalomyelitis.

G.-X. Zhang, S. Yu, D. Calida, Z. Zhao, B. Gran, M. Kamoun, and A. Rostami (2006)
J. Immunol. 176, 3366-3373
 |  Abstract »  |  Full Text »  |  PDF »

Antigen dose governs the shaping of CTL repertoires in vitro and in vivo.

M. Kim, H.-B. Moon, K. Kim, and K.-Y. Lee (2006)
Int. Immunol. 18, 435-444
 |  Abstract »  |  Full Text »  |  PDF »

The ICOS Molecule Plays a Crucial Role in the Development of Mucosal Tolerance.

K. Miyamoto, C. I. Kingsley, X. Zhang, C. Jabs, L. Izikson, R. A. Sobel, H. L. Weiner, V. K. Kuchroo, and A. H. Sharpe (2005)
J. Immunol. 175, 7341-7347
 |  Abstract »  |  Full Text »  |  PDF »

Immunomodulatory potential of heteroclitic analogs of the dominant T-cell epitope of lipocalin allergen Bos d 2 on specific T cells.

T. Kinnunen, W. W. Kwok, A. Narvanen, M. Rytkonen-Nissinen, A. Immonen, S. Saarelainen, A. Taivainen, and T. Virtanen (2005)
Int. Immunol. 17, 1573-1581
 |  Abstract »  |  Full Text »  |  PDF »

Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis.

C. E. Smith, T. N. Eagar, J. L. Strominger, and S. D. Miller (2005)
PNAS 102, 9595-9600
 |  Abstract »  |  Full Text »  |  PDF »

T Cells in G1 Provide a Memory-Like Response to Secondary Stimulation.

I. Munitic, P. E. Ryan, and J. D. Ashwell (2005)
J. Immunol. 174, 4010-4018
 |  Abstract »  |  Full Text »  |  PDF »

Changes to peptide structure, not concentration, contribute to expansion of the lowest avidity cytotoxic T lymphocytes.

G. R. Leggatt, S. Narayan, G. J. P. Fernando, and I. H. Frazer (2004)
J. Leukoc. Biol. 76, 787-795
 |  Abstract »  |  Full Text »  |  PDF »

Cathepsin-Dependent Apoptosis Triggered by Supraoptimal Activation of T Lymphocytes: A Possible Mechanism of High Dose Tolerance.

M.-C. Michallet, F. Saltel, M. Flacher, J.-P. Revillard, and L. Genestier (2004)
J. Immunol. 172, 5405-5414
 |  Abstract »  |  Full Text »  |  PDF »

The Activation Status of Neuroantigen-specific T Cells in the Target Organ Determines the Clinical Outcome of Autoimmune Encephalomyelitis.

N. Kawakami, S. Lassmann, Z. Li, F. Odoardi, T. Ritter, T. Ziemssen, W. E.F. Klinkert, J. W. Ellwart, M. Bradl, K. Krivacic, et al. (2004)
J. Exp. Med. 199, 185-197
 |  Abstract »  |  Full Text »  |  PDF »

Chronic Exposure to Low Levels of Antigen in the Periphery Causes Reversible Functional Impairment Correlating with Changes in CD5 Levels in Monoclonal CD8 T Cells.

P. Stamou, J. de Jersey, D. Carmignac, C. Mamalaki, D. Kioussis, and B. Stockinger (2003)
J. Immunol. 171, 1278-1284
 |  Abstract »  |  Full Text »  |  PDF »

IL-1 Receptor-Associated Kinase 1 Regulates Susceptibility to Organ-Specific Autoimmunity.

C. Deng, C. Radu, A. Diab, M. F. Tsen, R. Hussain, J. S. Cowdery, M. K. Racke, and J. A. Thomas (2003)
J. Immunol. 170, 2833-2842
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory T Cells Control Autoimmunity In Vivo by Inducing Apoptotic Depletion of Activated Pathogenic Lymphocytes.

L. T. Madakamutil, I. Maricic, E. Sercarz, and V. Kumar (2003)
J. Immunol. 170, 2985-2992
 |  Abstract »  |  Full Text »  |  PDF »

CD28 Signal Enhances Apoptosis of CD8 T Cells After Strong TCR Ligation.

X.-Z. Yu, P. J. Martin, and C. Anasetti (2003)
J. Immunol. 170, 3002-3006
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Regulation as a Side Effect of Homeostasis and Competition.

T. Barthlott, G. Kassiotis, and B. Stockinger (2003)
J. Exp. Med. 197, 451-460
 |  Abstract »  |  Full Text »  |  PDF »

Effector CD4 Cells Are Tolerized Upon Exposure to Parenchymal Self-Antigen.

A. D. Higgins, M. A. Mihalyo, and A. J. Adler (2002)
J. Immunol. 169, 3622-3629
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Expression of the Tyrosine Phosphatase Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 Determines T Cell Activation Threshold and Severity of Experimental Autoimmune Encephalomyelitis.

C. Deng, A. Minguela, R. Z. Hussain, A. E. Lovett-Racke, C. Radu, E. S. Ward, and M. K. Racke (2002)
J. Immunol. 168, 4511-4518
 |  Abstract »  |  Full Text »  |  PDF »

Antigen challenge leads to in vivo activation and elimination of highly polarized TH1 memory T cells.

N. Hayashi, D. Liu, B. Min, S. Z. Ben-Sasson, and W. E. Paul (2002)
PNAS 99, 6187-6191
 |  Abstract »  |  Full Text »  |  PDF »

The Role of IL-12 in the Induction of Intravenous Tolerance in Experimental Autoimmune Encephalomyelitis.

G.-X. Zhang, H. Xu, M. Kishi, D. Calida, and A. Rostami (2002)
J. Immunol. 168, 2501-2507
 |  Abstract »  |  Full Text »  |  PDF »

Influence of Parasite Load on the Ability of Type 1 T Cells To Control Leishmania major Infection.

B. Hondowicz and P. Scott (2002)
Infect. Immun. 70, 498-503
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Induction of tolerance in autoimmune diseases by hematopoietic stem cell transplantation: getting closer to a cure?.

R. K. Burt, S. Slavin, W. H. Burns, and A. M. Marmont (2002)
Blood 99, 768-784
 |  Abstract »  |  Full Text »  |  PDF »

Vaccination, prevention, and treatment of experimental autoimmune neuritis (EAN) by an oligomerized T cell epitope.

M. Stienekemeier, K. Falk, O. Rotzschke, A. Weishaupt, C. Schneider, K. V. Toyka, R. Gold, and J. L. Strominger (2001)
PNAS 98, 13872-13877
 |  Abstract »  |  Full Text »  |  PDF »

Possible Role of Organ-Specific Autoantigen for Fas Ligand-Mediated Activation-Induced Cell Death in Murine Sjogren's Syndrome.

N. Ishimaru, K. Yanagi, K. Ogawa, T. Suda, I. Saito, and Y. Hayashi (2001)
J. Immunol. 167, 6031-6037
 |  Abstract »  |  Full Text »  |  PDF »

A Closer Look at Homeostatic Proliferation of CD4+ T Cells: Costimulatory Requirements and Role in Memory Formation.

H. Gudmundsdottir and L. A. Turka (2001)
J. Immunol. 167, 3699-3707
 |  Abstract »  |  Full Text »  |  PDF »

Anergy in Peripheral Memory Cd4+ T Cells Induced by Low Avidity Engagement of T Cell Receptor.

S. Mirshahidi, C.-T. Huang, and S. Sadegh-Nasseri (2001)
J. Exp. Med. 194, 719-732
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Anti-CD3{{epsilon}} F(ab')2 Prevents Graft-Versus-Host Disease by Selectively Depleting Donor T Cells Activated by Recipient Alloantigens.

X.-Z. Yu, S. J. Bidwell, P. J. Martin, and C. Anasetti (2001)
J. Immunol. 166, 5835-5839
 |  Abstract »  |  Full Text »  |  PDF »

Anergy Induction by Dimeric TCR Ligands.

H. Appel, N. P. Seth, L. Gauthier, and K. W. Wucherpfennig (2001)
J. Immunol. 166, 5279-5285
 |  Abstract »  |  Full Text »  |  PDF »

Tolerance and Autoimmunity.

T. Kamradt and N. A. Mitchison (2001)
N. Engl. J. Med. 344, 655-664
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Fas/Fas Ligand Pathway, Apoptosis, and Clonal Anergy Involved in Systemic Acetylcholine Receptor T Cell Epitope Tolerance.

C. Deng, E. Goluszko, and P. Christadoss (2001)
J. Immunol. 166, 3458-3467
 |  Abstract »  |  Full Text »  |  PDF »

Effective Antigen-Specific Immunotherapy in the Marmoset Model of Multiple Sclerosis.

H. I. McFarland, A. A. Lobito, M. M. Johnson, G. R. Palardy, C. S. K. Yee, E. K. Jordan, J. A. Frank, N. Tresser, C. P. Genain, J. P. Mueller, et al. (2001)
J. Immunol. 166, 2116-2121
 |  Abstract »  |  Full Text »  |  PDF »

Negative Selection during the Peripheral Immune Response to Antigen.

S. M. Anderton, C. G. Radu, P. A. Lowrey, E. S. Ward, and D. C. Wraith (2001)
J. Exp. Med. 193, 1-12
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Molecular Mechanisms of High-Dose Antigen Therapy in Experimental Autoimmune Encephalomyelitis: Rapid Induction of Th1-Type Cytokines and Inducible Nitric Oxide Synthase.

A. Weishaupt, S. Jander, W. Bruck, T. Kuhlmann, M. Stienekemeier, T. Hartung, K. V. Toyka, G. Stoll, and R. Gold (2000)
J. Immunol. 165, 7157-7163
 |  Abstract »  |  Full Text »  |  PDF »

Non-Fc Receptor-Binding Humanized Anti-CD3 Antibodies Induce Apoptosis of Activated Human T Cells.

P. A. Carpenter, S. Pavlovic, J. Y. Tso, O. W. Press, T. Gooley, X.-Z. Yu, and C. Anasetti (2000)
J. Immunol. 165, 6205-6213
 |  Abstract »  |  Full Text »  |  PDF »

Inducing Tolerance by Intranasal Administration of Long Peptides in Naive and Primed CBA/J Mice.

M. Astori, C. von Garnier, A. Kettner, N. Dufour, G. Corradin, and F. Spertini (2000)
J. Immunol. 165, 3497-3505
 |  Abstract »  |  Full Text »  |  PDF »

Heterogeneous Effects of IL-2 on Collagen-Induced Arthritis.

S. Thornton, G. P. Boivin, K. N. Kim, F. D. Finkelman, and R. Hirsch (2000)
J. Immunol. 165, 1557-1563
 |  Abstract »  |  Full Text »  |  PDF »

Systemic Administration of Agonist Peptide Blocks the Progression of Spontaneous CD8-Mediated Autoimmune Diabetes in Transgenic Mice Without Bystander Damage.

N. Bercovici, A. Heurtier, C. Vizler, N. Pardigon, C. Cambouris, P. Desreumaux, and R. Liblau (2000)
J. Immunol. 165, 202-210
 |  Abstract »  |  Full Text »  |  PDF »

Coupling of Peripheral Tolerance to Endogenous Interleukin 10 Promotes Effective Modulation of Myelin-Activated T Cells and Ameliorates Experimental Allergic Encephalomyelitis.

K. L. Legge, B. Min, J. J. Bell, J. C. Caprio, L. Li, R. K. Gregg, and H. Zaghouani (2000)
J. Exp. Med. 191, 2039-2052
 |  Abstract »  |  Full Text »  |  PDF »

Induction and Suppression of an Autoimmune Disease by Oligomerized T Cell Epitopes: Enhanced in Vivo Potency of Encephalitogenic Peptides.

K. Falk, O. Rotzschke, L. Santambrogio, M. E. Dorf, C. Brosnan, and J. L. Strominger (2000)
J. Exp. Med. 191, 717-730
 |  Abstract »  |  Full Text »  |  PDF »

The role of CTLA-4 in tolerance induction and T cell differentiation in experimental autoimmune encephalomyelitis: i.p. antigen administration.

R. B. Ratts, L. R. Arredondo, P. Bittner, P. J. Perrin, A. E. Lovett-Racke, and M. K. Racke (1999)
Int. Immunol. 11, 1881-1888
 |  Abstract »  |  Full Text »  |  PDF »

The role of CTLA-4 in tolerance induction and Ttigen administration cell differentiation in experimental autoimmune encephalomyelitis: i.v. antigen administration.

R. B. Ratts, L. R. Arredondo, P. Bittner, P. J. Perrin, A. E. Lovett-Racke, and M. K. Racke (1999)
Int. Immunol. 11, 1889-1896
 |  Abstract »  |  Full Text »  |  PDF »

Sustained Activation of the Raf-MEK-ERK Pathway Elicits Cytokine Unresponsiveness in T Cells.

D. Chen, V. Heath, A. O'Garra, J. Johnston, and M. McMahon (1999)
J. Immunol. 163, 5796-5805
 |  Abstract »  |  Full Text »  |  PDF »

Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: a role for IL-10.

C. Burkhart, G. Y. Liu, S. M. Anderton, B. Metzler, and D. C. Wraith (1999)
Int. Immunol. 11, 1625-1634
 |  Abstract »  |  Full Text »  |  PDF »

Age Dependence of Clinical and Pathological Manifestations of Autoimmune Demyelination : Implications for Multiple Sclerosis.

M. E. Smith, N. L. Eller, H. F. McFarland, M. K. Racke, and C. S. Raine (1999)
Am. J. Pathol. 155, 1147-1161
 |  Abstract »  |  Full Text »  |  PDF »

Protective Antiviral Cytotoxic T Cell Memory Is Most Efficiently Maintained by Restimulation Via Dendritic Cells.

B. Ludewig, S. Oehen, F. Barchiesi, R. A. Schwendener, H. Hengartner, and R. M. Zinkernagel (1999)
J. Immunol. 163, 1839-1844
 |  Abstract »  |  Full Text »  |  PDF »

Induction of hyporesponsiveness to intact foreign protein via retroviral-mediated gene expression: The IgG scaffold is important for induction and maintenance of immune hyporesponsiveness.

Y. Kang, M. Melo, E. Deng, R. Tisch, M. El-Amine, and D. W. Scott (1999)
PNAS 96, 8609-8614
 |  Abstract »  |  Full Text »  |  PDF »

Resistance of Crohn's Disease T Cells to Multiple Apoptotic Signals Is Associated with a Bcl-2/Bax Mucosal Imbalance.

K. Ina, J. Itoh, K. Fukushima, K. Kusugami, T. Yamaguchi, K. Kyokane, A. Imada, D. G. Binion, A. Musso, G. A. West, et al. (1999)
J. Immunol. 163, 1081-1090
 |  Abstract »  |  Full Text »  |  PDF »

Candidate autoantigens in multiple sclerosis.

S. Schmidt (1999)
Multiple Sclerosis 5, 147-160
 |  Abstract »  |  PDF »

Expansion of neonatal tolerance to self in adult life: II. Tolerance preferentially spreads in an intramolecular manner.

N. Grabie and N. Karin (1999)
Int. Immunol. 11, 907-913
 |  Abstract »  |  Full Text »  |  PDF »

HLA-Derived Peptides as Novel Immunomodulatory Therapeutics.

B. MURPHY and A. M. KRENSKY (1999)
J. Am. Soc. Nephrol. 10, 1346-1355
 |  Abstract »  |  Full Text »

Mechanisms of Nasal Tolerance Induction in Experimental Autoimmune Myasthenia Gravis: Identification of Regulatory Cells.

F.-D. Shi, H. Li, H. Wang, X. Bai, P. H. van der Meide, H. Link, and H.-G. Ljunggren (1999)
J. Immunol. 162, 5757-5763
 |  Abstract »  |  Full Text »  |  PDF »

In vivo elimination of viral superantigen-activated CD4+ T cells: apoptosis occurs at a distance from the activation site.

A. Le Bon, A.-C. Wache, and M. Papiernik (1999)
Int. Immunol. 11, 373-382
 |  Abstract »  |  Full Text »  |  PDF »

Determinant Spreading Associated with Demyelination in a Nonhuman Primate Model of Multiple Sclerosis.

H. I. McFarland, A. A. Lobito, M. M. Johnson, J. T. Nyswaner, J. A. Frank, G. R. Palardy, N. Tresser, C. P. Genain, J. P. Mueller, L. A. Matis, et al. (1999)
J. Immunol. 162, 2384-2390
 |  Abstract »  |  Full Text »  |  PDF »

Materials and Methods.

(1999)
Multiple Sclerosis 5, 003-9
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The PTK-STAT Signaling Pathway Has Essential Roles in T-cell Activation in Response to Antigen Stimulation.

T. WELTE, D. LEITENBERG, B.N. DITTEL, B.K. AL-RAMADI, W.R. HANSEN, B. XIE, C.A. JANEWAY, A.L.M. BOTHWELL, K. BOTTOMLY, and X.Y. FU (1999)
Cold Spring Harb Symp Quant Biol 64, 291-302
 |  Abstract »  |  PDF »

Antigen Localization and Migration in Immunity and Tolerance.

T. E. Starzl and R. M. Zinkernagel (1998)
N. Engl. J. Med. 339, 1905-1913
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Tolerant CD8 T Cells Induced by Multiple Injections of Peptide Antigen Show Impaired TCR Signaling and Altered Proliferative Responses In Vitro and In Vivo.

P. M. Dubois, M. Pihlgren, M. Tomkowiak, M. Van Mechelen, and J. Marvel (1998)
J. Immunol. 161, 5260-5267
 |  Abstract »  |  Full Text »  |  PDF »

Apoptotic Death of CD8+ T Lymphocytes After Immunization: Induction of a Suppressive Population of Mac-1+/Gr-1+ Cells.

V. Bronte, M. Wang, W. W. Overwijk, D. R. Surman, F. Pericle, S. A. Rosenberg, and N. P. Restifo (1998)
J. Immunol. 161, 5313-5320
 |  Abstract »  |  Full Text »  |  PDF »

Supraoptimal Peptide-Major Histocompatibility Complex Causes a Decrease in Bcl-2 Levels and Allows Tumor Necrosis Factor {alpha} Receptor II-mediated Apoptosis of Cytotoxic T Lymphocytes.

M. A. Alexander-Miller, M. A. Derby, A. Sarin, P. A. Henkart, and J. A. Berzofsky (1998)
J. Exp. Med. 188, 1391-1399
 |  Abstract »  |  Full Text »  |  PDF »

T-Cell Apoptosis in Inflammatory Brain Lesions : Destruction of T Cells Does Not Depend on Antigen Recognition.

J. Bauer, M. Bradl, W. F. Hickey, S. Forss-Petter, H. Breitschopf, C. Linington, H. Wekerle, and H. Lassmann (1998)
Am. J. Pathol. 153, 715-724
 |  Abstract »  |  Full Text »  |  PDF »

Peripheral Immune Tolerance Blocks Clonal Expansion but Fails to Prevent the Differentiation of Th1 Cells.

E.-N. Malvey, M. K. Jenkins, and D. L. Mueller (1998)
J. Immunol. 161, 2168-2177
 |  Abstract »  |  Full Text »  |  PDF »

Impaired Alloantigen-Mediated T Cell Apoptosis and Failure To Induce Long-Term Allograft Survival in IL-2-Deficient Mice.

Z. Dai, B. T. Konieczny, F. K. Baddoura, and F. G. Lakkis (1998)
J. Immunol. 161, 1659-1663
 |  Abstract »  |  Full Text »  |  PDF »

Fas Ligand-Mediated Lysis of Self Bystander Targets by Human Papillomavirus-Specific CD8+ Cytotoxic T Lymphocytes.

M. J. Smyth, E. Krasovskis, and R. W. Johnstone (1998)
J. Virol. 72, 5948-5954
 |  Abstract »  |  Full Text »  |  PDF »

Direct Evidence That Functionally Impaired CD4+ T Cells Persist In Vivo Following Induction of Peripheral Tolerance.

K. A. Pape, R. Merica, A. Mondino, A. Khoruts, and M. K. Jenkins (1998)
J. Immunol. 160, 4719-4729
 |  Abstract »  |  Full Text »  |  PDF »

A Noncomitogenic CD2R Monoclonal Antibody Induces Apoptosis of Activated T Cells by a CD95/CD95-L-Dependent Pathway.

S. Fournel, E. Robinet, N. Bonnefoy-Berard, O. Assossou, M. Flacher, H. Waldmann, G. Bismuth, and J.-P. Revillard (1998)
J. Immunol. 160, 4313-4321
 |  Abstract »  |  Full Text »  |  PDF »

MHC Class I/Peptide Stability: Implications for Immunodominance, In Vitro Proliferation, and Diversity of Responding CTL.

D. H. Busch and E. G. Pamer (1998)
J. Immunol. 160, 4441-4448
 |  Abstract »  |  Full Text »  |  PDF »

Selective Induction of Apoptosis in Mature T Lymphocytes by Variant T Cell Receptor Ligands.

B. Combadiere, C. R. e Sousa, R. N. Germain, and M. J. Lenardo (1998)
J. Exp. Med. 187, 349-355
 |  Abstract »  |  Full Text »  |  PDF »

Ovalbumin-Specific, MHC Class I-Restricted, {alpha}{beta}-Positive, Tc1 and Tc0 CD8+ T Cell Clones Mediate the In Vivo Inhibition of Rat IgE.

P. A. MacAry, B. J. Holmes, and D. M. Kemeny (1998)
J. Immunol. 160, 580-587
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T Cell Growth Cytokines Cause the Superinduction of Molecules Mediating Antigen-Induced T Lymphocyte Death.

L. Zheng, C. L. Trageser, D. M. Willerford, and M. J. Lenardo (1998)
J. Immunol. 160, 763-769
 |  Abstract »  |  Full Text »  |  PDF »

Functional cleavage of the common cytokine receptor gamma  chain (gamma c) by calpain.

M. Noguchi, A. Sarin, M. J. Aman, H. Nakajima, E. W. Shores, P. A. Henkart, and W. J. Leonard (1997)
PNAS 94, 11534-11539
 |  Abstract »  |  Full Text »  |  PDF »

Tolerance Induction and Autoimmune Encephalomyelitis Amelioration After Administration of Myelin Basic Protein-derived Peptide.

S. Marusic and S. Tonegawa (1997)
J. Exp. Med. 186, 507-515
 |  Abstract »  |  Full Text »  |  PDF »

Class I-restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells.

C. Kurts, H. Kosaka, F. R. Carbone, J. F.A.P. Miller, and W. R. Heath (1997)
J. Exp. Med. 186, 239-245
 |  Abstract »  |  Full Text »  |  PDF »

Unequal Death in T Helper Cell (Th)1 and Th2 Effectors: Th1, but not Th2, Effectors Undergo Rapid Fas/FasL-mediated Apoptosis.

X. Zhang, T. Brunner, L. Carter, R. W. Dutton, P. Rogers, L. Bradley, T. Sato, J. C. Reed, D. Green, and S. L. Swain (1997)
J. Exp. Med. 185, 1837-1849
 |  Abstract »  |  Full Text »  |  PDF »

Direct Ex Vivo Analysis of Activated, Fas-sensitive Autoreactive T Cells in Human Autoimmune Disease.

K. D. Bieganowska, L. J. Ausubel, Y. Modabber, E. Slovik, W. Messersmith, and D. A. Hafler (1997)
J. Exp. Med. 185, 1585-1594
 |  Abstract »  |  Full Text »  |  PDF »

Peptide-induced nasal tolerance for a mycobacterial heat shock protein 60 T cell epitope in rats suppresses both adjuvant arthritis and nonmicrobially induced experimental arthritis.

B. J. Prakken, R. van der Zee, S. M. Anderton, P. J. S. van Kooten, W. Kuis, and W. van Eden (1997)
PNAS 94, 3284-3289
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Antigen therapy eliminates T cell inflammation by apoptosis: Effective treatment of experimental autoimmune neuritis with recombinant myelin protein P2.

A. Weishaupt, R. Gold, S. Gaupp, G. Giegerich, H.-P. Hartung, and K. V. Toyka (1997)
PNAS 94, 1338-1343
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Induction of Apoptosis and T Helper 2 (Th2) Responses Correlates with Peptide Affinity for the Major Histocompatibility Complex in Self-reactive T Cell Receptor Transgenic Mice.

C.I. Pearson, W. van Ewijk, and H.O. McDevitt (1997)
J. Exp. Med. 185, 583-600
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The Ly-49D Receptor Activates Murine Natural Killer Cells.

L.H. Mason, S.K. Anderson, W.M. Yokoyama, H.R.C. Smith, R. Winkler-Pickett, and J.R. Ortaldo (1996)
J. Exp. Med. 184, 2119-2128
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D4-GDI, a Substrate of CPP32, Is Proteolyzed during Fas-induced Apoptosis.

S. Na, T.-H. Chuang, A. Cunningham, T. G. Turi, J. H. Hanke, G. M. Bokoch, and D. E. Danley (1996)
J. Biol. Chem. 271, 11209-11213
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Apoptosis in the pathogenesis and treatment of disease.

C. Thompson (1995)
Science 267, 1456-1462
 |  Abstract »  |  PDF »

Antigen challenge leads to in vivo activation and elimination of highly polarized TH1 memory T cells.

N. Hayashi, D. Liu, B. Min, S. Z. Ben-Sasson, and W. E. Paul (2002)
PNAS 99, 6187-6191
 |  Abstract »  |  Full Text »  |  PDF »

Specific treatment of autoimmunity with recombinant invariant chains in which CLIP is replaced by self-epitopes.

F. Bischof, W. Wienhold, C. Wirblich, G. Malcherek, O. Zevering, A. M. Kruisbeek, and A. Melms (2001)
PNAS 98, 12168-12173
 |  Abstract »  |  Full Text »  |  PDF »

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